181 results about "Strychnos" patented technology

This invention discloses a method for manufacturing an insecticidal organic fertilizer. The fertilizer is composed of human or animal excrement, straw powder, tree leaves, wine lees, drug residues, sawdust, edible fungi residues, furfural residues, lime powder, fermentation agent, phosphorus- and potassium-leaching bacteria, tobacco powder, Ricinus communis leaf powder, Zanthoxylum cake powder, Datura and Strychnos nuxvomica. The fertilizer has such advantages as wide raw material resources, low cost, convenient usage, abundant nutrition, low fertilizer application amount, high efficiency, no toxicity, no pollution and no residues.

The invention relates to traditional Chinese medical liquor for external use for treating cervical spondylosi, periomethritis, hyperosteogeny, sciatica, rheumatism, rheumatoid disease, arthritis, soft tissue contusion, etc. The traditional Chinese medical liquor is intended to solve a problem that unsatisfied effect for treating the said diseases. A formula contains: cassia twig, Chinese parsnip root, notopterygium root, dahurian angelica root, radix bupleuri, root of kudzu vine, levisticum, clematis root, Tripterygium wilfordii Hook f, bark of ash, menispermaceae, cibotium rhizome, rhizoma zingiberis, monkshood, common fennel fruit, pseudo-ginseng, Ligusticum wallichii, safflower, Peach Seed, lumbricus, white batryticated silkworm, musk, borneol, Radix Astragali, Psoralea corylifolia, camphor, white peony root, Chinese angelica, Curculigo orchioides, Strychnos nuxvomica, centipede, cyathula root, ophidian, buck grass, Asarum Herb, speranskia herb, radix aconiti, tarragon, Chinese prickly ash, radix aconiti kusnezoffii, ephedra stem, ground beetle, scorpion, eucommia, myrrh, frankincense, pinellia ternate, licorice, garlic and capsicum. The traditional Chinese medical liquor has advantages of good curative effect, and low toxic and side effect.

The invention discloses a traditional Chinese medicine preparation for treating rheumatic cold pain in waists and legs, which is a pill prepared by the following traditional Chinese medicines with the weight portions: respective 1.5 portions of angelica, achyranthes, papaya, frankincense, myrrh, notopterygium, pubescent angelica, parsnip, Eupolyphaga sinensis Walker, immature tangerine, Dipsacus asperoides, asarum, safflower, whole worm, speranskia tuberculata, lycopodium clavatum and liquorice; respective 2 portions of eucommia and dried tangerine, respective 1 portion of szechuan lovage rhizome, angelica dahurica, nepeta, nianjian, difeng, drynaria, radix aconiti, radix gentianae macrophyllae, earthworm, anemarrhena, zaocys, millettia, pangolins, herba cistanches, rhizoma gastrodiae, zhuifengjian, woodwardia, red sage root, Mistletoe, and kusnezoff monkshood, and 40 portions of strychnos. The traditional Chinese medicine preparation expels wind and dispels cold, removes moisture and exercises channels, and nourishes liver and kidney. The traditional Chinese medicine preparation is used for deficiency of liver and kidney, anemofrigid-damp arthralgia, painful swelling of joint, limb numbness, waist and knee pain, and can be widely used in various pains such as rheumatoid arthritis, rheumatoid disease, hyperosteogeny, scapulohumeral periarthritis, sciatica, and gynecological lumbocrural pain, gastrointestinal disease, neck shoulder pain or lumbocrural pain and the like which are caused by rheumatic diseases.

The invention discloses a bone fracture setting ointment and method for preparing same. The bone fracture setting ointment is prepared by the following components: standard roots, Eupolyphaga, keel, crabs, wild grape root, Wu Chia Pee, alpine yallow herb, kusnezoff monkshood, Sichuan aconite root, strychnos nux-vomica, datura flower, pyrite, cassia twig, Asarum, monkshood, Eupatorium japonicum, borneol, gentiana macrophylla pall, notoginseng, buck grass, bark of eucommia, black bone, Drynaria, angelica, frankincense, myrrh, bletilla, aucklandia root, loranthus mulberry mistletoe, amber, elder, Vaseline, sesame oil, and wine. The method includes: placing the Vaseline into the wok, simmering, removing the fire and adding in benne oil and wine, and then adding the other components in the wok, stirring evenly and then spreading cool to form the bone fracture setting ointment. The invention can rapidly disperse the swelling and stop the pain, quicken the bone healing without any stimulation to the skin and any toxic side effects.

The invention discloses a strychnos alkaloid vesicle and a preparation method thereof, and a preparation containing the strychnos alkaloid vesicle and a preparation method thereof, and belongs to the field of medicinal preparations. The strychnos alkaloid vesicle is prepared from strychnos alkaloid, a nonionic surfactant and an additive. The strychnos alkaloid vesicle is preferably prepared into an external gel preparation. The strychnos transdermal administration external preparation has unique advantages on the medicament that: a novel vesicle administration system is applied; trandermal absorption of the medicament is increased; the clinical treatment effects are enhanced; and the toxic and side effects during oral administration and parenteral administration are avoided. The strychnos alkaloid vesicle can be applied to treatment of rheumatoid arthritis, ankylosing spondylitis, and the like.

The invention relates to a plaster for treating muscles and bones diseases, the bulk drugs are composed of Radix Astragali, Angelica sinensis, Ligusticum wallichii, white peony root, dipsacus asperoides, eucommia, Loranthus mulberry mistletoe, rhizoma drynariae, cibotium rhizome, achyranthes root, safflower, Saposhnikovia divaricata, Lycopodii herb, speranskia herb, Radix Angelicae Pubescentis, Radix clematidis, Aconitum carmichaeli debx, Aconitum Carmichaeli, Strychnos nuxvomica, ground beetle, pseudo-ginseng, keel, native copper, Radix Aucklandiae, angelica dahurica, Herba Asari, Chinese cassia tree, frankincense, borneol, yellow lead and sesame oil. The plaster has the advantages of convenient usage, substantial curative effect as well as small toxic and side effect; after tests of 310patients with muscles and bones diseases, the total effective rate reaches 96.1%.

An antineoplastic strychnos alkaloid liposome with 10w poison and high curative effect is proportionally prepared from strychnos alkaloid, phosphatide and cholesterol. Its preparing process by ammonium sulfate gradient method is also disclosed.

The invention discloses a special fertilizer for gingers and a preparation method thereof. The special fertilizer for the gingers comprises the following raw materials in parts by weight: 30-50 parts of human urine and stool, 25-45 parts of slaughterhouse waste, 15-20 parts of cottonseed meal, 10-15 parts of Chinese herbal dreg, 10-15 parts of straw, 8-16 parts of sawdust, 5-10 parts of peat moss, 5-10 parts of furfural slag, 6-12 parts of coal ash, 2-3 parts of strain powder, 20-30 parts of glauconite, 15-25 parts of diatomite, 2-3 parts of strychnos, 1-2 parts of daffodil, 2.5-3.5 parts of cassava leaf, 2-3 parts of larkspur, 1-2 parts of tripterygium, 12-16 parts of polyvinylpyrrolidone, 7-13 parts of sodium alginate, 16-22 parts of urea, 14-18 parts of monoammonium phosphate, 5-10 parts of potassium chloride, 1-2 parts of ferrous sulfate, 0.5-1 part of manganese sulfate and 0.5-1 part of borax. The special fertilizer for the gingers integrates organic fertilizer, inorganic fertilizer and manure fertilizer, has all-around and balanced nutrients, is high and lasting in fertilizer efficacy, and can inhibit and kill harmful bacteria in soil, enhance the disease resistance of the gingers, reduce the incidence of pests and diseases, improve physical and chemical properties of the soil, prevent soil hardening and increase the yield and the quality of the gingers so as to achieve aims of high yield, high quality and no pollution.

The invention discloses a method for obtaining purified total alkaloid of strychnos nux-vomica by removing partial strychnine in the total alkaloid of the strychnos nux-vomica, which comprises the following steps: extracting with a certain concentration of ethanol, dissolving the extract with hydrochloric acid ; adjusting the pH value to be alkaline after dissolving; carrying out extracting and pressure reduction on dichloromethane to remove solvent to obtain the total alkaloid of the strychnos nux-vomica; ultrasound dissolving total alkaloid powder of strychnos nux-vomica with ethanol; carrying out pressure reduction and concentration to a certain volume; centrifuging the concentrated solution, taking supernate, refrigerating and standing to remove precipitate; and drying the supernate to obtain the purified total alkaloid of strychnos nux-vomica. The content of strychnine in the total alkaloid of strychnos nux-vomica extracted by the method is remarkably reduced; and in addition, the method has safe extraction process, low cost and is beneficial to industrial scale production. Proved by the evaluation result of a pharmacological test, the effects of analgesia, anti-inflammation, immunity and antitumor activity of the purified total alkaloid of strychnos nux-vomica are remarkably superior to the effects of total alkaloid of strychnos nux-vomica and the toxicity is remarkably reduced.

The invention relates to a strychnos alkaloid vesicle and a preparation method thereof. The preparation method comprises the following steps: taking non-ionic surfactant span, Tween, single (double) alkyl polyglycerol ether, polyoxyethylene alkyl ether and the like as vesicle materials, and adding cholesterol, dicetyl phosphate and the like as stabilizers to prepare a novel targeting preparation with excellent preparation stability and easiness for industrialization.

The invention provides a Chinese traditional medicine composition for treating tumor and a preparing method thereof. The Chinese traditional medicine composition is prepared from radix curcumae, agrimony, trogopterus dung, white vitriol, saltpeter, resina toxicodendri, bitter orange and nux vomica powder, wherein the nux vomica poser is prepared from strychnos alkaloid and auxiliary material, and the auxiliary material is one or a mixture of some of dextrine, starch, mannite, microcrystalline cellulose and calcium bicarbonate. The composition has functions of supporting healthy energy, cleaning heat and toxins, and the like, can regulate immune function of an organism, reduce side and toxic effects and combine cancer prevention with cancer treatment, thereby improving the treating effect for tumor.

The invention discloses a blood-activating pain-relieving plaster. The blood-activating pain-relieving plaster is prepared from the following raw materials: 120 g of dragon's blood, 120 g of radix clematidis, 30 g of pseudo-ginseng, 30 g of fossil fragments, 60 g of ligusticum wallichii, 50 g of unprocessed strychnos, 30 g of radix aconiti kusenzoffii, 30 g of ground beeltle, 30 g of semen brassicae, 30 g of frankincense, 30 g of myrrh, 30 g of cortex cinnamomi, 30 g of clove, 50 g of rhizoma corydalis, 30 g of naze, 30 g of unprocessed pinellia ternate, 30 g of centipede, 30 g of garter snake, 20 g of leech, 30 g of pedate pinalliajackinthepulpit rhizome, 30 g of rhizoma sparganii, 30 g of curcuma zedoary, 60 g of rhizoma zingiberis, 50 g of cortex acanthopanacis, 30 g of euphorbia kansui, 50 g of berba aristolochiae mollissimae, 30 g of garden balsam stem, 30 g of rhizoma drynariae, 30 g of caulis spatholobi, 60 g of obscured homalomena rhizome, 30 g of euphorbia pekinensis, 30 g of flowers carthami, 30 g of ferula asafetida, 50 g of unprocessed jasmine, 10 g of radix angelicae, 30 g of liquorice, 10 g of asarum, 20 g of radix aucklandiae, 30 g of camphor, 10 g of borneol, 210 g of minium, and 500 ml of sesame oil. The blood-activating pain-relieving plaster is effective in treatment.

The invention discloses a medicament for treating rheumatism. The medicament is prepared from more than thirty herbal medicines such as radix aconiti lateralis preparata, dried ginger, notopterygium root, Radix Angelicae Pubescentis, Strychnos nuxvomica, etc. The medicament can effectively treat rheumatism, has no obvious toxic and side effects, and meanwhile has good curative effects on waist and leg pains caused by intervertebral disc protrusion and fracture pains.

The invention discloses an extraction, separation and purification method for strychnos total alkaloid, and belongs to the technical field of medicines. The method comprises but is not limited to the following steps of: treating strychnos coarse powder via an acid water extraction-organic solvent extraction method or an alkalization-organic solvent extraction method or an alcohol extraction-organic solvent extraction method to obtain the strychnos total alkaloid; purifying the total alkaloid via a solvent-stepwise extraction method or a column chromatography method or a hydrochloride-sulphate stepwise crystallization method; and then preparing via the hydrochloride-sulphate stepwise crystallization method or the column chromatography method to obtain strychnine having a purity of greater than 90%.

The invention discloses a sustained-release pill of total alkaloids from strychnos and a method for preparing the same. The sustained-release pill of total alkaloids from strychnos has high bioavailability, controllable release and long pain-relieving time, is taken for fewer times, is safe and reliable and can not cause pollution when being produced. The strychnine and strychnine is used as the active component of the sustained-release pill of total alkaloids from strychnos and is mixed with hydrophilic matrix material and hydrophobic matrix material which are used as matrix to prepare the sustained-release pill of total alkaloids from strychnos. The sustained-release pill of total alkaloids from strychnos comprises the following components by weight percent: 1-8 percent of the strychnine, 80-88 percent of hydrophilic matrix material and 10-12 percent of hydrophobic matrix material, wherein the hydrophilic matrix material is the mixture of polyethylene glycol 4000 and polyethylene glycol 6000, and the hydrophobic matrix material is stearic acid.

The invention discloses a rheumatism ostalgia plaster, which relates to the plaster for treating rheumatism ostalgia, wherein, the plaster comprises the following traditional Chinese medicinal materials by weight ratio: radix aconite, radix aconiti kusnezoffii, unprocessed Rhizoma Pinelliae, unprocessed Arisaema Consanguineum Schott, Asarum Herb, pericarpium zanthoxyli, clematis root, dahurian angelica root, grass-leaved sweetflag rhizome, turmeric, unprocessed Strychnos nuxvomica, ground beetle, frankincense, myrrh, speranskia herb, rosin, sesame oil and yellow lead; A preparation method comprises the following steps: A) selecting the above Chinese medicinal materials with high-quality, removing impurity and washing for standby; B) boiling the Chinese medicinal materials by steam to be steamed; C) drying or baking, crushing, wherein the fineness is 80-150 meshes; and D) rosin is placed in a stainless steel pot, completely melting rosin by slow fire, extinguishing fire and removing the pot from fire, standing for a while, and putting sesame oil and yellow lead to decoct into the paste. The present invention has the effects of expelling pathogenic cold from channels, promoting blood circulation to remove blood stasis, eliminating dampness and dispelling phlegm of the patch, and relaxing vein as well as relieving pain. The treatment is safe and has special efficacy, the cost is low, the treatment period is short, and statistics of 352 clinical treatment show that the total effective rate is 98.6%.

The invention relates to a method for preparing a plant medicament preventing and treating two spotted spider mite insects, comprising the following components: 3000 grams of dried tea, 5000 grams of tobacco leaves, 5000 grams of bead tree leaves, 5000 grams of strychnos, 5000 grams of zanthoxylum, 5000 grams of eucalyptus leaves and 3000 grams of sulfur. The method comprises the following steps: taking the dried tea, the tobacco leaves, the bead tree leaves, the strychnos, the zanthoxylum and the eucalyptus leaves proportionally, cutting up, completely combining together after crushing the sulfur, putting into a big iron kettle, adding warm water of 150 kilograms, decocting with strong fire for 50 minutes after soaking for 30 minutes, adding cold water of 5 kilograms, then decocting with strong fire for 10 minutes and filtering out decoction so as to obtain the plant medicament.

A traditional Chinese medicine for treating multiple osteopathies is disclosed by the invention, and is prepared by the following bulk drugs in parts by weight: 3-8 parts of ephedra stem, 3-8 parts of fried strychnos nuxvomica, 3-8 parts of borneol, 20-40 parts of pawpaw, 20-40 parts of cassia twig, 20-40 parts of silk-removing eucommia , 20-40 parts of achyranthes, 20-40 parts of oil-removing frankincense, 20-40 parts of oil-removing myrrh, 20-40 parts of notopterygium root, 20-40 parts of rhizoma homalomenae, 20-40 parts of schizophragma integrifolium, 20-40 parts of vinegar-treated native copper, 20-40 parts of saposhnikovia divaricata, 20-40 parts of licorice, 20-40 parts of cinnabar, 20-40 parts of amber, 20-40 parts of dragons blood, and 20-40 parts of safflower. The traditional Chinese medicine has a substantial curative effect on osteopathies including femur head necrosis, bone fracture, hyperosteogeny, cervical spondylosis, lumbar disc herniation and the like, and is short in healing time, good in effect and has no toxic and side effects.

The invention discloses a method for extracting, separating and purifying strychnine, and belongs to the technical field of medicine. The method includes but is not limited to the steps of: taking strychnos nux-vomica L., grinding the taken strychnos nux-vomica L. into coarse powder, performing extraction by using ethanol, combining extract, performing filtration, concentrating filtrate, and recovering the ethanol until no alcohol is smelt so as to obtain concentrated extract of total alkali of strychnos nux-vomica L.; acidifying the concentrated extract of total alkali of strychnos nux-vomicaL., performing extraction for impurity removal by adding an organic solvent, performing alkalinization on raffinate, and performing extraction by adding an organic solvent so as to obtain extract; adding the extract into a silica gel chromatographic column for elution, collecting the strychnine section of eluent, performing combining, concentration and drying, and performing purification by usinga recrystallization method to obtain the strychnine with a purity of 95% or more.

The invention relates to a composition and preparation method of a thin paste for treating pain and numbness. The method comprises the steps of: taking raw materials of long pepper, unprocessed radix aconite, unprocessed radix aconiti kusnezoffii, raw pinellia ternate, arisacma consanguineum schott, black pepper, asarum, angelica, raw frankincense, myrrh, speranskia tuberculata, strychnos, ligusticum wallichii, Chinese clematis, and radix angelicae pubescentis, later carrying out cleaning and airing, and then adding ethanol, carrying out impregnation at normal temperature and concentration by heating; taking and adding 654-II and chlorpheniramine to a container with alcohol for soaking for 2 days, heating for concentration, and then mixing and stirring the two types of soaking liquids after concentration with rosin which takes liquid shape by heating, and finally spreading paste to obtain the thin paste. Medicaments prepared by the method has the functions of relaxing muscle and activating blood, stopping pain and removing numbness, and particularly has very significant therapeutic effect on the hand-foot-waist-leg pain and numbness caused by various reasons such as cervical spondylosis, lumbar disc herniation, rheumatic and rheumatoid arthritis, and the like.

The invention discloses medicinal liquor for treating hyperosteogeny and belongs to the technical field of traditional Chinese medicines. The medicinal liquor is mainly prepared from a component A and a component B in a ratio of 1:(3-4), wherein the component A is prepared from seventeen medicines including Euphorbia cotinifolia, Thickleaf Croton root, himalayan teasel root, dahurian angelica root, sarcandra glabra, bark of Lindenleaf Torricellia, silktree albizia bark, Hiraute Shiny Bugleweek herb, crab, twig and leaf of Malabarnut, common Gendarussa herb, ground-ivy, herb of Bermudagrass, Japanese ophiorrhiza herb and the like; the component B is prepared from sixty medicines including amur corktree bark, eucommia bark, sappan wood, safflower, Chinese clematis root, twig and leaf of common Claoxylon, seed of Strychnos nuxvomica, cochinchina cudrania root, Tsoong Pellionia, stem of Climbing Entada, all-grass of Manybractelole Bugle, root of Ficus simplicissima and the like. The medicinal liquor is easy to prepare, the prepared medicinal liquor has effects of dispelling wind, eliminating dampness and promoting calcification of new bones, can effectively treat various clinical symptoms of a patient with hyperosteogeny, is low in recurrence rate and has no side effect.

The invention discloses an analgesic ointment with the function of relaxing tendons and activating collaterals, which is composed of the following ingredients: lovage, angelica, notopterygium, angelica, shenjincao, eucommia, clematis, achyranthes bidentata, rhizome rhizome, and bone supplement Fat, Aconitum, Speranthum, Nuxychia, Chuanduan, Safflower, Fangfeng, Wholeworm, Centipede, Frankincense, Myrrh, Dried Blood, Borneol, Camphor. The ointment of the present invention has strong penetrating power, quick drug effect, strong muscles and bones, expelling cold and dehumidification, promoting blood circulation, reducing swelling, relieving pain, dredging meridians, and can treat frozen shoulder, headache, swelling and numbness, lumbar disc disease caused by neck thrust disease. Sciatica caused by protrusion, numbness and pain in the waist and legs, lumbar muscle strain, ankylosing spondylitis, soft tissue contusion, unknown mass, mammary gland mass, tenosynovitis, rheumatic pain and other pain diseases have obvious curative effects.

The invention discloses a medicine for treating prolapse of lumbar intervertebral disc, which is mainly prepared by certain amounts of Cortex Acanthopanacis, Berba Aristolochiae Mollissimae, Strychnos nux-vomica seed, Rhizoma Atractylodis, Acorus tatarinowii, Flowers Carthami, Caesalpinia sappan, Liquorice, Fructus Psoraleae, Semen Cuscutae, tortoise plastron, Chinese wolfberry fruit, Aconitum carmichaeli, Cinnamon, Rhizoma Atractylodis Macrocephalae, Euryale ferox seed, Codonopsis pilosula, Angelica sinensis, Polygonum cuspidatum, Cortex Moutan, Rhizoma Alismatis, Radix Paeoniae Alba and Tribulus terrestris. The formula of the invention is formed by the inventor with clinical experience for many years and applies a unique manufacturing process. The medicine of the invention has the effects of tonifying kidney and spleen, replenishing Qi and blood, relieving wind, cold and dampness, clearing heat and resolving depression, promoting blood circulation and removing blood stasis, dredgingcollaterals and relieving pains and the like and is used to treat prolapse of lumbar intervertebral disc with remarkable effect and high cure rate.

The invention discloses an externally applied medicinal liquor for curing pain. The medicinal liquor is composed of smilax glabra, rhubarb root, strychnos nuxvomica, natural copper, myrrh, frankincense, rhzizoma drynariae, alangium lamarchii thwaites, dragon's blood, aconitum kusnezoffii, monkshood, artemisia rupestris, borneol and 40 degree pure rice wine. The preparation method comprises following steps: naturally drying and then grinding the medicinal materials mentioned above, putting the medicinal materials in a container, pouring into 40 degree pure rice wine for soaking, then filtering, finally adding borneol and stirring well so as to obtain the medicinal liquor. The pains caused by arthritis, numbness of teh extremities, periomethritis, inner rheumatism, hyperosteogeny, sciatica, traumatic injury or lumbar disc herniation, or the pains in waist and back, or the pains in cervical vertebra can be eliminated by continuously using (smearing) the medicinal liquor for 3 to 5 days, but if the pains are severer, it will take 10 to 15 days to cure the pains. Furthermore, the medicinal liquor has curative effects on pains caused by mosquito bites and various skin itches, has no side effects, and the curative cost is low.

The invention discloses a plaster for treating bone diseases and a preparation method thereof. The plaster is prepared from antler, prunella vulgaris, suberect spatholobus stem, airpotato yam rhizome,radix angelicae, white pepper, cortex phellodendri, oriental stephania root, red peony root, moutan bark, unprocessed rhizoma pinelliae, cassia twig, safflower, camphor, rheum officinale, rhizoma drynariae, ligusticum wallichii, cassia bark, buck grass, achyranthes root, radix angelicae sinensis, calamine, mollissima, rhizoma atractylodis, teasel root, unprocessed radix aconiti kusnezoffii, unprocessed radix aconite lateralis preparata, mulberry bark, licorice root, divaricate saposhnikovia root, adenophora root, pseudo-ginseng, clematis root, coptis root, banksia rose, centipede, vegetable sponge of luffa, Strychnos nuxvomica and unprocessed radix aconite. The plaster has the effects of dispelling wind and eliminating dampness, removing blood stasis and resolving static blood, warming and activating meridian, activating blood circulation, relieving swelling and pain, promoting metabolism and recovering the protrusion and puffiness, and can thoroughly treat neck, ridge and lumbar discherniation, bone hyperplasia, periarthritis of the shoulder, wind-cold-wetness bype of arthralgia, gouty arthritis, flashing belching, injuries from falls , fractures , contusions and strains and other bone diseases.

The invention discloses a traditional Chinese medicine composition used for treating facial neuritis, which comprises the following raw materials by weight part: 10-15 parts of windproof, 10-12 parts of notopterygium root, 6-12 parts of licorice, 5-8 parts of raw Radix Astragali, 6-10 parts of centipede, 2-5 parts of Strychnos nuxvomica and 3-5 parts of camphor. The traditional Chinese medicine composition has the advantages of fast effectiveness and good curative effect.

The invention relates to a preparation method of strychnine immune nanoparticles, and the preparation method comprises the following specific steps: step 1, dissolving carboxylated poly(ethylene glycol)-polylactic acid block copolymer and strychnine in an organic solvent, and then mixing with a polyvinyl alcohol aqueous solution to form a primary emulsion; step 2, removing the organic solvent andimpurities to obtain a strychnine nanoparticle concentrate; and step 3, sequentially adding a carbodiimide salt used as a carboxyl activation reagent and an anti-human-AFP (alpha-fetoprotein) monoclonal antibody to the strychnine nanoparticle concentrate, thus linking the carboxyl group on polyethylene glycol and the amino group of the anti-human-AFP monoclonal antibody by chemical coupling to obtain the strychnine immune nanoparticles. The preparation method provided by the invention has the advantages of simple process, high encapsulation rate, stable drug release and good drug ballability;and the obtained strychnine immune nanoparticles are used for preparing anti-tumor immune targeting drugs, and have the advantages of precise targeting drug accumulation in tumor tissue cells, stabledrug release, good anti-cancer effect, safety and the like.

The invention discloses a preparation method for an acupoint pain-relieving paste used for a cancer. The preparation method comprises the following steps: (1) weighing, by weight, 30 to 86 parts of Sichuan lovage rhizome, 15 to 35 parts of ground beetle, 5 to 7 parts of radix aconite, 20 to 89 parts of gamboges, 15 to 98 parts of radix aconiti kusnezoffii, 13 to 68 parts of gecko, 21 to 78 parts of airpotato yam rhizome, 15 to 76 parts of centipede, 15 to 98 parts of Strychnos nuxvomica, 13 to 98 parts of leech, 23 to 88 parts of bulb of edible tulip, 18 to 78 parts of frankincense, 15 to 98 parts of raw euphorbia, 13 to 68 parts of myrrh, 17 to 89 parts of Jackinthepulpit tuber, 18 to 78 parts of Chinese gall, 15 to 79 parts of Peking euphorbia root, 12 to 78 parts of realgar, 12 to 78 parts of dragon's blood and 8 to 65 parts of borneol and mixing and powdering the above-mentioned traditional Chinese medicines so as to obtain medicinal powder; and (2) adding ethanol, carrying out heating and reflux extraction to obtain extract, concentrating the extract into thick paste, adding Vaseline and carrying out uniform mixing. The paste is prepared from 20 carefully chosen traditional Chinese medicines, is capable of softening hardness, dissipating binds, clearing away toxic matters, relieving pain, freeing the channels, dispersing blood stasis and eliminating mass and has the advantages of no incurrence of addiction and dependence, obvious and long-lasting pain-relieving effect and no side effect.

A preparation method of crabapple flower nutrient fertilizer, which is composed of: loofah naan powder, corn leaf powder, straw powder, broad-leaved wood chips, buckwheat shell powder, wood ash powder, snail shell powder, shrimp shell powder, dried rabbit dung, dried sheep dung , barley straw powder, bran powder, rapeseed cake powder, cottonseed cake powder, nuxychon seed powder, neem leaf powder, bitter gourd powder, tripterygium twig powder, the percentages described are percentages by weight; the cost of the nutrient fertilizer cultivated by the invention Inexpensive, easy to obtain raw materials, simple preparation and preparation methods, rich in various nutrients in the ingredients, promote the rapid growth and development of crabapple flowers, strong growth, good disease prevention performance, and the blooming crabapple flowers are large in size, bright and attractive .

The invention relates to a preparation formulation for an externally applied liquid preparation prepared from total strychnos alkaloids, and preparation thereof. The preparation formulation is prepared from the total strychnos alkaloids and auxiliary materials such as a transdermal sorbefacient, a solvent, a humectant and an antiseptic according to certain proportion. The externally applied liquid preparation of the total strychnos alkaloids comprises a pharmaceutically described externally applied liquid preparation such as a spraying agent, a wet application, a liniment or a pigmentum, and is used for treating diseases such as injuries from falls, carbuncle-abscess pain, rheumatic obstinate paralysis, rheumatoid arthralgia and anesthesia and paralysis. The preparation can overcome the defect that people are easy to be poisoned when orally taking strychnos. As proved by research results, the preparation is safe and effective, is convenient and comfortable to use, has small skin irritation and low production cost, is easy to be accepted by patients, and can generate good social benefit and economic benefit.