76results about How to "Stable particle size distribution" patented technology

The invention discloses a cross-linked sodium hyaluronate biomembrane and a preparation method thereof. The cross-linked sodium hyaluronate biomembrane is prepared by: conducting freeze drying on a prepared gel with a crosslinking degree up to 60%-80%, and then pressing the freeze-dried gel into a membrane. The preparation method of the gel includes: acquiring cross-linked sodium hyaluronate dry powder, then washing the collected sieved powder by dimethyl sulfoxide (DMSO); washing the DMSO washed powder by ethanol; then conducting vacuum drying to obtain cross-linked sodium hyaluronate powder; fully swelling the powder, performing purification for 6-10h at a room temperature of 15-35DEG C, then carrying out homogenization micronization treatment in a high-speed dispersion machine, and then collecting the uniform gel particles, thus obtaining the cross-linked sodium hyaluronate gel used for biomembrane preparation. The cross-linked sodium hyaluronate biomembrane prepared by the method provided by the invention has is pyrogen-free, sterile, free of residual crosslinking agent, and has low cytotoxicity. With long residence time in vivo, the biomembrane has good anti-adhesion effect, good biocompatibility and tissue repair performance.

The invention discloses a preparation method of a nano silver chloride / chitosan fiber anti-bacterial dressing. The method includes following steps: (1) pretreatment of a surface of a chitosan fiber nonwoven cloth: spraying an acid solution onto the surface of the chitosan fiber to enable the acid solution to infiltrate into the surface of the nonwoven cloth, treating the nonwoven cloth for 1-5 min and then washing the nonwoven cloth with deionized water; (2) soaking the pre-treated nonwoven cloth in a silver nitrate solution with a concentration of 0.0048-0.036 mmol / mL with a normal-temperature shaking operation for 30 min; (3) draining the nonwoven cloth and air-drying the nonwoven cloth until the water content is 30-40%; (4) uniformly spraying a 0.036-0.27 mmol / mL sodium chloride solution having an equal saturate water absorption amount onto the surface of the nonwoven cloth, wherein molar number of the sodium chloride is 1.2-1.5 times than that of adsorbed silver, and carrying out a reaction for 5-10 min; and (5) spraying deionized water and quickly washing the nonwoven cloth, draining the nonwoven cloth and vacuum-drying the nonwoven cloth at 50-60 DEG C. The preparation method is high in silver recycle ratio. A nano silver chloride anti-bacterial material is stable in physical and chemical performances, is excellent in anti-bacterial performance or bacteria-inhibiting peroformance, is good in fixation performance of silver chloride particles to the chitosan fiber, and can be used as a medical wound dressing.

The liquid is supplied to an emitter electrode which is provided at a tip of a liquid carrier, receives a high voltage, is electrical-charged, and discharged as a mist of charged minute water particles of nanometer order from the emitter electrode. The emitter electrode discharges the mist of the charged minute water particles of micron order at the same time by a pressure which is applied to the liquid which is supplied to the tip of the emitter electrode. An electrostatically atomizing device supplies liquid to an emitter electrode of a tip of a liquid carrier, applies the high voltage to the liquid, electrically-charges the liquid, and causes the emitter electrode to discharge a mist of charged minute water particles of nanometer order. In addition, the electrostatically atomizing device applies a pressure to the emitter electrode and causes the emitter electrode to discharge a mist of the charged minute water particles of micron order. The electrostatically atomizing device is able to humidify a space by the mist of the charged minute water particles of micron order as well as is able to decompose harmful substances in the space, is able to sterilize and deodorize the substances in the space by radicals which is included by the mist of the charged minute water particles of nanometer order.

The invention discloses a carbon resistance superfine nano wolfram carbide (WC) material as well as a preparation method and application thereof. The preparation method of the carbon resistance superfine nano WC material comprises the following steps: (1) adding a deionized water solution of a wolfram source in a solution prepared from ethanol, stronger ammonia water and a surfactant, wherein the wolfram source is ammonium metatungstate, sodium tungstate or tungsten chloride, the surfactant is sodium dodecyl benzene sulfonate, hexadecyl trimethyl ammonium bromide or P123, stirring the solution uniformly, adding resorcinol to the solution, stirring uniformly and then adding formaldehyde, and stirring for 8-28 hours at the room temperature to obtain the mixed solution; (2) performing a hydrothermal reaction on the mixed solution, and drying the solution to obtain a mixed polymer; (3) performing high-temperature carbonization on the mixed polymer in a CO atmosphere to obtain the carbon resistance superfine nano WC material. The WC material can enable the WC particles to keep stable in the high temperature process without secondary agglomeration; the WC material can be taken as an electrocatalyst to be applied to an electrocatalysis nitroreduction reaction, or can also be taken as a carrier to prepare a platinum-carried catalyst, and the prepared platinum-carried catalyst can be applied to anode catalysis of a methanol fuel cell.

The invention relates to a method for preparing a phosphate series lithium ion battery anode material, comprising the following steps: preparing one or more of divalent manganese source compound, ferrum source compound, nickel source compound or cobalt source compound into a mixed solution; adding oxalic acid or oxalate, acid and urea, and slowly hydrolyzing the urea by controlling the reaction temperature and time; causing the pH value of the system to rise to reach the condition of homogeneous precipitation; after the reaction, filtering, washing and drying to obtain a precursor; evenly mixing and carrying out ball milling on the precursor, a lithium source and a phosphorous source; and calcining the mixture under the non-oxidability atmosphere to prepare the unitary or multielement phosphate series lithium ion battery anode material. The precursor prepared with the method has the advantages of stable ingredient proportion, even granularity distribution, good consistency and simple synthetic technology, does not need to consider the influence of flow rate and agitation and is suitable for industrial production. The synthesized battery anode material is the phosphate compound with an olivine structure, the average grain size of the primary particle is 100-500nm, and the battery anode material has good electrochemistry property.

The invention relates to medicinal low-release micro particles and in particular relates to triptorelin slow-release micro particles and a preparation method thereof. The triptorelin slow-release micro particles comprise the following components in percentage by weight: 0.5-20% of triptorelin, 79-99% of PLGA and 0.1-1% of poloxamer. The preparation method of the triptorelin slow-release micro particles comprises the steps of mixing all the components, then putting the mixture into a hot melt extruder, and performing heating melting, extrusion and low-temperature crushing in the hot melt extruder. The triptorelin slow-release micro particles provided by the invention are good in shape, high in entrapment efficiency, good in drug loading capacity and stable in releasing. Moreover, the triptorelin slow-release micro particles are simple in synthetic process, are harmless, generate nontoxic products after degradation, and are stable in quality.

The invention discloses a method for preparing a nanoscale anionic laminar material continuously, which mainly comprises the steps of reacting, filtering, washing and drying. Compared with the conventional method for preparing the anionic laminar material in China, the method has the following advantages: (1) a helix channel rotating bed high gravity reactor is adopted to enable nucleus formation to be formed in a uniform micro hybrid environment quickly with a narrowed particle size distribution, the reaction solution in the reactor is kept under a stable high pH value condition by condensing NH3 so as to avoid generating an impurity phase, the reaction time is short and the operation is simple; (2) crystal seeds are added during reaction to greatly reduce the induction period of nucleus formation and accelerate nucleus formation, the crystallinity is high, the particle size distribution is more uniform, the size and distribution of newly generated particles can be controlled according to the particle size of the added crystal seeds, and thus, the particle size is controllable; (3) a crystallization process is not required for product post processing; and (4), the process is quick and allows for continuous production, and the average particle size of the prepared anionic laminar material is 30 to 90 nanometers.

The invention relates to the technical field of cosmetics, and specifically relates to a preparation method of grape seed procyanidin sun cream. Aiming at the characteristic of a plant sun cream, namely a grape seed procyanidin extract, the biological activity of procyanidin as an effective component is maintained to the maximum extent by adopting appropriate adding forms and adding methods. The technical scheme adopted by the invention comprises the following operational steps: I, screening grape brewing dregs, separating and sorting grape seeds with qualified quality, and crushing and degreasing to obtain grape seed degreased powder; II, preparing the grape seed procyanidin extract; III, preparing the sun cream; IV, packaging.

The invention relates to a preparing method for a composite phosphate series lithium ion battery anode material. Soluble ferrous salt and soluble transition metallic nickel salt or cobalt salt or manganese salt are prepared into a solution, and acid and urea are added to prepare a mixed solution; a precipitating agent is added into the mixed solution for reaction to prepare a composite oxalate precursor; the precursor, a lithium source and a phosphorus source are uniformly mixed in a ball milled mode, and the composite phosphate series lithium ion battery anode material is prepared under inertia or weak reducing atmosphere. According to the method, the urea water solution is used and will be hydrolyzed slowly under the acid and urea enzyme catalysis or heating conditions, and as the urea hydrolysis speed is low and a hydrolysis product is simple and easy to volatilize, the urea water solution can be used for uniform precipitation of elements and ions. The first-time charge-discharge specific capacity of 0.1C multiplying power of the obtained product at the room temperature can reach about 160 mAh / g, and cycle performance and charge-discharge performance are good.

The invention relates to a preparation method of a compound phosphate-series positive electrode material for a lithium-ion battery. The method comprises the following steps: preparing a solution from a soluble bivalent iron salt and a soluble transition metal nickel salt, cobalt salt or manganese salt, and then adding an acid and urea to prepare a mixed solution; adding a precipitant to the mixed solution for reaction and preparing a mixed oxalate precursor; and carrying out ball-mill mixing on the precursor, a lithium source and a phosphorus source evenly and preparing the compound phosphate-series positive electrode material for the lithium-ion battery in an inert or weak reductive atmosphere. The used aqueous urea solution is slowly hydrolyzed under the acid, alkali and urease catalysis or heating conditions. The urea hydrolysis rate is low and the hydrolysis product is simple and easy to volatilize, so that the aqueous urea solution can be applied to homogeneous precipitation of elements and ions. The first charge and discharge specific capacity of the obtained product at a room temperature and 0.1C rate can reach about 160mAh / g; and the compound phosphate-series positive electrode material is good in cycle performance and charge and discharge performance.

The invention relates to low-cost lead-free soldering flux alloy powder for an LED (light emitting diode) and a preparation method of the alloy powder, and belongs to the field of soft soldering fluxes and application. The alloy powder consists of the following components in percentage by weight: 6.5-9.5 percent of Zn, 1.0-3.0 percent of Bi, 0.5-1.0 percent of Cu and the balance being Sn. The preparation method comprises the steps of putting the raw materials into an induction furnace crucible after burdening according to the weight percentage; pre-vacuumizing a smelting chamber and an atomization chamber, and filling the chambers with inert protection gas; performing heating smelting on the raw materials by an induction coil; feeding high-pressure atomized gas into a nozzle, wherein the high-pressure atomized gas crushes alloy liquid flow which is in a smelted state after falling into the atomization chamber from the bottom of the crucible, and highly atomized liquid drops are formed, fall off and are cooled into alloy powder in an atomization tank; grading the alloy powder which is cooled through screening, and performing vacuumizing nitrogen-filled packaging. The soldering flux alloy powder prepared by the method disclosed by the invention is spherical and is high in oxidization resistance and corrosion resistance and excellent in mechanical property.

The invention relates to a lipid targeted ultrasound contrast agent and a preparation method thereof. The preparation method of the contrast agent comprises the following steps: adding synthetic phospholipids and poloxamer to deionized double distilled water and uniformly mixing the mixed liquid to prepare a mixed suspension A; adding palmitic acid which combines probe polypeptide to absolute alcohol which is an organic solvent to dissolve the palmitic acid so as to prepare a solution B; ultrasonically treating the mixed suspension A, meanwhile, dropping the solution B into the mixed suspension A, and uniformly mixing the mixed suspension A and the solution B to obtain a settled solution C; adding PEG-4000 to the settled solution C to dissolve the PEG-4000; introducing perfluoropropane gasinto the settled solution C, and at the same time of sufficient saturation, applying high-speed mechanical shearing equipment to process the settled solution C to form a microvesicle mixed suspensionwith an average grain diameter of 1-4 micrometers. Prepared ultrasound microvesicles have proper size, uniform and stable grain diameter distribution, proper concentration and high targeted probe binding rate; and reagent materials used for connecting ligands except preparation raw materials of the contrast agent do not need to be added. The invention has simple preparation method, small interference to the characteristics of the microvesicles and is beneficial to purify the targeted contrast agent.

The invention relates to a preparation method of polydopamine gelatin microspheres. The preparation method is characterized by comprising the following steps: placing prepared gelatin microspheres into a prepared Tris / HCI buffer solution of which the pH is equal to 8.5; then, adding 2mg / mL of dopamine solution; stirring at the temperature of 37 DEG C for 12 to 24 hours; centrifuging and washing with deionized water three times; drying in the air to obtain the polydopamine-coated gelatin microspheres. The gelatin microspheres are covered well with polydopamine, so that the chemical multifunctionality of the surfaces of the polydopamine gelatin microspheres is enhanced, and Vc can be loaded successfully. The polydopamine gelatin microspheres have a potential value on the aspect of drug sustained release.

The invention relates to an ultrasonic contrast agent of a uterus oviduct tract and a preparation method of the ultrasonic contrast agent. The ultrasonic contrast agent is prepared from the following components: a first component is a carrier and is composed of phospholipid, polyethylene glycol or a derivative thereof and polymerized phospholipid connected with a specific ligand at the weight ratio of (0.5 to 2):(0.005 to 0.02):(0.003 to 0.007); a second component is a phospholipid stabilizer; a third component is a biological solvent; a fourth component is a fluorocarbon gas; the weight percent ratio of the first component to the second component to the third component is (0.0005 to 0.002):(0.000005 to 0.00002):(0.5 to 2); the concentration of the fourth component which is gas is 10<8>-10<9> / mL.

The invention relates to a ginsenoside C-K monohydrate crystal and a preparation method thereof. One molecule of ginsenoside C-K monohydrate contains one molecule of ginsenoside C-K and molecule of water. The preparation method comprises the following steps of: adding ginsenoside C-K raw material in a mixed solvent of acetonitrile and water, adding seed crystal in a supersaturated solution of ginsenoside C-K in a cooling process, inducing the seed crystal to separate out crystals, and promoting the growth of the crystals. The 2 theta value of the obtained crystal product of ginsenoside C-K monohydrate crystal is 6.3+ / -0.2, 11.2+ / -0.2, 12.7+ / -0.2, 13.3+ / -0.2, 15.8+ / -0.2, 16.2+ / -0.2, 17.4+ / -0.2, 20.0+ / -0.2, 20.8+ / -0.2, 22.6+ / -0.2, 23.6+ / -0.2, 24.3+ / -0.2 and 25.6+ / -0.2. By the preparation method, the crystallization yield of C-K is improved and the stability of the product is improved.

The present invention relates to a particulate carbon material that can be produced from renewable raw materials, in particular from biomass containing lignin, comprising: a 14C content that corresponds to that of the renewable raw materials, said content being preferably greater than 0.20 Bq / g carbon, especially preferably greater than 0.23 Bq / g carbon, but preferably less than 0.45 Bq / g carbon in each case; a carbon content in relation to the ash-free dry substance of between 60 ma.% and 80 ma. %; an STSA surface area of the primary particles of at least 5 m2 / g and at most 200 m2 / g; and an oil absorption value (OAN) of between 50 ml / 100g and 150ml / 100g. The present invention also relates to a method for producing said carbon material and to the use thereof.

The invention provides gadolinium zirconate thermal barrier coating ceramic granulation powder for atmospheric plasma spraying and a preparation method thereof, and belongs to the technical field of ceramic powder. Hydroxide with higher activity and lower hardness is adopted as a raw material, zirconium hydroxide and gadolinium hydroxide are subjected to high-energy ball milling, raw material powder obtained through treatment can achieve a solid-phase reaction at the low roasting temperature (800-1100 DEG C), meanwhile, the roasted gadolinium zirconate clinker is treated through high-energy ball milling, the gadolinium zirconate powder with the cubic pyrochlore structure, which is smaller in particle size (nanoscale), more uniform in particle size distribution and stable in structure, can be obtained; the defects of high reaction temperature, large particle size of prepared powder, non-uniformity and the like of the traditional solid-phase reaction method are overcome; polluting ions such as acid radicals and ammonia radicals are not introduced, the method has the advantages of energy conservation and environmental protection, and the ceramic powder with the particle size close to that of powder prepared through a chemical precipitation method can be obtained.

The invention provides a composition of calcium carbonate and organic elastomer and a preparation method thereof. The composition of calcium carbonate and organic elastomer includes ingredients of, by weight, 45-95% of calcium carbonate and 5-55% of organic elastomer particle. A preparation technology of the invention is simple. A filler of calcium carbonate itself is used as a separant and a flocculating agent, and the composition has no impurity, so as to substantially lower costs and facilitate industrialization. The composition has good physical mechanical property, good fluidity and storage stability, and can be widely applied to fields of rubber product, adhesive and polymer modification to enhance or improve comprehensive performances of a matrix material. For instance, the composition can be used in a rubber product to substantially enhance mechanical properties, in a friction material as a phenolic aldehyde adhesive improving component to substantially improve flexural modulus of the friction material, and in polymer modification to enhance and toughen polyvinyl chloride, enhance high and low temperature resistance performance of asphalt, improve tensile strength, elongation and impact intensity of phenolic resin.

The invention relates to a preparation method and application of a visible light response magnetic metal organic framework material; and the preparation method comprises the preparation steps of: firstly, preparing by adopting a solvothermal method to respectively obtain a polyamine metal organic framework material and nano Fe3O4; then introducing an epoxy group on the surface of the nano Fe3O4 byan ultrasonic assisted polymerization method to prepare epoxy functional nano Fe3O4; and then carrying out induction open-loop self-assembling on the epoxy functional nano Fe3O4 and the polyamine metal organic framework material by carboxylic acid to obtain the amino / carboxyl modified magnetic metal organic framework material. The product obtained by the method disclosed by the invention is in apowder form, is medium brown, and is uniform in particle size distribution and stable in property. The defect of solution agglomeration of a material material is overcome, and the prepared material isgood in dispersibility, high in magnetic performance, rapid in response, easy in obtaining of the raw materials and high in yield; and the visible light response magnetic metal organic framework material has visible light response, magnetic and accurate controllable topological structures, has a wide pH application range, achieves visible light catalysis and magnetism dual functions of the material and is beneficial to separation and recovery of a catalyst.

The invention relates to a method for preparing water-soluble fluorescent carbon dots based on chitosan oligosaccharide-microwave assistance, which is designed for the situation of complicated operation, difficult separation, low yield, non-uniform particle size distribution, poor stability and the like in fluorescent carbon dot preparation. In the method, chitosan oligosaccharide serves as a carbon source, water serves as a solvent and acetic acid serves as a cosolvent, and a microwave method is adopted for preparation; and the powder of fluorescent carbon dots is prepared by alcohol precipitation, separation and drying. In the invention, the prepared fluorescent carbon dots have good water solubility, stable fluorescence, uniform particle size distribution and high purity; the equipment is simple and convenient to operate and suitable for large-scale production; and the product has a good application prospect in the fields such as ion detection, bioimaging, fluorescent materials and the like.

The invention discloses a quantum dot composite material having a dual-component substrate and a preparation method thereof. The quantum dot composite material comprises a transmittance base material, a microcapsule layer and a quantum dot layer, the microcapsule layer is positioned on the transmittance base material, the quantum dot layer is positioned on the microcapsule layer, the microcapsule layer is formed by the microcapsules through self assembly, the quantum dot layer is formed by quantum dots through self assembly, the microcapsule comprises a shell layer and a core, the shell layer contains polystyrene and silica, and the core is paraffin. The quantum dot composite material can keep excellent properties of high luminescence efficiency and photochemical stability of common quantum dots, the illumination intensity also has a specific temperature sensitive value, and thus the quantum dot composite material can be used for associating and monitoring the specific temperature. The quantum dot composite material also has good reuse performance and no shedding of the quantum dots.

The invention discloses a chitosan nano particle which comprises the following raw materials in percentage by weight: 0.5-5% of chitosan, 1-10% of cosolvent, 0-5% of antifreezing agent, 0.1-1% of surfactant, 0.1-0.5% of emulsifier, 40-60% of buffer solution and the balance of water. The invention also provides a biological pesticide preparation for controlling tobacco caterpillars and a preparation method thereof. The biological pesticide preparation mainly comprises the following components in percentage by weight: (A) 0.05-15% of active component: a siRNA (small interfering ribonucleic acid) is designed and synthesized in accordance with a tobacco caterpillar high-efficiency killing target gene and is a 15-50nt double-chain RNA; (B) 19.95-55% of solvent; and (C) 30-80% of chitosan nano particle. The chitosan nano particle ensures that the stability and the control effect of the biological pesticide preparation are better.

The invention relates to a diamond synthesis device with a super-large cavity. The diamond synthesis device comprises the super-large cavity which is provided with an upper iron cup and a lower iron cup along the axial direction; a heating plate is arranged between the bottom of the upper iron cup and the bottom of the lower iron cup; the opening ends of the iron cups are respectively with a composite layer; an iron bowl is arranged on the outer layer of each composite layer, and the inner layer of each composite layer is of a composite structure formed by a dolomite cake, a graphite conductive ring and a dolomite ring; each graphite conductive ring is electrically connected with one end of a graphite column inside the corresponding iron cup through a piece of graphite paper, and the other end of the graphite column is electrically connected with the bottom of the corresponding iron cup; the super-large cavity is formed along the radial direction, the inner layer of the cavity is the iron cup wall, the middle layer of the cavity is formed by dolomite, and the outer layer of the cavity is formed by pyrophyllite. The diamond synthesis device has the advantages that the diamond synthesis device can be directly heated, and current passes through the graphite columns; conductive materials at two ends are changed into nonmetal materials from metal materials, so that the heat retaining property and the stability are greatly improved. The diamond synthesis device can be applied to large press equipment on a large scale, the forbidden zone that a super-large cavity for synthesizing diamonds cannot be directly heated is broken through, and the blank in the diamond industry is filled up.

The invention discloses a centrifugal atomization rotating disc, a centrifugal atomization device and a centrifugal atomization method. The centrifugal atomization rotating disc comprises a bracket made of a high-strength material and a disc core made of a high-temperature-resistant and corrosion-resistant material, and the disc core contains high-temperature liquid metal to be centrifugally atomized. The centrifugal atomization rotating disc is made of the high-temperature-resistant and corrosion-resistant material, and the bracket is made of the high-strength material so that the centrifugalatomization rotating disc can be suitable for atomization of high-melting-point liquid metal with the melting point ranging from 500 DEG C to 2000 DEG C; high-temperature liquid metal can be contained in the tops of the disc cores in different forms more conveniently, the surface shapes of the disc cores are quite beneficial for high-temperature metal liquid to stably keep uniform and equal-thickness liquid membranes moving towards the edge of a rotating disc under the effect of the centrifugal force, centrifugal atomization can form metal liquid droplet wires in a filamentous mode as much aspossible, and the liquid metal can be cooled into a geometrical shape which is uniform in size, concentrated in distribution and high in degree of sphericity.

A preparation method of a ternary positive electrode material NCA precursor comprises the following steps: (1) mixing an Ni water-soluble salt, a Co water-soluble salt and an Al water-soluble salt toprepare an aqueous solution, to obtain a mixed ion solution; (2) making the flow rate of the NaOH and NH3.H2O mixed solution constant at 300-600 L / h, continuously adding the mixed ion solution of thestep (1) into a reactor, carrying out equimolar synthetic reaction, constantly adjusting the flow rate to stabilize the pH value of the reaction, and then heating and stirring to obtain a mixed alkalisolution; and (3) carrying out solid-liquid separation of the mixed alkali solution of the step (2), and washing and drying the obtained solid to obtain the ternary positive electrode material NCA precursor.

The invention discloses an anti-wrinkle skin tightening emulsion containing polypeptides. The emulsion contains snake venom peptide in a mass fraction of 0.05-0.1%, acetyl tetrapeptide-2 in a mass fraction of 0.05-0.15%, hexapeptide-11 in a mass fraction of 0.1-0.15%, and acetyl octapeptide-3 in a mass fraction of 0.1-0.2%. According to the anti-wrinkle skin tightening emulsion containing polypeptides, the polypeptides which have different action principles and influence different metabolic pathways are compounded, so that an anti-wrinkle effect with quick effect, wide application spectrum andlasting effect is achieved. Based on the anti-wrinkle skin tightening emulsion containing the Chang 'e compound anti-wrinkle polypeptides, the test shows that the anti-wrinkle effect is obvious.