The invention discloses a formula of children' s
antipyretic granule by using
radix bupleuri and
cassia twig, and its preparation method, and belongs to the technical field of
traditional Chinese medicine. The invention mainly solves the problems of bad mouth feel, easily bacterial infection and inconvenient taking in low temperature season of the present oral liquid. The children' s
antipyretic granule comprises the following bulk drugs in the granular: 200-300 parts of
radix bupleuri; 70-110 parts of
cassia twig, 200-300 parts of kudzuvine root; 100-150 parts of radix scutellariae, 100-150 parts of
honeysuckle flower, 100-300 parts of
isatis root and 70-110 parts of
periostracum cicadae. The method comprises the following steps: crushing
cassia twig,
radix bupleuri and
honeysuckle flower, distilling,
salting out, refrigerating and respectively taking
essential oil, adding beta-cyclodextrins; extracting kudzuvine root by an
ethanol percolation method to obtain a
flavonoid component; performing processes of
water extraction, acid
precipitation and
alcohol precipitation to radix scutellariae to obtain high content
scutelloside; decocting the other medicinal materials and concentrating to produce a thin paste; mixing each extract and concentrating to a thick paste, adding a proper amount of
cane sugar, beta- cyclodextrins clathrate and a proper amount of
dextrin to obtain the granule. The invention has the functions of sweating and relieving exterior syndrome as well as clearing heat and detoxifying, and has the advantages of good mouth feel, less loss of effective ingredients, stable quality, safe auxiliary materials and convenient administration, the children' s
antipyretic granule by using radix bupleuri and cassia twig is mainly used for treating children's exogenousfever illness.