7674 results about "Low toxicity" patented technology

Nanoemulsion compositions with low toxicity that demonstrate broad spectrum inactivation of microorganisms or prevention of diseases are described. The nanoemulsions contain an aqueous phase, an oil phase comprising an oil and an organic solvent, at least one anti-inflammatory agent, and one or more surfactants. Methods of making nanoemulsions and inactivating pathogenic microorganisms are also provided.

The invention provides substituted diaryl compounds as shown in general formula (I) or their pharmaceutically acceptable salts, and also provides a preparation method; a class of novel broad-spectrum antiviral compounds and pharmaceutical salts targeting cytokines are screened and obtained through studies on structure-activity relationship and action mechanism of active compounds; the compounds not only have significant broad-spectrum antiviral activity, but also have the advantages of low toxicity and good pharmaceutical properties.

Nanoemulsion compositions with low toxicity that demonstrate broad spectrum inactivation of microorganisms or prevention of diseases are described. The nanoemulsions contain an aqueous phase, an oil phase comprising an oil and an organic solvent, and one or more surfactants. Methods of making nanoemulsions and inactivating pathogenic microorganisms are also provided.

The present invention provides a medical device, preferably a contact lens, which a core material and an antimicrobial metal-containing LbL coating that is not covalently attached to the medical device and can impart to the medical device an increased hydrophilicity. The antimicrobial metal-containing coating on a contact lens of the invention has a high antimicrobial efficacy against microorganisms including Gram-positive and Gram-negative bacterial and a low toxicity, while maintaining the desired bulk properties such as oxygen permeability and ion permeability of lens material. Such lenses are useful as extended-wear contact lenses. In addition, the invention provides a method for making a medical device, preferably a contact lens, having an antimicrobial metal-containing LbL coating thereon.

The invention is directed to novel prodrug compounds, compositions comprising the prodrug compounds, methods of making the prodrug compounds and methods of using the prodrug compounds. The prodrug compounds comprise a biologically active entity linked to a masking moiety via a linking moiety. The prodrug compounds are selectively activated at or near target cells and display lower toxicity and possibly a longer in vivo or serum half-life than the corresponding naked biologically active entity.

A method of treating a well consists of introducing into the wellbore a biodegradable fluid system containing a blend of lactic acid ester, such as ethyl lactate, and a fatty acid ester, such as methyl soyate. The fluid system may be further in the form of a microemulsion that is formed by combining a blend with one or more emulsifiers, an alcohol, and water. The fluid system may be used in displacement, well remediation and stimulation as well as additional, alternative applications such as the cleaning of surface and/or downhole equipment.

The invention discloses a biomedical TiZrNbTa high-entropy alloy and a preparation method thereof. The high-entropy alloy has a chemical formula of (TiaZrb)x(NbcTad)yMz; the atomic percents of all components are as follows: a not more than 35 at% and not less than 0, b not more than 35 at% and not less than 0, c not more than 35 at% and not less than 0, d not more than 35 at% and not less than 0, a+b=x, c+d=y, x not more than 70 at% and not less than 5, y not more than 70 at% and not less than 5, M is any one or more in V, Mo, Sn, W, Mn, Al, Fe, Co, Ni, Cu, Cr and Zn, z not more than 35 at% and not less than 0, and x+y+z=100. The alloy is higher in strength, excellent in plasticity and low in Young modulus; the components of the alloy is free of poison on human bodies, or are low-toxicity elements to satisfy the biomedical demands; and the high-entropy alloy is broad in application prospect in the aspect of biomedical materials.

The invention discloses a general A-type foam extinguishing agent easy to degrade. The general A-type foam extinguishing agent easy to degrade comprises the following components in parts by weight: 8%-25% of main foaming agents, 5%-20% of auxiliary foaming agents, 20%-40% of cosolvents, 0.1%-5% of foam stabilizers and the balance of water, and also comprises a proper amount of wetting penetrating agents, corrosion inhibitors and preservatives. The foam extinguishing agent has the characteristics of excellent fire extinguishing, heat-insulation protection performance and low toxicity, and can be used for rapidly fighting commonly-seen solid fire and liquid fire.

The invention belongs to the technical field of pesticide formulation and in particular relates to a composite bactericidal composite and applications thereof in aspect of preventing and curing the fungicidal and bacteria diseases of grains, fruits and vegetables. The composite bactericidal composite comprises effective ingredient A and B, wherein the effective ingredient A is prochloraz or othermetal salt composite, and the effective ingredient B comprises at least one of penconazole, imazalil sulfate, ethirimol, bupirimate, SYP-Z048, thifluzamide, mandipropamid, ethaboxam, polyoxin, polyoxin B, benziothiazolinone, famoxadone, dithianon and zinc thiazole. The composite has high efficiency, low toxicity, low residue, good environment compatibility and low cost.

The invention discloses a beneficiation method for recovering zinc, lead and silver from a zinc leaching residue. The method basically comprises the following steps of: recovering water-soluble zinc by a washing, zinc leaching and precipitating method to obtain a zinc concentrate; and recovering lead and silver to obtain a lead-silver concentrate by a disperse, size mixing, surface modifying and floating method. When the zinc content in the precipitate obtained by the washing, zinc leaching and precipitating method is lower, selective floating and enriching are carried out on the precipitate to obtain the zinc concentrate; and selective size mixing and floating are carried out on the leaching residue to recover indissoluble zinc in the leaching residue and then the indissoluble zinc is sent to a lead and silver recovery system. The method has the advantages that the process is simple, and required equipment investment is less; the production cost is low to ensure that an economical treatment method is found for the zinc leaching residue with a low zinc content; roasting with coal is not needed, thus the smoke pollution problem is avoided; return water can be recycled; and floatingtailings are subjected to low-toxicity treatment, and dry stockpiling can be used for replacing full size tailings library stockpiling, therefore, potential safety hazards of the full size tailings library are eliminated.

A compound having immunosuppressive activity with low toxicity or a pharmacological salt thereof. The compound has a general formula (I) shown below or a pharmacologically acceptable salt thereof, or a pharmacologically acceptable prodrug thereof

The invention discloses a halogen-free flame retardant thermoplastic polyolefin cable material. The cable material consists of the following components in parts by weight: 0-40 parts of polyethylene resin, 20-80 parts of ethylene copolymer, 20-40 parts of compound flame retardant, 5-20 parts of compatilizer, 4-50 parts of flame retardant synergist, 1-4 parts of coupling agent, 0.5-4 parts of antioxidant and 1-10 parts of processing aid. According to the halogen-free flame retardant thermoplastic polyolefin cable material disclosed by the invention, the flame retardant is formed by compounding a borate flame retardant and a phosphorus nitrogen flame retardant; by adding a small amount of compound flame retardant, the cable material obtains a good flame retardant effect and an excellent smoke suppression effect; and the cable material has low smoke density and low toxicity index.

The invention relates to a preparation method of an organic exhaust gas micro-emulsion absorption liquid, and a method for applying the micro-emulsion absorption liquid for cleaning industrial organic exhaust gas comprising benzene, toluene, xylene, and the like. The invention belongs to the technical field of atmosphere pollution control. The absorption liquid is prepared from the components of, by mass, 80-90% of water, 0.5-3% of a surfactant, 7-19.5% of a coupling agent, and 0.02-0.06% of an auxiliary agent. The surfactant is sufficiently mixed with water, such that a surfactant solution is obtained; the auxiliary agent is dissolved in water, such that an auxiliary agent solution is obtained; the two solutions are combined and uniformly mixed; and the coupling agent is added, and the obtained solution is stirred, such that the organic exhaust gas micro-emulsion absorption liquid is obtained. The organic exhaust gas micro-emulsion absorption liquid is suitable to be used for controlling exhaust gas containing benzene-series volatiles, and has the advantages of convenient raw material source, low cost, mild and stable property, low toxicity, environment-friendliness, no absorption tower corrosion or blocking phenomena, no severe influence to human health, high removal rate to organic exhaust gas, no need of pretreatment upon exhaust gas, and low investment and running cost. Saturated absorption liquid and absorbed organics can be recycled, such that waste can be turned useful.

The invention relates to an agricultural chemical missible oil preparation with biological diesel oil dissolvent, the ingredient comprises agricultural chemical original raw pesticide, dissolvent, and emulsifying agent, wherein the dissolvent is biological diesel oil or is mixed dissolvent which is mixed by biological diesel oil and conventional agricultural chemical in any proportion. The invention uses biological diesel oil as dissolvent to replace or partially replace conventional dissolvent in the prior art, which has the advantages of high efficiency, safety, environmental protection, and low toxicity, and can reduce the cost of agricultural chemical.