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1472 results about "Ginsenoside" patented technology

Ginsenosides or panaxosides are a class of natural product steroid glycosides and triterpene saponins. Compounds in this family are found almost exclusively in the plant genus Panax (ginseng), which has a long history of use in traditional medicine that has led to the study of pharmacological effects of ginseng compounds. As a class, ginsenosides exhibit a large variety of subtle and difficult-to-characterize biological effects when studied in isolation.

Preparation method of mushroom ferment beverage with effect of improving immunity

The invention discloses a preparation method of a mushroom ferment beverage with effect of improving immunity, and belongs to the technical field of food beverages. According to the method disclosed by the invention, mushrooms and / or medicinal plants, fruit and ginseng are adopted as raw materials. The method comprises the following steps: slicing, chopping or crushing the raw materials; uniformly mixing the sliced, chopped or crushed raw materials so as to obtain a mixture; after adding sugar in the mixture, fermenting the mixture in ferment microorganisms; adding sugar when the sugar content is lowered; continuing fermentation so as to obtain the mushroom ferment beverage. According to the method disclosed by the invention, ferment bacteria can regulate intestinal flora and generate SOD (superoxide dismutase), so that the raw materials can be successfully fermented; the prepared ferment beverage contains protease, lipase, SOD, pectinase, lucid ganoderma, cauliflower fungus, pleurotus eryngii polysaccharide, rare ginsenoside, Rb2, C-K and the like. According to the method disclosed by the invention, the fermentation liquor and mycelium of the mushrooms can be directly used for fermentation; compared with sporophore, the raw materials are easier to obtain, and the method has the advantages of being short in fermentation cycle, easy in formula, simple in fermentation process, and the like.
Owner:JIANGNAN UNIV +1

Pharmaceutical formulations with the raw material containing panax, ophiopogon root and schisandra fruit, processes for their preparation, the raw material and the quality control method for the prepa

The present invention relates to a medicine preparation with raw material comprising gen-seng, RADIX OPHIOPOGONIS and schizan drin and relates to the methods of preparing and quality control of the invention as well as relates to the quality control method of the raw material comprising gen-seng, radix ophiopogonis and schizan drin. The present invention comprises saponins content of gen-seng, amylase content of gen-seng, saponins content of radix ophiopogonis and neolignan content of schizan drin. Each unit dosage of preparation comprises Rg1 and Re for 0.08 mg-12 mg, polysaccharide of gen-seng for 1mg-460mg, general saponins for 5 mg-800 mg and Schisandrin for 0.036mg-6mg. a medicine functioning as cooperation can be or can not be added in the present invention which can be any acceptable medicine preparation type comprising oral taking solid preparation, oral taking semi-solid preparation, oral taking liquid preparation and injection. The present invention also provides the quality control method of gen-seng, RADIX OPHIOPOGONIS and schizan drin as well as the quality control method of the present invention.
Owner:天津市轩宏医药技术有限公司 +1

Method for determining radix notoginseng extract and contents of five types of ginsenosides in preparation of radix notoginseng extract by Fourier transform near-infrared spectrograph

The invention discloses a method for determining a radix notoginseng extract and contents of five types of ginsenosides in a preparation of the radix notoginseng extract by a Fourier transform near-infrared spectrograph. The method comprises the steps that a sample is detected by an ultra-high performance liquid chromatography, moving phase builds acetonitrile and water gradient elution parameters with separation degrees higher than 1.7 in chromatographic peaks of Rg1 and Re, and the spectrum preprocessing adopts the combination of 2 to 3 methods in Savitzky-Golay polynomial smoothing, second-order differential, Noriis derivative filtering and data normalization; and three preferred wave bands of the five types of ginsenosides are modeled, and a calibration model is built by any one of a partial least squares regression method, a principal component regression method and a multiple linear regression method. The method is used for determining the contents of the five types of ginsenosides in the sample to be detected, the determining result is consistent with a result determined by the ultra-high performance liquid chromatograph basically, the requirements of 'Chinese pharmacopoeia' are met, the accuracy is high, and the determination speed is increased substantially.
Owner:YUNNAN PHYTOPHARML

Glycosyl transferases and applications of glycosyl transferases

ActiveCN104232723ASpecific and efficient transferHas anticancer activityTransferasesFermentationTriterpeneCoa transferase
The invention relates to a group of glycosyl transferases and applications of the glycosyl transferases. Particularly, the invention provides applications of glycosyl transferases gGT25, gGT13, gGT30, gGT25-1, gGT25-3, gGT25-5, gGT29, gGT29-3, gGT29-4, gGT29-5, gGT29-6, gGT29-7, 3GT1, 3GT2, 3GT3 and 3GT4, and derived peptides of the glycosyl transferases in glycosylation catalysis and new saponin synthesis of terpenoids. The glycosyl transferases can specifically and efficiently catalyze hydroxyl glycosylation of C-20 bit and / or C-6 bit and / or C-3 of a tetracyclic triterpenoid compound substrate, and / or transfers the glycosyl groups from glycosyl donors to the first glycosyl groups of the C-3 bit and C-6 bit of the tetracyclic triterpenoid compound to extend a carbohydrate chain. The glycosyl transferases disclosed by the invention can also be applied to building synthetic rare ginsenosides and a plurality of novel ginsenosides and derivatives of the ginsenosides.
Owner:SYNBIOTECH (SUZHOU) CO LTD

(20S,24S)-ocotillol ginsenoside derivatives with antibacterial activity, and preparation method and application thereof

The invention relates to the fields of organic synthesis and pharmacochemistry, particularly (20S,24S)-ocotillol ginsenoside derivatives, of which the structure is disclosed as general formula (I). The invention also discloses a preparation method of the (20S,24S)-ocotillol ginsenoside derivatives, a pharmaceutical composition containing the (20S,24S)-ocotillol ginsenoside derivatives, and application of the (20S,24S)-ocotillol ginsenoside derivatives in bacterial infection disease inhibition. General formula (I).
Owner:CHINA PHARM UNIV

Enzyme method for extracting ginsenoside and obtained ginsenoside extractive

The invention provides an enzyme method for extracting ginsenoside and an obtained ginsenoside extractive. The method comprises the steps of carrying out enzyme extraction and alcohol extraction on vegetable drug ginseng, wherein the enzyme extraction step is as follows: an aqueous solution with an enzyme preparation is taken as an enzyme extracting solution, the smashed or sliced ginseng is steeped and extracted, the enzyme preparation is cellulase, pectinase or a mixture of the cellulase and the pectinase, and enzymatic hydrolysis is carried out for 0.5-6 hours at 30-50 DEG C in an extraction process; the alcohol extraction step is as follows: alcohol is added to a ginseng solution subjected to enzymatic hydrolysis for preparing an alcohol extract with 30%-60% of volume concentration, and heating reflux is carried out for 2 hours to 10 hours at 50 DEG C-90 DEG C; and residues are refluxed and extracted again by using alcohol with the same concentration for 1-4 hours, and extracting solutions are combined. The ginsenoside extractive obtained by the method has high content of effective components; and the extraction rate is increased by above 30% relative to that of simple alcohol heating reflux. The method has the advantages of mild extraction conditions, operation simplicity and low cost.
Owner:安徽丰润生物技术股份有限公司 +1

Method for increasing content of rare saponin in ginseng raw material by explosion of steam

The invention relates to a method for preparing raw materials containing rare ginsenoside Rg3, Rh2 and the like for medicines, foods and healthcare products through process steps of wetting, steam explosion and the like of an acid reagent by taking ginseng, American ginseng, ginseng stem leaves and ginseng stem leaves as raw materials. The method disclosed by the invention has advanced process and is simple and feasible, the products prepared by the method disclosed by the invention contain the rare ginsenoside Rg3, Rh2 and the like, and the leaching rate of effective elements is high, the leaching is rapid, and effective elements are easy to be absorbed by human bodies. The products can be applied to the medicines, the foods and the healthcare products directly or after being simply processed.
Owner:JILIN AGRICULTURAL UNIV
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