1107 results about "Anti stress" patented technology

Stress-related nucleic acid molecules and polypeptides and fragments and variants thereof are disclosed in the current invention. In addition, stress-related fusion proteins, antigenic peptides, and anti-stress-related antibodies are encompassed. The invention also provides recombinant expression vectors containing a nucleic acid molecule of the invention and host cells into which the expression vectors have been introduced. Methods for producing the polypeptides and methods of use for the polypeptides of the invention are further disclosed.

The invention provides a cow feedstuff combination, in particular to a functional feedstuff combination to feed high production cow. The invention endows fatty acid with function of rumen passing by adding strong alkali week acid salt fatty acid salt, to act as energy supplement agent for cow; the combination is matched with other protein feedstuff, energy feedstuff, mineral, Vitamin and so on to acquire a fine mixture, which can meet the special requirement of such components as energy, protein, Vitamin and mineral and so on of cow, in particular to high production cow 100 days after delivery, and release the energy balance, improve the body condition, milk quality and anti-stress, and prevent the occurrence of nutrition metabolization diseases.

The invention discloses an anti-stress health compound feed for jewfish. The feed consists of an animal protein source, a plant protein source, a fat source raw material, a sugar source raw material, composite vitamin, composite mineral salt, hepatinica, a Chinese herbal medicine compound preparation, probiotic powder, a composite immunopotentiator, antimicrobial peptide, an acidifying agent and a premixed compound additive, wherein the animal protein source comprises one or more of fish meal, euphausiid meal and chicken meat meal; the plant protein source comprises one or more of seaweed meal, fermented soybean meal, soy protein concentrate and corn protein powder; the fat source comprises one or more of soybean oil, fish oil and phosphatide oil. The feed disclosed by the invention has the characteristics of being rapid in growth, low in food coefficient, good in stability in water, rapid to eat, convenient to use, low in feeding cost, resistant to stress, healthy and the like.

The invention discloses a feed additive and a preparation craft, in particular to a green feed additive for layers and the preparation craft, which is prepared by the mixure of Chinese medicine chemical additive, micro ecology preparation, Vitamin class, trace elements, methionine, chlorination choline, ethoxybenzoylaminoquinoline, rice husk powder and zeolite. The invention has the advantages of nontoxic side effect, no residue, no antibiotic nature, improvement of the laying intensity of layers and the quality of eggs, and enhancement of organism immunity and the anti-stress ability of the organic body.

The invention provides an anti-stress fermentation protein feed which is produced by composite bacterium inoculation and high-temperature and moderate-temperature fermentation of a plant derived protein raw material, a terrestrial animal derived protein raw material and a marine animal derived protein raw material. Macromolecular substances in the protein feed are digested and decomposed into micromolecular substances, stressors in nutritional ingredients are decreased, anti-stress active factors such as genistein, glutathione and glucosamine are increased, the immunity of fed animals is improved, and the protein feed shows a good anti-stress capability. The invention further provides a producing method of the anti-stress fermentation protein feed. The feed product with high functionality, good anti-stress effect and high economical efficiency is obtained with the adoption of the multiple derived protein raw materials, a specific formula and an appropriate matching ratio and by mixed fermentation through a special secondary fermentation process.

The invention provides a high efficiency livestock and poultry nutrition replenisher and a preparation method thereof, and the nutrition replenisher contains various vitamins, amino acids and electrolyte. Simultaneously, the multi-stage premixing process is adopted by the high efficiency livestock and poultry nutrition replenisher, so that the high mixing uniformity of ultra-trace elements can beensured; and furthermore, sanguinarine is introduced into drinking water nutrition replenisher and is processed by peridium treatment, and emulsification treatment is carried out on liposoluble vitamins, so that good water-solubility can be guaranteed. The high efficiency livestock and poultry nutrition replenisher has comprehensive nutrition, leads all nutrient components to be supplemented witheach other, can effectively prevent deficiency of the vitamins and the amino acids, maintains electrolyte balance, regulates the metabolism of organism, improves the feed conversion rate and the anti-stress capability, stimulates the immune function, reduces the occurrence of diseases, and has remarkable economic and social benefits as well as broad market prospect.

The invention relates to a marine-fish environmental protective compound feed, consisting of the following materials in weight ratio: 13 to 20 portions of domestic fish powder, 8 to 15 portions of biological fish meal ABP600, 8 to 12 portions of soybean meal, 10 to 18 portions of peanut bran, 3 to 10 portions of corn, 3 to 7 portions of cotton seed meal, 3 to 7 portions of rapeseeds meal, 3 to 5 portions of meat and bone meal, 3 to 5 portionsof squid bowels powder, 20 to 30 portions of high gluten flour, 1.0 to 3.0 portions of blood meal, 1.0 to 2.0 portions of soybean lecithin, 2.0 to 3.0 portions of marine-fish oil, 0.3 to 0.6 portions of choline chloride (50%), 0.05 to 0.1 portions of Vitamin C phosphate (35%), 0.15 to 1.5 portions of calcium biphosphate, 0.2 to 0.5 portions of compound multiplex vitamin, 0.5 to 1.5 portions of compound mineral salt, 0.1 to 0.3 portions of feed attractant, 0.1 to 0.3 portions of micro-bio-preparation, 0.03 to 0.08 portions of A3Alpha peptidoglycan, 0.01 to 0.04 portions of phytase, and 0.04 to 0.08 portions of non-starch polysaccharase. The compound foodstuff can meet the nutrition demands of such high density cultivated marine fishes such as weever, large yellow croaker, American red fish, sparidae fishes, and trachinotus ovatus and rudd etc, and the cultivated objects can rapidly grow and has high foodstuff conversion rate; the compound foodstuff can intensify the immunity and anti-stress ability of fishes and endow them with good vitality, vivid body color and high survival rate; compared with marine fished cultivated by other foodstuffs, the excretion rates of nitrogen and phosphorous of the marine fishes cultivated by the compound foodstuffs is lowered by 10 to 15 percent, and cause smaller contamination to the cultivation water body.

The invention discloses an anti-stress anti-diarrhea growth-promotion Chinese herbal medicine feed additive for a weaned pig, which is obtained by carrying out the superfine grinding and mixing on the following components at the mass ratio: 1-5 parts of Astragalus mongholicus, 1 part of Scutellaria baicalensis, 1 part of malt, 1 part of liquorice, 1-5 parts of dangshen, 1-5 parts of poria cocos and 1-5 parts of largehead atractylodes rhizome. According to the Chinese herbal medicine feed additive disclosed by the invention, the weaned pig growth performance can be improved, and the Chinese herbal medicine feed additive has the anti-diarrhea effect; the gastrointestinal tract development of the weaned pig can be promoted; the activity of the digestive enzyme of the gastrointestinal digestive tract of the wigged pig can be improved to promote the development of the pig digestive enzyme system; the micro-ecological environment of the digestive tract of the pig can be regulated and stabilized to accelerate the pig to grow; the antioxidation function of the wigged pig organism can be improved so as to improve the compensatory capability of the wigged pig organism on external irradiation; the intestinal mucosa form of the wigged pig can be improved so as to alleviate the intestinal villus withering of the wigged pig and promote the tract of the wigged pig to restore; and the immunologic function of the intestinal mucosa of the wigged pig can be regulated.

The invention relates to a constant-load stress corrosion evaluation method and a constant-load stress corrosion evaluation device of a small test sample. The essentials are as follows: the constant-load stress corrosion testing method and device can be used for testing an anti-stress corrosion cracking property of a thin-wall pipe and a small-size member; the small-size test sample is designed and processed and the level of the loaded stretching stress is accurately controlled; a stress corrosion experiment is carried out in an acidic environment; an anti-sulfide stress corrosion performance and an acting mechanism of the thin-wall pipe and the small-size member in the acidic corrosion environment are evaluated and researched according to an experiment result. With the adoption of the evaluation method and device, the anti-stress corrosion cracking property of the thin-wall pipe and the small-size member, which can not be used for processing a standard test sample, can be determined; the applicability of the material of the member can be obtained according to a testing result, so that the material selection and the applicability evaluation of the thin-wall pipe and the small-size member are carried out.

The present invention relates to a method for breeding chick of environment-friendly chick feed. According to the method, the worry about residues of antibiotics can be eliminated to improve the trust of consumers. In addition, the compost produced by chickens produced by feeding the non-antibiotic feed has good quality, and the environment will not be polluted because the critter manure with residual antibiotic will not be discharged. The invention provides an environment-friendly chick feed made by mixing Chinese medicinal materials without any antibiotic, simultaneously supplies the environment-friendly chick feed all together with anti-stress agents, digestive agents, high-content nutritional agents, vitamins, and garlic extracts. In addition, a circs for chicken maintenance, a circs that chick indicating symptoms of influenza, a circs of lowered immunity caused by bacilli diseases, and a circs of diarrhea due to bad digestion or enteritis are divided, and then suitable feeds are respectively supplied.

The invention discloses anti-stress feed additives. The compositions of the anti-stress feed additives are: 15 to 30 percent of astragalus polysaccharides, 15 to 30 percent of radix scutellariae glucoside, 10 to 20 percent of pennyroyal wrappage, 10 to 20 percent of honeysuckle extract, 0.5 to 5 percent of vitamin C, 0.5 to 5 percent of vitamin E, 0.001 to 0.02 percent of chromium picolinate, 0.05 to 0.3 percent of zinc oxide, 0.1 to 1 percent of arginine, 1 to 5 percent of tryptophan, 1 to 5 percent of glutamine, 1 to 5 percent of sodium sulfate, 1 to 3 percent of calcium iodate, 1 to 3 percent of sodium selenite, 1 to 3 percent of potassium dihydrogen phosphate, the balance being auxiliary materials. The anti-stress feed additives are added into poultry feed according to the ratio of 0.1 to 0.3 percent. The anti-stress feed additives have the advantages that: firstly, the anti-stress feed additives can reinforce the anti-stress capability of poultry, and are particularly suitable for reinforcing the cold stress capability and the heat stress capability; secondly, the anti-stress feed additives can quickly replenish electrolyte loss caused by dehydration, and quickly recover the osmotic pressure of cells and adjust the acid-base balance in the body; and thirdly, the anti-stress feed additives can reinforce the anti-positioning capability of water bodies of the aquatic animals.

The invention discloses a Chinese herbal medicine composite probiotics feed additive for pigs and a preparation method of the Chinese herbal medicine composite probiotics feed additive. The Chinese herbal medicine composite probiotics feed additive for the pigs consists of a composite Chinese herbal medicine fermentation material, bacillus, saccharomycetes and lactic acid bacteria. The composite Chinese herbal medicine fermentation material comprises the following ingredients in parts by weight: 5-6 parts of Astragalus membranaceus, 2-3 parts of honeysuckle, 1-2 parts of bean pulp and 1-2 parts of bran. The quantity ratio of the bacillus to the lactic acid bacteria to the saccharomycetes is (6-5):(4-3):(2-1), and the total amount of viable bacteria in each gram of product is more than 2.0*109. Chinese herbal medicines are used as fermentation substrates, and three kinds of probiotics are added to perform fermentation, and therefore, the additive contains the effective constituents of the Chinese herbal medicines and the probiotics are enhanced. The Chinese herbal medicine composite probiotics feed additive for the pigs adjusts the microecological balance of the pig intestines, reduces the intestines problems, promotes the growth, enhance the anti-stress capability and immunity of the pigs, reduces the feed conversion ratio, improves the quality of meat, reduces the foul smell of faeces, improves the breeding environment and increases the economic benefits of pig raising.

The invention provides a feeding combination for brooding layers before six-week old, which includes a feeding I for layers before two-week old and a feeding II for layers between three to six-week old, wherein the feeding I comprises corn, puffed grains, puffed soybean meal, puffed soybeans, fermented soybean meal, insect protein, one level steam fish meal, plant oil, monosaccharide or disaccharides, calcium hydrogen phosphate, limestone powder, baking soda, compound trace elements, amino acid, choline chloride, salt, anti-stress agent, multi-vitamin, compound enzyme preparation and phytase raw materials; and the feeding II comprises corn, soybean meal, fermented soybean meal, puffed soybeans, insect protein, one level steam fish meal, plant oil, monosaccharide or disaccharides, calcium hydrogen phosphate, limestone powder, baking soda, compound trace elements, amino acid, choline chloride, salt, anti-stress agent, multi-vitamin, compound enzyme preparation and phytase. Compared with the existing layer feeding, the phase combination feeding is more reasonable and scientific, and the immunity and the survive rate of layers are obviously improved and the morbidity is obviously decreased.

The invention relates to a method for preparing an anti-stress agent used for fishing, belonging to the technical field of aquatic product compound feed. The method is characterized in that glutamine dipeptide, rhubarb extract, vitamin C, vitamin E, potassium chloride, sodium chloride, anhydrous dextrose and a carrier are taken and fully mixed to be ground and prepared into dry powder. The raw materials of the invention has the advantages of stable source, simple preparation, wide material source and low cost; due to the stress principle of fish body, the anti-stress agent not only supplements Chinese herbal medicines, but also complements western medicine of glutamine dipeptide; the combination of Chinese herbal medicines and western medicine regulates the stress of fish body, and appropriately supplements the loss of Na<>, K<> caused by stress to control the stress of fish body. When in use, the anti-stress agent can be added into feed and directly splashed; the immunity and inhibiting ability of fish body can be improved, the capacity of resisting high temperature and high density as well as infection resistance for resisting hydrophile aeromonas can be improved, and the growth of the fish body can be accelerated.

An anti stress immunity enhancing agent for pig, the weight ratio range of its component and dry matter is: citric acid 13 to 21 percent; oligomerization Fructose 15 to 25 percent; vitamin C 2 to 3percent; vitamin E 0.5 to 1 percent, vitamin B1 0.4 to 1.0 percent; vitamin B12 0.1to 0.6 percent; garlicin 1 to 4 percent; astragalus polyase 1 to 6 percent; bacitracin zinc 3 to 5 percent; the rest is carrier. The said anti stress immunity enhancing agent has reasonable compound, stable material resource, lower cost, simple producing technology, its merit is: increasing feed intake for pig, promoting growth; enhancing immunity of pig, preventing and curing diarrhea, tail-biting, anorexia etc stress symptom during the weaning, transforming, and transfer to group.

The invention relates to a method for preparing a mixed-type nucleotide feed additive from yeast cells and applications of the feed additive, which belong to the technical field of the preparation of nucleotide feed additives from yeast cells. The method comprises the steps: using yeast cells as raw materials and combining a homogenization method and a salt method to break yeast cell walls ; separating the yeast cell walls, protein and other insoluble substances by centrifugation and fractional isoelectric crystallization; specially collecting RNA precipitates at special isoelectric points to obtain wet and crude nucleic acid with the purity of 70 percent; dissolving the wet and crude nucleic acid in water, using high-activity phosphodiesterase from malt roots to carry out a high-efficiency directional enzymatic reaction; directly spraying, drying and crushing the solution after the enzymatic reaction to obtain the mixed-type nucleotide feed additive product comprising the protein content lower than 10 percent and four monosomic nucleotides (AMP, GMP, CMP and UMP) larger than 60 percent. After the feed additive is applied to animal feed, the intestinal absorption function of animals can be notably improved, the growth of the animals is stimulated, and the immune function, the antiviral capability and the anti-stress capability of the animals are improved.

A cable connector assembly (100) includes an electrical connector (1) including an insulative housing (10), a number of conductive contacts (12) received in the insulative housing and a conductive shield (11) enclosing the insulative housing, a cable (5) including a number of lines (520, 522), a printed circuit board (4) electrically connecting the conductive contacts of the electrical connector with the lines of the cable, and a shielding member (2) electrically connecting with the electrical connector and secured with the printed circuit board and the cable. The shielding member forms a number of deflecting members (212) for securing to a panel (3) and a number of anti-stress members for preventing the deflecting members from excessive deformation.

The invention belongs to the field of feeds, relates to an aquiculture feed and particularly relates to a penaeus vannamei compound feed special for high salinity (over 3%) cultivation and a preparation method of the compound feed. The penaeus vannamei compound feed contains 3-6 parts of euphausiid meal, 20-35 parts of fish meal, 2-4 parts of fly maggot meal, 3-7 parts of chicken meal, 1-5 parts of silkworm chrysalis meal, 2-6 parts of squid liver paste, 2-5 parts of shrimp shell meal, 1-3 parts of algae powder, 3-8 parts of fermented soybean meal, 3-13 parts of soybean meal, 3-8 parts of peanut meal, 2-7 parts of corn gluten meal, 10-20 parts of wheat flour, 4-10 parts of monosaccharide and / or oligosaccharide, 2-6 parts of sleeve fish liver meal, 2-4 parts of fish oil, 1-2 parts of soybean oil, 1-3 parts of soybean phospholipid powder, 0.1-0.4 part of choline chloride and 1-3 parts of monocalcium phosphate. The penaeus vannamei compound feed is capable of meeting the growth requirement of penaeus vannamei for nutrition under high salinity (over 3%), good in stability in water, strong in anti-stress capability, high in survival rate and growth speed and low in feed coefficient.

The invention provides a Cu-Ni-Sn-P alloy sheet satisfying the resistance property of stress relaxation in the direction perpendicular to the rolling direction and excellent in the other necessary properties as terminals and connectors. The invention relates to analloy sheet having a specific composition, which is made to contain specific atomic clusters containing at least any of an Ni atom or a P atom, as detected with a three-dimensional atom probe field ion microscope, in a specific density, by increasing the reduction ratio in the final cold rolling and by intentionally shortening the time for the rolling and the time to be taken before the final annealing at low temperature, and of which the necessary properties as a terminal or connector 3 are improved in that the resistance property of stress relaxation thereof in the direction perpendicular to the rolling direction is enhanced and the difference (anisotropy) in the resistance property of stress relaxation thereof between the parallel direction and the perpendicular direction to the rolling direction is reduced.

The invention discloses an acidating agent for newborn piglet feed and preparation method thereof, relating to the feed additive field. The acidating agent is composed of the following raw materials by parts by weight: 40-55 parts of L-lactic acid, 20-25 parts of boletic acid, 2-4 parts of citric acid and 21-38 parts of auxiliary material, wherein the auxiliary material comprises the following components: 2-3% of dextrin, 7-8% of carboxymethyl cellulose cellulose sodium, the balance white carbon black; the raw materials added with water, mixing and spray granulation are carried out, so as to produce liquidity uniform granules. Pure organic acid composition is adopted, not only pH value of gastrointestinal tract can be reduced, but also sterilization anticorrosion can be realized, so as to regulate and control flora balance of gastrointestinal tract, thus being beneficial to breeding and growth of beneficial fungus such as lactic acid bacillus, inhibiting quantity of harmful fungus such as colibacillus and the like, improving animal anti-stress effect and improving animal immunity; and the acidating agent can directly participate in internal supersession, release energy, promote absorption of mineral substance, vitamin and nutritive material and improve animal production performance.

The invention discloses a high-strength high-toughness corrosion-resistant Al-Zn-Mg-(Cu) alloy. Appropriate Cr is also added when Zr is added in the Al-Zn-Mg-(Cu) alloy; or when the Zr is added, the Cr and rare earth element Er or Yb are added. After composite addition of the elements, the invention can improve recrystallization resistance of the Al-Zn-Mg-(Cu) alloy, improve the strength, the fracture toughness and the anti-stress-corrosion performance of the alloy at the same time; micro-alloys such as Zr, Cr and so on, and the rare earth metal Er or Yb have relatively low cost and are more suitable for industrialization production.

The present invention provides a proprietary compositions and systems to modulate genetic and metabolomic contributing factors affecting disease diagnosis, stratification, and prognosis, as well as the metabolism, efficacy and / or toxicity associated with specific vitamins, minerals, herbal supplements, homeopathic ingredients, and other ingredients for the purposes of customizing a subject's nutritional supplement formulation to optimize specific health outcomes. Specific to this invention the utilization of certain known polymorphic genes associated with Substance Use Disorder (SUD) are analyzed to target certain genetic anomalies that lead to a high risk and predisposition to SUD. The genotypic patterns are then utilized to provide certain nutritional customized solutions especially related to the attenuation of aberrant abuse of physician prescribed narcotic pain medication across all pain conditions. A priority GENOPROFILE is measured and directs the customization of a subsequent nutraceutical to act as a therapeutic modality. Specifically the treatment includes slow attenuation of the pain medication by incorporating orals (shakes, liquid beverages, pills, tablets, troche, ointments etc.), Intramuscular, Intravenous, intra-rectal and any form necessary to deliver a sufficient amount of an anti-craving and anti-stress nutraceutical. Moreover, the invention includes examples of novel analgesic ointments coupling Synaptamine and such analgesic and other anesthetic compounds including but not limited to Gabapentin, Ketamine, Baclofen, Ketoprofen, Amitriptyline, Lidocaine, Cyclobenzapine, Diclofenac, Menthol, Camphor and Capsaicin. The GENOPROFILE will be used to determine pain sensitivity Intolerance.

The invention discloses an efficient environmental-friendly black carp extrusion compound feed and a production method thereof. The method is characterized by comprising the following steps: mixing large amounts of other raw materials such as fish meal, extruded-soybean, soybean meal, rapeseed meal, cottonseed meal, wheat and rice bran and then coarsely crushing a mixture; adding spray-dried animal blood cells, larvae powder, monocalcium phosphate, choline chloride and salt for evenly mixing, carrying out superfine crushing; adding vitamin premis, mineral premix, rheum emodin, L-carnitine and allicin for evenly mixing; and carrying out steam tempering, extrusion, granulation, drying, spraying, cooling and the like on the mixed materials to obtain the product. The black carp extrusion compound feed is simple to prepare and has comprehensive and balanced nutrition, the digestibility of the black carp on feed nutrient substances can be improved, the feed coefficient is reduced, and the nitrogen and phosphorus emission is lowered. The feed has good palatability, excellent stability in water, and less feed wastes and water pollution. The feed can increase the immunity, antioxidation and anti-stress capabilities of the black carp, and promotes the growth of the black carp.

The invention discloses a microbiological feed additive for replacing antibiotics, mainly comprising bacillus subtilis, saccharomyces cerevisiae, aspergillus niger, aspergillus oryzae and the like. The preparation method of the microbiological feed additive comprises the following steps: parent species of all strains are prepared by liquid state fermentation, production species are prepared by carrying out solid state fermentation on the parent species, the strain is obtained by carrying out further solid state fermentation on the production species, and the strains are mixed according to a certain proportion to obtain the microbiological feed additive. The microbiological feed additive can improve the nonspecific immunity of animals, enhance the anti-stress capability of an organism, activate the growth potential of the animals, improve the production performance comprehensively, solve the problems of low quality of products, loss of flavor, diarrhea of piglets, constipation of sows,shapeless feces of chickens and ducks, more anti-nutritional factors of feedstuff materials and low digestion and utilization in a package manner, and provide a low-cost, simple and practical scheme for replacing the antibiotics, an enzyme preparation, arsenical preparations and probiotics.

The invention relates to melatonin solution capable of improving the anti-stress capability of a plant. The melatonin solution contains a solvent, wherein the concentration of melatonin in the solvent is 75-100mmol / L; the anti-stress capability is salt-resistant, cold-resistant and iron deficiency-resistant capability; the working concentration of the melatonin solution is 75-100micromol / L after the melatonin solution is diluted by distilled water; preparation steps are as follows: adding melatonin in the solvent suitable for being used in agricultural production, stirring and dissolving to obtain a finished melatonin solution product. According to the melatonin solution disclosed by the invention, simple and practicable effects are achieved, the operation is simple, the stability is good, and salt-resistant, cold-resistant and iron deficiency-resistant capability of the plant can be improved.

The invention discloses a special compound feed for crabs. The compound feed consists of soybean meal, rapeseed meal, peanut meal, corn protein powder, spray-dried animal blood cells, fish meal, shrimp meal, four, fish dissolving-pulp protein powder, yeast extract, fish oil, soybean lecithin oil, bentonite, monocalcium phosphate, a mildew preventive, mannan oligosaccharide, glycine betaine, a hulling element, methionine, choline, perilla seed extract, a vitamin premix and a mineral premix. The raw materials of the compound feed are stable in source, high in utilization ratio, balanced in nutrient content and relatively low in cost. The preferred fish dissolving-pulp protein powder enhances the feed attraction of the feed. An advanced puffing process is adopted so as to further improve the utilization ratio and water resistance of the feed and reduce waste and water pollution. Meanwhile, an immune nutrition additive is adopted so as to significantly enhance the immune function and anti-stress capacity of the crabs and significantly increase the survival rate. The compound feed is much greener and more environmentally friendly, and efficiency increase is particularly significant in a high-density river crab breeding mode.

The invention relates to a new pharmacotherapeutical strategy, to an anti-stress, anti-impairment and anti-aging drug and to a process for its manufacturing. The drug has an etio-pathogenic and homeostatic action, was preclinically tested and clinically checked up in geriatric, neurologic, psychiatric and stress-dependent pathology. The drug achieves a synergistic biological, neurometabolic and cell-trophic composition, being elaborated by the association of the following active principles: a) against oxidative and catabolic stress; methionine with aminoethanol phenoxyacetates and / or aminoethyl phenoxyacetamides; b) against anabolic stress; hydroxopyrimidine carboxylates and / or oxopyrrolidine acetamides with potassium, zinc and lithium; c) vasodilative and normolipidemic; nicotinic, alcohol and / or acid, or its derivatives, with magnesium and iodine; d) energo-active and e) anti-toxic; aspartate; fructose; vitamin B1; vitamin B6; monoacid phosphate and sulfate. The process for manufacturing the drug stipulates; a) pharmaceutical preparation in two complementary types of capsules or coated tablets, gastrosoluble and enterosoluble, the last being enteric coated; b) prolonged-release of vasodilator from the enterosoluble unit.

The invention relates to a megalobrama amblycephala anti-stress feed and a production method thereof. The preparation method is characterized by comprising the following steps of: crushing fish meal, bean pulp, silkworm pupa, rapeseed meal, rapeseed, cottonseed meal, all-purpose flour, sub-powder, washed rice bran, and potassium sorbate mildew preventive; stirring and uniformly mixing the crushed product and fish oil, lecithin, 50 percent choline chloride, rhubarb anthraquinone extract, premix for fish, attapulgite, 35 percent phosphate vitamin C, 50 percent vitamin E and monocalcium phosphate; after stirring and uniformly mixing, grinding the mixture into mixed materials by using an ultra-micro grinder; and preparing the materials into a pellet feed by using the conventional method of the pellet feed. The pellet feed has total and rich nutrition, and can improve the immunity and oxidation resistance of the megalobrama amblycephala, improve the stress, enhance the resistance to disease, improve the feed palatability, and accelerate the growth.

A process for efficiently, easily and stably producing tripeptides Val-Pro-Pro and Ile-Pro-Pro, which are useful as hypotensive drugs, anti-stress drugs, etc., by an enzymatic method. This process involves the step of cleaving a milk casein-containing material with a proteinase to form an intermediate peptide selected from the group consisting of a peptide containing the sequence Val-Pro-Pro but having no Pro other than this sequence, a peptide containing the sequence Ile-Pro-Pro but having no Pro other than this sequence, and a mixture of these peptides, and then cleaving the intermediate peptide with a peptidase to thereby give at least one of the tripeptides Val-Pro-Pro and Ile-Pro-Pro.

The invention relates to a feed additive premix for low-salinity cultured marine fishes. The feed additive premix for the low-salinity cultured marine fishes consists of multi-vitamins and composite trace elements, and 20 to 30kg of feed additive premix is added into each ton of marine fish feed, wherein the multi-vitamins are 5 to 10kg and the composite trace elements are 15 to 25kg. Long-term tests of the low-salinity cultured marine fishes in the Pearl River Delta, such as trachinotus ovatus, Japanese sea bass, sciaenops ocellatus, sparus latus, sparus macrocephalus, latescalcarfer and the like, prove that the feed additive premix for the low-salinity cultured marine fishes has comprehensive nutrition and can meet the requirement of various marine fishes on total nutrition in a low-salinity culture environment; the feed additive premix is safe and high-efficiency, does not have any toxic or side effect, makes cultured objects grow rapidly and has high feed conversion rate and good culture benefit if taken for a long time; meanwhile, the additive can obviously enhance the immunologic function and anti-stress capability of the cultured objects, and the cultured marine fishes have high vigor, bright body color and high survival rate.