882results about "Male contraceptives" patented technology

An external incontinence clamp for stopping involuntary voiding of urine is provided. The clamp includes a first rigid member having opposed ends, each end defining a passage extending therethrough, a second rigid member having opposed ends, each end defining a passage extending therethrough, and two pins of generally u-shape. The pins are adapted to be received by the passages defined by the ends of the first rigid member and of the second rigid member so as to secure the first rigid member in a spaced and generally parallel relationship to the second rigid member. The penis is positioned between the first and second members so that the underside of the penis is in contact with the second member and the top surface of the penis is in contact with the first member, thereby stopping involuntary voiding of urine. A clamp kit includes a plurality of pins of different width to vary the force applied to the penis.

The invention is drawn to silane copolymers prepared from the reaction of one or more polyisocyanates with one or more lubricious polymers having at least two functional groups, which may be the same or different, that are reactive with an isocyanate functional group and with one or more organo-functional silanes having at least two functional groups, which may be the same or different, that are reactive with an isocyanate functional group and at least one functional group reactive with a silicone rubber substrate. The silane copolymer coatings of the invention are elastic, lubricious, and resist wet abrasion. They are useful as coatings for polysiloxane (rubber) and other difficult to coat substrates, especially for medical devices, such catheters.

An occlusion clip for permanently occluding a bodily vessel, such as the vas deferens. The occlusion clip has a first leg, a second leg, joined on their proximal ends by a spring coil. The spring coil provides a biased torsional force to the first leg and the second leg, to force them into a closed position. The first leg and the second leg have on their distal ends a vessel occlusion portion that occludes the targeted vessel when the clip is in a closed position.

The invention described is directed to an intracorporeal occluding device having elements with non-traumatic ends and devices, systems and methods for occluding the lumens of anatomical passageways and / or for delivering drugs or other substances to the bodies of human or animal subjects.

A device and method of using the device for contraception or sterilization and particularly for reversible contraception by occluding a reproductive lumen to prevent the passage of reproductive cells through the lumen for a desired period of time until the patient wishes to become fertile again and then be reopened. The occluding member preferably comprises a tubular framework formed from a shape memory material configured to be implanted in a reproductive lumen. The occluding member is implanted within a body lumen, secured to the wall of the reproductive lumen and then collapsed to collapse the wall and occlude the lumen. Alternatively, the occluding member may be collapsed upon a solid plug. The closure of the reproductive lumen may be reversed by introducing a balloon catheter and by a series of inflations of the balloon reexpanding the collapsed occluding member or by removing the plug. The occluding member and the plug may be configured to facilitate endothelialization, to provoke an inflammatory responses or to deliver a drug.

The present invention relates to formulations of nucleotide reverse transcriptase inhibitors (N(t)RTIs), preferably [2-(6-Amino-purin-9-yl)-1-methyl-ethoxymethyl]-phosphonic acid (tenofovir, PMPA), or a physiologically functional derivative thereof, suitable for topical application and their use in the prevention of HIV infections.

A material composition including a flexible, polymeric matrix and a reverse-thermochromic colorant is described. When subjected to a heat source, the polymeric material can change color from a pale or neutral color to a darker or more vibrant color of a Delta E (ΔE) change of >3. The reverse-thermochromic colorant exhibits a color change when exposed to a heat source within a period of about 30 seconds, and is observable by an unaided human eye under either natural daylight or ambient artificial normal lighting conditions. One or more different reverse-thermochromic colorants in combination may be incorporated. The polymeric matrix surrounds or encapsulates a solvatochromic dye molecule with a phenolate betaine structure. The polymeric matrix includes a dipole orientating agent that induces said solvatochromic dye to express locally when subjected to a temperature change. Various uses for the composition and articles that incorporate the composition are also described, in addition to a method of indicating the temperature of an object or environmental condition.

The present invention discloses one kind of composite material of modified micro plant fiber powder and natural rubber and its preparation process and application. The composite material includes natural rubber or latex 100 weight portions, modified micro plant fiber powder 1-60 weight portions, sulfur 0.5-3.3 weight portions, promoter 1.2-4.3 weight portions, antiager 1-3 weight portions and other assistant. The preparation process includes mixing, forming, vulcanizing and other steps. The composite material has high tensile strength, high tearing strength, high ageing resistance, high virus permeation resistance, etc. and may be used widely in making urinary catheter, blood transfusion tube, condom, medical gloves and other products.

Male, hermaphroditic, and female condoms that exert lateral pressure on the penis and the vagina of a man and a woman respectively are disclosed. The lateral pressure is exerted by the geometry of the condoms themselves upon application or is exerted by means for exerting such lateral pressure located or applied on the condoms which means are normally activated by the user after the condoms are applied. User activated lateral pressure is controllable by the user within safe limits or, once activated by the user, is designed to be within safe limits. The lateral pressure retains the condoms securely in position to act as contraceptive and prophylactic barriers between the male and female genital areas, while increasing stimulation during intercourse.

A transuterine cannula through which an endoscope can be advanced into the peritoneal space to provide visualization of tissue cutting in the peritoneal space pursuant to a vaginal hysterectomy.

An absorbable and expandable closure member used to occlude or exclude a body lumen or cavity, such as a blood vessel, fallopian tube, duct, aneurysmal sac, etc., comprising a closure member comprising one of more sheets of a biomaterial that are rolled, stacked, or folded to form a multilayer construct of a generally cylindrical configuration for deployment through a delivery system, either as a singularly or part of a multiplicity of closure members. The biomaterial is derived from a source material, such as small intestinal submucosa or another remodelable material (e.g., an extracellular matrix) having properties for stimulating ingrowth of adjacent tissue into the biomaterial deployed within the bodily lumen. The closure member is deployed to the bodily lumen from a delivery sheath, cartridge, and / or over a inner guiding member, such as a wire guide or catheter.

The present invention generally relates to the transdermal delivery of substances and, in some embodiments, to the transdermal delivery of beneficial substances by a hostile biophysical environment. In one aspect, various methods for the transdermal delivery of beneficial substances are disclosed. By creating a hostile biophysical environment, beneficial substances may be delivered, according to certain embodiments, through the stratum corneum of the skin into the body. Beneficial substances include, but are not limited to, pharmaceutical agents, drugs, vitamins, co-factors, peptides, dietary supplements, and others. The beneficial effects disclosed include, for instance, relief of pain and inflammation, prevention and healing of ulcers of the skin, relief of headache, improved sexual function and enjoyment, growth of hair on the scalp, improving muscle size and / or function, removing body fat and / or cellulite, treating cancer, treating viral infections and others. A hostile biophysical environment may also be used in conjunction with systems and methods for increasing local blood flow, according to one set of embodiments. For example, by using a nitric oxide donor such as L-arginine, local blood flow may be increased, e.g., by transdermally delivering the nitric oxide precursor. The nitric oxide donor may be the sole cause of increased blood flow, or it may be supplemented with an adjunct such as theophylline.

A formulation for male contraception comprising a progestin possessing both estrogenic and androgenic properties is remarkably effective for spermatogenesis suppression in males. The progestin Norethisterone (NET), particularly its derivatives Norethisterone acetate and Norethisterone enanthate in sufficient doses induce oligozoospermia or azoospermia in males. Formulations further comprising an androgen, such as a testosterone derivative such as a testosterone ester, particularly testosterone undecanoate, are especially effective male contraceptive formulations.

An expandable polymeric medical article is formed by a novel dip-molding process, involving multiple dipping and rotational drying of liquid polymeric material layer at different pivotal positions. Preferably, the rotational drying is conducted so as to form an expandable polymeric medical article having a reverse thickness gradient in relation to the thickness gradient of conventional dip-molded polymeric medical articles. Specifically, the expandable polymeric medical article of the present invention has an expandable body member and a neck member, wherein such neck member has a wall thickness that is greater than that of the expandable body member, before any significant expansion of such body member.

A condom has an erectogenic compound immobilised on the interior surface and substantially at the head end thereof. The compound may be applied as a component of a composition comprising the erectogenic compound dispersed or dissolved in a gel carrier comprising a liquid medium including a thickening agent. The condom may include a lubricant which may be immiscible with the erectogenic compound or composition. Use of the condom sustains e penile erection following spontaneous initiation thereof, to prevent slippage of the condom off the penis while intercourse takes place.

An elastomeric article (e.g., glove, condom, and so forth) coated with a hydrogel is provided. The hydrogel coating facilitates dry and / or damp donning. In addition, due its low coefficient of friction, the hydrogel allows stripping of a dip-formed article without the use of an antiblocking powder. Thus, the present inventors have discovered that certain treatment steps, such as chlorination and / or lubrication, conventionally conducted “off-line” (i.e., after stripping) are no longer required. Moreover, even when such treatments are used, they may conducted “in-line” (i.e., before stripping). The ability to eliminate certain off-line treatment steps provides a significant improvement in the efficiency of the forming process.

The invention described is directed to an intracorporeal occluding device having elements with non-traumatic ends and devices, systems and methods for occluding the lumens of anatomical passageways and / or for delivering drugs or other substances to the bodies of human or animal subjects.

A medical device or system may include an anchor capable of grasping tissue, rotating the tissue, and / or occluding a space in communication with the tissue. A method for occluding a space within a patient may include grasping tissue, rotating the tissue, and / or occluding a space in communication with the tissue.

To use a loose-fitting condom, a penis or prosthesis is covered loosely with a condom having a loose-fitting portion. The loose-fitting portion is twisted so that the loose-fitting portion closely covers the penis or prosthesis. The loose-fitting portion is then secured in the twisted state. An external penile prosthesis is provided, which includes a generally tubular body portion and a head portion. The head portion can be rotatable about the central axis of the body portion or include a plurality of flaps swingably attached to the body portion for adjusting an opening between the flaps. Further provided is a combination of the prosthesis and a loose-fitting condom. The condom has a flexible sheath which has a loose-fitting portion sized for loosely covering a penis or the prosthesis. The combination may further include a holder for holding the loose-fitting condom in a twisted position.