The invention discloses externally applied plaster for treating rheumatism, rheumatoid arthritis and neck-shoulder and lumbocrural pain. The plaster is prepared from nux vomica, common monkshood mother root, kusnezoff monkshood root, eupolyphaga, cinnamon, white mustard seed, long pepper, notoginseng root, frankincense, myrrh, dragon's blood, asarum, whole worm, centipede, garter snake, long-noded pit viper, geosaurus, cloves, clematis root, dried ginger, angelica sinensis, ligusticum wallichii, safflower, garden balsam stem, wooly datchmanspipe herb, ovientvine, kadsura pepper stem, caulis spatholobi, incised notopterygium rhizome, heracleum, gentiana macrophylla, divaricate saposhnikovia root, rhizoma drynariae, scirpus fluviatilis, zedoary, cassia twig, rhizoma corydalis, borneol, camphor, sesame oil and minium; the plaster can dispel wind and clear damp, dispel cold and activate collaterals, activate blood and dissolving stasis, diminish swelling and dissipate binds, and has good effects on rheumatism, rheumatoid arthritis, protrusion of lumbar vertebral disc, knee arthritis, and osteoproliferation and does not have any toxic or side effects.