The invention relates to an anti-dandruff and antipruritic shampoo, and belongs to the technical field of household chemical engineering. The shampoo is prepared from a shampoo base and a Chinese herbal medicine extract, wherein the Chinese herbal medicine extract is prepared by mixing and extracting the following components in percentage by weight: 30-45% of hibiscus leaves, 20-30% of tea dregs; 10-15% of coptis chinensis, 10-15% of baical skullcap roots, 5-10% of white mulberry root-bark and 5-10% of impatiens balsamina. The shampoo provided by the invention contains the extract of the hibiscus leaves and the tea dregs, so that scalp and hair can be well cleaned and cared; the adopted coptis chinensis, baical skullcap roots, white mulberry root-bark and impatiens balsamina contain natural bacteria decontamination agents, so that fungi and bacteria on the head can be killed; the hibiscus leaves and white mulberry root-bark contain antiphlogistic ingredients, so that a symptom of scalp itching caused by bacteria and fungi can be relieved. The shampoo provided by the invention has efficacies of removing dandruff and itching, conditioning scalp, nourishing hair and the like.