1803 results about "Linoleic acid" patented technology

Oil produced from the seed of Brassica napus plant has an oleic acid content of 71.4-77.4% and a linoleic acid content of no more than 3%. The oil is useful in food and industrial applications. The oil has substantially improved oxidative stability relative to normal rapeseed oil, when both are identically treated with antioxidant.

The present invention relates to fungal Δ12 fatty acid desaturases that are able to catalyze the conversion of oleic acid to linoleic acid (LA; 18:2). Nucleic acid sequences encoding the desaturases, nucleic acid sequences which hybridize thereto, DNA constructs comprising the desaturase genes, and recombinant host microorganisms expressing increased levels of the desaturases are described. Methods of increasing production of specific ω-3 and ω-6 fatty acids by over-expression of the Δ12 fatty acid desaturases are also described herein.

This invention relates to corn (Zea mays L.) seed and grain having a significantly higher oleic acid content than conventional corn by virtue of heritable genes for increased oil and oleic acid content and / or lowered levels of linoleic acid. The present invention also relates to the production of high oil, high oleic grain, its oil, its progeny and its use.

Disclosed herein is an aqueous emulsion. The lipid phase of the emulsion includes a blend of a therapeutically effective concentration of a lipophile, a concentration of Vitamin E TPGS, and a concentration of linoleic acid. The presence of linoleic acid increases the solubilizing affect of Vitamin E TPGS on the lipophile and thus reduces the amount of Vitamin E TPGS that would otherwise be required in the aqueous emulsion.

The present invention relates to a Δ12 fatty acid desaturase able to catalyze the conversion of oleic acid to linoleic acid (LA; 18:2). Nucleic acid sequences encoding the desaturase, nucleic acid sequences that hybridize thereto, DNA constructs comprising the desaturase gene, and recombinant host microorganisms expressing increased levels of the desaturase are described. Methods of increasing production of specific ω-3 and / or ω-6 fatty acids are described by overexpression of the Δ12 fatty acid desaturase or by disruption of the native gene.

Serum-free media for growth and proliferation of chondrocytes and mesenchymal stem cells in culture are provided. A serum-free medium for growth of chondrocytes includes a serum-free composition comprising FGF-2, linoleic acid, ascorbic acid, B-mercaptoethanol, transferrin and dexamethasone. Further, the composition comprises EGF, PDGFbb, insulin and albumin. A method for growing chondrocytes in a serum free medium comprising the compostion is also provided. Also provided for mesenchymal stem cell growth, is a serum-free medium which includes a composition comprising FGF-2, LIF, SCF, pantotenate, biotin and selenium and method, therefore.

A food composition in which omega-3 fatty acids are stabilized against oxidation is disclosed. The food composition contains about 4 to about 100 weight percent of the composition in which triglycerides containing omega-3 fatty acids (and other fatty acids) are stabilized against oxidation in the absence of encapsulation. The fatty acid portion of the oil in the completed food composition includes less than about 10 percent by weight linoleic acid, at least 75 percent by weight of monounsaturated plus saturated fatty acids, and at least 3 percent by weight omega-3 fatty acids. The food composition can also contain comminuted peanuts, e.g., peanut butter, in which case the composition is also stabilized against photo-oxidation and the fatty acid portion of the oil portion of the food can contain less than about 15 percent by weight linoleic acid and at least 1 percent by weight omega-3 fatty acids. Methods of protecting a food composition from oxidation and photodegradation are also disclosed.

The invention discloses a slowly-released compound acidifier for poultry and livestock feed, a preparation method thereof and feed containing the same. The compound acidifier comprises the following compositions in part by weight: 30 to 80 parts of complex organic acid, 15 to 50 parts of supplementary materials and 5 to 20 parts of coating agents. The complex organic acid is citric acid, fumaric acid, malic acid, lactic acid, linoleic acid, crataegolic acid, ursolic acid, chlorogenic acid, glycyrrhizic acid and oleanolic acid, and the supplementary materials are silicon dioxide, hydroxypropyl methylcellulose and ethyl cellulose. The acidifier is scientifically proportioned, has strong efficiency and is long-acting and slow-releasing, nutrients in the feed are free from being damaged, the acidifier has good fluidity and is easy to be uniformly mixed with the feed, the digestive absorption of nutrients can be promoted, the conversion rate of the feed can be improved, the productivity of poultry and livestock can be improved, the time for domestic animals for sale can be effectively shortened, the health of gastrointestinal mucosa of the animals can be protected, the immunologic function of the animals can be strengthened, and diseases can be prevented.

Fat compositions and infant formulas containing oleic acid in an amount of at least about 50% by weight of total fatty acids, lauric acid in an amount of at least about 10% by weight, palmitic acid in an amount of not more than about 10% by weight and, in certain embodiments, linoleic acid in an amount of not more than about 16% by weight. The fat compositions can be prepared to contain one or more oleic acid oils in a total amount of at least about 50% by weight, one or more linoleic acid oils in a total amount of not more than about 18% by weight and, in certain embodiments, one or more lauric acid oils in an amount of at least about 20% by weight. Also disclosed are methods of making the fat compositions and infant formulas and methods for providing a fat component to infant diets.

Refrigeration-shelf-stable ready-to-feed and concentrated infant formulas prepared through an ultra-pasteurization and / or pasteurization process, comprise per five fluid ounces from about 1.8 to about 6.3 grams of protein; from about 3.3 to about 15.9 grams of fat; from about 300 mg to about 3000 mg of linoleic acid; from about 250 to about 900 IU of Vitamin A; from about 40 to about 180 IU of Vitamin D; from about 0.7 to about 9 IU of Vitamin E; from about 4 to about 24 mcg of Vitamin K; from about 40 to about 300 mcg of Thiamine (Vitamin B1); from about 60 to about 450 mcg of Riboflavin (Vitamin B2); from about 35 to about 180 mcg of Vitamin B6; from about 0.15 to about 0.9 mcg of Vitamin B12; from about 250 to about 3150 mcg of Niacin; from about 4 to about 48 mcg of Folic Acid (Folacin); from about 300 to about 1500 mcg of Pantothenic Acid; from about 1.5 to about 13.2 mcg of Biotin; from about 8 to about 36 mg of Vitamin C (Ascorbic Acid); from about 7 to about 48 mg of Choline; from about 4 to about 18 mg of Inositol; from about 60 to about 234 mg of Calcium; from about 30 to about 159 mg of Phosphorus; from about 6 to about 24 mg of Magnesium; from about 0.15 to about 5.4 mg of Iron; from about 0.5 to about 3 mg of Zinc; from about 5 to about 45 mcg of Manganese; from about 60 to about 270 mcg of Copper; from about 5 to about 75 mcg of Iodine; from about 20 to about 81 mg of Sodium; from about 80 to about 324 mg of Potassium; and from about 55 to about 195 mg of Chloride; wherein the total caloric content is from about 80 kilocalories to about 300 kilocalories per five fluid ounces.

A non-lauric, non-trans, non-temper (Non-LTT) fat composition comprising a fraction obtained from a randomised triglyceride mixture in which min. 90% by weight of the constituent fatty acids are: palmitic (C16:0), stearic (C18:0), arachidic (C20:0) behenic (C22:0), oleic (C18:1) and linoleic (C18:2) acid and the total content of arachidic and behenic acid is 3-40% by weight and the total content of palmitic and stearic acids is 25-60% by weight, said fraction having the following physical and chemical properties: (1) slip melting point measured according to AOCS Cc 3-25: below 36° C. and solid fat content (SFC) measured according to IUPAC 2.150 mod. (stabilised at 20° C. for 24 h): above 25% by weight at 20° C.; (2) total content of saturated fatty acids measured according to IUPAC 2.301 and 2.304: 40-75% by weight, preferably 45-70% by weight; (3) total content of arachidic and behenic acids: 3-40% by weight, preferably 5-35% by weight, and total content of palmitic and stearic acids: 25-60% by weight, preferably 25-50% by weight, both measured according to IUPAC 2.301 and 2.304; (4) total content of triglycerides having triglyceride composition (TGC) of C56-C60 measured by number of total carbon atoms of constituent fatty acids according to IUPAC 2.323: min. 9% by weight, preferably min. 15% by weight; (5) total content of S2U-type triglycerides: min. 25% by weight, preferably min. 35% by weight, where S=saturated fatty acids and U=unsaturated fatty acids.

Sterile nanoemulsions are prepared containing oily droplets of a diameter of less than 100 nm in an aqueous phase. The oily droplets contain a lipophilic substance, and have on their surface an amphoteric emulsifier in an amount of preferably 0.65 to 0.75 parts by weight amphoteric emulsifier for one part by weight of oily component forming the droplets. The oily component of the droplets is preferably a triglyceride containing oleic acid and / or linoleic acid. The nanoemulsions are used for delivering into cells the lipophilic substance contained by the oily droplets. This delivery can be used to biotransform the lipophilic substance, promote cell differentiation, growth or biosynthesis of a desired substance, or to test for toxicity of the lipophilic substance.

The present patent relates to a method for producing flours from grain myceliated with macroscopic fungi (mushrooms). These flours can be used to prepare food for human consumption, such as bread and biscuits, and for animal consumption, such as fodder. Active principles (ergosterol, beta glucan, linoleic and oleic acids, lectins), enzymes, proteins, amino acids, vitamins, mineral salts, inter alia, can also be extracted from these flours for use in the chemical, foodstuff and cosmetic industries, for producing phytotherapeutic agents, pharmaceuticals, textiles, paper products, pharmaceuticals and fodder for animals.

A nutritional fat or oil-based composition for increasing HDL cholesterol, decreasing LDL cholesterol and decreasing the LDL / HDL cholesterol ratio in human plasma is described. The composition typically includes at least 1% by weight myristic acid esterified at the sn-2 position in triglyceride molecules, includes between 10% and 40% by weight linoleic acid, and further includes between 30% and 65% by weight oleic acid and between 15% and 40% by weight total saturated fatty acids. The ratio of sn-2 myristic acid to sn-2 palmitic acid is typically greater than 1:1 and the sum of weight percentages for saturated, monounsaturated and polyunsaturated fatty acids equals 100%. In desirable cases, the composition is substantially cholesterol-free.

The nutritive layer feed is produced with 17 kinds of material, including corn, soybean dreg, shell powder, beer residue, sea weed, etc. The feed has high content of linoleic acid and the egg has obvious preventing and treating effect on iodine deficiency goiter, hyperthyroidosis, etc. It has high content of vitamin E, can stabilize lipoid in egg to inhibit the formation and diffusion of various kinds of cancer cell, and to possess the functions of inhibiting atherosclerosis, improving cardiac and cerebral vascular diseases, etc.

Pheromone compositions based on a combination of squalene, linoleic acid and 1-docosanol are described. The compositions are useful for behavior modification in mammals that exhibit undesirable or harmful stress-related behaviors.

A composition comprising a mixture of fatty acids such as oleic, palmitic and linoleic acids and derivatives thereof which are used for enhancing weight gain in a mammal. Methods to enhance weight gain using the fatty acid compositions are also described.

A method of inhibiting skin darkening whilst inhibiting perspiration in the underarm which comprises incorporating into a antiperspirant composition comprising an astringent salt comprising an aluminium and / or zirconium salt, a triglyceride oil and optionally an active acid comprising an aliphatic dicarboxylic acid, especially C6-C12 such as azelaic acid, an unsaturated C18 aliphatic carboxylic acid such as a linoleic acid or an hydroxybenzoic acid such as salicylic acid, at a ratio to said astringent salts, x:y, of 1:<4 in which x represents the weight concentration of said triglyceride oil plus 4 times the weight concentration of active carboxylic acid and y represents the weight concentration of said astringent salts. The composition can additionally comprise glycerol and / or a chelating agent for a transition metal.

The invention is directed to a food composition in an aqueous or instant powder form that contains at least one food ingredient, a monoglyceride enriched with unsaturated compounds, and water. The monoglyceride is preferably a monoglycerol monoester that has up to about 90% of C18 monoolein with one unsaturation, with the remainder being a C18 monolinolein with two unsaturations and / or a saturated monoglycerol monoester; a monoglycerol monoester that has up to about 90% of monolinolein C18 with two unsaturations, with the remainder being a monoolein C18 with one unsaturation and / or a saturated monoglycerol monoester; or a mixture of a saturated or unsaturated di- or polyglycerol monoester and a di- or polyglycerol di ester or polyester or another food emulsifier. The composition exhibits in an aqueous phase a mesomorphic structure such as a cubic, lamellar, or hexagonal structure substantially encapsulating or combining the food ingredient.

The present invention relates to in vitro cultured skin substitutes, and in particular to in vitro cultured skin substitutes that have improved barrier function. In some embodiments, improved barrier function is a result of improved culture conditions, while in other embodiments, improved barrier function results from genetic modification of keratinocytes. Improved culture conditions to improve barrier function include organotypic culture in the presence of linoleic acid and / or linoleic acid at about 75% humidity. Suitable genetic modifications for improving barrier function includes transfection with a DNA construct capable of expressing GKLF.

The invention discloses a composition containing a haematococcus extract and a collagen peptide. The composition is prepared from the following components in part by weight: 1 to 20 parts of haematococcus pluvialis extract, 1 to 10 parts of collagen peptide and 1 to 90 parts of safflower seed oil. The invention also discloses a preparation method for the composition. Natural astaxanthin in the haematococcus pluvialis extract has the ultrahigh oxidation resistance, ensures the normal metabolism of skin, inhibits the generation of melanin and enhances the effect of collagen; the absorption rate of the collagen peptide is between 95 and 100 percent; the collagen peptide can improve the metabolism of skin cells effectively, and can be utilized by the skin cells more easily, so that the activity of the collagen in the skin is enhanced, and the aims of preserving moisture, resisting wrinkles and nourishing the skin are fulfilled; and due to the addition of the safflower seed oil, the composition contains linoleic acid with high content and vitamin E and can prevent the oxidative deterioration of the astaxanthin, an antioxidant is not needed to be added, and the quality guarantee period can be prolonged by one time.

The invention relates to a feed and method for raising black pigs. The feed is prepared from 55-65% of corn meal, 10-20% of bean pulp, 5-15% of wheat bran, 2-6% of fish meal, 0.1-0.5% of salt and 5-10% of auxiliary materials by weight, wherein the auxiliary materials include fructus cannabis, almonds, fructus perillae and pumpkin seeds and also include schisandra chinensis, acanthopanax, pine leaves, horsetail, purslane and peony. The method comprises the following steps of: keeping the concentration of anions in the raising environment not to be less than 1000-1500 per cubic centimeter; selecting black pigs or binary or ternary hybrid pigs of the black pigs and boars; ensuring the culture cycle to be 9-16 months; and beginning feeding the feed every other day 40-45 days before marketing until marketing. The feed and the method have the following advantages that: the pigs cultured by the method have pure fragrant and tender meat and the meat is fat but not greasy and lean but not bonyand is rich in omega-3 unsaturated fatty acid and omega-6 linoleic acid.

The invention discloses a human adipose-derived stem cell serum-free basic medium. The medium uses a serum substitute, and is composed of a high glucose type DMEM basic medium, human serum albumin, transferrin, taurine, reduced glutathione, ceruloplasmin, L-ascorbic acid-2-sulfate, alpha-tocopherol succinate, linoleic acid, alpha-ketoglutarate and selenium. The serum-free basic medium can exempt potential threats caused by animal serum in conventional serum-containing mediums to human health, and the adipose-derived stem cells cultured by the medium is more suitable for clinical application.

The invention discloses health-maintaining vigor-curing paste and relates to a health care product. The health-maintaining vigor-curing paste comprises the following raw materials in parts by weight: 1-5 parts of donkey-hide gelatin, 2-12 parts of black sesame, 2-10 parts of denucleated dried red date, 2-10 parts of walnut kernel, 2-10 parts of almond, 1-6 parts of pine kernel, 2-8 parts of hazelnut kernel, 1-5 parts of medlar, 1-5 parts of rose, 1-5 parts of longan pulp, 0.5-4 parts of Indian buead, 1-5 parts of gordon euryale seed, 0.5-3 parts of semen coicis, 1-5 parts of fruit leather, 1-5 parts of crystal sugar and 4-20 parts of dried yellow rice. The donkey-hide gelatin, walnut, almond, pine, red date, Indian buead, gordon euryale seed, semen coicis and the like are taken as main components, and the health-maintaining vigor-curing paste contains rich glutin, linoleic acid, proteins, calcium, phosphorus, iron, carotene, vitamins, phospholipid, tannin and other nutrient substances and has the effects of relieving spleen and stomach burden, nourishing yin and supplementing blood, maintaining health and improving fitness, nourishing blood and moistening skin and tonifying kidney and soothing nerves.

The invention discloses a human adipose-derived stem cell serum-free basic medium. The medium uses a serum substitute, and is composed of a high glucose type DMEM basic medium, human serum albumin, transferrin, taurine, reduced glutathione, ceruloplasmin, L-ascorbic acid-2-sulfate, alpha-tocopherol succinate, linoleic acid, alpha-ketoglutarate and selenium. The serum-free basic medium can exempt potential threats caused by animal serum in conventional serum-containing mediums to human health, and the adipose-derived stem cells cultured by the medium is more suitable for clinical application.

The present invention relates to fungal Δ12 fatty acid desaturases that are able to catalyze the conversion of oleic acid to linoleic acid (LA; 18:2). Nucleic acid sequences encoding the desaturases, nucleic acid sequences which hybridize thereto, DNA constructs comprising the desaturase genes, and recombinant host microorganisms expressing increased levels of the desaturases are described. Methods of increasing production of specific ω-3 and ω-6 fatty acids by over-expression of the Δ12 fatty acid desaturases are also described herein.

Nitro oleic acid and related metabolites are agonists of PPAR-γ. Surprisingly, nitro oleic acid is a more potent agonist of PPAR-γ, relative to nitro linoleic acid. Thus, nitro oleic acid and its metabolites, as well as their pharmaceutically acceptable salts and prodrug forms, are candidate therapeutics for the treatment of type-2 diabetes, which results from insulin resistance accompanying the improper functioning of PPAR-γ.

The invention relates to a dimer acid-organic amine copolymer which comprises a structural unit from dimer acid, a structural unit from alkylamine and a structural unit from aromatic amine, wherein the dimer acid is an oleic acid-linoleic acid dimer; the alkylamine is one or more of C10-C20 alkyl primary amines, and the aromatic amine is aniline and one or more of anilines of which the benzene ring is subjected to single-point substitution or multipoint substitution by C1-C3 alkyl. The invention also relates to a preparation method of the dimer acid-organic amine copolymer, application of the dimer acid-organic amine copolymer as a shear strength improving agent, a water-in-oil emulsified drilling fluid shear strength improving agent, and a drilling fluid containing the shear strength improving agent. The shear strength improving agent provided by the invention can obviously enhance the dynamic shear force, dynamic plastic ratio and static shear force of the water-in-oil emulsified drilling fluid under the condition of lower consumption, and can be used in the water-in-oil emulsified drilling fluid which contains or does not contain organic soil.

The invention discloses a skin barrier repairing preparation. The preparation is prepared from the following components: deionized water, sucrose stearate, phytosteryl isostearate, vitamin E, glycerinum, butylene glycol, 1,2-pentylene glycol, octyldodecanol, polydimethylsiloxane, hydrogenated polyisobutene, oleic acid, linoleic acid, ceramide 2, ceramide 3, ceramide 6II, sodium hyaluronate, xanthan gum, disodium EDTA, acrylates C10-30 alkyl acrylate crosslinked polymer, allantoin and sorbitan caprylate. The invention further provides a method for preparing the skin barrier repairing preparation. According to the preparation method, the problem of dissolving compound ceramide can be solved, the impact of ceramide crystallization on stability under a low-temperature condition can be reduced, the stability of the preparation can be improved, and other skin repairing components can be added and compounded with the compound ceramide. The skin barrier repairing preparation has an excellent product formula stability and a multiple repairing effect on the skin barrier.

The invention discloses a Raman-spectrum-based method for detecting the content of oleic acid, linoleic acid and saturated fatty acid in edible vegetable oil. The method comprises the following steps of: detecting and pre-treating a Raman spectrum of edible vegetable oil with known content of oleic acid, linoleic acid and saturated fatty acid; presetting a characteristic peak set, and performing affinity modeling on the Raman spectrum strength corresponding to the edible vegetable oil to be detected and the known content of oleic acid, linoleic acid and saturated fatty acid, thus obtaining the Raman spectrum of the edible vegetable oil to be detected; and pre-treating the Raman spectrum, extracting the Raman spectrum strength corresponding to the characteristic peak set, and substituting the Raman spectrum strength in a prediction module to obtain the content of the oleic acid, linoleic acid or saturated fatty acid in the edible vegetable oil to be detected. The method disclosed by the invention is simple in operation, high in detecting speed and capable of simultaneously predicting the content of the three fatty acids according to the prediction module; and compared with a real result detected by a gas chromatographic method (GC), the prediction result of the method provided by the invention is higher in precision.