1473 results about "Ginsenoside" patented technology

The invention discloses an external skin care product capable of adjusting skin immunity and delaying skin aging. The external skin care product is characterized by comprising powder, an aqueous solution and emulsion, wherein the powder comprises oligopeptide-1 and ginsenoside; the aqueous solution comprises glycyrrhiza glabra root extract, artemisia capillaris flower extract, mulberry root extract, jujube fruit extract, scutellaria root extract, hydrolyzed rice protein and nicotinamide; and the emulsion comprises hgytantriol bifida ferment lysate, creatine, carnosine, alpha glucosyl hesperidin, hexapeptide-3, centella asiatica extract, coenzyme Q10 inclusion complex, opuntia ficus-indica stem extract, rhodiola rosea extract, saussurea involucrate extract, pseudo-ginseng root extract and Chinese angelica extract inclusion complex. According to the external skin care product, the powder, the aqueous solution and the emulsion are jointly used, and the external skin care product can reduce wrinkle and pachulosis, even skin tone and improve skin elasticity and skin firmness, so that the skin is finer and smoother and looks young.

The invention discloses a preparation method of a mushroom ferment beverage with effect of improving immunity, and belongs to the technical field of food beverages. According to the method disclosed by the invention, mushrooms and / or medicinal plants, fruit and ginseng are adopted as raw materials. The method comprises the following steps: slicing, chopping or crushing the raw materials; uniformly mixing the sliced, chopped or crushed raw materials so as to obtain a mixture; after adding sugar in the mixture, fermenting the mixture in ferment microorganisms; adding sugar when the sugar content is lowered; continuing fermentation so as to obtain the mushroom ferment beverage. According to the method disclosed by the invention, ferment bacteria can regulate intestinal flora and generate SOD (superoxide dismutase), so that the raw materials can be successfully fermented; the prepared ferment beverage contains protease, lipase, SOD, pectinase, lucid ganoderma, cauliflower fungus, pleurotus eryngii polysaccharide, rare ginsenoside, Rb2, C-K and the like. According to the method disclosed by the invention, the fermentation liquor and mycelium of the mushrooms can be directly used for fermentation; compared with sporophore, the raw materials are easier to obtain, and the method has the advantages of being short in fermentation cycle, easy in formula, simple in fermentation process, and the like.

The present invention relates to a medicine preparation with raw material comprising gen-seng, RADIX OPHIOPOGONIS and schizan drin and relates to the methods of preparing and quality control of the invention as well as relates to the quality control method of the raw material comprising gen-seng, radix ophiopogonis and schizan drin. The present invention comprises saponins content of gen-seng, amylase content of gen-seng, saponins content of radix ophiopogonis and neolignan content of schizan drin. Each unit dosage of preparation comprises Rg1 and Re for 0.08 mg-12 mg, polysaccharide of gen-seng for 1mg-460mg, general saponins for 5 mg-800 mg and Schisandrin for 0.036mg-6mg. a medicine functioning as cooperation can be or can not be added in the present invention which can be any acceptable medicine preparation type comprising oral taking solid preparation, oral taking semi-solid preparation, oral taking liquid preparation and injection. The present invention also provides the quality control method of gen-seng, RADIX OPHIOPOGONIS and schizan drin as well as the quality control method of the present invention.

A plant cultivation apparatus including: a guide rail disposed above a cultivation bed and extending along the length direction of the cultivation bed; a movable unit configured to move along the guide rail; an arm unit having a first end that is coupled to the movable unit, and a second end that is telescopically extendable from the movable unit toward the cultivation bed; and a UV radiation unit coupled to the second end of the arm unit and configured to irradiate the cultivation bed with a set amount of UV light.

The invention provides a panax ginseng adventitious root inducing culture medium and a method for inducing panax ginseng adventitious root. The panax ginseng adventitious root inducing culture mediumcomprises an MS basic culture medium, 0.2 mg / L-0.5 mg / L of IBA (indolebutyric acid), 2 mg / L-4 mg / L of NAA (naphthaleneacetic acid) and 20 g / L-30 g / L of sucrose. The panax ginseng adventitious root prepared by the method of the invention has a high content of ginsenoside, stable panax ginseng cell heredity and little influence by environmental factors, can be used as an ideal model for ginsenosidebiosynthesis molecule regulation research, and can be used for exploring an effective route for large-scale production of ginsenoside by engineered cells.

The invention relates to an action of ferulic acid on enhancing the drug effect of some medicaments and a purpose thereof, wherein the medicaments mainly comprise alkaloid medicaments including matrine, kushenin, sophocarpine, hyoscyamine, narceine, hanfangchin A, jamaicin, morphine, codeine, evodiamine, strychnine, catharanthine, vincristine, taxol, verticine, peimine, peiminine, ephedrine, pseudoephedrine, wilfordine, triptolide, tripdiolide and the like, and flavonoid medicaments including puerarin, ginsenoside, ginsengenin, mangiferin, scutelloside, alkannin, meletin, rutin, hesperidin, daidzin, soybean isoflavone, daidzein, carthamin, catechin and the like. The ferulic acid and the medicaments can form a compound or a medicament compound, or the ferulic acid and the medicaments can generate a chemical reaction (including salification, esterification, amidation, ketonization, etherification and the like), and / or the ferulic acid and the medicaments can generate a synergistic effect and an additive effect.

The present invention comprises compositions comprising essential oils, ginsenosides, and polysaccharides. The present invention comprises methods comprising sequential solvent extraction and polymer absorbent purification to obtain fractions comprising essential oils, ginsenosides, and polysaccharides. The compositions of the present invention may be used in forms such as tablets, gel caps, or fast-dissolve tablets for use as dietary supplements or pharmaceutical compositions. The compositions of the present invention may be used for treatment of cardiovascular diseases, neurodegenerative diseases, inflammatory diseases, hepatic disorders, viral diseases, and cancer.

The invention discloses a method for determining a radix notoginseng extract and contents of five types of ginsenosides in a preparation of the radix notoginseng extract by a Fourier transform near-infrared spectrograph. The method comprises the steps that a sample is detected by an ultra-high performance liquid chromatography, moving phase builds acetonitrile and water gradient elution parameters with separation degrees higher than 1.7 in chromatographic peaks of Rg1 and Re, and the spectrum preprocessing adopts the combination of 2 to 3 methods in Savitzky-Golay polynomial smoothing, second-order differential, Noriis derivative filtering and data normalization; and three preferred wave bands of the five types of ginsenosides are modeled, and a calibration model is built by any one of a partial least squares regression method, a principal component regression method and a multiple linear regression method. The method is used for determining the contents of the five types of ginsenosides in the sample to be detected, the determining result is consistent with a result determined by the ultra-high performance liquid chromatograph basically, the requirements of 'Chinese pharmacopoeia' are met, the accuracy is high, and the determination speed is increased substantially.

The invention discloses blank mixed micelle, and a preparation method and applications thereof. The blank mixed micelle comprises an amphiphilic copolymer and ginsenoside represented by formula I, ishigh in efficiency, is safe, is stable, is high in targeting performance, is excellent in homogeneity, is stable in quality, is convention in preparation technology, can be used for coating one or a plurality of active substances in drugs or cosmetics and health care substances, and is capable of forming mixed micelle containing loaded active substances. Compared with conventional nanometer micelle, the blank mixed micelle possesses following advantages: the mixed micelle loaded with active substances is excellent in drug forming performance, multiple drug resistance, stability, homogeneity, and safety performance, and is small in particle size; and the curative effect of loaded active drugs on drug resistant cells is better.

The invention relates to a compound immunopotentiator for post larvae of litopenaeus vannamei, which comprises the following components in percentage by weight: 20-30 percent of beta-glucan, 20-30 percent of chitosan, 5-10 percent of ginsenoside, 10-20 percent of astragalus polysaccharides, 5-10 percent of phospholipid, 40-60 percent of vitamin C-2-polyphosphate ester, 10-15 percent of vitamin E, 5-10 percent of vitamin A, 10-20 percent of bacillus subtilis and 1-5 percent of clamworm powder. The invention has the following advantages that: (1) the problem of feedback inhibition of the post larvae of litopenaeus vannamei is overcome effectively; (2) the immunity of the post larvae of litopenaeus vannamei is enhanced obviously, and the survival rate is increased; (3) the activity and the growth speed of the post larvae of litopenaeus vannamei are increased obviously; (4) the compound immunopotentiator has the addition amount of only 0.2-0.3% when used as a feed additive for a particle feed of the post larvae of litopenaeus vannamei; (5) no adverse effect on the palatability of the feed exists; and (6) the source of the raw materials is stable, the cost is low, and the production process is simple.

The invention discloses ginseng nutrient enriched rice and a preparation method thereof, and belongs to the field of food processing. The method is characterized by: dissolving total ginsenoside and pectin through distilled water to prepare a mixing nutrient solution, then carrying out a first spraying to rice; dissolving vitamin B1, vitamin B2 and L-lysine hydrochloride through the distilled water to prepare a mixing nutrient solution, then carrying out a second spraying to the rice; finally spraying protection film prepared from zein to the rice to prepare the ginseng nutrient enriched rice. According to the preparation method provided by the present invention, the total ginsenoside component can be maintained well, such that loss of the total ginsenoside component due to rice washing is reduced.

The invention relates to the application of 20(R)-ginsenoside-Rg3 in the preparing process of medicine for treating or preventing hypertension, in preparing medicine for treating or preventing myocardial ischemia, and in preparing medicament for prevention or treatment of heart failure.

The invention provides a method for preparing a ginseng and coix seed mixture and a ginseng and coix seed paste. Raw materials comprise 1 to 10 parts of ginseng, 10 to 30 parts of coix seed, 2 to 10 parts of lotus seed, 10 to 35 parts of glutinous rice, 5 to 20 parts of black rice, 10 to 30 parts of flour, 2 to 15 parts of black sesame, 1 to 6 parts of walnut kernel, 1 to 10 parts of peanut kernel, 3 to 10 parts of malto dextrin, 1 to 4 parts of black soya bean, 1 to 4 parts of small red bean, 1 to 10 parts of edible modified starch and 2 to 10 parts of white granulated sugar. The ginseng is subjected to supercritical CO2 extraction, the green production process is really realized, and the total extraction rate of active substances such as ginsenoside and the like is over 90 percent. The obtained product is fine powder without cakes, is easy to store and convenient to use, has characteristics of fine and smooth texture, delicious taste and tasty mouthfeel, cleanness and faint scent, and high digestion and absorption rate of natural nutrients, and maintains natural nutrient components of the raw materials, and improves the mouthfeel and the nutrient component absorption rate.

The present invention relates to a group of glycosyl transferase and applications thereof, and specifically provides applications of the glycosyl transferase gGT29-7 and a derived polypeptide thereof in terpene compound glycosylation catalysis and new saponin synthesis, wherein the glycosyl transferase can specifically and efficiently transfer the glycosyl from a glycosyl donor to the first glycosyl on C-3 site and / or C-6 site of a tetracyclic triterpene compound so as to extend the sugar chain. The glycosyl transferase of the present invention can further be used for constructing artificial ly-synthesized rare ginsenosides and a variety of new ginsenosides and derivatives thereof.

The invention discloses a gene promoter of ginseng PgPDR3 responded by methyl jasmonate and an application thereof. The sequences of the gene promoter of the ginseng PgPDR3 are shown in SEQ ID NO.1, or are the DNA sequences of which the homology with SEQ ID NO.1 is over 99%. According to the invention, a Genomewalker technology is adopted to clone, later the sequences of the gene promoter of the PDR transport protein is obtained, and then the expression vector Pcambia1301-ProPDR3::GUS of the promoter is built; if the promoter in the transgenic tobacco drives the GUS to express, and can be controlled by ginsenoside, salicylic acid, gibberellins and abscisic acid, the promoter participates in the transport and accumulation of the ginsenoside, which provides a basis for cloning the gene of key control recording factor in the ginsenoside transport signal pathway and controlling the transport and accumulation of the terpenoid, such as ginsenoside; and fine plants containing rich ginsenoside can be obtained by using a method for controlling or improving the ginseng and other plants via the promoter or the derivative thereof.

The present invention provides compositions and methods for treating and preventing Alzheimer's disease by administering to a subject an effective amount of a dammarane or ginsenoside compound. The invention also provides compositions and methods for modulating beta-amyloid protein production, including Abeta42 in a cell. The invention further provides compositions and methods for treating and preventing neurodegeneration by administering to a subject an effective amount of a dammarane or ginsenoside compound. Additionally, the invention provides kits for use in treating and / or preventing Alzheimer's disease and neurodegeneration, as well as for reducing the production of beta-amyloid protein.

The invention relates to a group of glycosyl transferases and applications of the glycosyl transferases. Particularly, the invention provides applications of glycosyl transferases gGT25, gGT13, gGT30, gGT25-1, gGT25-3, gGT25-5, gGT29, gGT29-3, gGT29-4, gGT29-5, gGT29-6, gGT29-7, 3GT1, 3GT2, 3GT3 and 3GT4, and derived peptides of the glycosyl transferases in glycosylation catalysis and new saponin synthesis of terpenoids. The glycosyl transferases can specifically and efficiently catalyze hydroxyl glycosylation of C-20 bit and / or C-6 bit and / or C-3 of a tetracyclic triterpenoid compound substrate, and / or transfers the glycosyl groups from glycosyl donors to the first glycosyl groups of the C-3 bit and C-6 bit of the tetracyclic triterpenoid compound to extend a carbohydrate chain. The glycosyl transferases disclosed by the invention can also be applied to building synthetic rare ginsenosides and a plurality of novel ginsenosides and derivatives of the ginsenosides.

The invention belongs to the technical field of bean sprout production and specially discloses a functional bean sprout and a production method thereof. The method comprises the following steps: 1, adding water or alcohol to 30-65wt.% of folium cortex eucommiae, 15-30wt.% of ginseng roots and 15-40wt.% of ginkgo leaves for extracting, filtering, adding vitamin C to a filtrate, wherein the weight of the vitamin C is 0.01-0.02% of the weight of the filtrate, and adjusting the pH value of the liquid to 4.5-7.0 by using edible acid, thereby obtaining sprout-cultivating liquid, and 2, soaking bean seeds in the sprout-cultivating liquid, spraying with the sprout-cultivating liquid and / or water, and cultivating according to a conventional bean sprout cultivating method, thereby obtaining the bean sprout. Through the implementation of the production method, the folium cortex eucommiae, the ginseng roots and the ginkgo leaves are effectively utilized, a new method for compressively utilizing the traditional Chinese medicine is supplied, the prepared functional bean sprout contains the active ingredients, such as ginsenoside, which are beneficial to the health of human body, and an effective method and a research thought are supplied for developing the functional bean sprout.

The invention discloses a PDR transport protein gene promoter for controlling ginsenoside accumulation, and its application. A promoter ProPDR1 has a DNA sequence represented by SEQIDNo.1 or has a DNA sequence having a homology of above 99% to SEQIDNo.1. A PgPDR1 transport protein gene promoter sequence is obtained through cloning by adopting genome walker in the invention, and includes a TCA element and TCCACCT-Motif. A promoter expression vector pBI121-ProPDR1::GUS is constructed in the invention, and reporter gene GUS is strongly controlled by ginsenoside, salicylic acid, methyl jasmonate and abscisic acid in transgenic tobacco under the driving of the promoter ProPDR1, so the ginseng PgPDR1 gene expression promoted by the promoter is closely related to the ginsenoside accumulation. The promoter provided by the invention has very important application values in the medical plant secondary metabolite synthesis and accumulation control gene engineering.

The invention relates to an application method of an elicitor in the hairy root of American ginseng, belonging to the field of crop biotechnology. The process comprises the following steps: (1) induction of the hairy root of American ginseng; (2) measurement of the growth dynamic and ginsenoside content of the asexual system of the hairy root of American ginseng; (3) optimization of culture conditions for the hairy root of American ginseng; (4) preparation of an elicitor; (5) regulation of enzyme activity in a metabolic pathway. In the method provided by the invention, the combination of the culture conditions for the hairy root of American ginseng is put forward, the influence of two elicitors, namely salicylic acid and methyl jasmonate, on the metabolism of American ginseng is studied in order to increase the saponin output, a basis is provided for large-scale production of American ginseng saponin, and a foundation is laid for realizing industrial production of American ginseng saponin so as to meet the ever-increasing needs of people.

The invention relates to the fields of organic synthesis and pharmacochemistry, particularly (20S,24S)-ocotillol ginsenoside derivatives, of which the structure is disclosed as general formula (I). The invention also discloses a preparation method of the (20S,24S)-ocotillol ginsenoside derivatives, a pharmaceutical composition containing the (20S,24S)-ocotillol ginsenoside derivatives, and application of the (20S,24S)-ocotillol ginsenoside derivatives in bacterial infection disease inhibition. General formula (I).

The invention provides a steam-explosion combined bio-composite enzyme preparation, and a method for producing ginsenoside by using ginseng, American ginseng, ginseng stems and leaves, American ginseng stems and leaves and the like as raw materials. Compared with a conventional method, the method has the characteristics of high yield of ginseoside extract, high content of extract saponin, high extraction rate of gnsenoside and the like.

The invention provides an enzyme method for extracting ginsenoside and an obtained ginsenoside extractive. The method comprises the steps of carrying out enzyme extraction and alcohol extraction on vegetable drug ginseng, wherein the enzyme extraction step is as follows: an aqueous solution with an enzyme preparation is taken as an enzyme extracting solution, the smashed or sliced ginseng is steeped and extracted, the enzyme preparation is cellulase, pectinase or a mixture of the cellulase and the pectinase, and enzymatic hydrolysis is carried out for 0.5-6 hours at 30-50 DEG C in an extraction process; the alcohol extraction step is as follows: alcohol is added to a ginseng solution subjected to enzymatic hydrolysis for preparing an alcohol extract with 30%-60% of volume concentration, and heating reflux is carried out for 2 hours to 10 hours at 50 DEG C-90 DEG C; and residues are refluxed and extracted again by using alcohol with the same concentration for 1-4 hours, and extracting solutions are combined. The ginsenoside extractive obtained by the method has high content of effective components; and the extraction rate is increased by above 30% relative to that of simple alcohol heating reflux. The method has the advantages of mild extraction conditions, operation simplicity and low cost.

The present invention relates to a kind of medicine preparation with ginseng component and aconite root component and its preparation process and quality control method. Of the medicine preparation, each unit contains total ginsenoside in 1-90 mg, total ginseng polysaccharide in 2-282 mg, and total aconite root alkaloid in 0.02-22 mg. The medicine preparation may have other synergistic medicine component added. Its preparation process includes extracting the total ginsenoside, the total ginseng polysaccharide and the total aconite root alkaloid; adding supplementary material; and forming different preparation forms.

The invention provides infant brewing powder prepared from brown rice and millet through mixing in proportion. The infant brewing powder is prepared from the components as follows: brown rice, bananas, rhizoma dioscoreae, table salt, blueberries, maltodextrin, pumpkins, carrots, mint powder, ginsenoside and millet. The infant brewing powder prepared from brown rice and millet through mixing in proportion takes the brown rice and millet are main raw materials, and the brown rice contains richer vitamins, minerals and dietary fibers as compared with common refined rice; the millet is edible and has the effects of clearing heat, arresting thirsty, nourishing yin, tonifying the spleen, kidney, intestines and stomach, inducing urination, treating water diarrhea and the like after being added to medicines; the blue berries and the ginsenoside both have very high nutritional value, but the nutrition can be lost easily due to the poor processing effect, in order to protect the nutritional value from loss, the maltodextrin is added to protect the two raw materials, and the finally obtained infant brewing powder has the significant effect on improving the motor function of infants.

The invention relates to a method for preparing raw materials containing rare ginsenoside Rg3, Rh2 and the like for medicines, foods and healthcare products through process steps of wetting, steam explosion and the like of an acid reagent by taking ginseng, American ginseng, ginseng stem leaves and ginseng stem leaves as raw materials. The method disclosed by the invention has advanced process and is simple and feasible, the products prepared by the method disclosed by the invention contain the rare ginsenoside Rg3, Rh2 and the like, and the leaching rate of effective elements is high, the leaching is rapid, and effective elements are easy to be absorbed by human bodies. The products can be applied to the medicines, the foods and the healthcare products directly or after being simply processed.

A process for preparing the malonyl ginsenoside used to prepare the medicine for treating diabetes includes pulverizing fresh ginseng, immersing in alcohol for extracting, vacuum recovering of solvent, concentrating to become aqueous solution, repeated extraction by n-butanol and water, concentrating, adsorbing by macroreticular resin column, eluting with alcohol, and recovering alcohol. A monoacyl arasaponin-R4 malonate and its medical application are also disclosed.

The present invention relates to external liquid and solid kreotoxin (argireline) composite nanometer latex for skin and a preparation method thereof. The weight proportion of each raw material of liquid nanometer latex is 10g of isopropyl myristate, 2g of vitamin E, 0.8g of vitelline lecithin, 0.2g of ginseng saponin, 0.01g of rhodiola element, 0.005g of the argireline, 0.001g of superoxide dismutase, 0.5g of reduction type glutathione, 5g of fetal calf serum, 0.05g of hyaluronic acid, 0.05g of ceramide, 40g of distilled water, 36g of polyethylene glyceride glycol caprylic decanoate and 12g of polyglycerol fatty acid ester; the weight proportion of each raw material of solid nanometer latex is 10g of the isopropyl myristate, 2g of the vitamin E, 0.8g of the vitelline lecithin, 0.2g of the ginseng saponin, 0.01g of the rhodiola element, 0.005g of the argireline, 0.001g of the superoxide dismutase, 0.5g of the reduction type glutathione, 5g of the fetal calf serum, 0.05g of the hyaluronic acid, 0.05g of the ceramide, 40g of the distilled water, 36g of the polyethylene glyceride glycol caprylic decanoate, 12g of the polyglycerol fatty acid ester, 22g of mannitol and 3g of glycin.