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888 results about "Loading rate" patented technology
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The loading rate of an onsite system is the amount of wastewater applied to a square foot of soil per day. This rate depends on a number of factors, including the long-term acceptance rate of the soil at the infiltrative surface, the type of onsite system, and the contents of the wastewater.
Method of forming oxide layer using atomic layer deposition method and method of forming capacitor of semiconductor device using the same
In a method of forming an oxide layer using an atomic layer deposition and a method of forming a capacitor of a semiconductor device using the same, a precursor including an amino functional group is introduced onto a substrate to chemisorb a portion of the precursor on the substrate. Then, the non-chemisorbed precursor is removed. Thereafter, an oxidant is introduced onto the substrate to chemically react the chemisorbed precursor with the oxidant to form an oxide layer on the substrate. A deposition rate is fast and an oxide layer having a good deposition characteristic may be obtained. Also, a thin oxide film having a good step coverage and a decreased pattern loading rate can be formed.
Owner:SAMSUNG ELECTRONICS CO LTD
Method of forming oxide layer using atomic layer deposition method and method of forming capacitor of semiconductor device using the same
InactiveUS7151039B2Increase deposition rateImprove featuresTransistorSolid-state devicesThin oxideChemical reaction
In a method of forming an oxide layer using an atomic layer deposition and a method of forming a capacitor of a semiconductor device using the same, a precursor including an amino functional group is introduced onto a substrate to chemisorb a portion of the precursor on the substrate. Then, the non-chemisorbed precursor is removed. Thereafter, an oxidant is introduced onto the substrate to chemically react the chemisorbed precursor with the oxidant to form an oxide layer on the substrate. A deposition rate is fast and an oxide layer having a good deposition characteristic may be obtained. Also, a thin oxide film having a good step coverage and a decreased pattern loading rate can be formed.
Owner:SAMSUNG ELECTRONICS CO LTD
Pure electric motor coach communication system and method based on three CAN bus
InactiveCN101417636AAdd control nodeReduce load rateElectric/fluid circuitBus networksPower batteryLow speed
The invention provides a pure electric passenger vehicle communication system based on three ways of CAN buses, comprising a plurality of controllers and three ways of CAN buses, wherein, the CAN buses comprise three ways of CAN buses which are coupled with the plurality of controllers and consist of a CAN1 bus, a CAN2 bus, and a CAN3 bus; the CAN1 bus is a high-speed CAN bus and used for the control of a power system; the CAN2 bus is a high-speed CAN bus and used for the transmission of power battery monometer data; and the CAN3 bus is a low-speed CAN bus, provided with a plurality of vehicle body control nodes, and used for achieving the information collection and control of each part of the vehicle body. The system causes the loading rate of the power system control bus to be greatly reduced, ensures the real-time performance of the control, and improves the driving safety of the electric vehicle.
Owner:BEIJING INSTITUTE OF TECHNOLOGYGY
Concrete fracture test system and test method thereof
InactiveCN101975701ASmall loadMeet load rate requirementsMaterial strength using steady bending forcesContact pressureData acquisition
The invention relates to a concrete fracture test system and a test method thereof, and belongs to the technical field of concrete material performance test. The system comprises a measurement system and a data acquisition and processing system; a support for supporting a concrete test piece and even cushion posts symmetrically positioned on the surrounding side of the concrete test piece are arranged on a pressure tester platform of the measurement system; and springs which extend out of the tops of the cushion posts and are higher than pressure sensors are sleeved on the cushion posts. The method comprises the following steps of: when a top plate moves relative to the platform by adopting the system, making the top plate contact the springs and then contact the pressure sensors; when the top plate is contacted with the pressure sensors, controlling the load loaded onto the concrete test piece to be continuously loaded with low loading rate till the concrete test piece cracks, destabilizes and is damaged; and meanwhile, acquiring a load signal and a crack opening displacement signal and transmitting the signals to a computer. The system and the method can acquire a fine load-displacement curve so as to calculate an accurate concrete double-K fracture parameter.
Owner:胡少伟
Method and system for increasing page loading rate
ActiveCN104573025AImprove loading speedHigh speedMultiple digital computer combinationsWebsite content managementContent distributionWeb page
Owner:BEIJING JINGDONG SHANGKE INFORMATION TECH CO LTD +1
Drug delivery system and preparation method thereof
InactiveCN101485629AHigh feasibilityImprove stabilityLyophilised deliveryEmulsion deliveryOrganic solventSide effect
Owner:SHENYANG PHARMA UNIVERSITY
Prosthetic foot with energy transfer medium including variable viscosity fluid
A device prosthetic foot device with variable stiffness response includes a variable energy transfer medium disposed between first and second foot members to transfer at least some energy from the second member to the first member during use. The energy transfer medium includes a variable viscosity fluid such that the variable viscosity fluid, and thus the energy transfer medium, variably transfers energy between the first and second members to vary stiffness of the prosthetic foot device. The variable viscosity fluid can include a shear stiffening material that increases in viscosity as a load or strain, or rate of loading or rate of strain, applied, or a magneto or electro rheologic fluid responsive to a magnetic or electric field.
Owner:FREEDOM INNOVATIONS INC
Interface shearing strength test method for adhesive bonding sample of sealant and substrate
InactiveCN101509868AStrong guidanceEasy to operateUsing mechanical meansMaterial strength using steady shearing forcesHorizontal forcePositive pressure
The invention discloses a testing method of the shearing resistance between a sealing gum and a stuck sample interface of a stuck base material, which manufactures the stuck base material into two samples, and a cavity with specified size is reserved in the middle for injecting the sealing gum, thus integrating the stuck base material and the sealing gum into a whole stuck sample which is placed in the environment with the temperature of 20 DEG C minus or plus 2 DEG C and the relative humidity of 65 percent minus or plus 5 percent for being conserved for 28 days, and the samples are respectively placed into an upper shearing box and a lower shearing box, positive pressure P1 is exerted on an upper part, and horizontal force P2 is exerted simultaneously. The shearing force exerted on the samples is measured by a dynamic meter 5. The shearing force P2 is exerted with specified loading rate, and until a shearing surface between the stuck base material and the sealing gum is destroyed, and the largest force measured by the dynamic meter 5 is the shearing resistant force. The value obtained by dividing the shearing resistant force by the area of the stuck sample interface is the shearing resistance between the bonding interfaces of the stuck base material and the sealing gum under the positive pressure P1. The testing method of the shearing resistance between the sealing gum and the stuck sample interface of the stuck base material has simple operation, convenient use and favorable popularization, has no need of new additional equipments, and has strong guidance to specific industrial practices.
Owner:NORTHWEST A & F UNIV
Multi-data-channel-based data loading apparatus and method
InactiveCN105101173AImprove loading rateImprove Internet experienceConnection managementNetwork data managementLoad instructionComputer science
The invention discloses a multi-data-channel-based data loading apparatus and method. The apparatus comprises a thread establishment module for establishing at least two loaded data threads according to a data loading instruction, a thread distribution module for distributing the threads to at least two data channels, and a data downloading module for establishing a transmission link by corresponding data channels based on all threads and downloading the data according all the transmission links. According to the method and apparatus, multiple threads are established and are distributed to two or more data channels, and multiple transmission links are established by the corresponding data channels based on the threads; and the same data are downloaded in a blocking mode by using the transmission links of the two or more data channels. Therefore, the data loading rate is substantially improved and the networking experience is enhanced.
Owner:NUBIA TECHNOLOGY CO LTD
Method for preparing environment-responsive mesoporous silicon nanoparticles
InactiveCN102380102ALow priceEasy to operatePowder deliveryOrganic active ingredientsBiocompatibility TestingSelf-assembly
The invention relates to a method for preparing environment-responsive mesoporous silicon nanoparticles. The mesoporous silicon nanoparticles with the particle size of 20 to 1,000nm, the pore size of 2 to 50nm, the specific surface area of 500 to 1,500m<2> / g and a controlled structure are prepared by a template extraction method and subjected to surface functionalization by a self-assembly technology. A medicine sustained-release system prepared by the method is high in biocompatibility and medicine loading rate, can be released intelligently and controllably and has good application prospects in fields of growth factor and gene release, enzyme immobilization, cancer treatment and the like in tissue engineering, the preparation method is simple, reaction conditions are mild, and experiment raw materials are low in cost.
Owner:DONGHUA UNIV
Medical wound dressing with anti-bacterial nanometer particulate
InactiveCN101224310AGood water vapor transmission rateImprove water absorptionAbsorbent padsBandagesParticulatesWound dressing
The invention discloses a medical wound dressing which is loaded with antibiotic nanometer particles and which is in a spongy state when being dried and in a gel state after absorbing the moisture; the medical wound dressing is fixed in a spongy membrane prepared by chitosan and natural high molecular polymers and derivatives of the chitosan with the proportion of 10 to 19 percent of the spongy membrane and natural polymers by drug-loading nanometer particles; the drug-loading nanometer particles contains antibiotics with the particle size of 100nm to 1000nm, the encapsulation rate of 50 to 98 percent and the drug-loading rate of 5 to 60 percent and the weight percentage of 2 to 10 percent of the drug-loading nanometer particles in the wounding dressing. Combing the sustained and controlled release characteristic and the advantage of polysaccharide membrane, the invention has high water absorbability, air permeability, moisture permeability and good biological compatibility can keep the wound physiological moisture environment and promote the wound to recover and has hemostatic effect; at the same time, the invention has good slow release performance for the antibiotics, can prevent the infection of the wound and accelerate the recovery, thus being suitable for a plurality of wounds such as the traumas, burns and ulcers.
Owner:FOURTH MILITARY MEDICAL UNIVERSITY
A kind of curcumin nano-micelle preparation and preparation method thereof
InactiveCN102274163AImprove bioavailabilityImprove stabilityPharmaceutical delivery mechanismKetone active ingredientsSolubilityEvaporation
The invention relates to a curcumin nano micelle preparation and a preparation method thereof. The preparation consists of curcumin and amphiphilic block copolymer. The preparation method comprises the following steps of: jointly dissolving the curcumin and the amphiphilic block copolymer in an organic solvent, performing rotary evaporation to remove the organic solvent, performing vacuum drying on the obtained a medicine-containing film, sanding overnight, removing residual organic solvent, adding an aqueous phase, combining ultrasonic dispersion and 35-38 DEG C thermostatic oscillation to obtain a micelle solution, centrifuging at a high speed, and taking supernate, namely the curcumin nano micelle preparation. The curcumin nano micelle preparation is prepared by an improved film dispersion method, the solubility of the curcumin in water is improved, the loading rate of the preparation can reach 8 percent, the micelle particle size is less than 100nm, and the curcumin nano micelle preparation has the advantages of stable structure, small particle size, low toxicity, high safety, long in-vivo circulation time, simple storage and the like.
Owner:SHANDONG UNIV
Method and apparatus for load rate monitoring
InactiveUS6957166B1Inflated body pressure measurementFluid pressure measurement by electric/magnetic elementsMicrocontrollerDisplay device
A system for real-time monitoring of the dynamic loading rate on support systems used in underground mines and other situations is provided. The load rate monitoring apparatus uses a programmable microcontroller to monitor and calculate the loading rates on the support system from pressure transducers or welded strain gauge instrumentation installed on the support systems. The apparatus is programmed to sequentially activate different color lights and / or audio alarms as the loading rate increases on the support systems. The apparatus is intended for installation with numerous underground support systems used in underground mining to alert miners of dangerous loading conditions, which support systems include longwall shields, mobile roof support (MRS) machines, hydraulic jacks, rock bolts, steel sets, and roof trusses. Intrinsically safe hand-held computers and displays may be used for programming the microcontroller subsystem and optimal load weight indicators include multicolor strobes, light-emitting diodes (LEDs), fluorescent visual indicators and audio alarms.
Owner:GOVERNMENT OF THE UNITED STATES OF AMERICA THE AS REPRESENTED BY THE SEC OF THE DEPT OF HEALTH & HUMAN SERVICES CENT FOR DISEASE CONTROL & PREVENTION
Honeycomb integral type low temperature denitrifying catalyst and preparation method thereof
ActiveCN105727985AImprove denitrification activityDenitrification suitableHeterogenous catalyst chemical elementsDispersed particle separationNickel saltCerium
The invention discloses a honeycomb integral type low temperature denitrifying catalyst and a preparation method thereof. The preparation method comprises the following specific steps: 1) dissolving ferric sat or cobalt salt or copper salt or nickel salt and manganous salt or cerium salt in water to form a metallic salt solution; 2) soaking titanium dioxide in the metallic salt solution to form suspension, using an impregnation method or coprecipitation method or hydrothermal method to prepare the suspension into catalyst active components; 3) mixing the catalyst active components with the inorganic binding agent, the organic polymer solution, the surfactant and water, stirring to form a slurry; 4) coating the slurry on a honeycomb cordierite carrier; and 5) drying the coated honeycomb cordierite carrier, and calcining, to obtain the honeycomb integral type low temperature denitrifying catalyst. The active components of the catalyst obtained through the preparation method of the invention are high in loading rate on the carrier, the coating and the carrier are firmly bound, and the low temperature denitrifying activity is high.
Owner:CHINA BUILDING MATERIALS ACAD
Method for optimal multi-vehicle dispatch and system for the same
ActiveUS20070194912A1Increase in delivery timeIncrease in consolidation costData processing applicationsRadio/inductive link selection arrangementsTransport timeTransport engineering
A vehicle dispatch system enables optimal dispatch of a plurality of vehicles with information of available vehicles from transportation company terminals and information of orders from client terminals under restrictive conditions such as vehicle sizes, minimum loading rates, and a maximum number of assignment locations, based on transportation regions preset in consideration of transportation times, past order quantities, and order congestion degrees, such that a relevant vehicle can perform delivery of freight within a predetermined transportation region to minimize a total transportation cost for each transportation region. The system minimizes a delivery distance of each vehicle, increases a loading volume of the vehicle to reduce an empty rate of vehicles, and minimizes the number of dispatched vehicles, thereby reducing the total transportation cost.
Owner:LG CHEM LTD
Acid amide-grafted sodium alginate nanometer material, preparation method thereof and use thereof
InactiveCN101565469APromote degradationGood biocompatibilityPharmaceutical non-active ingredientsCarrier-bound/immobilised peptidesChemical synthesisCrystallography
The invention relates to an acid amide-grafted sodium alginate nanometer material, a preparation method thereof and use thereof. The acid amide-grafted sodium alginate nanometer material comprises acid amide having an aliphatic chain and sodium alginate having a molecular weight of less than or equal to 50,000, and is characterized in that a carboxyl group of the sodium alginate is grated with hydrophobic acid amide by a chemical synthesis method for hydrophobic modification so as to form an amphipathic material, namely a modified sodium alginate nanometer material, having both hydrophobicity and hydrophilcity. The acid amide-grafted sodium alginate nanometer material performs self aggregation in deionized water to form nanoparticles, wherein the diameter of the nanoparticles is between 40 and 1,000 nanometers; under a condition of substituted ratio of 2 percent, the mean particle diameter of the nanoparticles is 596.2 nanometers; the medicament-loading rate is up to 40 percent; the medicament entrapment rate is up to 95.1 percent; and the medicament release time is as long as 6 days. The acid amide-grafted sodium alginate nanometer material can be used in a plurality of pharmaceutical fields as a slow release carrier of a plurality of medicaments, particularly hydrophobic medicaments, protein medicaments, polypeptides and vaccines.
Owner:OCEAN UNIV OF CHINA
Vehicle pooling method of freight vehicle-pooling platform
The invention discloses a vehicle pooling method of a freight vehicle-pooling platform. The method comprises the following steps: 1) carrying out freight owner vehicle-pooling information issuing and checking; 2) extracting freight owner vehicle-pooling information on the platform and carrying out classification on the freight owner vehicle-pooling information; 3) dividing each piece of vehicle-pooling information into fixed information and floating information; 4) extracting vehicle owner information from a platform database and carrying out classification on the information; 5) dividing each piece of vehicle owner information into fixed information and floating information; 6) intelligently matching an appropriate vehicle-pooling freight owner according to the fixed information and the floating information in the vehicle-pooling information and determining an optimal vehicle-pooling scheme; 7) intelligently pushing to the vehicle-pooling scheme determined in the step 6) to a vehicle owner meeting screening conditions; 8) calculating vehicle-pooling cost of each freight owner; and 9) if vehicle-pooling is successful, starting vehicle pooling. The method not only can ensure efficient vehicle pooling and save transport cost of each freight owner, but also can improve loading rate of each driver.
Owner:NANJING UNIV
Organic bentonite pesticide sustained-release granular formulation and preparation method thereof
InactiveCN102578081AGood compatibilityDoes not constitute pollutionBiocideFungicidesChemical structureControl release
The invention relates to a sustained-release granular formulation for preventing and treating crop diseases and insect pests and a preparation method thereof. The pesticide sustained-release granular formulation comprises bentonite, an organic modifier, pesticide active ingredients, an inert filler and a binding agent, and is prepared by the preparation method comprising the steps of: (1) with the bentonite as a basic material, modifying the bentonite by the organic modifier to obtain organic bentonite; (2) loading the pesticide active ingredients on the organic bentonite to prepare medicine-carrying organic bentonite; and (3) mixing the medicine-carrying organic bentonite, the inert filler and the binding agent proportionally, and pelleting to obtain the sustained-release granular formulation. The preparation method of the sustained-release granular formulation, provided by the invention, not only overcomes the defect of low pesticide loading rate of the natural bentonite, but also realizes the controlled release of the pesticide by adjusting a chemical structure and the amount of the modifier, so that the sustained-release granular formulation is coincident with an occurrence rule of the plant diseases and insect pests, and the pesticide sustained-release granular formulation is used safely, reasonably, economically and effectively.
Owner:GAUNGXI TIANYUAN BIOCHEM +1
Preparation method of nanometer graphene oxide carrier for photodynamic therapy
InactiveCN102370980AHigh load rateGood treatment effectPowder deliveryEnergy modified materialsCancer cellTherapeutic effect
The invention relates to a preparation method of a nanometer graphene oxide carrier for the photodynamic therapy. The method is characterized in that: the surface of nanometer graphene oxide, which is modified by a hydrophilic polymer, loads a hydrophobic photosensitizer containing a large pi-conjugated structure through the pi-pi accumulation and the hydrophobic-hydrophobic interaction, so a product for the photodynamic therapy is obtained. Compared with the prior art, the photosensitizer loading rate of the nanometer graphene oxide carrier, which is high to 14 wt%, is higher than the photosensitizer loading rate of other photosensitizer carriers, such as a polymer micelle, a liposome, a liposome, a nanometer silicon ball and the like, so the nanometer graphene oxide carrier which can be applied to the photodynamic therapy has a good treatment effect, and has an obvious inhibitive ability on the growth of cancer cells under the irradiation of near infrared light, so a novel high efficiency loading photosensitizer system is provided for the treatment of cancers of tumors at shallow skin surfaces.
Owner:TONGJI UNIV
True triaxial test method for simulating shearing type rock burst
InactiveCN106442174APowerful testGet Deformation PropertiesMaterial strength using steady shearing forcesTriaxial shear testStress conditions
The invention discloses a true triaxial test method for simulating shearing type rock burst. In the method, a true triaxial loading path and boundary condition characterized in that a single surface is free and five surfaces are stressed is adopted, a test piece with a large size is adopted, a certain three-dimensional load is applied, a loading rate of one direction is controlled, and a cuboid rock sample of which the single side is free under a three-dimensional compression stress state is used for simulating a special mechanical behavior of a field surrounding rock representativeness rock unit in a tangential stress centralization process. When the method is adopted, an inoculation and generation overall process of the shearing type rock burst can reappear in a laboratory, the problem that a traditional indoor test method cannot reasonably simulate the shearing type rock burst under a complex stress condition is solved, and the true triaxial test method has important practical significance and academic value for the mechanism and prediction studies of the type of rock burst.
Owner:GUANGXI UNIV
8-analogue-shaped soil uniaxial tensile tester
InactiveCN102901669AComplete tensile stress-strain curveImprove test repeatabilityMaterial strength using tensile/compressive forcesSoil scienceStructural engineering
The invention discloses an 8-analogue-shaped soil uniaxial tensile tester comprising a main platform, a loading system, a measuring system, and a sample positioned drawing system. The tester is characterized in that the loading system, the measuring system, and the sample positioned drawing system are all arranged on the main platform; an 8-analogue-shaped sample is prepared through an 8-analogue-shaped sample-pressing mold and an 8-analogue-shaped sample-pressing piston; and during testing, the 8-analogue-shaped sample is drawn in an 8-analogue-shaped retractor. The tester provided by the invention adopts strain-controlled loading. Compared with a traditional uniaxial tensile tester, a complete soil tensile stress-strain curve can be obtained, and the influence of loading rates on soil tensile properties can be analyzed. According to the invention, the 8-analogue-shaped retractor is used for drawing the 8-analogue-shaped sample, and no auxiliary fixture is needed. Sample breakpoint position and fracture surface area are fixed, and test repeatability is good. According to the invention, the sample is prepared by full-area pressing by using the 8-analogue-shaped mold and piston, such that stresses on various parts of the sample are uniform, no artificial weak surface exists on a drawing direction, and testing precision is improved. The tester has the advantages of simple structure, simple operation, low cost, and reliable data.
Owner:SUZHOU NANZEE SENSING TECH
Commodity distribution path planning method based on MoCD algorithm
The invention relates to a commodity distribution path planning method based on an MoCD algorithm (multi-object constraint algorithm based on Dijkstra algorithm), which includes the following steps of: firstly taking intersections or endpoints of roads as nodes and building a model of an urban road network according to actual urban road conditions; secondly determining commodity price information, and screening manufacturers which accord with commodity sending destinations; then selecting the manufacturers according to the required commodity number and the manufacturer stock quantity, and a supply and demand scheme which has multiple manufacturer combinations so as to satisfy required commodity quantity existing; and finally planning an optimal path by using the Dijkstra algorithm based on manufacture geographic positions and vehicle positions determined in the last step, and using a step by step search method to improve the search efficiency of the invention algorithm. The transport cost is saved, and the vehicle loading rate and the distribution efficiency are improved by planning the optimal path.
Owner:吕建正
Motive power monitoring and warning method of rock mass landslide
InactiveCN103198619AAvoid complexityStability Unified Instability CriterionAlarmsIn situ soil foundationInstabilityLandslide
The invention relates to a method of detecting stability of a rock mass side slope and warning and forecasting instability of the side slope by adopting motive power increment displacement response ratio parameters. A motive power monitoring and warning method of rock mass landslide includes the following steps: (1) ensuring side slope geometric elements to be detected, mapping of a sliding surface and self weight of a landslide body, (2) designing and arranging side slope downward sliding motive power and displacement monitoring points, (3) monitoring and ensuring the side slope downward sliding motive power and downward sliding displacement response, (4) ensuring side slope downward sliding motive power loading rate parameters, (5) ensuring side slope downward sliding displacement response rate parameters, (6) ensuring landslide motive power increment displacement response rate parameters, (7) ensuring a landslide stability motive power increment displacement response rate criterion, and (8) monitoring side slope stability and monitoring and early warning. Stability coefficients of a limit equilibrium method are organically coupled with a displacement timing sequence analytic method and characteristics of displacement predictive parameters, and limitations of a traditional method are overcome.
Owner:QINGDAO TECHNOLOGICAL UNIVERSITY
Method for testing brittle material dynamic-shear fracture toughness and implementation device thereof
InactiveCN104048883AAchieving dynamic stress balanceTest accurateMaterial strength using steady shearing forcesEngineeringStrain gauge
The invention discloses a method for testing brittle material dynamic-shear fracture toughness and an implementation device thereof. The method comprises the following steps of installing a cylindrical sample with annular precracks on a Hopkins pressure lever dynamic experiment device, applying a dynamic shear force for two ends of the cylindrical sample with the annular precracks arranged between an incident bar and a transmission bar by impacting the incident bar by an impact pellet, and calculating dynamic-shear fracture toughness KIIC of the brittle material and a corresponding loading rate by a strain value, incident bar and transmission bar cross sectional areas, pressure lever elasticity modulus and sample confining pressure value according to a formula provided by the invention. The method can acquire dynamic-shear fracture toughness of a quasi-brittle material and fills in gap of the research field.
Owner:SICHUAN UNIV
Method for preparing natural material inorganic nanoparticle composite nano-fiber through electrostatic spinning
InactiveCN102787382ALow priceEasy to operateMonocomponent protein artificial filamentFilament/thread formingFiberFreeze-drying
The invention relates to a method for preparing natural material inorganic nanoparticle composite nano-fiber through electrostatic spinning, which comprises steps that a template is added into diluted aqueous alkali, the mixture is heated to 80-90 DEG C through an oil bath, mixed for 1-10 hours, gradually added with tetraethyl orthosilicate, centrifugally washed by deionized water and absolute ethyl alcohol sequentially, and dried and reflowed in HCL-ethanol mixed liquor to remove the template, so freeze dried mesoporous silicon is obtained; and natural materials are dissolved in the solvent to prepare the natural material solution, the mesoporous silicon is added into the natural material solution for electrostatic spinning, fumigating and crosslinking are carried out for 0-48 hours, so the natural material mesoporous silicon composite nano-fiber is obtained. The natural material inorganic nanoparticle composite nano-fiber which is prepared by the method has good biocompatibility, a simple preparation method and moderate reaction conditions, is low in experimental raw material price, has high drug-loading rate, can be controlled to be released for a long term, and can be applied in the biomedicine and tissue regeneration fields of growth factor and gene release of tissue engineering, cancer treatment and the like.
Owner:DONGHUA UNIV
Surface defect form and depth on-line lossless detection method of high-temperature continuous casting blank
InactiveCN101655464ASuppress interferenceEnable digital assessmentMaterial analysis by optical meansUsing optical meansMetallurgyQuality assessment
The invention relates to a surface defect form and depth on-line lossless detection method of a high-temperature continuous casting blank, comprising the following steps: scanning the surface distanceof the transverse direction of the high-temperature continuous casting blank along a pulling-speed direction of the casting blank; measuring distance two-dimensional lattices on the running directionand the transverse direction of the casting blank; converting the distance two-dimensional lattices into a distance dimensional HSB two-dimensional diagram; and finally processing the HSB two-dimensional diagram to recognize the forms of surface defects and calculate the depths of the defects in a quantization mode. The method can effectively inhibit the interference of non-defect oxidative sheetiron in a defect form, realize the surface defect form and depth on-line detection of the continuous casting blank above 950 DEG C and evaluate the quality of the surface defects of the integral high-temperature continuous casting blank. The surface defect form and depth on-line lossless detection method has significances for increasing the automatic level of the surface detect detection of the high-temperature continuous casting blank, reducing the production cost, increasing the direct rolling and heat transmitting and loading rate of the continuous casting blank and has important guiding functions for developing a continuous casting blank quality forecast system, improving a continuous casting process technology and increasing the casting blank quality.
Owner:CHONGQING UNIV
Preparation method and application of medicament-cyclodextrin inclusion compound self-emulsifying composition
InactiveCN102106819AGood slow releasePharmaceutical non-active ingredientsEmulsion deliveryOil phaseWater soluble drug
The invention discloses a preparation method and application of a medicament-cyclodextrin inclusion compound self-emulsifying composition. The composition is prepared through the following steps: preparing a medicament-cyclodextrin inclusion compound by combining a medicament and cyclodextrin; mixing the medicament-cyclodextrin inclusion compound, an oil phase, an emulsifier, an assistant emulsifier, a stabilizer and an additive; and completely dissolving the materials through magnetic stirring or ultrasonic; and uniformly mixing. The composition has the advantages that the defects of low solubility of poorly water-soluble drugs, low bioavailability, low drug-loading rate and the like are overcome, the medicament stability is greatly improved, the problems of poor emulsifier stability, large storage volume and the like caused by a water phase are solved, and the effect of sustaining medicament release can be achieved. The preparation method has the advantages of simplicity, developed process, high yield of the composition and suitability for industrial production.
Owner:CHINA PHARM UNIV
Amphiphilic prodrug of 7- ethyl-10-hydroxycamptothecin and preparation method thereof
InactiveCN102060991AControl release speedPromote degradationOrganic chemistryPharmaceutical delivery mechanismSolubility7-ethyl-10-hydroxycamptothecin
The invention discloses an amphiphilic prodrug of 7- ethyl-10-hydroxycamptothecin, which is prepared by connecting hydroxyl at the site 10 and / or 20 site of the 7-ethyl-10- hydroxycamptothecin and a hydrophilic group through a scissionable chemical bond. The amphiphilic prodrug is self-assembled in water to form a micelle or vesicle structure. Therefore, on one hand, the solubility of SN-38 in water is greatly increased, and the stability of SN-38 lactone rings is improved; and on the other hand, the drug loading rate is high and the SN-38 can be quickly released in cells, consequently the defect of low drug loading rate of traditional drugs is overcame. Moreover, with the nano-micelles or the nano-vesicles of the prodrug, EPR (enhanced permeability and retention) effect targeted cancer tissues of tumors can be effectively utilized.
Owner:ZHEJIANG UNIV
Abamectin microcapsule powder prepared from lignin-based wall material and method for preparing abamectin microcapsule powder by use of lignin-based wall material
ActiveCN105010362ATo achieve the effect of encapsulating pesticidesPH responsiveBiocideAnimal repellantsCross-linkAbamectin
The invention discloses abamectin microcapsule powder prepared from a lignin-based wall material and a method for preparing the abamectin microcapsule powder by use of the lignin-based wall material. The method comprises the following steps: dissolving a purified amido sodium lignosulfonate wall material and an emulsifying agent in water so as to prepare an aqueous solution to obtain a water phase; dissolving an abamectin tech in an organic solvent to obtain an organic phase; uniformly adding the organic phase into the water phase under a rotating condition, and then shearing; and then regulating the pH value of a dispersion liquid and performing a complex coacervation reaction; cooling, adding a cross-linking agent for a cross linking reaction, performing centrifugal separation, filtering and drying to obtain the microcapsule powder. The preparation process of the abamectin microcapsule powder is simple, the wall material is environmentally friendly and degradable, and abamectin tech photolysis can be prevented; the prepared microcapsule is relatively high in drug-loading rate and entrapment rate and obvious in slow release effect, and regulation and control on release can be realized within a certain pH range.
Owner:SOUTH CHINA UNIV OF TECH
Preparation and application of insoluble drug-entrapped poloxamer/amphiphilic polysaccharide mixed micelle
InactiveCN102626518AOvercome the problems of high critical micelle concentration and low drug loadingImprove oral bioavailabilityPharmaceutical delivery mechanismPharmaceutical non-active ingredientsMixed micelleCytochrome p450 enzyme
The invention discloses preparation and application of an insoluble drug-entrapped poloxamer / amphiphilic polysaccharide mixed micelle. The insoluble drug-entrapped poloxamer / amphiphilic polysaccharide mixed micelle is prepared through a dialysis method or a solvent evaporation method. The mixed micelle is low in critical micelle concentration, is high in drug-loading rate, is capable of obviously prolonging the stabilization time and has the long-circulation function of a nanomicelle and has dual functions of restraining the metabolism of P-glycoprotein and cytochrome P450 enzyme and is capable of increasing the bioavailability of oral administration. The mixed micelle is simple in preparation method, is mature in process and is high in yield and can be prepared into preparations for the oral administration, such as tablets, capsules, pills and syrups.
Owner:CHINA PHARM UNIV
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