Patents
Literature
Hiro is an intelligent assistant for R&D personnel, combined with Patent DNA, to facilitate innovative research.
Hiro

258 results about "Ethyl oleate" patented technology

Ethyl oleate is a fatty acid ester formed by the condensation of oleic acid and ethanol. It is a colorless to light yellow liquid. Ethyl oleate is produced by the body during ethanol intoxication. Ethyl oleate is used as a solvent for pharmaceutical drug preparations involving lipophilic substances such as steroids. It also finds use as a lubricant and a plasticizer. Louis Bouveault used ethyl oleate to demonstrate Bouveault–Blanc reduction, producing oleyl alcohol and ethanol, a method which was subsequently refined and published in Organic Syntheses.

Spontaneous emulsions containing cyclosporine

A pharmaceutical composition contains cyclosporine as the active ingredient. More specifically, the composition is an orally administered pharmaceutical formulation in the form of a spontaneous emulsion comprising cyclosporine, ethanol ethyl oleate and polyoxyethylene glycerol trioleate. A method for preparing an orally administered pharmaceutical composition involves first dissolving cyclosporine in ethanol. Polyoxyethylene glycerol trioleate and an oil component are then added, mixed and diluted in an aqueous media to form a spontaneous emulsion.
Owner:WOCKHARDT EU OPERATIONS SWISS

Preservative compositions

The present Invention relates to a preservative composition comprising:a mixture of two to ten of well characterized fragrance raw materials with a cosmetic function, of which at least two are selected from: allyl caproate, benzyl acetate, benzaldehyde, dihydrolsojasmonate, ethyl phenethylacetal, ethyl cinnamate, ethyl methyl phenyl glycidate, ethyl vanillin, 2-heptylcyclopentanone, geranyl acetate, heliotropine, cis-hex-3-en-1-ol, ethylene brassylate, nonalactone gamma, camphylcyclohexanol, undecalactone gamma, 2-t-butylcyclohexylacetate, pentyl salicylate, 2-phenylethanol and 2-phenylethyl acetate; and are contained in at least 20% by weight of said mixture;at least one preservative; and a sequestrant.
Owner:TAKASAGO INTERNATIONAL CORPORATION

Pharmaceutical compositions comprising fatty acid esters

ActiveUS20130267503A1Patient compliance is goodOptimizing pharmacological profileBiocideNervous disorderPsychosis drugEthyl ester
The present invention relates to an injectable, pharmaceutical composition comprising a C1-6 alkyl ester of a C10-20 fatty acid. In an embodiment, the fatty acid is ethyl oleate, isopropyl oleate, ethyl myristate, or isopropyl myristate. These compositions are useful for the delivery of anti-psychotic drugs.
Owner:ALKERMES PHARMA IRELAND LTD

Ivermectin nanoemulsion drug combination and preparation method thereof

The invention discloses an ivermectin nanoemulsion drug combination. Oil-in-water type nanoemulsion consisting of ethyl oleate, Tween-80, 1,2- propylene glycol and ivermectin is prepared from being diluted by double distilled water. The ivermectin nanoemulsion drug combination greatly improves the effect of ivermectin in resisting parazoon, enhances the dissolubility, safety and bioavailability and is a high-efficiency antiparasitic nano level medicinal preparation with convenient use and wide ways of administration.
Owner:LANZHOU INST OF ANIMAL SCI & VETERINARY PHARMA OF CAAS

Tanshinone IIA microemulsions and preparing method thereof

The invention discloses a tanshinone II A microemulsion preparation which has targeting and comparatively high entrapment efficiency and drug-loading rate, is not haemolytic and mainly applied to the treatment of tumor and a preparation method thereof. The invention comprises the following raw materials by weight percentage: 0.6-0.8 percent of tanshinone II A, 0.6-1.8 percent of phosphotide for injection, 2.5-3 percent of glycerin for injection, 1.5-3 percent of F68 for injection, 11-15 percent of ethyl oleate and water for injection. The preparation method of the invention is that first the tanshinone II A is dissolved in the ethyl oleate to prepare the oil phase mixture solution; next the phosphotide for injection, the glycerin for injection and the F68 for injection are dissolved in the water for injection which accounts for 60-70percent of the total water for injection to prepare the water phase solution; then the oil phase solution and the water phase solution are respectively preheated to 60-70DEG C and the oil phase solution is slowly dropped to the water phase solution when the water phase solution is blended; the mixed solution is then sheared for 1-2minutes in a high shearing dispersing emulsification machine and filtrated with a 0.8Mum filtration membrane when the solution is still hot and the rest water for injection is added to the filtrate; the liquid obtained from step d is homogenized by a high pressure emulsification machine and next filtrated with the 0.8 Mum filtration membrane; finally the filtrate obtained from step e is packaged, filled with nitrogen, sealed and disinfected.
Owner:THE SECOND HOSPITAL OF DALIAN MEDICAL UNIV

Icariin microemulsion and preparation method thereof

The invention relates to an icariin microemulsion which takes icariin as active ingredient; the icariin is dissolved in oil and then added with emulsifying agent, assistant emulsifier and water to prepare microemulsion with the micro emulsion grain diameter of 10-100nm, wherein, the oil can be one or more in oleic acid, ethyl oleate, isopropyl myristate or castor oil; the icariin microemulsion has the components with the mass percent: 0.66-6.02% of saturated solution of oil of icariin, 10-50% of emulsifying agent, 10-38% of assistant emulsifier and the balance water, Hank's balanced salt solution (HBSS), PBS buffer solution or normal saline. The icariin microemulsion can be kept clear, transparent, stable and uniform when being placed at room temperature for a year, thus good stability is verified evidently. The experiments of cells and animals prove that the icariin microemulsion can strengthen the icariin to penetrate cell layers, promote the medicine to be ingested and absorbed and enhance the healing effect of the medicine. The invention also discloses a preparation method of the icariin microemulsion.
Owner:贾晓斌

Method for preparing linoleic acid sustained-release algal inhibiting agent

A method for preparing a linoleic acid sustained-release algal inhibiting agent comprises the following steps that firstly, linoleic acid is dissolved through ethyl oleate, emulgator is added into the linoleic acid, and the emulsified linoleic acid is added into a solution of sodium alginate tech grade; secondly, the solution obtained in the first step is dropwise added into a glacial acetic acid solution containing chitosan and calcium chloride to form microspheres; thirdly, after the microspheres are cooled to the indoor temperature, a cross-linking agent is added into the cooled microspheres; fourthly, the process of suction filtration is carried out, and the microspheres to which the cross-linking agent is added are washed by petroleum ether and distilled water; fifthly, the linoleic acid sustained-release algal inhibiting agent is obtained after drying. Algal inhibition effective time is prolonged, the algal inhibition effect is improved, and cost is reduced. All adopted preparing materials are natural polymer materials which are non-toxic, good in biocompatibility and biodegradable, and the problems of secondary pollution caused by chemical algal removing and bio-concentration and biological amplification caused by chemical medicines can be effectively avoided.
Owner:HOHAI UNIV

Prepn process of iodized plant ethyl oleate

The present invention relates to preparation process of iodized vegetable oil ethyl ester. Iodized vegetable oil is first produced with vegetable oil and hydrogen iodide gas through addition reaction, and iodized vegetable oil and ethanol then produce ester exchange reaction under the action of alkali catalyst to produce iodized vegetable oil ethyl ester, with the hydrogen iodide gas being produced through reaction of iodine, red phosphorus and water. The present invention has facile cheap materials and high conversion rate of ester exchange reaction, and the product has low viscosity.
Owner:季珉

Abiraterone oral spray and use and preparation methods thereof

The invention relates to the technical field of pharmaceutical preparations and particularly relates to an abiraterone oral spray. The abiraterone oral spray comprises the following components in percent by weight: abiraterone acetate, an oil phase, a surfactant, a co-surfactant and the balance of water, wherein the oil phase is used as a carrier for prompting system micro-emulsification, and the oil phase is medium chain triglyceride, ethyl oleate or oleic acid; the surfactant is used for improving the performance of the abiraterone oral spray, expanding the range of application and realizing solubilization, and the surfactant is polyoxyethylene 40 hydrogenated castor oil or polyoxyethylene 35 castor oil; and the co-surfactant is used for reducing the surface tension of liquid and enhancing the emulsifying, moistening and blistering effects, and the co-surfactant is ethanol, n-butyl alcohol or propylene glycol. The spray has the advantages that the taking dose is reduced, so that the manufacturing cost is lowered; the formation of invalid metabolites is reduced, so that adverse reactions are effectively reduced; and the drug effect of the spray is longer than that of an oral drug.
Owner:HANGZHOU ANDE TECH CO LTD

Preparation method for metal oleate

The invention relates to a preparation method for metal oleate, belonging to the preparation method of metal organic compounds. The preparation method for the metal oleate comprises the following steps of: using an ion exchange method to prepare the metal oleate; adopting alkali or alkaline-earth metal oleate and metal inorganic compounds as reactants, and mixing the reactants in the solvent containing water phase and oil phase; heating, stirring and reacting for certain time to form a layered mixed solution; and carrying out evaporating separation treatment on the oil phase to obtain high-purity metal oleate. The preparation method provided by the invention can prepare high-purity metal oleate by optimizing the reaction processes and synthesis conditions, is used for preparing a high-performance mono-disperse inorganic nanometer material, and is a green process for metal ion recycling. Besides, the preparation method has the characteristics of low preparation cost, economical efficiency, environmental-friendliness, and easiness in industrialization.
Owner:NANJING TECH UNIV

Synthesis of iodized plant ethyl oleate for injection

The present invention is process of synthesizing iodized vegetable oil ethyl ester. Vegetable oil ethyl ester is first produced through the ester exchange reaction of vegetable oil and anhydrous ethanol under the action of alkali catalyst, and then addition reacted with hydrogen iodide gas to produce iodized vegetable oil ethyl ester, with the hydrogen iodide gas being produced through reaction of iodine, red phosphorus and water. The present invention has facile cheap materials, and the product has high stability, low viscosity, light color and other features.
Owner:季珉

Matrine type alkaloid microemulsion and preparation method thereof

The invention relates to matrine microemulsion and a preparation method thereof, which overcomes the defects of low solubility and low bioavailability of matrine and improves the stability of matrine microemulsion. The invention adopts microemulsion as a pharmaceutical carrier to prepare matrine O / W type microemulsion with liquid drop of 1 to 100nm particle size so as to improve the dispersity of enveloped medicaments, promote the percutaneous absorption of plant surface cuticle and strengthen the effect of eliminiting insect injury, thereby providing scientific basis for theory and application study. The invention also relates to a method of forming stable O / W emulsion by doping matrine into oil. The compound comprises matrine, oil phase, water and surfactant. In a preferred embodiment, the oil is tween 80, an emulgator is ethyl oleate, and an emulgator assistant is absolute ethyl alcohol. The medicament content of soluble water aqua of matrine type alkaloid microemulsion is improved,the medicament effect is strengthened, the cost is saved and the medicament is more effectively to be absorbed by crops by forming matrine type alkaloid O / W microemulsion.
Owner:SHENYANG PHARMA UNIVERSITY

Methods of obtaining epothilone D using crystallization and /or by the culture of cells in the presence of methyl oleate

InactiveUS6998256B2Useful in treatmentProduce epothilonesOrganic chemistryBacteriaMyxococcus xanthusMethyl oleate
Methods are provided for purification of epothilone D and epothilone D analogs from epothilone producing cells such as, for example, Sorangium cellulosum and Myxococcus xanthus (recombinant). Epothilone can be purified from fermentation broth, for example by using resins, chromatography, and crystallization. Epothilone D can be crystallized from a binary solvent system in which water is the forcing solvent.
Owner:KOSAN BIOSCI

Method for epoxidating methyl oleate

The invention discloses a method for epoxidating methyl oleate, which comprises the following steps of: adding the methyl oleate into a reactor, adding a catalyst and an organic solvent, heating the mixture to the required reaction temperature of 50 to 70 DEG C, keeping constant the temperature, adding dropwise hydrogen peroxide with the concentration of 30 weight percent according to the mass ratio of the hydrogen peroxide to the methyl oleate of 1-2:1 in a way of ensuring that the dropwise addition of the hydrogen peroxide is finished within 2 to 2.5 hours, and continuing to preserve the heat for 2 to 6 hours after the dropwise addition is finished, wherein the mass ratio of the organic solvent to the methyl oleate is 2.0-5.0:1, and the mass ratio of the catalyst to the methyl oleate is 5-25:1,000; standing the reacted mixed solution in an environment of 5 to 10 DEG C for 3 to 5 hours to slowly separate the catalyst out and filtering the mixed solution to remove the catalyst; and standing and demixing filtrate, and distilling an organic layer under reduced pressure to remove the organic solvent to obtain the product epoxy methyl oleate. The method has the advantages of easy post-treatment, no environmental pollution, and high percent conversion and selectivity.
Owner:CHINA RES INST OF DAILY CHEM IND

Rubber material for wind power generation cable sheath

The invention discloses a rubber material for a wind power generation cable sheath. The rubber material is prepared from the following raw materials in parts by weight: 50-70 parts of chloroprene rubber, 10-18 parts of butadiene rubber, 20-32 parts of natural rubber, 15-20 parts of organic modified montmorillonite, 1-1.5 parts of magnesium oxide, 0.8-1.3 parts of zinc oxide, 1.5-2.8 parts of dicumyl peroxide, 0.3-0.8 part of triallyl polyisocyanurate, 1-3 parts of diisobutyl adipate, 0.8-2.2 parts of ethyl oleate, 5-8 parts of hazelnut oil, 1.2-1.6 parts of stearic acid, 20-35 parts of carbon black, 10-15 parts of carbon black purple, 1.0-1.5 parts of N-cyclohexyl-2-benzothiazole sulfonamide, 0.5-1.6 parts of tetramethyl thiuram disulfide, 1.8-2.2 parts of N-isopropyl-N'-phenyl p-phenylenediamine and 0.4-0.8 part of N-phenyl-2-naphthylamine. The organic modified montmorillonite is prepared by the following steps: adding sodium-based montmorillonite into water, stirring and standing and taking supernate; and after heating the supernate, adding octadecyl trimethyl ammonium chloride, carrying out ultrasonic treatment for 60-80 minutes, and after stirring, filtering and washing. The rubber material for the wind power generation cable sheath, which is disclosed by the invention, has low-temperature resistance and high elasticity and the flame retardance is further improved.
Owner:ANHUI LAND GRP

Manufacture method of 1, 3-bi-oleic acid-2-palmitic acid triglyceride

The invention relates to a dairy product, in particular to a manufacture method of 1, 3-bi-oleic acid-2-palmitic acid triglyceride. The manufacture method mainly solves the technical problems that if normal hexane is used as a solvent in manufacture in the prior art, product quality is affect, the normal hexane is not suitable for infant products, and production capacity is reduced; and if monoglyceride is used alone to be in reaction with oleic acid so as to generate OPO, production procedures are increased, production cost is high and the like. According to the manufacture method of the 1, 3-bi-oleic acid-2-palmitic acid triglyceride, solid super acid is used as a catalyst, and glycerol and palmitic acid undergo esterification reaction so as to generate tri-palmitic acid glyceride. Immobilization positioning lipase is used as a catalyst, the manufactured tri-palmitic acid glyceride undergoes ester exchange with one of oleic acid, methyl oleate, and ethyl oleate, and the 1, 3-bi-oleic acid-2-palmitic acid triglyceride is manufactured.
Owner:HANGZHOU HENGNUO SCI & TECH

High epoxide number environment-friendly plasticizer production process

The invention discloses a high epoxide number environment-friendly plasticizer production process. The production process comprises the following steps of: adding cottonseed oil, methanol and sodium methoxide into an ester exchange reactor for reaction to obtain mixed fatty acid methyl ester; adding into a rectifying tower for separation, and performing epoxidation, neutralization, washing and dehydration on methyl oleate obtained from the tower bottom to obtain a high epoxide number environment-friendly plasticizer; and performing sulfonation reaction on palmitic acid methyl ester obtained from the tower top and sulfur trioxide, and ageing, esterifying, neutralizing and drying to obtain an environment-friendly surfactant MES. By the production process, the raw materials are readily available, the process is advanced, equipment is simple, the high epoxide number plasticizer can be prepared, and the byproduct, namely the palmitic acid methyl ester can be used for producing the environment-friendly surfactant.
Owner:扬州市双全塑胶材料厂

Gas chromatography method for qualitatively and quantitatively detecting soya fatty acid components

The invention relates to a gas chromatography method for qualitatively and quantitatively detecting soya fatty acid components. The gas chromatography method is characterized in that fatty acids in soya seeds are extracted by adopting methods of heating and methylating and detected by adopting a gas chromatography, and the actual content of the fatty acid components in the soya seeds can be accurately detected according to a standard curve and a regression equation of standard samples of five fatty acid methyl esters (methyl palmitate, methyl stearate, methyl oleate, methyl linoleate and methyl linolenate). The method is applicable to qualitative and quantitative analysis of the fatty acid components of the soya seeds, is simple and convenient to operate, easy to control and easy to popularize, can be used for detecting relative percentage content of the five fatty acid components and accurately calculating the absolute content of each fatty acid component in the soya seeds, and has an important meaning in soya fatty acid detecting and breeding.
Owner:INST OF CROP SCI CHINESE ACAD OF AGRI SCI

Chitosan-containing curcumin slow-release aggregate and preparation method thereof

ActiveCN106822044AStable liquid crystal structureReduce wasteAntibacterial agentsAntipyreticCrystallographyWater soluble
The invention discloses chitosan-containing curcumin slow-release aggregate and a preparation method thereof; the chitosan-containing curcumin slow-release aggregate comprises transparent immobile liquid crystal; the liquid crystal comprises a surfactant, ethyl oleate and water at a mass ratio of (34-56):(1-14):(38-57), wherein the surfactant is a mixture of tween-80 and water-soluble chitosan, and the mass ratio of the tween-80 to the water-soluble chitosan is (4-9):1; the liquid crystal is coated with curcumin; the curcumin has a concentration of 0.7-2.5 mg / g in the liquid crystal. The chitosan-containing curcumin slow-release aggregate has good structural stability, has improved curcumin slow-release effect and allows the curcumin to be present and released continuously and stably.
Owner:海生健康科技(青岛)有限公司

Method for preparing methyl oleate from vegetable oil under catalysis of silicon dioxide-supported heteropolyacid

The invention discloses a method for preparing methyl oleate from vegetable oil under catalysis of silicon dioxide-supported heteropolyacid, which belongs to the technical field of fine chemical synthesis. In the invention, silicon dioxide is used as a solid phase carrier to support phosphotungstic acid to catalyze the reaction of the vegetable oil and methanol, and soybean oil, palm oil, colleseed oil, peanut oil, cottonseed oil and other vegetable oil are used as raw materials to be reacted with methanol to form methyl oleate. Compared with the conventional method using strong acid, strong alkali and the like as a catalyst, the reaction can be performed under normal pressure, acid-resistance and alkali-resistance equipment are not needed, the reaction conditions are mild, waste water, waste liquid and waste gas pollutants are not emitted, the silicon dioxide-supported heteropolyacid catalyst can be recycled and reused, and the method meets energy-conservation and environment-protection requirements.
Owner:TIANJIN POLYTECHNIC UNIV

Method for synthesizing methyl oleate

The invention discloses a method for synthesizing methyl oleate. The method is characterized by comprising the following steps: carrying out an esterification reaction between oleic acid and methanol in the presence of an H2SO4 / SiO2 immobilized catalyst, filtering the reaction solution, and purifying the filtrate through column chromatography to obtain colorless transparent oily liquid methyl oleate, wherein the molar ratio of oleic acid to methanol is 1: (1.5-5); and the molar ratio of the catalyst to oleic acid is 1: (10-50). Compared with the prior art, the method has the advantages that the method is simple in process, convenient to operate, low in production cost, high in yield and mild in reaction conditions, the consumption of raw materials is further reduced, the yield can be improved to be over 90 percent, and the production cost is obviously reduced; and moreover, the catalyst is simple in after-treatment and slight in pollution and can be recycled, and the method is a methyl oleate synthesizing method which is environment-friendly, economic and high-efficiency and has a good application prospect.
Owner:EAST CHINA NORMAL UNIVERSITY

Weed killer containing moxa leaf extract and application thereof in saline-alkali soil sugarbeet planting

The invention provides a weed killer containing moxa leaf extract and application thereof in saline-alkali soil sugarbeet planting. The weed killer comprises the following raw material components in parts by weight: 5-9 parts of clopyralid, 6.4-7.8 parts of moxa leaf extract, 2.3-5.5 parts of phosethyl-al, 1.2-2.6 parts of sophocarpidine, 1-2 parts of ethyl oleate, 3-4 parts of camphor, 8-10 parts of adhesive and 19-22 parts of solid carrier; the adhesive is triphenylmethyl ethylphenol polyoxyethylene ether; and the solid carrier is tapioca flour. In the application of the weed killer in saline-alkali soil sugarbeet planting, the control effect of green bristlegrass is 99.5% to 100%, the control effect of Chenopodium glaucum is 98.8% to 99.6%, the control effect of Siberian cocklebur is 99.5% to 100%, the control effect of nightshade is 98.5% to 99.2%, and the control effect of wormwood is 97.4% to 98.6%.
Owner:WEIFANG YOURONG IND

Artesunate nanoemulsion drug composition and preparation method thereof

The invention discloses an Artesunate nanoemulsion drug that is an O / W (oil-in-water type) nanoemulsion system consisting of ethyl oleate, Tween-80, normal butanol, ultrapure water and Artesunate. The nanoemulsion drug effectively overcomes the first-pass effect of traditional tablets in liver, causes no sense of pain in injection and greatly improves the insecticidal and helminthic effect of original Artesunate. Meanwhile, the nanoemulsion system has high drug-loading rate, is stable when stored, has certain slow release function compared with merchant Artesunate injection, and further is convenient for administration, thus greatly improving the bioavailability. Besides, shown by acute toxicity tests and clinical drug effect tests on mice, the nanoemulsion has no obvious toxic or side effect and is a safe, reliable and high-efficiency nano level antiparasitic drug.
Owner:LANZHOU INST OF ANIMAL SCI & VETERINARY PHARMA OF CAAS

C18 series fatty acid and C20-C22 series fatty acid fine separation method

The invention discloses a C18 series fatty acid and C20-C22 series fatty acid fine separation method. The method includes: pretreating the raw material animal and vegetable oil by a ionic liquid to obtain high-yield and low-acid value biodiesel, i.e. a mixture of a variety of fatty acid methyl esters, with the process being simple, green and environment-friendly; then placing the obtained biodiesel in a pressured reduced rectification tower kettle, taking the ionic liquid as an extraction agent to conduct extraction pressured reduced rectification, and collecting methyl stearate, methyl oleate and methyl linoleate or eicosapentaenoic acid methyl ester and docosahexaenoic acid methyl ester with mass percentage purity of over 98% at the tower top. The method provided by the invention makes up the blank of the prior art, has a convenient operation process, provides the operation process for separation of long-chain fatty-acid methyl esters with a same carbon number, different double-bond numbers and poor heat sensitivity, and lays the foundation for fine separation of fatty acid methyl ester.
Owner:天津领碳能源环保科技有限责任公司

Manufacturing method for preparing methanol diesel fuel from industrial methanol

InactiveCN101935559AGood stability without delaminationNo corrosionLiquid carbonaceous fuelsTert butyl phenolAlkylphenol
The invention discloses a manufacturing method for preparing methanol diesel fuel from industrial methanol. The method comprises the following steps of: putting ethanolamine and naphthenic acid into the industrial methanol according to a certain proportion and mixing to obtain denatured methanol for later use; selecting alkylphenol ethoxylates, dimethyl carbonate, ethyl oleate and para-tert-butyl phenol according to a proportion, sequentially adding the alkylphenol ethoxylates, the dimethyl carbonate, the ethyl oleate and the para-tert-butyl phenol into a container and stirring for 20 to 30 minutes so as to obtain a methanol diesel fuel modifier for later use; and adding 75 percent diesel fuel mixed liquor into 20 percent denatured methanol, stirring fully and uniformly, adding 5 percent diesel fuel modifier and fully mixing so as to obtain finished methanol diesel fuel. A methanol diesel fuel product has the advantages of no delamination, high stability, no corrosion, no swelling, no emulsification, high explosive force, convenient use, readily available raw materials, low manufacturing cost and easy popularization.
Owner:唐山市隆泰科技有限公司

Doxycycline hydrochloride long-acting injection and preparation method

The invention relates to an application of sustained-release material sucrose acetate iso-butyrate used in in-situ gel preparations to preparation of an oil suspension injection for livestock, and in particular relates to a method used for preparing a doxycycline hydrochloride long-acting injection by combining sucrose acetate iso-butyrate and hydrogenated castor oil or aluminium stearate. A dispersion medium of the preparation is isopropyl myristate, benzyl benzoate, ethyl oleate or a mixture of more than one of isopropyl myristate, benzyl benzoate and ethyl oleate. The preparation has good sustained release effects, stable characters and good tissue compatibility, and is easy to prepare.
Owner:中农华威制药股份有限公司

Stable carbon deposit-removing gasoline additive

A stable carbon deposit-removing gasoline additive is prepared from the following raw materials in parts by weight: 8-14 parts of polyoxyethylene sorbitan monooleate, 3-9 parts of ethyl oleate, 5-10 parts of isopropanol, 4-9 parts of fatty alcohol polyoxyethylene ether, 4-10 parts of cyclohexane acid glycerol ester, 1-5 parts of oleic acid, 3-9 parts of vegetable oil, 1-6 parts of isobutanol, 2-6 parts of naphtha, 1-6 parts of Tween 80, 3-10 parts of trichloroethane, 6-10 parts of m-methyl benzoic acid, 1-5 parts of trichloroacetic acid, 3-5 parts of ethanol, 6-11 parts of a camphor extracting solution and 5-10 parts of glycerol monostearate. The stable carbon deposit-removing gasoline additive has the benefits as follows: the stable carbon deposit-removing gasoline additive can reduce emission and reduce environment pollution, has a very good cleaning and carbon-removing effect, and can protect an engine well.
Owner:QINGDAO KELIKE INFORMATION TECH

Sarah rhzomorph nano emulsion medicine composition and preparation method thereof

The invention discloses a method for preparing a Sarah rhzomorph nano emulsion medicine composition and a formula. The preparation is an O / W (oil-in-water type) nano emulsion system which consists of ethylis oleas, Tween-80, n-butyl alcohol, ultrapure water and Sarah rhzomorph; the nano emulsion system has high medicine loading quantity (more than 11 percent); the medicine can be diluted by injection water or normal saline according to any rate in accordance with the clinical practical requirements; and the medicine is stably placed, so that the bioavailability of the medicine is greatly improved, the high dosage of the traditional transdermal medicine is effectively overcome; the insecticidal insect repellent function on the Sarah rhzomorph is greatly improved; and the clinical dosage of the Sarah rhzomorph is reduced to an extreme limit. The content of 1 percent of the preparation auxiliary materials (ethylis oleas, Tween-80, n-butyl alcohol and the like) is reduced to 4.1 percent on year-on-year basis; the content of 1 millesimal of the preparation auxiliary materials is reduced to 4.1 millesimal; the external properties are the same as those of true solution; compared with the transdermal preparation, the clinical dosage of the Sarah rhzomorph is reduced from 6mg / kg to 0.2mg / kg, and the curative effect is same; and therefore, at the present of deficiency of raw material medicines, the Sarah rhzomorph nano emulsion medicine is successfully researched, so that the dosage quantity is reduced, the dosage cost of a livestock master is reduced, the damage of the medicines to environment and public hygiene is greatly reduced; and in addition, according to an acute toxicity test and clinical pharmacodynamic test on mice, the nano emulsion medicine is free of toxic and side effects, so that the nano-level anti-parasitic medicine is safe, reliable and effective.
Owner:LANZHOU INST OF ANIMAL SCI & VETERINARY PHARMA OF CAAS

Bonding agent for starch-based corrugated paper and preparation method thereof

The invention provides a bonding agent for starch-based corrugated paper and a preparation method thereof. The preparation method comprises the following steps: (1) preparing 8 to 12 percent sodium hydroxide and a 20 to 30 percent hydrogen peroxide solution, and performing ultrasonic oscillation to mix uniformly; (2) placing potato starch into a clean and dry reaction vessel, adding water, and stirring for 10 to 15 minutes at a speed of 80 to 160 revolution / minute until uniform mixing; (3) adding ferrous sulfate and the hydrogen peroxide solution, stirring for reacting for 10 to 20 minutes, adding the sodium hydroxide solution while stirring, and stirring and pasting until the shape of the solution does not change any more; (4) adding sodium borate and tributyl phosphate, and stirring continually for 20 to 30 minutes; (5) adding modified urea resin, ethylis oleas, ammonium oxide, modified konjac glucomannan, modified carrageenan and a preservative, and uniformly mixing to obtain the bonding agent. The bonding agent for the starch-based corrugated paper has very high viscosity and water resistance.
Owner:苏州纳贝通环境科技有限公司

Nanometer emulsion capable of promoting hair growth and preparation method of nanometer emulsion capable of promoting hair growth

The invention discloses nanometer emulsion capable of promoting hair growth and a preparation method of the nanometer emulsion capable of promoting hair growth. The nanometer emulsion capable of promoting hair growth comprises a hair growth promoting compound consisting of a pyrrolidinyl diaminopyrimidine oxide and baicalin, and a nanometer compound which consists of polyoxyethylene castor oil, lecithin, ethyl oleate, glutathione and ethanol and of which the particle diameter is 10-133m, wherein the mass ratio of the pyrrolidinyl diaminopyrimidine oxide to the baicalin is 5 to 2. The nanometercompound capable of promoting hair growth provided by the invention is an effective hair growth promoting substance consisting of the pyrrolidinyl diaminopyrimidine oxide and the baicalin, and can effectively promote hair growth; after the nanometer compound capable of promoting hair growth is prepared into the nanometer emulsion, the nanometer emulsion is low in irritants, good in stability andbetter in effects. The preparation technology is simple, and under low temperature and ordinary pressure, the nanometer compound having the effect of promoting hair growth can be prepared, is free from any toxic reagents, is green, efficient, short in cycle, high in yield and easy for popularization and mass production.
Owner:广州韩金靓化妆品有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products