9209 results about "Pharmaceutical formulation" patented technology

A hand applicator of encapsulated liquids, such as cosmetic, hygienic, and pharmaceutical formulations or household chemicals, of different viscosity. When the user squeezes the applicator in her hand, the capsule inside it ruptures, possibly with a clap, and releases a liquid that after being collected by the drain passes through the perforated dissector to get evenly distributed in the absorber and then evenly applied on skin or other surfaces. Inert and impermeable capsules ensure stability of stored liquid formulations. Pressurized capsules are easily tactilely located and crashed. A capsule may be permanently or elastically fixed within the applicator. The applicator may include several capsules that may contain different liquids. A refillable applicator can be refilled with new capsules and used more than once. A transparent impermeable back side the applicator enhances hygiene and creates visibility of the capsule. An impervious glove-applicator for applying hazardous substances is disclosed.

Disclosed in certain embodiments is an oral dosage form comprising a therapeutically effective amount of an opioid analgesic, an opioid antagonist and one or more pharmaceutically acceptable excipients; the dosage form further including a gelling agent in an effective amount to impart a viscosity unsuitable for administration selected from the group consisting of parenteral and nasal administration to a solubilized mixture formed when the dosage form is crushed and mixed with from about 0.5 to about 10 ml of an aqueous liquid.

Disclosed in certain embodiments is an oral dosage form comprising a therapeutically effective amount of an opioid analgesic; an opioid antagonist; and a bittering agent in an effective amount to impart a bitter taste to an abuser upon administration of the dosage form after tampering.

Methods of using tetanus toxin to modulate or control neural functions or nonneural cellular activities at selected sites in animals, particularly in mammals, and more particularly in humans, are provided. Pharmaceutical formulations to modulate neural functions or non-neural cellular activities of an animal at selected sites in animals, particularly in mammals, and more particularly in humans are also provided. Uses of tetanus toxin in preparation of medicaments for methods of treating clinical disorders or symptoms of animals, particularly mammals and more particularly humans are also provided.