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6248 results about "Water environment" patented technology

Special biological fish-fertilizer for aquaculture and preparation method thereof

The invention discloses a special biological fish fertilizer and a preparation method for the fertilizer used in aquiculture; wherein, the biological fish fertilizer mainly comprises raw materials as follows: microbiological preparation, inorganic fertilizers, fermentation organics, micro-mineral amino acid chelate, mineral composites, and water quality improver. The preparation method for the special biological fish fertilizer in aquiculture comprises steps as follows: microbiological preparation is produced; fermentation organics is then produced, and the micro-mineral amino acid chelate is produced, eventually the finished products are made. The special biological fish fertilizer has the advantages of limiting the growth and reproduction of the harmful algae, promoting the large-scale growth and reproduction of the suitable food for fish, effectively improving the water quality and purifying the water environment, strengthening the fish immunity, reducing the diseases, reducing cost due to the small use level, convenient use, mild odor, no pollution to the water, and environment protection. By combining the modern bioengineering technique, low-temperature drying technique, spray-drying technique, and super-fine crushing techniques, the preparation method has the advantages of stable quality for the fish fertilizers and lower overall cost.
Owner:WUHAN KEYANG BIOTECH

Stereo in-situ ecological urban water system repairing process

The stereo in-situ ecological urban water system repairing process tackles polluted water via the quantitative analysis on the water. The technological scheme includes physical simulation and mathematic model analysis, microbe inoculation and culture, constituting refluxing ecological filter bed, purification with biocarrier, artificial aeration, purifying upper water, pre-treatment in the blow down port, establishing water ecological system balance, perfecting water environment data, etc. The present invention realizes the comprehensive tackling of urban water system.
Owner:上海中渠生态环保科技有限公司

Metal heavy absorbent and preparation method and use thereof

The invention discloses a heavy metal absorbent and a preparation method and use thereof. The heavy metal absorbent is prepared by using an inorganic mineral modified by a surfactant as a carrier and loading organic complexing agent on the carrier, wherein the inorganic mineral is bentonite, kaolin, kieselguhr, zeolite, aluminum oxide or iron oxide; the surfactant is cationic surfactant or nonionic surfactant; and the organic complexing agent is a compound containing a sulfydryl and an amino. The heavy metal absorbent has the advantages of stable performance, environment friendliness, high absorption capacity, high selectivity, convenient post-recovery treatment and the like. The absorption capacities of cadmium, mercury lead and other heavy metals all exceed 100mg / g, and the heavy metal absorbent can achieve good treatment effect in treatment of water and soil environments polluted by heavy metals.
Owner:上海伊克诺环境科技有限公司

System and method for wireless monitoring of aquaculture water quality

The invention relates to a wireless acquisition device of culture water quality, which comprises a sensor group, a microprocessor and a wireless communication module. Based on the wireless acquisition device, the invention also discloses a system for wirelessly monitoring the culture water quality, which comprises a data storage module, a power supply module and a buoy. The device and the system adopt a solar energy supply; the system has an online state and a dormant state; software and hardware are designed by adopting a low power consumption power-saving mode, and can acquire and store a plurality of water quality parameters such as the pH value, the electrical conductivity (EC), the water level, the dissolved oxygen (DO) and the water temperature of a culture water environment; the acquired data can be sent to a data monitoring center by GPRS; and the DO value in water can be predicted, and water quality DO early warning information is sent to an intensification aquaculture manager through mobile phone short messages.
Owner:CHINA AGRI UNIV

Water environment vertical distribution comprehensive on-line monitoring buoy and monitoring system

InactiveCN105842412ARealize measurementOvercome the disadvantages of being restricted by geographical locationWaterborne vesselsTesting waterReal time analysisEngineering
The invention relates to a vertical distribution comprehensive on-line monitoring buoy and a monitoring system and belongs to the technical field of environment pollution monitoring. The buoy includes a buoy body, an electronic device sealing cabin, a Beidou satellite navigation positioning module, a storage battery pack, a data collector and a 4G router, and a sensor which is arranged on periphery of the buoy body, and a power supply apparatus arranged on the upper part of the buoy body. The invention provides the self-moving monitoring buoy which can perform an environment monitoring operation task continuously for long time in a preset waste area range, wherein the buoy can measure water environment parameters and environmental meteorological parameters in different depth. The Beidou satellite navigation positioning module and 4G communication network are switched to achieve positioning and communication of the buoy. The buoy and the system achieve real-time monitoring, real-time analysis and alarm prediction of monitoring regional environment parameters.
Owner:CHONGQING INST OF GREEN & INTELLIGENT TECH CHINESE ACADEMY OF SCI

Permeable recycled aggregate and ceramsite concrete doped with industrial and agricultural solid waste and preparation

The invention discloses permeable recycled aggregate and ceramsite concrete doped with industrial and agricultural solid waste and preparation. The permeable recycled aggregate and ceramsite concrete doped with industrial and agricultural solid waste is characterized in that recycled coarse aggregates and ceramsites are taken as coarse aggregates of concrete, an appropriate amount of pretreated industrial and agricultural solid waste such as industrial waste, agricultural waste, household garbage and the like is taken as an admixture, a cementing agent is prepared from cement, water, a superplasticizer and a reinforcement material, and the materials are mixed with a preset stirring process and preparation method, so that ecological concrete with good mechanical property, permeable property and durability is produced. According to the concrete, the waste utilization rate is up to about 80%, the concrete is environment-friendly, locally available materials can be used, the economic benefit is remarkable, ceramist pore is smaller, and sewage can be continuously and stably treated, so that the concrete is commonly used in water environment comprehensive improvement engineering; and besides, the concrete has light weight, high strength and good water permeability and can be also used in permeable pavement engineering such as a sidewalk, a parking lot and the like as well as plant engineering such as ecological riverway slope protection, roof landscape planting and the like.
Owner:YANGZHOU UNIV

Multicomponent composite flocculating setting agent and use in arsenic contamination water treatment

The invention belongs to the technical field of river water body pollution control and in particular relates to a multiple-element compound flocculating settling agent and the application of the multiple-element compounded flocculating settling agent in arsenic pollution water body treatment. The multiple-element compounded flocculating settling agent is prepared by compounding malysite, aluminium salt, hypermanganate, polyacrylamide and aqueous solution. The multiple-element compounded flocculating settling agent can be applied in the arsenic pollution water body treatment to remove arsenic in the arsenic pollutant water body. The concentration of the arsenic in the treated water can meet or is superior to the specified requirement of three types of water on the arsenic concentration in the national earth surface water environment quality standard (less than 0.05 mg / L). The invention also can be used for removing heavy metals such as copper, chromium, cadmium, lead and the like in water by sedimentation. The multiple-element compounded flocculating settling agent can be used together with a multiple-element compounded metal oxide arsenic removal setting agent in static or flowing arsenic pollution water body treatment for removing the arsenic in the water body polluted by arsenic.
Owner:RES CENT FOR ECO ENVIRONMENTAL SCI THE CHINESE ACAD OF SCI

Water environment monitoring and quality-control data analysis method

The invention belongs to the field of data analysis, and in particular relates to a water environment monitoring and quality-control data analysis method. The method is characterized by comprising the following steps of: a, acquiring water environment quality-control data to be verified; b, establishing a support vector machine water environment quality-control data forecasting module; c, comparing the quality-control data output with quality-control data in historical data which is identical in analysis method and instrument type, to obtain a deviation; and d, determining whether the verification of the data passes or not by the following specific steps of: judging that the data is rational and the verification passes if the deviation is not high, and adding into a historical dataset; or if the deviation is excessively high, classifying the data as suspect data. According to analysis research method disclosed by the invention, in analysis of the water environment monitoring and quality-control data, the problem on processing, verification and analysis of various rapid increasing and nonlinear multivariable monitoring and quality-control data is solved, and the demand of scientific management is met.
Owner:JIANGSU ENVIRONMENTAL MONITORING CENT

Water-quality simulation method based on control-unit water-environment-quality target management

ActiveCN108287950ASolve the problem of land and water couplingData processing applicationsGeneral water supply conservationRiver networkStreamflow
The invention provides a water-quality simulation method based on control-unit water-environment-quality target management. The water-quality simulation method includes the steps that a database is built; a land-field control unit and a river-way subunit are divided; the flow, the area of the water surface and the volume of a water body of calculation unit grids are simulated through a hydraulicsmodel; the generation quantity of non-point-source pollutants in pollution sources is calculated through an output coefficient model, and the in-river sewage amount and the pollution load concentration of pollutants of a pollutant discharging opening are calculated; the water quality of the calculation unit grids is simulated through a one-dimensional water-quality model. In the water-quality simulation method, an emergent risk accident pollutant-discharging water-quality model is also used, and is used for simulating transmission of accident pollutants in a river network and the changing condition of the water quality of a downstream drainage basin after emergent-water-environment-risk-accident pollutant discharging.
Owner:CHINESE ACAD OF ENVIRONMENTAL PLANNING

River crab integrated culture method in ponds

The invention discloses a river crab integrated culture method in ponds. The river crab integrated culture method in the ponds comprises the following steps of preparing the ponds; equipping the ponds with escape-proof facilities, water inlet and drainage facilities and bottom aeration facilities; breeding snails, river crabs, freshwater shrimps, dark sleepers and Aristichthysnobilis; planting aquatic plants; feeding feedstuff; managing water quality and sloughing. According to the river crab integrated culture method in the ponds, the ecological layout is adjusted, the self-purifying capacity of the ponds is improved, the pressure exerted on creatures by eutrophication of a water environment and the ponds can be released, the ecological balance and the stabilization of the water quality can be kept, and accordingly the disease incidence are reduced and the foundation for achieving high and stable yields is laid; meanwhile, existing culture facilities are fully taken advantages of, the comprehensive productivity of the ponds is improved, and accordingly the overall economic benefits are improved. The river crab integrated culture method in the ponds is beneficial to utilizing solar energy and the feedstuff to the utmost, preventing diseases and improving the capacity of resisting natural and market risks. Through the embodiment of the river crab integrated culture method in the ponds, the disease incidence of the crabs cultured in the ponds can be reduced, and the culture loss and culture risks can be reduced. The predicted comprehensive benefits of the culture can be improved, and meanwhile the pollution of the ecological environment of a water area caused by the culture can be reduced.
Owner:叶建生

Aqueous environmental protection ultration expansion type steel structure fireproof paint and its preparation method

The present invention provides a water environment-protecting superthin expanded type steel structure fire-retardant coating. Said fire-retardant coating uses water as dispersion medium, uses flake expandable graphite as expansion reinforcing material, uses one or several kinds of emulsions of acrylic emulsion and others as film-forming material, and its expansion system adopts the ingredients of polyammonium phosphate, pentaerythritol and tripolycyanamide. Said invention also provides its preparation method and concrete steps.
Owner:北京首纳东方科技有限公司

Method of aquaculture

A method of aquaculture is applicable to a novel culture arrangement for diversified farming of generally deep sea fin fishes, shrimps, and shellfishes. A pre-manufactured enclosed cultivation tank is provided and air compressor facility is included for pressurization and oxygenation so as to make the interior of the cultivation tank a pressurized water environment of predetermined high pressure. A low pressure siphon tube is included for sucking and removing excrements from the cultivation tank and to realize water replacement in a natural manner thereby providing a deep sea mimicked clean cultivation environment. The drained water is subjected to multiple steps of filtration and purification for separating the excrements from the water and for purifying water to allow cyclic use of the water. An arrangement of multiple cultivation tanks allows for diversified and multi-species cultivation of fishery products and deep sea fishes.
Owner:NIEN TE CHIH

Direct power-spectral method-based all-weather long drainage basin water quality monitoring and early-warning system

The invention relates to a direct power-spectral method-based all-weather long drainage basin water quality monitoring and early-warning system, belonging to the technical field of water quality monitoring. The system comprises a plurality of water quality monitoring devices, a cloud data processing platform and a remote monitoring platform; the water quality monitoring devices are placed at a shoreside of a water body, a water surface buoy or other water surface platforms according to needs, used for extracting water quality data of the long drainage basin, use a direct power-spectral method to acquire an absorption spectrum of a monitored water body and sends the monitored data and water quality information to the cloud data processing platform in a wireless transmission manner; the cloud data processing platform summarizes and analyzes the received data and stores into a database; the remote monitoring platform inquires and displays the data stored in the database and realizes the real-time monitoring and early-warning for an all-weather long drainage basin water quality environment. The system can realize the online measuring, real-time monitoring, emergent early-warning, drainage basin analyzing and water environment monitoring of all weathers of the water body in the drainage basin, thus reducing the loss caused by pollution to the water body and ensuring drinking water safety.
Owner:CHONGQING UNIV

Water environment pre-warning and comprehensive management platform

The invention discloses a water environment pre-warning and comprehensive management platform, and belongs to the technical field of water environment monitoring. The platform mainly comprises an information management module, a water environment analysis and evaluation module, a water environment pre-warning and forecasting module, a water environment comprehensive management module, a GIS systemmodule and a data monitoring module. According to the platform, information of each partition basin and information of surrounding pollution sources of each monitoring point are established, so thatpertinence for the key monitoring and precaution for the key areas and key elements with potential safety hazards is strengthened; and analysis, assessment and trend analysis are carried out on waterquality of the monitoring points, and a water quality pre-warning and forecasting model is constructed, so that monitors are helped to timely recognize water environment pollution areas and pollutionlevels, and deciders are helped to carry out correct judgement, timely processing and effective measure implementation when accidents occur, thereby strengthening the comprehensive management for water environment of offshore areas.
Owner:SOUTH CHINA INST OF ENVIRONMENTAL SCI MEP +1

Prepn process of resin-based dearsenifying adsorbent

The resin-based dearsenifying adsorbent is prepared with macroporous and gel type strong alkaline anionic exchange resin as basic material and water solution of FeCl3, HCl, NaCl in different compounding proportions as reagent, and through reaction. The strong alkaline anionic exchange resin has Fe(III) carrying amount of 2-9 wt%. Compared with strong alkaline anionic exchange resin without Fe(III) carried, the strong alkaline anionic exchange resin with Fe(III) has even higher adsorption selectivity and adsorption capacity on high toxicity As(III) and As(V) in water and excellent kinetic performance. The resin-based dearsenifying adsorbent of the present invention has greatly raised, normally 200 times raised, adsorption selectivity on micro as in water solution, and raised, normally 40-300 % raised, adsorption capacity, and is favorable to improving water environment quality.
Owner:JIANGSU NJU ENVIRONMENTAL TECH

Water body experiment apparatus and method

The invention relates to a water body experiment apparatus and a water body experiment method. The apparatus comprises a sediment release unit, a culture unit, a control unit, a water body controlling system, and a water quality monitoring system. The sediment release unit, the culture unit, and the control unit are sequentially arranged adjacently. Each two adjacent units are connected with a baffle, such that an experiment box body with the three units communicating with each other is formed. The water body controlling system is used for regulating physical and chemical indicators of water body in the experiment apparatus. The water quality monitoring system is used for detecting the physical and chemical indicator values of water body, sediment, plankton and / or submerged aquatic plants in the experiment apparatus. According to the invention, sediment sampling, sediment pollutant releasing, and algae and submerged plant growing are effectively combined. With the apparatus, sediment release effect of different water environments can be simulated, and influences of different ecological projects (environmental-protection dredging projects and submerged aquatic plant restoration projects) upon water body eutrophication and water body pollution can be quantitatively studied.
Owner:CHINESE RES ACAD OF ENVIRONMENTAL SCI

Ecological restoration and purification method for landscape water environment

The invention discloses an ecological restoration and purification method for landscape water environment which is characterized by comprising the following steps of (1) performing bottom mud sterilization and activation treatment; (2) splashing a microbial flora compound preparation; (3) reconstructing a submerged communities; (4) repairing an aquatic ecosystem food chain; and (5) performing aquatic ecosystem conservation management. According to the ecological restoration and purification method for the landscape water environment, a biological integrated control technology is applied, and the water purification effect is achieved by use of submerged plants; furthermore, decomposers, namely microorganisms in an ecosystem are fully utilized, and multiple types of aquatic animals are put in the aquatic ecosystem, so that the ecosystem food chain is perfected, various aquatic species promote and restrict one another, the whole riverway, lake, pond and wetland system is kept in dynamic balance for a long time, the original self-purification capability of the aquatic ecosystem is restored, and a long-term stable effect is achieved.
Owner:佛山五色时空生态环境科技有限公司

Feed for litopenaeus vannamei

The invention discloses a feed for litopenaeus vannamei, which comprises the following nutrition compositions by mass percent: 25-35% of proteins, 4-9% of fat, 7-12% of ash contents, 40-55% of carbohydrates and 3-11% of water. The feed can meet the nutrient requirement of litopenaeus vannamei for best growth, and effectively solves the traditional problems of high protein level of a compound feedand severe environmental pollution in the process of culturing litopenaeus vannamei; the industrial profit is increased, and the pollution and the damage to a water environment in the process of culturing are reduced; and the sustainable development of litopenaeus vannamei culturing industry is realized.
Owner:SUN YAT SEN UNIV

CPG feedback control method of biomimetic robot fish movement

ActiveCN101916071AFlexible Autonomous Swimming ControlImprove applicabilityAdaptive controlComputer moduleEngineering
The invention relates to a CPG (Certified Program Generator) feedback control method of biomimetic robot fish movement, comprising the following steps of: providing a CPG feedback control model for receiving feedback signals by using different parts of a high-level control module, a CPG, a motor neuron, and the like; receiving biomimetic robot fish body state information and water environment information by the high-level control module; transmitting a corresponding command by treating the information and making a decision; and selecting a corresponding movement moulding plate to determine a suitable CPG configuration, wherein the suitable CPG configuration is used for controlling the parts of the biomimetic robot fish body to carry out rhythmic movement and non-rhythmic movement. The invention provides a reference for the feedback control theoretical design of the biomimetic robot fish movement and can realize mobile, flexible and independent autokinetic movement.
Owner:INST OF AUTOMATION CHINESE ACAD OF SCI

Stratum grouting simulation system

InactiveCN105137048APerfect security warningImprove securityMaterial testing goodsSoil scienceData acquisition
The invention relates to a stratum grouting simulation system, comprising a model load box (2) for containing rock soil, a loading subsystem (3) for loading the rock soil from the top end so as to restore an underground stress field environment, an underground water simulation subsystem (4) for controllably injecting water to the rock soil and discharging the water from the rock soil so as to simulate still water and dynamic water environments, a grouting subsystem (5) for grouting into the rock soil, a data acquisition subsystem (6) for measuring stress, strain and displacement data of the rock soil, and an alarm subsystem (7) for measuring deformation of the model load box (2), pressurizing pressure and grouting pressure and with an alarm function, wherein the side wall of the model load box (2) is provided with a detachable wall plate. The stratum grouting simulation system is lower in cost, and capable of simulating an excavation process, a deeper underground environment, dynamic water and vadose environments.
Owner:BEIJING UNIV OF CIVIL ENG & ARCHITECTURE

System for restoring bio-ecological environment of micro-polluted riverway

The invention relates to the technical field of water environment ecological restoration, in particular to a system for restoring bio-ecological environment of a micro-polluted riverway, wherein a biological contact oxidation module adopts elastic three-dimensional packing or combined packing, the riverway coastal area is provided with emergent aquatic plant floating floors or floating plant floating floors, the upstream and the downstream of the riverway are provided with floating plant purification zones, and the water surface coverage of the floating floors is between 15 and 20 percent; both coasts of the riverway are plated with emergent aquatic plants and the water surface is planted with floating plants, and water areas with more than two times of transparency are plated with submerged vegetations; and sloping fields on both sides of the riverway are planted with un-germinated poplar or willow branches through cottage; and simultaneously, the poplar or willow branches are embedded into sloping banks shallowly and horizontally according to contours in a mode of being bundled up into a bunch of fascines at different positions of the sloping fields. Compared with the prior art, for the ecological restoration and construction, the system achieves self-purification, self-regulation and self-sustaining of pollutants within certain concentration range, and is an effective path for improving water quality under the condition that basin-wide pollutant cutoff cannot be performed at present.
Owner:EAST CHINA NORMAL UNIV

Combined ecological floating bed restoration system

The invention relates to the technical field of ecological restoration of water environment, and especially relates to a biological and ecological restoration system of eutrophic rivers and lakes. Ecological floating beds are laid along a bank, the water surface coverage rate of the floating beds is 15-20%, and each of the floating beds consists of a floating plate, planting baskets, a planting basket filler, floating bed plants, a nylon net, immobilized microorganism particles, a biological filler and artificial waterweeds. The planting baskets are placed in the planting basket holes of the floating plate, the planting basket filler is arranged in the planting baskets, the floating bed plants are planted in the planting basket filler, the nylon net suspends below the floating plate, the immobilized microorganism particles suspend between plant roots, the biological filler suspends below the nylon net, the artificial waterweeds are planted at the water bottom, and submerged plants are properly planted in a water area with two times in the transparency. The system has the advantages of simple and economic carrier, high strength, good durability, reliable planting, natural water ecological landscape, and engineering water quality improvement; and compared with systems in the prior art, the system focuses on the ecological restoration and construction of river and lake water, realizes the self purification, self regulation and self maintenance of pollutants in a certain concentration range, and is an effective way to improve the water quality without all-basin pollutant interception at the present stage.
Owner:昆山瀚潮环保科技有限公司

Regional water environment heavy metal monitoring system and operating method

The invention discloses a regional water environment heavy metal monitoring system and an operating method. The regional water environment heavy metal monitoring system comprises a monitoring management system and a plurality of monitoring terminals, wherein the monitoring terminals are connected with the monitoring management system through general packet radio service (GPRS); a central processing unit of the monitoring management system is connected with a data transmitting and receiving module, a data analysis processing module, a database management module and a display or a user terminal; the data transmitting and receiving module is connected with a database storing global positioning system (GPS) information, information geographic information system (GIS) and correlated heavy metal concentration information detected by all the monitoring terminals; a master control module of each monitoring terminal comprises an embedded processor, a clock and a GPRS sub-module; a detection module comprises a temperature sensor and a heavy metal electrochemical sensor array. According to the operating method, the temperature and the heavy metal concentration, monitored by the monitoring terminals, of a water environment are transmitted to the monitoring management system to be stored and displayed, and are compared with standard values and historical data through the data analysis processing module; when the polluted water quality is determined or the concentration of certain heavy metal is suddenly increased to a higher level, an alarm is given. According to the regional water environment heavy metal monitoring system and the operating method, the pollution of a water body is timely found by real-time sampling analysis and dynamic monitoring; the monitoring terminals are simple to network and easy to expand.
Owner:GUILIN UNIV OF ELECTRONIC TECH

Method for performing real-time regulation and control and digital management on water environment

The invention discloses a method for performing real-time regulation and control and digital management on a water environment, which belongs to the technical fields of water environment real-time simulation and management. The method comprises the following steps of: acquiring data; establishing a monitoring database; identifying specific pollution areas and pollution sources by establishing a water environment model; and providing a control measure for the concentration and the total emission of point-source and non-point-source pollutants in the specific areas, so that the whole drainage basin can be guided to execute the best management plan, a system for performing real-time regulation and control and digital management on the water environment is established by combining with an informationization mode to regulate and control the water quality of the river in real time, systematic technique support can be provided for drainage basin 'source control and emission reduction', water environment comprehensive treatment and quantitative management, and the application prospect is wide.
Owner:NORTH CHINA ELECTRIC POWER UNIV (BAODING)

Method for extracting copper from printed circuit board acidic spent etching solution and preparing poly ferric chloride

The invention relates to a method for extracting copper of a PCB acid etching waste liquid and preparing polyferric chloride, which comprises the following steps: the PCB acid etching waste liquid is electrolyzed directly and copper powder precipitated by electrolysis is reclaimed; reduced iron is added into a mixed solution after the electrolysis and copper sponge precipitated by replacement reaction is reclaimed; claimed crude copper is purified and prepared into copper powder products; the mixed solution after replacement reaction is added with ferric oxide or a substance containing Fe irons; the mixed solution mingled with the Fe irons is added respectively with a polymeric antioxidant and a stabilizer and simultaneously, the pH value of which is regulated with acid or alkali; and finally, the PFC is prepared. The method of the invention completely realizes reclamation and recycling of wastes and water environment treatment and finally 'zero' emission and has good environmental protection, simple preparation process, high economic benefit and wide application scope.
Owner:HUNAN VARY TECH

Water environment mobile robots

A water environment robotic system that includes a control station, an underwater robotic vehicle, and a water-surface robotic vehicle. The underwater robotic vehicle is in communication with the water-surface robotic vehicle and the water-surface robotic vehicle is in communication with the control station. Accordingly, the water-surface robotic vehicle can act as a relay between the control station and the underwater robotic vehicle. The water-surface robotic vehicle is further capable of detecting the position of the underwater vehicle and automatically adjusting the position of the underwater vehicle in order to maintain general vertical alignment between the two vehicles.
Owner:SAUDI ARABIAN OIL CO

Injection amphiphilic-microsphere-containing hyaluronic acid mixed gel and preparation method thereof

ActiveCN105126166AIrritant effectDifficult to assembleProsthesisCellulosePhosphate
The invention relates to injection amphiphilic-microsphere-containing hyaluronic acid mixed gel and a preparation method thereof. The microsphere material relates to amphiphilic materials of PLLA-PEG, PLGA, PLGA-PEG and the like. The molecular weight of PLLA or PLGA is 10,000-500,000, the molecular weight of PEG is 1,000-10,000, and in PLGA, LA / GA=90 / 10-10 / 90. The average grain diameter of the microsphere is 1-200 [mu[m, and the mass percent of the microsphere in the gel is 1-50%; the gel is made from hyaluronic acid, divinyl sulphone crosslinked hyaluronic acid, or glycidyl ether crosslinked hyaluronic acid, the molecular weight of the hyaluronic acid is 100,000-3,000,000, and the mass percent of the hyaluronic acid is 1-50%. The gel can be also made from animal-derived collagen, chitosan, amino acid cellulose and sodium alginate. The microsphere mixed gel is prepared in a sodium chloride solution or a phosphate buffered solution with the osmotic pressure of 250-350 mOsm / L and pH of 6.5-7.5. According to the invention, the amphiphilic microsphere is directly mixed with hyaluronic acid gel, can be uniformly distributed in the gel easily, and is unlikely to aggregate into blocks in the water environment of a human body after being injected.
Owner:IMEIK TECH DEV CO LTD
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