47 results about "Scutelloside" patented technology

The invention relates to a traditional Chinese medicine anti-allergic skin-wetting lipstick and a preparation method thereof. The invention is characterized in that the component materials and the weight portions are as follows: 0.01 to 10 portions of scutelloside, 1 to 20 portions of redroot gromwell root, 20 to 100 portions of oiliness, 10 to 40 portions of waxiness, 0.2 to 2 portions of suspending agent and 0.01 to 5 portions of preservative. The invention has the characteristics as follows: the lipstick adopts traditional Chinese medicine as active ingredients, has no pigment, little irritation, low toxicity, good compatibility, allergy free and skin wetness, can be used for preventing chronic cheilitis and improving beautiful appearance of lip and simultaneously has assisted effect to chronic cheilitis. Particularly, the preparation method adopts nanotechnology to lead the effects of the lipstick of preventing allergy, wetting the skin and having assisted effect to chronic cheilitis to be better.

The invention discloses a method for extracting scutelloside and scutellarin from baikal skullcap root. The method comprises the following steps of: (1) performing ultrasonic extraction on a solvent; (2) adsorbing Fe3O4 magnetic nanoparticles; and (3) performing desorption. The method is simple and rapid; separation of an absorption carrier and a feed liquid can be realized by additionally applying a magnetic field; scutelloside and scutellarin can be eluted selectively through different eluents, so that loss of raw materials and energy consumption is avoided, and cost is reduced effectively; and Fe3O4 magnetic nanoparticles can be used circularly, so that cost can be saved effectively.

The invention relates to an antivirulent drug composition, and a preparation and a preparation method thereof. The drug composition comprises scutelloside, chlorogenic acid and caffeic acid, and phillyrin, wherein the weight ratio of scutelloside to chlorogenic acid to caffeic acid to phillyrin is (10-18):(0.6-2):(0.3-1). The drug composition and the preparation provided by the invention have a better inhibition effect on avian influenza virus and influenza A H1N1, with the effect being superior to that in the prior art.

An anti-anaphylactic condom features that it contains the anti-anaphylactic components including scutelloside, matrine, glycyrrhizin and thiapolyphenol. Its preparing process is also disclosed.

The invention discloses a cultivation method for inducing scutellaria baicalensis hairy root based on agrobacterium rhizogenes infection, which uses an agrobacterium rhizogenes bacteria liquid to infect root of a scutellaria baicalensis explant and induces the scutellaria baicalensis explant to form a hairy root, the scutellaria baicalensis hairy root presents yellow hairy on a MS solid medium, so that scutelloside can be stably synthesized, an ITS sequencing is performed and the hairy root can be identified as the scutellaria baicalensis hairy root of a scutellaria. Then seed selection is performed for further in a seed selection medium and a cultivation condition can be optimized to select lines which raise the content of active ingredient scutelloside used for hairy root traditional Chinese medicines. Hairy root can be obtained through scutellaria of a scutellaria introduced by agrobacterium rhizogenes, wherein the inductivity can reach 10 - 40%, the obtained scutellaria baicalensis hairy root presents yellow hairy which is capable of stably synthesizing scutelloside. According to the invention, the scutellaria baicalensis hairy root of a scutellaria is cultivated on the optimized medium, the growth is rapid and the biomass can be increased for 23 -35 times in 30 - 35 days, and the cultivation is performed under the dark conditions. The invention has the characteristics of low energy consumption and low cost, which is suitable for industrialization production.

The invention discloses a traditional Chinese medicine extract mixed preparation which comprises a baical skullcap root extract, a cape jasmine fruit extract and an Indian buead extract, wherein the mixture ratio of the three is (80-100): (80-100): (100-150); and the content of scutelloside in the baical skullcap root extract is above 90%, the content of geniposide in the cape jasmine fruit extract is above 90%, and the content of polysaccharides in the Indian buead extract is above 50%. The traditional Chinese medicine extract mixed preparation has the effects of protecting liver and benefiting gallbladder, and can be used for preparing medicaments or health care products for protecting the liver and benefiting the gallbladder, or the medicaments for treating obstructive jaundice, or the medicament for treating cholestasis, or the medicaments for treating chronic alcoholic liver injury. The effects of the traditional Chinese medicine extract mixed preparation for and benefiting the gallbladder and protecting the cholestasis of rats caused by bile duct ligation and ANIT (alpha-naphthylisothiocyanate) and the alcoholic liver injury of the rats are obviously better than conventional control medicaments, and the liver injury degree and the icterus index can be significantly reduced.

A quality control method for the Chinese medicine í‹Antihypertenssive Duzhong medicineíŒ to treat hypertension includes such steps as examining its characteristics, identifying scutellaria root, uncaria stem with hooks and motherwort, and measuring the content of scutelloside.

The invention discloses a quality control method for Niuhuang Ninggong tablet. The method comprises the following steps: morphological identification, histological and thin layer chromatography identification, arsenic trioxide detection, content measurement. The content of Baikal skullcap root in form of scutelloside in each tablet is no less than 0.8 mg, preferably no less than 1.0 mg, and most preferably no less than 1.1mg. The invention optimizes the prior examination method, establishes new examination method, ensures the reliability and uniformity of product quality and further improves the safety of products.

The invention relates to a compound qinlan oral liquid which includes an extractor from honeysuckle, forsythia, radix isatidis and radix scutellariae. A method for preparing the oral liquid includes steps as follows: extracting radix scutellariae by using method of acid precipitation; processing combining decocting to honeysuckle, forsythia and radix isatidis; combining the extract of above component, adding suitable assistant material after cooling processing, adding water and boiling, then adjusting PH value to 6.8-7.2, filtering, filling and sterilizing, finially obtaining the compound qinlan oral liquid. The preparing method can increase transfer rate of scutelloside, accordingly, increase scutelloside content in the preparation. The compound qinlan oral liquid has more stable quality.

A Chinese medicine 'Xuemingmu' for treating eyeground hemorrhage is disclosed. Its quality test method features that the scutelloside, emodin, chrysophanol and protocatechuic aldehyde are qualitatively discriminated, and the content of danshensu is measured by high-effect liquid-phase chromatography.

A quality control method for the compound Hongcao medicine in the form of freeze-dried powder injection, injection, or orally taken medicine features that an efficient liquid-phase chromatography is used to measure the contents of scutelloside, isoorientin and orientin.

The invention relates to a pharmaceutical composition and a preparation method. The pharmaceutical composition comprises the following raw materials by weight: 1-4 parts of cholic acid, 1-4 parts of scutelloside, 0.5-2 parts of tripterygium glycosides, 2-7 parts of cape jasmine and 0.5-5 parts of cornu bubali, and the raw materials are cooperated with other auxiliary materials to prepare a medicine. The pharmaceutical composition has the advantages that the pharmaceutical composition has same curative effect with a Qingkailing compound for preventing and treating uveitis, intraocular inflammation and immunological eye diseases, The pharmaceutical composition takes a holism concept of a traditional Chinese medicine as a base, by adjusting the equilibrium between yin and yang of human body, the pharmaceutical composition can reach the effects for resisting inflammation, increasing immunity, reducing recurrence rate, increasing cure rate and improving the vision function of patients.

The invention discloses a plant flavone essence cigarette bead for a cigarette, and a preparation method and application thereof. The preparation method comprises the following steps: weighing an adhesive accounting for 0.1 to 1% of the weight of plant flavone essence; dissolving the adhesive with water and then adding dissolved adhesive into the plant flavone essence; extruding the obtained mixture with an extruder to obtain an elongated strip-like mixture; then rounding the mixture with a rounding machine; and carrying out drying so as to obtain the plant flavone essence cigarette bead. The plant flavone essence comprises, by weight, 20 to 60% of luteolin, 20 to 60% of scutelloside, 10 to 30% of kaempferol and 10 to 30% of naringin. The plant flavone essence cigarette bead has excellent natural smell and brings comfortable aromatic smell to a cigarette; when one smokes the cigarette, aroma components capable of improving aroma quantity and aroma quality are given out by substances in the cigarette bead through pyrolysis after combustion; and active components in the plant flavone essence cigarette bead enter the oral cavity of the human body with smoke in the cigarette, can directly act on the throat and exert good effect on improving comfortableness of the throat.

A composite medicine in the form of solution for treating cardiovascular and cerebrovascular diseases features that it contains high-purity wild-scutelloside and pH regulator proportionally and the content of said high-purity wild-scutelloside can be stabilized for at least 18 months.

An Yinhuang softgel features that its active components in its core are the volatile oil and chlorogenic acid extracted from honeysuckle flower and the scutelloside extracted from scutellaria root. Its preparing process is also disclosed.

The invention discloses a scutelloside colon targeted medicine preparation, which comprises scutelloside and cyclodextrin inclusion compounds, natural polysaccharide colon targeted materials and enteric coating materials at a specific proportion. Meanwhile, the invention also discloses a preparation method of the scutelloside colon targeted medicine preparation. The method comprises the following steps that scutelloside and cyclodextrin are proportionally prepared into the scutelloside and cyclodextrin inclusion compounds; the scutelloside and cyclodextrin inclusion compounds and the natural polysaccharide colon targeted materials are proportionally crosslinked and solidified; filtering, washing and drying are performed; scutelloside colon targeted protomeres are obtained; the scutelloside colon targeted protomeres are coated by a solution of the enteric coating materials, and the scutelloside colon targeted medicine preparation is obtained. The scutelloside colon targeted medicine preparation is invented by a specific method; the defect of low water solubility of the scutelloside is overcome; medicine can be located and released in the colon position; a colon targeted goal is achieved; the process is simple; the popularization and the application are easy.

An application of wild-scutelloside and wild-scutellaglucone in preparing the antineoplastic medicines is disclosed.

The invention discloses a formula of children' s antipyretic granule by using radix bupleuri and cassia twig, and its preparation method, and belongs to the technical field of traditional Chinese medicine. The invention mainly solves the problems of bad mouth feel, easily bacterial infection and inconvenient taking in low temperature season of the present oral liquid. The children' s antipyretic granule comprises the following bulk drugs in the granular: 200-300 parts of radix bupleuri; 70-110 parts of cassia twig, 200-300 parts of kudzuvine root; 100-150 parts of radix scutellariae, 100-150 parts of honeysuckle flower, 100-300 parts of isatis root and 70-110 parts of periostracum cicadae. The method comprises the following steps: crushing cassia twig, radix bupleuri and honeysuckle flower, distilling, salting out, refrigerating and respectively taking essential oil, adding beta-cyclodextrins; extracting kudzuvine root by an ethanol percolation method to obtain a flavonoid component; performing processes of water extraction, acid precipitation and alcohol precipitation to radix scutellariae to obtain high content scutelloside; decocting the other medicinal materials and concentrating to produce a thin paste; mixing each extract and concentrating to a thick paste, adding a proper amount of cane sugar, beta- cyclodextrins clathrate and a proper amount of dextrin to obtain the granule. The invention has the functions of sweating and relieving exterior syndrome as well as clearing heat and detoxifying, and has the advantages of good mouth feel, less loss of effective ingredients, stable quality, safe auxiliary materials and convenient administration, the children' s antipyretic granule by using radix bupleuri and cassia twig is mainly used for treating children's exogenousfever illness.

An application of scutelloside along with a Pt-type chemicotherapeutic medicine including carboplatin and taxol in preparing the medicine for treating tumor is disclosed. A resultant composite medicine is also disclosed.

A composite medicine in the form of solution for treating cardiovascular and cerebrovascular diseases features that it contains high-purity wild-scutelloside and pH regulator proportionally and the content of said high-purity wild-scutelloside can be stabilized for at least 18 months.

The invention relates to a honeysuckle flower composition feed additive for pigs. The additive is formed by 40-70 parts of honeysuckle flower extract, 5-20 parts of radix bupleuri extract, 5-20 parts of Radix Scutellariae, 5-20 parts of Herba Taraxaci extract and 20-30 parts of licorice root extract. The granularity of the additive is 300-400 meshes, the appearance of the additive is yellow to brown-yellow powder, and the effective components of the additive comprise 5-20% of chlorogenic acid, 5-10% of scutelloside and 15-25% of glycyrrhizic acid; and when the additive is used, 0.05-0.5% of the additive is mixed with a feed, and the obtained feed is used to feed pigs. The additive can prevent and treat porcine highly pathogenic porcine reproductive and respiratory syndrome, porcine rotavirus disease, influenza, infectious bronchitis and viral diseases induced by porcine circovirus, small circovirus and foot and mouth disease viruses, and can effectively promote growth of live pigs.

The invention discloses a cultivation method for inducing scutellaria baicalensis hairy root based on agrobacterium rhizogenes infection, which uses an agrobacterium rhizogenes bacteria liquid to infect root of a scutellaria baicalensis explant and induces the scutellaria baicalensis explant to form a hairy root, the scutellaria baicalensis hairy root presents yellow hairy on a MS solid medium, so that scutelloside can be stably synthesized, an ITS sequencing is performed and the hairy root can be identified as the scutellaria baicalensis hairy root of a scutellaria. Then seed selection is performed for further in a seed selection medium and a cultivation condition can be optimized to select lines which raise the content of active ingredient scutelloside used for hairy root traditional Chinese medicines. Hairy root can be obtained through scutellaria of a scutellaria introduced by agrobacterium rhizogenes, wherein the inductivity can reach 10 - 40%, the obtained scutellaria baicalensis hairy root presents yellow hairy which is capable of stably synthesizing scutelloside. According to the invention, the scutellaria baicalensis hairy root of a scutellaria is cultivated on the optimized medium, the growth is rapid and the biomass can be increased for 23 -35 times in 30 - 35 days, and the cultivation is performed under the dark conditions. The invention has the characteristics of low energy consumption and low cost, which is suitable for industrialization production.

The invention discloses a traditional Chinese medicine pharmaceutical composition for treating gynecological diseases, which is characterized by comprising 1-100 of kushenin and 1-50 of scutelloside according to the parts by weight, wherein 50 of the kushenin and 25 of the scutelloside are adopted according to the parts by weight. Pharmacological research shows that the pharmaceutical composition has certain actions for resisting bacteria, resisting inflammatory, relieving itching and resisting colpitis and provides an effectively pharmacological foundation for treating colpitis and cervicitis.

The invention discloses a quality control method of fructus xanthil dripping pills for treating rhinitis. In the method, a high performance liquid chromatography is used to measure the the content ofscutelloside, and octadecyl silane bonded silica gel is used as a filling agent; a methanol-water-phosphoric acid solution in volume ratio of 47:53:0.2 is used as a mobile phase at the rate of 1ml / min; the wave length for testing is 280 nm; the column temperature is 40 DEG C; a reference substance solution and a test sample solution are respectively and precisely absorbed and injected into a liquid chromatograph for the measurement; and the calculation is carried out according to the measurement result to obtain the content of the scutelloside in the fructus xanthil dripping pills for treatingrhinitis. The quality control method provides a method for measuring the content of the scutelloside in the fructus xanthil dripping pills for treating rhinitis, so that the quality control on the fructus xanthil dripping pills for treating rhinitis is more accurate and efficient, thereby providing convenience for ensuring the clinical efficacy. The method for measuring the content has the advantages of simple operation and accurate result as well as high precision, repetitiveness, stability and the like.

The invention discloses a method for controlling the quality of antipyrotic and antibacterial medicines, which comprises the following steps: firstly, identification: a, identification of rhubarb; and b, identification of phellodendron barks and Coptis chinensis; and secondly, content measurement of scutelloside: a, preparation of a sample solution; b, preparation of a reference solution; c, chromatographic conditions, namely octadecylsilane chemically bonded silica is taken as filler, and methanol and 0.2 percent phosphoric acid with a ratio of 40:60 are taken as mobile phases; the wavelength is controlled to be 280 nanometers; and the theoretical plate number is not less than 3,000 as calculated by the peak value of the scutelloside; and d, content measurement, namely 10 mu 1 of the reference solution and 10 mu 1 of the sample solution are precisely absorbed respectively and injected into a liquid phase chromatograph for measurement, and the content of the scutelloside in a sample is calculated. The method can quantitatively control the product quality of Yankening preparation, and is simple and convenient to operate.

The invention provides a method for determining the content of scutelloside in a throat-clearing granule by using high-performance liquid chromatography. The objective of the invention is to provide the method with the advantage of high analysis efficiency, and the method can be used as a quality control method for the throat-clearing granule. The method comprises the following steps: preparing a test solution; preparing a reference substance; and carrying out specific tests, precisely sucking 2 [mu]L of a reference substance solution, 2 [mu]L of the test solution and 2 [mu]L of a negative control solution, separately injecting the solutions into a liquid chromatograph, and carrying out detection, wherein chromatographic conditions are that a used chromatographic column is an Inertsil ODS-SP liquid chromatographic column, 5 [mu]m, 4.6*250 mm; a mobile phase is acetonitrile-0.5% acetic acid in a volume ratio of 44: 56; flow velocity is 0.8 mL / min; wavelength is 287 nm; and column temperature is 30 DEG C. The method belongs to the technical field of chemical detection.

A quality control method for the Chinese medicine 'Antihypertenssive Duzhong medicine' to treat hypertension includes such steps as examining its characteristics, identifying scutellaria root, uncaria stem with hooks and motherwort, and measuring the content of scutelloside.

A special air-permeable biological bacteriostasis pad for cotton seedling cultivation is prepared from 200-300 parts of rice straws, 20-30 parts of peanut shells, 15-25 parts of wheat straws, 20-30 parts of rice hulls, 2-4 parts of bone meal, 20-30 parts of leaf mold, 30-40 parts of plant ash, 2-4 parts of slaked lime, 60-70 parts of a nutrient solution, 3-5 parts of polysaccharide algin, 2-4 parts of an insectifuge extracted from various chrysanthemum flowers, named as Kujusu, 2-4 parts of Heliobacterium, 3-5 parts of sweet wormwood herb, 2-4 parts of Radix Euphorbiae Ebractealatae, 3-5 parts of Artemisia capillaries, 2-4 parts of Common Threewingnut Root, 2-4 parts of Radix Stemonae, 3-5 parts of rheum officinale, 2-4 parts of berberine, 1-3 parts of scutelloside and 2-4 parts of Falsehellebore Root and Rhizome. A making method of the special air-permeable biological bacteriostasis pad is simple; the pad contains nutrients needed by traditional seedbed matrixes, and seedbeds are made through adopting loose straws as a matrix, so the air permeability of the seedbeds is guaranteed, and superior environment needed by growth of cotton is provided, thereby cotton seedlings are nutritional and have good environment; and bacteriostasis Chinese patent medicinal materials are added to realize the efficacy of bacteriostasis and insect disinfestations, so healthiness and vigorousness are guaranteed in the cotton cultivation process.

The invention discloses a method for extracting scutelloside and scutellarin from baikal skullcap root. The method comprises the following steps of: (1) performing ultrasonic extraction on a solvent; (2) adsorbing Fe3O4 magnetic nanoparticles; and (3) performing desorption. The method is simple and rapid; separation of an absorption carrier and a feed liquid can be realized by additionally applying a magnetic field; scutelloside and scutellarin can be eluted selectively through different eluents, so that loss of raw materials and energy consumption is avoided, and cost is reduced effectively; and Fe3O4 magnetic nanoparticles can be used circularly, so that cost can be saved effectively.