The invention discloses a method for cultivating wood-rotting fungi. The raw materials for cultivating the wood-rotting fungi comprise the following components of: 45-55 parts of cotton stalk crumb, 8-20 parts of fine sawdust, 8-20 parts of corncob, 5-20 parts of bran coat, 4-7 parts of bean dregs, 5-11 parts of pure chicken manure, 0.5-1.5 parts of phosphate fertilizer, 0.5-1.5 parts of plaster, 1-5 parts of lime and 8-20 parts of cotton seed hull. The raw materials in weigh ratio are cultivated to generate the wood-rotting fungi according to the steps of adding water in the raw materials and uniformly stirring, building pile and fermenting, producing an inoculation bacterial bag and generating mushroom. According to the method disclosed by the invention, the consumption of the cotton seed hull is reduced; and cotton straws are used to replace the cotton seed hulls and are simultaneously matched with the fine sawdust and the corncob to produce a cultivation raw material of the wood-rotting fungi. The method has the characteristics of ensuring quick material consumption by hypha during fingi fermentation, robust growth and white and density, compact produced fruiting body and rounding mushroom shape. According to the method, the labor and time are saved, the cost is reduced and the yield is increased.