1949 results about "Traumatic injury" patented technology

A cartilage plug, which is made from a biocompatible, artificial material, that is used to fill a void in natural cartilage that has been resected due to traumatic injury or chronic disease. Alternatively, the plug may be relied upon to anchor a flowable polymer to subchondral bone. The plug is prefabricatable in any size, shape, and contour and may be utilized either singly or in a plurality to fill any size void for any application. The plug may be formed of a laminated structure to match the physiological requirements of the repair site. A plurality of anchoring elements may share a single upper layer.

A cartilage plug, which is made from a biocompatible, artificial material, that is used to fill a void in natural cartilage that has been resected due to traumatic injury or chronic disease. Alternatively, the plug may be relied upon to anchor a flowable polymer to subchondral bone. The plug is prefabricatable in any size, shape, and contour and may be utilized either singly or in a plurality to fill any size void for any application. The plug may be formed of a laminated structure to match the physiological requirements of the repair site. A plurality of anchoring elements may share a single upper layer.

A cartilage plug, which is made from a biocompatible, artificial material, that is used to fill a void in natural cartilage that has been resected due to traumatic injury or chronic disease is disclosed. Alternatively, the plug may be relied upon to anchor a flowable polymer to subchondral bone. The plug is prebricatable in any size, shape, and contour and may be utilized either singly or in a plurality to fill any size void for any application. The plug may be formed of a laminated structure to match the physiological requirements of the repair site. Additionally, ridges may be formed about the periphery of each plug to facilitate its anchoring to surrounding cartilage, bone and / or adjacent plugs. A procedure for resecting damaged or diseased cartilage and for implanting a replacement plug or plugs according to this invention, as well as a set of instruments for effecting the procedure, and a self-contained system for orthopedic surgeons, which includes a variety of differently sized and shaped plugs, as well as a set of instruments for the procedure are also disclosed.< / PTEXT>

Devices and methods are disclosed for achieving chest drainage in humans or other animals. Chest drainage is often required following traumatic injury or surgery. The devices and methods disclosed herein are especially useful in the emergency, trauma surgery or military setting. The devices utilize a chest tube with a cutting distal end and a central blunt trocar. The blunt trocar or obturator shields the sharp cutting distal end of the chest tube until controllably retracted. Once the blunt trocar or obturator is retracted, the chest tube is advanced out through its sterile, protective package and into the patient. The blunt trocar is advanced back into its position to shield the sharp tip of the chest tube during patient insertion. The chest tube also includes a hold-down mechanism that is created by an adhesive seal to the patient's chest and ribbons or straps that are wrapped around the chest tube once it is correctly positioned. The straps include adhesive ends to grip the chest tube once the straps are in place.

The present invention discloses and describes pluripotent homozygous stem (HS) cells, and methods and materials for making same. The present invention also provides methods for differentiation of HS cells into progenitor (multipotent) cells or other desired cells, groups of cells or tissues. Further, the applications of the HS cells disclosed herein, include (but are not limited to) the diagnosis and treatment of various diseases (for example, genetic diseases, neurodegenerative diseases, endocrine-related disorders and cancer), traumatic injuries, cosmetic or therapeutic transplantation, gene therapy and cell replacement therapy.

The invention relates to a Chinese medicinal preparation for treating bone fracture, which is prepared from 84 raw medicinal materials such as radix astragali, Chinese angelica, rehmanniae vaporata, rehmanniae praeparatum, suberect spatholobus stem, human placenta and the like. The medicament can be made into an oral preparation and external application preparation. A preparation method comprises the following steps: preparing an aqueous extract of the raw medicinal materials, and preparing an oral solution and a spraying agent from the aqueous extract; and preparing extracting pulvis from the aqueous extract, and preparing granules, pills, medicinal granules, tablets or capsules from the extracting pulvis. Raw medicinal powder also can be ground into raw powder pulvis which can be prepared into the granules, the pills, the medicinal granules, the tablets or the capsules, or the raw powder pulvis is prepared into external application ointment. In addition, the raw medicinal materials also can be infused to form medicinal liquor. The Chinese medicinal preparation has good curative effect on bone fracture diseases of different types, is mainly used for treating different types of fracture, muscles and bones breakage, traumatic injury, new and old incised wound and gunshot wound, bleeding and blood stasis which are caused by traumatism and other symptoms, and has the obvious curative effect on rheumatoid arthritis. The Chinese medicinal preparation is prepared from pure Chinese medicaments, and has convenient use, safety, reliability, no toxic or side effect and long-term use.

A shoe is provided for improving use efficiency through reduction of neuromuscular fatigue. The shoe includes an upper having a generally horizontal bottom wall. The bottom wall includes an upper surface and a lower surface. The upper comprises a forward region having a forward center of loading and a rear region having a rear center of loading. The shoe further includes a sole comprising a midsole and an outsole. The midsole comprises a suspension element, which can have a generally elongated shape. The suspension element further has a center of compression, which is generally aligned with at least one of the first and second centers of loading of the upper. The shoe can have a hinge located within the sole for providing enhanced efficiency to the user. The hinge and suspension element(s) can take various forms. The position and structure of the hinge and suspension element(s) in relation to the midsole can take various forms as well. The biomechanical action of the heel element, forefoot element and hinge can be dynamically coupled to create a highly resilient suspension system with a low rate of loading throughout the stride, thus allowing a natural, “barefoot” gait for the wearer. As a result, the wearer experiences a significant reduction in jarring impacts for any phase of the stride, a corresponding reduction in cumulative fatigue and a lower rate of chronic or traumatic injury. A method of manufacturing a suspension element for a shoe is also provided, and includes the steps of providing a die having a length, a width and a thickness, the length accommodating a plurality of suspension elements; wrapping a plurality of coated or wetted fibers around the width of the die to form the suspension elements; drying or curing the fibers to a substantially integrated form; and separating the plurality of suspension elements into independent suspension elements.

Disclosed are a method and a corresponding pharmaceutical composition for treating damaged cartilage and subchondral bone. Neurogenic compounds in general and neuropeptides in particular have been found to be highly effective in stimulated repair of cartilage and bone damaged due to traumatic injury, ligament disease, and disuse. Preferred active ingredients for use in the method and corresponding pharmaceutical composition include calcitonin gene-related peptide (CGRP), cholecystokinin (CCK), dynorphin, enkephalin, galanin, neuropeptide Y (NPY), neurotensin, somatostatin, substance P (SP), thyrotropin-releasing hormone (TRH), vasoactive intestinal peptide (VIP).

An improved health and safety system for a table saw includes one or more of: a blade guard that protects the operator from the saw blade, and contains and collects sawdust; a proximity detector and emergency saw motor braking means for use in connection with such blade guard; an anti-kickback device for use in connection with such blade guard, a rip fence adapter for use in connection with such a blade guard, and hoses and fittings to connect the dust containment and collection system of said blade guard to a shop dust collection blower or vacuum system. The system protects the saw operator from potential traumatic injury to a hand, and from ingesting potentially carcinogenic sawdust.

This invention relates to cannabinoid-containing compositions, particularly cannabinoid-containing gel formulations and methods for the treatment of traumatic injury, e.g., strains, sprains and contusions, and disease conditions, e.g., arthritis, particularly osteoarthritis. The methods involve topically applying a cannabinoid or a cannabinoid-containing composition to a subject's skin near, or distant from, the area of the injury or the area affected by the disease condition, e.g., an arthritic joint. The cannabinoid-containing composition is preferably a pharmaceutically acceptable gel containing a therapeutically effective amount of a cannabinoid sufficient to alleviate the symptoms associate with the injury or disease condition.

The invention relates to a multi-effect external plaster and belongs to the field of external traditional Chinese medicines. The multi-effect external plaster is characterized by consisting of components A and B, wherein the component A comprises more than sixty Chinese herbs such as Chinese angelica, white paeony root, peach seed, beautiful sweetgum fruit, Indian iphigenia bulb, common selfheal fruit-spike, European verbena, twotooth achyranthes root, eucommia bark, centipede and the like, colophony, yellow lead and sesame oil; and the component B mainly comprises more than ten Chinese herbal medicinal ingredients such as white pepper, safflower, white mustard seed, medcinal evodia fruit, pyrite, dragon's blood, menthol, azone and the like, superfine natural magnetite powder and infrared ceramic powder. By combining the components A and B, the plaster of the invention not only has treatment effectiveness of the traditional plaster, but also has physiotherapy effectiveness of infrared rays, magnet therapy and the like. The multi-effect external plaster is suitable for various symptoms, such as traumatic injury, cervical spondylosis, spinal stenosis, scapulohumeral periarthritis, protrusion of lumbar vertebral disc, sciatica, lumbar muscle strain, arthritis, paraesthesia, facial nerve paralysis, facial nerve spasm, irregular menstruation and the like.

A shoe is provided for improving use efficiency through reduction of neuromuscular fatigue. The shoe includes an upper having a generally horizontal bottom wall. The bottom wall includes an upper surface and a lower surface. The upper comprises a forward region having a forward center of loading and a rear region having a rear center of loading. The shoe further includes a sole comprising a midsole and an outsole. The midsole comprises a suspension element, which can have a generally elongated shape. The suspension element further has a center of compression, which is generally aligned with at least one of the first and second centers of loading of the upper. The shoe can have a hinge located within the sole for providing enhanced efficiency to the user. The hinge and suspension element(s) can take various forms. The position and structure of the hinge and suspension element(s) in relation to the midsole can take various forms as well. The biomechanical action of the heel element, forefoot element and hinge can be dynamically coupled to create a highly resilient suspension system with a low rate of loading throughout the stride, thus allowing a natural, “barefoot” gait for the wearer. As a result, the wearer experiences a significant reduction in jarring impacts for any phase of the stride, a corresponding reduction in cumulative fatigue and a lower rate of chronic or traumatic injury. A method of manufacturing a suspension element for a shoe is also provided, and includes the steps of providing a die having a length, a width and a thickness, the length accommodating a plurality of suspension elements; wrapping a plurality of coated or wetted fibers around the width of the die to form the suspension elements; drying or curing the fibers to a substantially integrated form; and separating the plurality of suspension elements into independent suspension elements.

The invention discloses a pharmaceutical composition with effects of promoting blood circulation by removing blood stasis, anti-inflammatory and detumescence, and relieving pain and a preparation method thereof. The pharmaceutical composition is prepared from the following raw materials: 20-100 parts by mass of rhubarb, 20-110 parts by mass of gardenia and 10-100 parts by mass of baikal skullcap root. The preparation method of the pharmaceutical composition comprises the following steps: extracting the raw materials with water or ethanol for preparing the pharmaceutical composition, and then filtering and collecting filtrate to obtain the pharmaceutical composition. Clinical trials show that the pharmaceutical composition has favorable curative effect of relieving pains in neck and shoulders, waist and legs, joints and muscles caused by rheumatism, hyperosteogeny, traumatic injury, and the like.

The invention discloses detumescent and analgesic ointment for curing rheumatism and contusion and a preparation method thereof. The ointment is a pure herbal pharmaceutics, which is composed of monarch drugs, ministerial drugs, adjuvant drugs and conductant drugs. The preparation method comprises the following steps: placing 5kg of tung oil in a pan; grinding all traditional Chinese bug bulk pharmaceutical chemicals (BPC) into refined powder, wrapping the adjuvant drugs and the conductant drugs with gauzes, and placing into a frying pan for boiling; boiling with charcoal fire for 90min, putting the powder in to the frying pan after generating smokes, and boiling the mixture to obtain semi-creamy mixture; placing the ministerial drugs into the pan for even stirring to obtain semi-creamy mixture; taking the pan away from the fire and putting the monarch drugs into ointment for even stirring; placing 2.5kg of rosin into the ointment and evenly stirring to obtain the ointment, and pasting the ointment on kraft papers with 11 centimeters; and pressing the ointment on the kraft papers by a 6-centimeter iron module to obtain the ointment with diameter of 6 centimeters, and placing the obtained ointment on fixed patches. The detumescent and analgesic ointment for curing rheumatism and contusion can be used for stimulating the circulation of the blood and causing the muscles and joints to relax, relieving bruises and pains, and curing traumatic injuries and rheumatoid arthritis.

A fixator for use in the reconstruction of acute, chronic and traumatic injuries to the upper and lower extremities. The fixator has a unique clamping system that allows for the snapping in of pins and rails, and for multi-planar fixation of bones.

Compositions that include a clay such as kaolin dispersed in a liquid such as water may be useful for promoting the clotting of blood. The compositions may be in a liquid, gel, paste, foam, or another form. Uses may include treating a traumatic injury such as in injury caused by a bullet, an explosive, a blade etc., or an injury caused during a medical procedure such as surgery.

The invention provides methods for reducing traumatic injury through the use of ischemic conditioning.

The invention relates to a rheumatalgia-relieving plaster for treating trauma and process for preparation, wherein the plaster is prepared from 108 kinds of Chinese herbs including Sichuan aconite root, Kusnezoff monkshood root, jack-in-the-pulpit tuber, pinellia tuber, seed of nuxvomica, momordica seed, chaulmoogra seed, stinkweed root, pricklyash peel, pangolin scales, sargentgloryvine, root bark of chinese wolf berry, zedoary, shiny pricklyash, achyranthes and cyathula root, spicebush root and burred tuber.

The present invention discloses and describes pluripotent homozygous stem (HS) cells, and methods and materials for making same. The present invention also provides methods for differentiation of HS cells into progenitor (multipotent) cells or other desired cells, groups of cells or tissues. Further, the applications of the HS cells disclosed herein, include (but are not limited to) the diagnosis and treatment of various diseases (for example, genetic diseases, neurodegenerative diseases, endocrine-related disorders and cancer), traumatic injuries, cosmetic or therapeutic transplantation, gene therapy and cell replacement therapy.

Devices and methods are disclosed for achieving chest drainage in humans or other animals. Chest drainage is often required following traumatic injury or surgery. The devices and methods disclosed herein are especially useful in the emergency, trauma surgery or military setting. The devices utilize a chest tube with a cutting distal end and a central blunt trocar. The blunt trocar or obturator shields the sharp cutting distal end of the chest tube until controllably retracted. Once the blunt trocar or obturator is retracted, the chest tube is advanced out through its sterile, protective package and into the patient. The blunt trocar is advanced back into its position to shield the sharp tip of the chest tube during patient insertion. The chest tube also includes a hold-down mechanism that is created by an adhesive seal to the patient's chest and ribbons or straps that are wrapped around the chest tube once it is correctly positioned. The straps include adhesive ends to grip the chest tube once the straps are in place.

The present invention provides compositions and methods for the treatment of central nervous system damage in a subject. More particularly, the invention provides a combination therapy for the treatment of a central nervous system ischemic condition or a central nervous system traumatic injury comprising the administration to a subject of a potassium ion channel modulator in combination with a cyclooxygenase-2 selective inhibitor.

The present invention features the use of selected complement activation inhibitor(s) for treating an individual who has suffered a severe injury. The complement activation inhibitor acts at or above the level of C3 activation and does not significantly deplete or irreversibly inhibit complement activation. Also provided are compositions and methods for repleting and / or enhancing complement activation capacity in a subject who has suffered a traumatic injury.

The present invention discloses a method for the occlusion of blood vessels or fluid vessels to stop the flow of blood or fluid during elective or emergency surgical procedures or following traumatic injury. This invention also encompasses a medical device or tool for occluding, reducing, or controlling blood flow or fluid flow. In this invention, a plug or blockade is formed to occlude, reduce, or control blood flow or fluid flow when magnetic microparticles, nanoparticles, or colloids are administered into a blood vessel or fluid vessel, and an external magnetic field source is placed at the desired site near or above the path of the blood stream or fluid flow. Removal of said external magnetic field source would result in the redispersion of the microparticle blockade and resumption of the flow.

An improved health and safety system for a table saw includes one or more of: a blade guard that protects the operator from the saw blade, and contains and collects sawdust; a proximity detector and emergency saw motor braking means for use in connection with such blade guard; an anti-kickback device for use in connection with such blade guard, a rip fence adapter for use in connection with such a blade guard, and hoses and fittings to connect the dust containment and collection system of said blade guard to a shop dust collection blower or vacuum system. The system protects the saw operator from potential traumatic injury to a hand, and from ingesting potentially carcinogenic sawdust.

The present invention provides a composition, and a method of use thereof for treating connective tissue damage in man and in animals, which comprises a therapeutically effective amount of chondroitin sulfate, N-acetyl D-glucosamine, and hyaluronan (hyaluronic acid). Particularly, the present invention provides a composition, and a method of use thereof, for treating connective tissue damage including, but not limited to, arthritic disease, osteoarthritis, rheumatoid arthritis, osterochondrosis dessicans, cartilage damage, joint injury, joint inflammation, joint synovitis, degenerative joint disease (DJD), post surgical DJD, traumatic injury, fracture, tendon damage, ligament damage, skeletal damage, musculoskeletal damage, fiber damage, adipose tissue damage, blood cell damage, and plasma damage. Compositions for delivery of the present invention include those for parenteral, oral, and transmucosal delivery and for direct surgical placement onto the affected tissues.

The present invention provides methods for conferring a neuroprotective effect on a population of cells in a subject following a traumatic injury to the central nervous system. Specifically, the methods of the invention provide for the administration of a progestin or progestin metabolite following a traumatic brain injury. The progestin or progestin metabolite is administered at therapeutically effective concentrations that produce a neuroprotective effect (i.e., a decrease in the loss of neuronal activity) and reduces and / or prevents the various physiological events leading to neurodegeneration, such as, cerebral edema and the immune / inflammatory response.

A method of producing a homogenous population of homozygous stem (HS) cells pre-selected for immunotype and / or genotype from donor cells is described herein. The invention relates to methods of using immunohistocompatible HS cells for diagnosis, therapeutic and cosmetic transplantation, and the treatment of various genetic diseases, neurodegenerative diseases, traumatic injuries and cancer. The invention further relates to methods for using histocompatible HS stem cells pre-selected for a non-disease genotype for prophylactic and therapeutic intervention including, but not limited to, therapeutic and cosmetic transplantation, and the treatment of various genetic diseases, neurodegenerative diseases, and cancer. Furthermore, the invention relates to a catalogued transplant depository of HS cells derived from multiple donors, each of the HS cells being homozygous for a unique HLA haplotype, for the purpose of having a constant, reliable, comprehensive supply of immunohistocompatible cells for diagnosis, treatment and / or transplantation.

The invention relates to the technical field of traditional Chinese medicines, and in particular to a traditional Chinese medicine unguent for promoting blood circulation to remove meridian obstruction and a preparing method of the traditional Chinese medicine unguent. The traditional Chinese medicine unguent for promoting blood circulation to remove meridian obstruction mainly comprises the following raw materials: drynaria rhizome, radix clematidis, pawpaw, notopterygium root, radix angelicae tuhuo, radix saposhnikoviae, ligusticum wallichii, garden balsam stem, lycopodium clavatum, radix dipsaci, medicinal cyathula root, safflower carthamus, eucommia ulmoides, angelica sinensis, cassia twig, the root of common peony, rheum officinale, asarum, frankincense, myrrh, monkshood, radix aconiti agrestis, acacia catechu, ephedra, ground beeltle, lumbricus, stir-baked squama manitis, scorpio, pseudo-ginseng, daemonorops draco and borneol. The traditional Chinese medicine unguent is scientific in formula, and has the effects of promoting circulation and removing stasis, clearing and activating the channels and collaterals, dispelling wind to eliminate dampness, relieving swelling and pains and promoting reunion of fractured bones. The traditional Chinese medicine unguent is used for treating diseases such as lumbar disc herniation, traumatic injuries, fractures, osteoproliferation, arthritis, numbness of limb and femoral head necrosis, untoward effects are avoided, the traditional Chinese medicine unguent is safe, free of toxic and side effects and rapid in effect taking, treating both manifestation and root causes of the diseases, has a wide application prospect and market potential; and the total effective rate reaches 100%.

This invention relates to cannabinoid-containing compositions, particularly cannabinoid-containing gel formulations and methods for the treatment of traumatic injury, e.g., strains, sprains and contusions, and disease conditions, e.g., arthritis, particularly osteoarthritis. The methods involve topically applying a cannabinoid or a cannabinoid-containing composition to a subject's skin near, or distant from, the area of the injury or the area affected by the disease condition, e.g., an arthritic joint. The cannabinoid-containing composition is preferably a pharmaceutically acceptable gel containing a therapeutically effective amount of a cannabinoid sufficient to alleviate the symptoms associate with the injury or disease condition.