11675 results about "Chemical stability" patented technology

A method for determining conditions for forming a dielectric SiOCH film, includes: (i) forming a dielectric SiOCH film on a substrate under conditions; (ii) evaluating the conditions using a ratio of Si—CH3 bonding strength to Si—O bonding strength of the film as formed in step (i); (iii) if the ratio is 2.50 % or higher, confirming the conditions, and if the ratio is less than 2.50 %, changing the conditions by changing at least one of the susceptor temperature, the distance between upper and lower electrodes, the RF power, and the curing time; and (iv) repeating steps (i) to (iii) until the ratio is 2.50 % or higher.

An inhalable unit dose liquid formulation containing SAE-CD and corticosteroid is provided. The formulation is adapted for administration to a subject by nebulization with any known nebulizer. The formulation can be included in a kit. The formulation is administered as an aqueous solution or concentrated composition. The formulation is employed in an improved nebulization system for administering corticosteroid by inhalation. SAE-CD present in the formulation significantly enhances the chemical stability of corticosteroid, such as budesonide. A method of administering the formulation by inhalation is provided. The formulation can also be administered by conventional nasal delivery apparatus. The formulation is prepared by mixing SAE-CD, in solid or liquid (dissolved) form, with an inhalable suspension-based unit dose formulation.

Disclosed are ionically conductive membranes for protection of active metal anodes and methods for their fabrication. The membranes may be incorporated in active metal negative electrode (anode) structures and battery cells. In accordance with the invention, the membrane has the desired properties of high overall ionic conductivity and chemical stability towards the anode, the cathode and ambient conditions encountered in battery manufacturing. The membrane is capable of protecting an active metal anode from deleterious reaction with other battery components or ambient conditions while providing a high level of ionic conductivity to facilitate manufacture and / or enhance performance of a battery cell in which the membrane is incorporated.

Disclosed are ionically conductive composites for protection of active metal anodes and methods for their fabrication. The composites may be incorporated in active metal negative electrode (anode) structures and battery cells. In accordance with the invention, the properties of different ionic conductors are combined in a composite material that has the desired properties of high overall ionic conductivity and chemical stability towards the anode, the cathode and ambient conditions encountered in battery manufacturing. The composite is capable of protecting an active metal anode from deleterious reaction with other battery components or ambient conditions while providing a high level of ionic conductivity to facilitate manufacture and / or enhance performance of a battery cell in which the composite is incorporated.

Disclosed are ionically conductive composites for protection of active metal anodes and methods for their fabrication. The composites may be incorporated in active metal negative electrode (anode) structures and battery cells. In accordance with the invention, the properties of different ionic conductors are combined in a composite material that has the desired properties of high overall ionic conductivity and chemical stability towards the anode, the cathode and ambient conditions encountered in battery manufacturing. The composite is capable of protecting an active metal anode from deleterious reaction with other battery components or ambient conditions while providing a high level of ionic conductivity to facilitate manufacture and / or enhance performance of a battery cell in which the composite is incorporated.

The present invention provides means to improve the chemical stability of aqueous, parenteral pharmaceutical compositions comprising a polypeptide and glycerin. Reactive aldehydes are identified in commercial glycerins, and means for reducing such are provided. Convenient means are provided to assay for reactive aldehydes in glycerin, and a strong linear correlation between the level of reactive aldehydes in glycerin and chemical stability of compositions comprising a polypeptide and glycerin is demonstrated. The invention includes aqueous compositions comprising a polypeptide and glycerin having improved chemical stability compared to compositions previously known.

Provided with a glass composition including a network-former oxide composed of any one of or both of B2O3 and V2O5 of 20-80% by weight, ZnO of 0-60% by weight and BaO of 0-80% by weight, wherein at least one of ZnO and BaO is included as an essential ingredient. The present invention is a glass material for use in sealing, which is of lead-free series, can be used for sealing at a low processing temperature and within a wide temperature range, has a low thermal expansion coefficient, superior adhesion, superior sealing processability, superior adherence, superior chemical stability, superior strength and the like and comprises sufficient practical performance to substitute for lead glass.

An inhalable formulation containing SAE-CD and corticosteroid is provided. The formulation is adapted for administration to a subject by nebulization with any known nebulizer. The formulation can be included in a kit. The formulation is administered as an aqueous solution, however, it can be stored as a dry powder, ready-to-use solution, or concentrated composition. The formulation is employed in an improved nebulization system for administering corticosteroid by inhalation. SAE-CD present in the formulation significantly enhances the chemical stability of budesonide. A method of administering the formulation by inhalation is provided. The formulation can also be administered by conventional nasal delivery apparatus.

The invention discloses surface anti-corrosion sol for an aeronautic aluminum alloy material and a treatment method thereof in the technical field of aluminum alloy surface treatment. The sol comprises the following components in percentage by weight: 1-15 percent of organosiloxane, 45-93 percent of organic solvent, 0.1-10 percent of additive, 0.5-10 percent of rare earth salt, 5-50 percent of deionized water and 0.1-5 percent of catalyst. In the invention, a coating with a compact netlike crosslinking structure is formed on the surface of an aluminum alloy matrix and has high chemical stability and thermal stability, so that influence of an external acidic and alkaline environment and temperature variation on the coating can be resisted; and the coating has higher mechanical strength, rain washing resistance, friction resistance and scratch resistance. The technical method is simple, is easy and convenient to operate, does not have high requirement on equipment and is environmentally-friendly and pollution-free.

The present invention relates to an immunoglobulin-binding protein, wherein at least one asparagine residue has been mutated to an amino acid other than glutamine or aspartic acid, which mutation confers an increased chemical stability at pH-values of up to about 13-14 compared to the parental molecule. The protein can for example be derived from a protein capable of binding to other regions of the immunoglobulin molecule than the complementarity determining regions (CDR), such as protein A, and preferably the B-domain of Staphylococcal protein A. The invention also relates to a matrix for affinity separation, which comprises an immunoglobulin-binding protein as ligand coupled to a solid support, in which protein ligand at least one asparagine residue has been mutated to an amino acid other than glutamine.

The invention discloses a large-scale preparation method of a transparent super-hydrophobic / super-amphiphobic coating. The method comprises the steps of ultrasonically dispersing nano particles into an alcohol-water mixed system and carrying out hydrolysis and condensation reaction on the nano particles and fluoride-free or fluorine-containing organosilane under the acid or alkali catalysis action to prepare a transparent suspension liquid of a fluoride-free or fluorine-containing organosilane polymer-nano particle compound; and applying the transparent suspension liquid of the compound on the surface of a substrate material through spraying or dip-coating to obtain the transparent super-hydrophobic / super-amphiphobic coating with good performance. Preparation of the transparent super-hydrophobic / super-amphiphobic coating of 10-100m<2> can be completed within an hour; large-scale preparation of the large-area transparent super-hydrophobic / super-amphiphobic coating is achieved for the first time; the preparation method is low in cost and simple in process; and the prepared coating has excellent super-hydrophobic or super-amphiphobic property, relatively good mechanical stability, chemical stability and environment stability, and has a wide application prospect.

Multifunctional liquid rubber spray coating comprises components of A, B, wherein A component comprises liquid rubber asphalt emulsion whose solid content is 50-75%, wherein 2-65% rubber elusion content, 30-97% asphalt elusion content, 0.0-5.0% carbon black, 0.0-6.0% ultra-fine powder, 0.025-2.50% anion dispersing agent and 0.025-3.00% anion surface activator, which is waterborne spray coating, and B component is water solution which comprises 3.0-18.0% concentration calcii chloridum (89.0-99.2%), sodium chloride (0.50-4.0%) and composite aluminum iron polymer (0.3-7.0%). The two components are sprayed on the same basal plane through adopting a double-component airless spraying device to form a gelatin film with 0.5-4mm after 3-5 seconds solidification, which has the characteristics of strong bonding, temperature resistance, weather resistance, and excellent chemical stability, heat insulation and puncture resistance. The A component can be individually sprayed, or can be combined with the double components.

The present invention is a gas component sensor comprising novel electrolyte compositions. The electrolyte compositions in bulk, sintered or thin film embodiments are capable of forming with different-metal sensing and reference electrodes a highly stable gas oxide sensors. The novel electrolyte composition changes electrochemical reactions at the sensing and reference electrodes and the overall reaction of the electrodes and electrolyte. The novel electrolyte compositions have: (1) excellent chemical stability and thermal compatibility as to the electrodes and a preferred ceramic substrate, (2) excellent chemical stability with the environment as to the reference and sensing electrodes, which need not be sealed against the atmosphere to be sensed, (3) effective adherence to the substrate and electrode metals.

The present invention relates to the use of an alkali-stable protein, wherein at least one asparagine residue has been mutated to an amino acid other than glutamine or aspartic acid, which mutation confers an increased chemical stability at pH-values of up to about 13-14 compared to the parental molecule. The protein can for example be derived from a protein capable of binding to other regions of the immunoglobulin molecule than the complementarity determining regions (CDR), such as protein A, and preferably the B-domain of Staphylococcal protein A. The invention also relates to a matrix for affinity separation, which comprises an immunoglobulin-binding protein as ligand coupled to a solid support, in which protein ligand at least one asparagine residue has been mutated to an amino acid other than glutamine.

Pharmaceutical formulations, kits and vessels are provided for delivering decitabine to a patient suffering from a disease in need of treatment with decitabine. The pharmaceutical formulation comprises decitabine solvated in a non-aqueous solvent that comprises glycerin, propylene glycol, polyethylene glycol, or combinations. Such formulations are more chemically stable than conventional liquid formulations of decitabine containing more than 40% water in volume. The pharmaceutical formulations can be used for any disease that is sensitive to the treatment with decitabine, such as hematological disorders and cancer.

A transistor includes a semiconductor channel disposed nearby a gate and in an electrical path between a source and a drain, wherein the channel and at least one of the source or the drain are separated by an interface layer so as to form a channel-interface layer-source / drain junction in which a Fermi level of the semiconductor channel is depinned in a region near the junction and the junction has a specific contact resistance of less than approximately 1000 Ω-μm2. The interface layer may include a passivating material such as a nitride, a fluoride, an oxide, an oxynitride, a hydride and / or an arsenide of the semiconductor of the channel. In some cases, the interface layer consists essentially of a monolayer configured to depin the Fermi level of the semiconductor of the channel, or an amount of passivation material sufficient to terminate all or a sufficient number of dangling bonds of the semiconductor channel to achieve chemical stability of the surface. Also, the interface layer may include a separation layer of a material different than the passivating material. Where used, the separation layer has a thickness sufficient to reduce effects of metal-induced gap states in the semiconductor channel.

Disclosed are ionically conductive composites for protection of active metal anodes and methods for their fabrication. The composites may be incorporated in active metal negative electrode (anode) structures and battery cells. In accordance with the invention, the properties of different ionic conductors are combined in a composite material that has the desired properties of high overall ionic conductivity and chemical stability towards the anode, the cathode and ambient conditions encountered in battery manufacturing. The composite is capable of protecting an active metal anode from deleterious reaction with other battery components or ambient conditions while providing a high level of ionic conductivity to facilitate manufacture and / or enhance performance of a battery cell in which the composite is incorporated.

Disclosed are ionically conductive membranes for protection of active metal anodes and methods for their fabrication. The membranes may be incorporated in active metal negative electrode (anode) structures and battery cells. In accordance with the invention, the membrane has the desired properties of high overall ionic conductivity and chemical stability towards the anode, the cathode and ambient conditions encountered in battery manufacturing. The membrane is capable of protecting an active metal anode from deleterious reaction with other battery components or ambient conditions while providing a high level of ionic conductivity to facilitate manufacture and / or enhance performance of a battery cell in which the membrane is incorporated.

The invention discloses high-strength lithium disilicate glass ceramic and a preparation method thereof. The glass ceramic comprises the following chemical components in percentage by weight: 59-80% of SiO2, 10-18% of Li2O, 0.1-14% of MgO, 0-15% of Al2O3, 1-8% of P2O5, 0-5% of Na2O, 0-7% of CaO, 0-9% of K2O, 0.5-8% of stabilizer and 0-10% of colorant, wherein the stabilizer is selected from one or more of ZrO2, SrO, BaO and Y2O3, and the colorant is selected from one or more of Eu2O3, CeO<+>, Tb4O7, La2O3, Ta2O5, MnO2 and Fe2O3. The lithium disilicate glass ceramic is a material which contains a residual glass phase, a Li2Si2O5 principal crystalline phase and a small quantity of Li3PO1, quartz, cristobalite, zirconium oxide or magnesium-aluminum silicate phase and is prepared by controlling nucleation and crystallization processes after carrying out heat treatment on lithium disilicate matrix glass. The lithium disilicate glass ceramic is very high in bending strength and fracture toughness and favorable in translucence and chemical stability and can serve as a full-ceramic dental material applied to the field of dental restoration.

Disclosed is a secondary battery comprising a cathode, an anode, a separator and an electrolyte, wherein the electrolyte comprises a eutectic mixture formed of: (a) an amide group-containing compound, and (b) an ionizable lithium salt, and the anode comprises a metal or metal oxide having a potential vs. lithium potential (Li / Li+) within electrochemical window of the eutectic mixture. An electrolyte for a secondary battery comprising the eutectic mixture is also disclosed. Since the secondary battery uses a eutectic mixture as an electrolyte in combination with an anode having a potential vs. lithium potential (Li / Li+) within the electrochemical window of the eutectic mixture, it solves the problems occurring in a conventional battery using a eutectic mixture as an electrolyte, such problems including decomposition of an electrolyte and degradation of the quality of a battery. Also, due to the thermal and chemical stability, high conductivity and a broad electrochemical window of a eutectic mixture, it is possible to improve the quality as well as safety of a battery.

Disclosed are ionically conductive composites for protection of active metal anodes and methods for their fabrication. The composites may be incorporated in active metal negative electrode (anode) structures and battery cells. In accordance with the invention, the properties of different ionic conductors are combined in a composite material that has the desired properties of high overall ionic conductivity and chemical stability towards the anode, the cathode and ambient conditions encountered in battery manufacturing. The composite is capable of protecting an active metal anode from deleterious reaction with other battery components or ambient conditions while providing a high level of ionic conductivity to facilitate manufacture and / or enhance performance of a battery cell in which the composite is incorporated.

The invention belongs to the technical field of the preparation of graphene quantum dots (GQDs), and particularly relates to a method for preparing fluorescent graphene quantum dots with controllable oxidation degree and fluorescence by a solvothermal method. According to the technical scheme, the method comprises the following steps of: 1, preparing graphene oxide; 2, preparing green fluorescent graphene quantum dots by a single-step method starting from the graphene oxide; and 3, preparing the fluorescent graphene quantum dots with the controllable oxidation degree by a column chromatographic separation method. According to the method, the sizes and surface oxidation degree of the graphene quantum dots can be controlled under the synthetic condition, so that the fluorescent properties and surface chemical characteristics of the graphene quantum dots are controlled. The prepared graphene quantum dots are high in chemical stability and biocompatibility, low in biotoxicity, and high in property of applicable upconversion fluorescence, matt and the like and bleaching performance. By the excellent properties, the graphene quantum dots have a wide application range in aspects of biological imaging, photovoltaic devices and sensors, and are novel promising fluorescent nano materials.

An electrolyte membrane includes a cross-linked reaction product of a benzoxazine monomer and a cross-linkable compound. The electrolyte membrane is impregnated with 300 to 600 parts by weight of phosphoric acid based on 100 parts by weight of the electrolyte membrane, and has a yield strain 0.5% or less, and a yield stress 0.3 Mpa or less. The cross-linked material has a strong acid trapping ability with respect to the benzoxazine compound and excellent mechanical properties due to a cross-linkage. Also, the solubility of the cross-linked material in polyphosphoric acid is low, thereby showing excellent chemical stability. Accordingly, when the cross-linked material is used, an electrolyte membrane having an excellent liquid supplementing ability and excellent mechanical and chemical stability at a high temperature can be obtained. The cross-linked material can be obtained by a simple polymerization process by combining a benzoxazine monomer and a crosslinkable compound and by using heat instead of using a polymerization initiator or a cross-linking agent.

A ceramic material has particular utility as a thermal insulating or thermal barrier coating on metallic substrates. The ceramic material includes gadolinia and hafnia, preferably forming gadolinia-hafnia. This material exhibits chemical stability, thermal stability and thermal insulating properties superior to those of currently used thermal barrier ceramics, and also provides resistance to sintering and erosion comparable to currently used ceramics. A preferred material has between about 3-70 mol. % hafnia, balance hafnia.

The invention discloses a PVC foam wood / plastic composite material and relates to the technical field of composite materials. The PVC foam wood / plastic composite material is made from the following raw materials in parts by weight: 20-70 parts of PVC resin powder, 0-55 parts of wood flour, 5-40 parts of calcium carbonate powder, 0.1-0.5 part of sodium bicarbonate, 0.3-0.6 part of an azo-compound or hydrazine derivative, semicarbazide compound or nitroso-compound, 2-10 parts of a foaming regulator, 1.5-6 parts of a composite stabilizer, 0.7-2.1 parts of a lubricant, 0.5-1.2 part of soybean oil, 2.5-5.5 parts of an impact modifier, and 0.5-3 parts of a processing agent. The PVC foam wood / plastic composite material provided by the invention has the advantages of strong chemical stability, high strength, resistance to acid / alkaline corrosion, resistance to water seepage, flame retardancy and low cost.

In one aspect, pharmaceutical compositions comprising dispersions of an acid-sensitive drug and a neutral dispersion polymer are disclosed. The acid-sensitive drug has improved chemical stability relative to dispersions of the drug and acidic polymers. In another aspect, pharmaceutical compositions of low-solubility drugs and amphiphilic, hydroxy-functional vinyl copolymers are disclosed.

The invention discloses an organic polysilazane / inorganic nano-material super-hydrophobic coating and a preparation method thereof. According to the preparation method, firstly, an organic polysilazane solution is prepared, a silane coupling agent containing hydrophobic units is used for carrying out hydrophobization on an inorganic nano-material, and dispersion liquid of the hydrophobic inorganic nano-material is prepared; then, an organic material or an inorganic material or a metal material serves as a base material, and an organic polysilazane and the hydrophobic inorganic nano-material alternatively deposit on the surface of the base material in sequence through a deposition method; finally, appropriate heat treatment is carried out on the surface which is subjected to multiple times of alternative deposition. The obtained coating shows good super-hydrophobic performance, the contact angles of water drops on the surface of the coating are larger than 150 degrees, the rolling angles are smaller than 10 degrees, and the coating has good mechanical and chemical stability and has wide application prospect in the field of waterproof clothes, exterior wall coating, oil-water separation, biomedicine and the like. According to the method, the preparation process is simple, and large hydrophobic coatings can be established on various base material surfaces.

Crosslinked polybenzoxazines obtained by crosslinking a monofunctional first benzoxazine monomer and a multifunctional second benzoxazine monomer with a crosslinkable compound, an electrolyte membrane including the same, a method of preparing the electrolyte membrane, a fuel cell including the electrolyte membrane having the crosslinked polybenzoxazines using the method. The crosslinked polybenzoxazines have strong acid trapping capability, improved mechanical properties, and excellent chemical stability as it does not melt in polyphosphoric acid. Even as the amount of impregnated proton carrier and the temperature are increased, mechanical and chemical stability is highly maintained, and thus the electrolyte membrane can be effectively used for fuel cells at a high temperature.