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7680 results about "Low toxicity" patented technology
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Low Toxicity Substances. These substances are considered to be low toxicity when ingested. They may cause irritation to the mouth or mild gastrointestinal upset but other features are unlikely. Medical treatment is usually not required but you should consult your GP or local Emergency Department if: a large amount has been taken persisting...
Coated implantable medical device
InactiveUS6918927B2Good worker safetyLow costOrganic active ingredientsSurgerySodium bicarbonateMedicine
A medical device (10) includes a structure (12) adapted for introduction into a patient, the structure (12) being formed of a preferably non-porous base material (14) having a roughened or textured surface (16). The structure (12) is conveniently configured as a vascular stent with a base material (14) of stainless steel, nitinol or another suitable material. The medical device (10) also includes a layer (18) of a bioactive material posited directly upon the roughened or textured surface (16) of the base material (14) of the structure (12). The surface (16) of the base material (14) is roughened or textured by etching or by abrasion with sodium bicarbonate or another suitable grit. A preferred roughened or textured surface (16) is thought to have a mean surface roughness of about 10 μin. (about 250 nm) and a surface roughness range between about 1 μin. and about 100 μin. (about 25 nm and about 2.5 μm). The particularly preferred use of sodium bicarbonate as the abrasive to provide roughness or texture to the surface (16) of the base material (14) of the structure (12) is additionally advantageous in the low toxicity of the sodium bicarbonate to production workers, the ease of product and waste cleanup, and the biocompatibility of any residual sodium bicarbonate.
Owner:COOK MEDICAL TECH LLC
Nanoemulsion compositions having anti-inflammatory activity
InactiveUS20070036831A1Minimizing microbial resistanceMinimize ToxicityAntibacterial agentsBiocidePathogenic microorganismDisease
Nanoemulsion compositions with low toxicity that demonstrate broad spectrum inactivation of microorganisms or prevention of diseases are described. The nanoemulsions contain an aqueous phase, an oil phase comprising an oil and an organic solvent, at least one anti-inflammatory agent, and one or more surfactants. Methods of making nanoemulsions and inactivating pathogenic microorganisms are also provided.
Owner:NANOBIO CORP
Compositions for inactivating pathogenic microorganisms, methods of making the compositions, and methods of use thereof
InactiveUS20060251684A1Reduce infectivityReduce morbiditySsRNA viruses negative-senseAntibacterial agentsPathogenic microorganismOrganic solvent
Owner:NANOBIO CORP
Insecticide
InactiveCN102613183AHigh insecticidal activityGood effectBiocideAnimal repellantsStructural formulaToxicology
The invention discloses an insecticide for agricultural pests. The insecticide contains 3-chloro-N<1>-(2-methyl-4-heptafluoroisopropyl phenyl)-N<2>-(1-methyl-1-cyanoethyl)phthalic diamide shown as a structural formula (I). The insecticide has ultrahigh insecticidal activity, high safety, reasonable toxicity, ecological toxicity and environmental compatibility, and belongs to a low-toxicity and environment-friendly pesticide.
Owner:SINOCHEM LANTIAN +1
Substituted diaryl compound and preparation method and antiviral application thereof
ActiveCN102206172ALess likely to develop drug resistanceImprove securityCarbamic acid derivatives preparationSulfonic acid esters preparationMechanism of actionStructure–activity relationship
The invention provides substituted diaryl compounds as shown in general formula (I) or their pharmaceutically acceptable salts, and also provides a preparation method; a class of novel broad-spectrum antiviral compounds and pharmaceutical salts targeting cytokines are screened and obtained through studies on structure-activity relationship and action mechanism of active compounds; the compounds not only have significant broad-spectrum antiviral activity, but also have the advantages of low toxicity and good pharmaceutical properties.
Owner:MEDICINE & BIOENG INST OF CHINESE ACAD OF MEDICAL SCI
Compositions for inactivating pathogenic microorganisms, methods of making the compositons, and methods of use thereof
InactiveUS20050208083A1Reduce infectivityReduce morbidityAntibacterial agentsSsRNA viruses negative-sensePathogenic microorganismOrganic solvent
Nanoemulsion compositions with low toxicity that demonstrate broad spectrum inactivation of microorganisms or prevention of diseases are described. The nanoemulsions contain an aqueous phase, an oil phase comprising an oil and an organic solvent, and one or more surfactants. Methods of making nanoemulsions and inactivating pathogenic microorganisms are also provided.
Owner:NANOBIO CORP
Porous particulate collagen sponges
InactiveUS20060135921A1Low toxicitySatisfactory porosityCosmetic preparationsToilet preparationsParticulatesCross-link
The present invention relates to the development of new porous particulate collagen sponges, combining the desirable features of low toxicity, resorbability, and satisfactory porosity, particularly when wetted in an aqueous medium. Accordingly, the present invention is directed to new porous, particulate, dehydrothermally cross-linked, wetted sponges, as well as a process for making them.
Owner:WIERCINSKI ROBERT A +2
Medical devices having antimicrobial coatings thereon
InactiveUS20050008676A1Improve antibacterial propertiesLow cytotoxicityAntibacterial agentsBiocideMetal coatingExtended wear contact lenses
The present invention provides a medical device, preferably a contact lens, which a core material and an antimicrobial metal-containing LbL coating that is not covalently attached to the medical device and can impart to the medical device an increased hydrophilicity. The antimicrobial metal-containing coating on a contact lens of the invention has a high antimicrobial efficacy against microorganisms including Gram-positive and Gram-negative bacterial and a low toxicity, while maintaining the desired bulk properties such as oxygen permeability and ion permeability of lens material. Such lenses are useful as extended-wear contact lenses. In addition, the invention provides a method for making a medical device, preferably a contact lens, having an antimicrobial metal-containing LbL coating thereon.
Owner:NOVARTIS AG
Method of treating an oil or gas well with biodegradable low toxicity fluid system
InactiveUS7231976B2Well remediationIncrease stimulationCleaning apparatusFluid removalMETHYL SOYATEFluid system
Owner:BAKER HUGHES HLDG LLC
Method of treating an oil or gas well with biodegradable low toxicity fluid system
InactiveUS7392844B2Well remediationIncrease stimulationConstructionsCleaning apparatusMETHYL SOYATEFluid system
Owner:BAKER HUGHES INC
Hydroxypropyl-Sulfobutyl-Beta-Cyclodextrin, the Preparation Method, the Analytical Method, and the Pharmacutical Application Thereof
ActiveUS20090012042A1Little hemolysisLow toxicityBiocideOrganic active ingredientsHaemolysisCyclodextrin
Hydroxypropyl-sulfobutyl-&bgr;-cyclodextrin, the preparation method, analytical method, and the pharmaceutical application thereof. The hydroxypropyl-sulfobutyl-&bgr;-cyclodextrin is a derivate of cyclodextrin which is substituted by hydroxypropyl group and sulfobutyl group: n-(2,3,6-O-2-hydroxypropyl)-m-(2,3,6-O-sulfobutyl)-&bgr;-cyclodextrin. The number of substituent groups per mole cyclodextrin is n hydroxypropyl groups and m sulfobutyl groups. “n” represents the average substituent degree of hydroxypropyl groups; “m” represents the average substituent degree of sulfobutyl groups; “n+m=z” is the gross average substituent degree, in which n is a random integer chosen from 1, 2, 3, 4, 5, 6, 7, 8, 9; m is a random integer chosen from 1, 2, 3, 4, 5, 6, 7, 8, 9; and the gross average substituent degree z is a random integer chosen from 2, 3, 4, 5, 6, 7, 8, 9, 10. The present invention shows low haemolysis and low toxicity.
Owner:SUN XIAODONG
Irradiation cross-linking oil resistance type soft low smoke zero halogen flame-retardant cable material
ActiveCN102070821AGood oil resistanceGood flexibilityPlastic/resin/waxes insulatorsCross-linkSilanes
The invention provides an irradiation cross-linking oil resistance type soft low smoke zero halogen flame-retardant cable material which comprises the following components in parts by weight: 60-90 parts of ethylene-vinylacetate copolymer, ethylene-propylene-diene rubber and ethylene-octylene copolymer, 0-20 parts of nitrile rubber, 10-30 parts of interface compatilizer, 80-130 parts of flame retardant, 2-15 parts of flame-retardant synergist, 0.5-1.0 part of antioxidant, 1-2 parts of cross-linking sensitizing agent and 0.5-1.0 part of lubricant. The preparation method of the cable material in the invention mainly comprises the steps of silane surface modification treatment of the flame retardant, mixing and extruding of a double screw mixer-extruder unit or an internal mixer unit, brace water cooling or water ring particle cutting and the like. The cable material provided by the invention has the advantages of superior flame resistance (single cable can vertically burn), good mechanical properties, especially high softness, oil resistance, high-temperature resistance (the cable material can be used in a range of minus 40 DEG C-125 DEG C), low smoke, low toxicity and excellent processability.
Owner:JIANGSU DEWEI ADVANCED MATERIALS
2-(3-cyano-4-isobuoxy phenyl)4-methyl-5-thiazole aminic acid crystal and preparation method thereof
The present invention discloses two crystal models and the preparation method of the anti-hyperuricemia drug 2-(3-ayano-4-isobuoxy phenyl)-4-methyl-5- thiazole acid. The preparation method of the crystal models commonly uses the low-toxicity ethanol, ethyl acetate or acetone as the solvent; the safety is relatively high. In addition, the hygroscopicity of the two crystal models is low in the high-humidity environment and the two crystal models are suitable for the steady pharmaceutical preparation.
Owner:SHANGHAI INST OF PHARMA IND CO LTD +1
Tumor activated prodrug compounds and methods of making and using the same
InactiveUS20040014652A1Improved therapeutic propertyLow toxicityIn-vivo radioactive preparationsPeptide/protein ingredientsHalf-lifeIn vivo
The invention is directed to novel prodrug compounds, compositions comprising the prodrug compounds, methods of making the prodrug compounds and methods of using the prodrug compounds. The prodrug compounds comprise a biologically active entity linked to a masking moiety via a linking moiety. The prodrug compounds are selectively activated at or near target cells and display lower toxicity and possibly a longer in vivo or serum half-life than the corresponding naked biologically active entity.
Owner:UNIVERSITE CATHOLIQUE DE LOUVAIN
Method of treating an oil or gas well with biodegradable low toxicity fluid system
InactiveUS20060096757A1Increase stimulationWell remediationCleaning apparatusFluid removalMETHYL SOYATEAlcohol
A method of treating a well consists of introducing into the wellbore a biodegradable fluid system containing a blend of lactic acid ester, such as ethyl lactate, and a fatty acid ester, such as methyl soyate. The fluid system may be further in the form of a microemulsion that is formed by combining a blend with one or more emulsifiers, an alcohol, and water. The fluid system may be used in displacement, well remediation and stimulation as well as additional, alternative applications such as the cleaning of surface and / or downhole equipment.
Owner:BAKER HUGHES INC
Biomedical TiZrNbTa high-entropy alloy and preparation method thereof
The invention discloses a biomedical TiZrNbTa high-entropy alloy and a preparation method thereof. The high-entropy alloy has a chemical formula of (TiaZrb)x(NbcTad)yMz; the atomic percents of all components are as follows: a not more than 35 at% and not less than 0, b not more than 35 at% and not less than 0, c not more than 35 at% and not less than 0, d not more than 35 at% and not less than 0, a+b=x, c+d=y, x not more than 70 at% and not less than 5, y not more than 70 at% and not less than 5, M is any one or more in V, Mo, Sn, W, Mn, Al, Fe, Co, Ni, Cu, Cr and Zn, z not more than 35 at% and not less than 0, and x+y+z=100. The alloy is higher in strength, excellent in plasticity and low in Young modulus; the components of the alloy is free of poison on human bodies, or are low-toxicity elements to satisfy the biomedical demands; and the high-entropy alloy is broad in application prospect in the aspect of biomedical materials.
Owner:UNIV OF SCI & TECH BEIJING
General A-type foam extinguishing agent easy to degrade
ActiveCN102886114AEfficient fire fightingImprove the protective effectFire extinguisherFoaming agentPreservative
The invention discloses a general A-type foam extinguishing agent easy to degrade. The general A-type foam extinguishing agent easy to degrade comprises the following components in parts by weight: 8%-25% of main foaming agents, 5%-20% of auxiliary foaming agents, 20%-40% of cosolvents, 0.1%-5% of foam stabilizers and the balance of water, and also comprises a proper amount of wetting penetrating agents, corrosion inhibitors and preservatives. The foam extinguishing agent has the characteristics of excellent fire extinguishing, heat-insulation protection performance and low toxicity, and can be used for rapidly fighting commonly-seen solid fire and liquid fire.
Owner:应急管理部天津消防研究所
Composite bactericidal composite and applications thereof
ActiveCN101796955AReduce pollutionRelieve stressBiocideFungicidesAdditive ingredientPesticide formulation
The invention belongs to the technical field of pesticide formulation and in particular relates to a composite bactericidal composite and applications thereof in aspect of preventing and curing the fungicidal and bacteria diseases of grains, fruits and vegetables. The composite bactericidal composite comprises effective ingredient A and B, wherein the effective ingredient A is prochloraz or othermetal salt composite, and the effective ingredient B comprises at least one of penconazole, imazalil sulfate, ethirimol, bupirimate, SYP-Z048, thifluzamide, mandipropamid, ethaboxam, polyoxin, polyoxin B, benziothiazolinone, famoxadone, dithianon and zinc thiazole. The composite has high efficiency, low toxicity, low residue, good environment compatibility and low cost.
Owner:QINGDAO STAR CROPSCI
Hydrogel
InactiveUS20060052478A1The way is simple and fastOptical articlesCoatingsCross-linkHydrophilic polymers
A method of preparation of a cross-linked hydrogel by graft copolymerisation, said method comprises the steps of preparing an aqueous solution comprising one or more hydrophilic polymers, a cross-linking agent and a photoinitiator comprising a water-soluble peroxydisulphate, subjecting said solution to irradiation and obtaining the cross-linked hydrogel, wherein the hydrophilic polymers are saturated and the cross-linking agent acts as a co-catalyst of cross-linking. The hydrogel is fast to produce and has low toxicity. The hydrogel may be suitable for use in medical devices such as dressings and the like.
Owner:COLOPLAST AS
Beneficiation method for recovering zinc, lead and silver from zinc leaching residue
The invention discloses a beneficiation method for recovering zinc, lead and silver from a zinc leaching residue. The method basically comprises the following steps of: recovering water-soluble zinc by a washing, zinc leaching and precipitating method to obtain a zinc concentrate; and recovering lead and silver to obtain a lead-silver concentrate by a disperse, size mixing, surface modifying and floating method. When the zinc content in the precipitate obtained by the washing, zinc leaching and precipitating method is lower, selective floating and enriching are carried out on the precipitate to obtain the zinc concentrate; and selective size mixing and floating are carried out on the leaching residue to recover indissoluble zinc in the leaching residue and then the indissoluble zinc is sent to a lead and silver recovery system. The method has the advantages that the process is simple, and required equipment investment is less; the production cost is low to ensure that an economical treatment method is found for the zinc leaching residue with a low zinc content; roasting with coal is not needed, thus the smoke pollution problem is avoided; return water can be recycled; and floatingtailings are subjected to low-toxicity treatment, and dry stockpiling can be used for replacing full size tailings library stockpiling, therefore, potential safety hazards of the full size tailings library are eliminated.
Owner:HUNAN HUAQI RESOURCES ENVIRONMENT SCI & TECH DEV CO LTD
Low toxicity primer compositions for reduced energy ammunition
InactiveUS20100300319A1Increased heat generationHigh sensitivityAmmunition projectilesShotgun ammunitionToxic materialOxidizing agent
A primer composition with reduced toxicity suited for reduced-energy ammunition comprises bismuth (III) oxide as the principal oxidizer and contains a portion of propellant composition mixed therein. This composition may also be used in a cartridge which is otherwise substantially free of any other propellant compound and preferably produces a residue which is substantially free of toxic substances.
Owner:GENERAL DYNAMICS ORDNANCE & TACTICAL SYST CANADA VALLEYFIELD INC
Preparation method of zebrafish with hepcidin gene knocked out by use of CRISPR / Cas9 technology
The present invention mainly relates to formation of zebrafish with hepcidin gene knocked out, by the use of CRISPR / Cas9 technology, a unique PAM region is designed, so that the hepcidin gene in the zebrafish is knocked out, and other genes are not accidentally injured. The first case of hepcidin knockout transgenic animal model zebrafish has great significance, the hepcidin is a major factor in the regulation of iron, once the hepcidin is knocked out, an animal model can be successfully molded into an iron overload animal model, the human factor intervention can be excluded, the hepcidin has great significance to iron expression researches, meanwhile compared with the traditional gene knockout technology, the CRISPR / Cas9 technology has low toxicity, high accuracy, high efficiency, short success cycle and other characteristics, and the hepcidin gene can be faster knocked out.
Owner:徐又佳
Heterocyclic compound
InactiveUS20080113961A1Good immunosuppressive activityLow toxicityBiocideSenses disorderMedicinal chemistryProdrug
A compound having immunosuppressive activity with low toxicity or a pharmacological salt thereof. The compound has a general formula (I) shown below or a pharmacologically acceptable salt thereof, or a pharmacologically acceptable prodrug thereof
Owner:DAIICHI SANKYO CO LTD
Halogen-free flame retardant thermoplastic polyolefin cable material
The invention discloses a halogen-free flame retardant thermoplastic polyolefin cable material. The cable material consists of the following components in parts by weight: 0-40 parts of polyethylene resin, 20-80 parts of ethylene copolymer, 20-40 parts of compound flame retardant, 5-20 parts of compatilizer, 4-50 parts of flame retardant synergist, 1-4 parts of coupling agent, 0.5-4 parts of antioxidant and 1-10 parts of processing aid. According to the halogen-free flame retardant thermoplastic polyolefin cable material disclosed by the invention, the flame retardant is formed by compounding a borate flame retardant and a phosphorus nitrogen flame retardant; by adding a small amount of compound flame retardant, the cable material obtains a good flame retardant effect and an excellent smoke suppression effect; and the cable material has low smoke density and low toxicity index.
Owner:GUANGDONG JUSHI CHEM CO LTD
Preparation method of micro-emulsion absorption liquid used for processing organic exhaust gas
The invention relates to a preparation method of an organic exhaust gas micro-emulsion absorption liquid, and a method for applying the micro-emulsion absorption liquid for cleaning industrial organic exhaust gas comprising benzene, toluene, xylene, and the like. The invention belongs to the technical field of atmosphere pollution control. The absorption liquid is prepared from the components of, by mass, 80-90% of water, 0.5-3% of a surfactant, 7-19.5% of a coupling agent, and 0.02-0.06% of an auxiliary agent. The surfactant is sufficiently mixed with water, such that a surfactant solution is obtained; the auxiliary agent is dissolved in water, such that an auxiliary agent solution is obtained; the two solutions are combined and uniformly mixed; and the coupling agent is added, and the obtained solution is stirred, such that the organic exhaust gas micro-emulsion absorption liquid is obtained. The organic exhaust gas micro-emulsion absorption liquid is suitable to be used for controlling exhaust gas containing benzene-series volatiles, and has the advantages of convenient raw material source, low cost, mild and stable property, low toxicity, environment-friendliness, no absorption tower corrosion or blocking phenomena, no severe influence to human health, high removal rate to organic exhaust gas, no need of pretreatment upon exhaust gas, and low investment and running cost. Saturated absorption liquid and absorbed organics can be recycled, such that waste can be turned useful.
Owner:GUANGZHOU INST OF GEOCHEMISTRY - CHINESE ACAD OF SCI
Method of manufacturing nickel zinc batteries
ActiveUS20050064292A1Improve efficiencyFinal product manufactureElectrode carriers/collectorsZinc compoundsSlurry
Methods of manufacturing a rechargeable power cell are described. Methods include providing a slurry or paste of negative electrode materials having low toxicity and including dispersants to prevent the agglomeration of particles that may adversely affect the performance of power cells. The methods utilize semi-permeable sheets to separate the electrodes and minimize formation of dendrites; and further provide electrode specific electrolyte to achieve efficient electrochemistry and to further discourage dendritic growth in the cell. The negative electrode materials may be comprised of zinc and zinc compounds. Zinc and zinc compounds are notably less toxic than the cadmium used in NiCad batteries. The described methods may utilize some production techniques employed in existing NiCad production lines. Thus, the methods described will find particular use in an already well-defined and mature manufacturing base.
Owner:ZINCFIVE POWER INC
Pesticide missible oil preparation containing biological diesel oil solvent
InactiveCN101194606AImprove low temperature fluidityWide application areaBiocideAnimal repellantsBiodieselAdditive ingredient
The invention relates to an agricultural chemical missible oil preparation with biological diesel oil dissolvent, the ingredient comprises agricultural chemical original raw pesticide, dissolvent, and emulsifying agent, wherein the dissolvent is biological diesel oil or is mixed dissolvent which is mixed by biological diesel oil and conventional agricultural chemical in any proportion. The invention uses biological diesel oil as dissolvent to replace or partially replace conventional dissolvent in the prior art, which has the advantages of high efficiency, safety, environmental protection, and low toxicity, and can reduce the cost of agricultural chemical.
Owner:湖南万家丰科技有限公司
Soft low-smoke halogen-free flame-retardant polyolefin cable material and preparation method thereof
InactiveCN101817952ABright surfaceImprove flame retardant performancePlastic/resin/waxes insulatorsInsulated cablesLinear low-density polyethylenePolyolefin
The invention discloses a soft low-smoke halogen-free flame-retardant polyolefin cable material and a preparation method thereof. The cable material comprises the following components (based on by mass part ratio): 80-90 parts of copolymer of ethylene-vinylacetate, 10-20 parts of linear low-density polyethylene, 65-130 parts of an inorganic fire retardant through surface treatment, 10-30 parts of high-effective flame retardant synergist, 10-20 parts of high molecular compatilizer, 0.9-1.5 parts of antioxidant and 1-2 parts of processing aid. The preparation method comprises the steps of resin blending extrusion; surface treatment of the inorganic fire retardant; batching, mixing, extrusion, granulation and the like. Compared with the prior art, the invention has the characteristics of predominant flame retardation (an oxygen index up to 36), excellent toughness, excellent bending resistance, low density (density is only 1.28g / cm<3>), low smoke, low corrosion, low toxicity, environmental protection, good processability, bright surface of extrudates and the like.
Owner:XI AN JIAOTONG UNIV +1
Liquid Compositions Containing Urease Inhibitors and Glycol Alkyl Ethers and Methods of Making a Use Thereof
ActiveUS20140047883A1Agriculture gas emission reductionUrea compound fertilisersSolubilityNitrification inhibitors
The present invention provides improved solvent systems for the preparation of liquid formulations of urease or nitrification inhibitors, specifically NBPT, comprising alkylene glycol alkyl ethers. The solvent systems provided good solubility of the urease inhibitor as well as at least one of improved stability, lower flammability, lower toxicity, improved cold temperature storage, improved handling, improved adsorption onto and / or solubility with solid media such as UFP or urea. Methods of making and using the compositions are also provided.
Owner:KOCH AGRONOMIC SERVICES LLC
Drug delivery system and preparation method thereof
InactiveCN101485629AHigh feasibilityImprove stabilityLyophilised deliveryEmulsion deliveryOrganic solventSide effect
Owner:SHENYANG PHARMA UNIVERSITY
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