46 results about "Excellent preparation" patented technology

Disclosed is a preparation for external application to skin, which contains a branched acylcarnitine and has excellent preparation stability. Also disclosed is a cosmetic preparation. Specifically disclosed is a preparation for external application to skin, which is characterized by containing a carnitine derivative represented by Formula (1) and / or a carnitine derivative salt represented by Formula (2) and an amphoteric surfactant. In Formula (1), R1 and R2 independently represent an optionally branched, saturated or unsaturated aliphatic hydrocarbon group having 1-18 carbon atoms. In Formula (2), R1 and R2 are as defined in Formula (1); X- represents a specific anion; and Y+ represents a specific cation.

The invention relates to a tebipenem pivoxil-containing oral preparation and a preparation method of the tebipenem pivoxil-containing oral preparation. The preparation provided by the invention consists of tebipenem pivoxil and a pharmaceutic adjuvant as the active components. The pharmaceutic adjuvant contains beta-cyclodextrin. The tebipenem pivoxil oral preparation provided by the invention overcomes the defects that the grit feeling is produced when the tebipenem pivoxil oral preparation is taken, the patient compliance is poor and the preparation technology is complicate in the prior art, so that the tebipenem pivoxil oral preparation is an excellent preparation with good taste, high dissolvability, good stability and simple preparation technology.

The invention discloses a gastrodin multiphase liposome injection and a preparation method thereof. Gastrodin, soybean phosphatidylinositol, cholesterol, Twain 80, polyoxyethylene 40, hydrogenated castor oil, trehalose and EDTA-2Na which have specific weight ratios are prepared into the gastrodin multiphase liposome injection. The gastrodin multiphase liposome injection provided by the invention has excellent preparation stability and meets the demand of intravenous injection; after the gastrodin multiphase liposome injection is stored for a long time, the excellent encapsulation of the liposome is kept; the solubility of gastrodin is increased; the quality of preparation product is increased; the toxic side effect is reduced; the retention time of medicine in systemic circulation is increased; the bioavailability of the medicine is increased; the curative effect is obviously increased; and the preparation method is simple and is suitable for industrial production in bulk.

An O / W emulsion composition having excellent preparation stability, feeling of use and ultraviolet light blocking properties. The O / W emulsion composition has the first oil phase and second oil phase described below, which are separately dispersed in a water phase. (i) a first oil phase which is formed by using a polyoxyethylene / polyoxyalkylene alkyl ether block polymer represented by general formula (1) or (2) as an emulsifying agent, and contains an organic ultraviolet absorbent, while having an average particle diameter of not more than 700 nm (ii) a second oil phase which is formed by using an alkyl-modified carboxyvinyl polymer as an emulsifying agent, and contains a silicone oil R1O-(PO)m-(EO)n-H (1) (In the formula, R1 represents a hydrocarbon group having 16-18 carbon atoms; PO represents an oxypropylene group; EO represents an oxyethylene group; PO and EO are added in blocks; and m and n respectively represent average mole numbers of added PO and EO and satisfy 70 > m > 4, 70> n > 10 and n > m.) R2O-(AO)p-(EO)q-R3 (2) (In the formula, R2 and R3 may be the same or different and each represents a hydrocarbon group having 1-4 carbon atoms; AO represents an oxyalkylene grouphaving 3-4 carbon atoms; EO represents an oxyethylene group; AO and EO are added in blocks; and p and q respectively represent average mole numbers of added AO and EO and satisfy 1 = p = 70, 1 = q = 70 and 0.2 < (q / (p + q)) < 0.8.)