The invention discloses a pharmaceutical composition for regulating menstruation and relieving pain, and a preparation method, a preparation and an application thereof. The pharmaceutical compositionfor regulating menstruation and relieving pain comprises 10 to 30 parts of
bupleurum root in parts by weight of raw materials, 10 to 30 part of angelica, 10-30 part of radix paeoniae alba, 10-30 partsof rhizoma ligustici chuanxiong, 10-30 part of rhizoma cyperi preparata, 10-30 parts of radix
codonopsis pilosulae, 10-30 parts of
atractylodes macrocephala, 10-30 parts of tuckahoe, 10-30 part of peach kernel, 10-30 parts of
salvia miltiorrhiza, 10-30 parts of rhizoma
corydalis prepared with vinegar, 10-30 parts of
pollen Typhae, 10-30 parts of mint, 10-30 parts of liquorice and 10-30 parts of ginger. The preparation comprises decoction, ointment, tablet,
powder,
capsule, granule and
pill prepared by adding pharmaceutically acceptable
adjuvant into the pharmaceutical composition for regulating menstruation and relieving pain. The pharmaceutical composition used for regulating menstruation and relieving pain is used for preparing menstruation regulating and relieving pain medicines. As the
medicine of the invention are combined and synergistically effect, menstruation regulating and pain relieving effects are achieve.