9348results about "Raman scattering" patented technology

An organic or organoelement, linear or branched, monomeric or polymeric composition of matter having a Raman-active component in the form of particles. The particles having a maximum dimension of 50 mum. The Raman-active compound is applied to a substrate. When the Raman-active compound is exposed to a laser light wavelength which is batochromically well beyond a spectral region of maximum absorbance of said Raman-active compound, Raman scattering can be detected.

A color translating UV microscope for research and clinical applications involving imaging of living or dynamic samples in real time and providing several novel techniques for image creation, optical sectioning, dynamic motion tracking and contrast enhancement comprises a light source emitting UV light, and visible and IR light if desired. This light is directed to the condenser via a means of selecting monochromatic, bandpass, shortpass, longpass or notch limited light. The condenser can be a brightfield, darkfield, phase contrast or DIC. The slide is mounted in a stage capable of high speed movements in the X, Y and Z dimensions. The microscope uses broadband, narrowband or monochromat optimized objectives to direct the image of the sample to an image intensifier or UV sensitive video system. When an image intensifier is used it is either followed by a video camera, or in the simple version, by a synchronized set of filters which translate the image to a color image and deliver it to an eyepiece for viewing by the microscopist. Between the objective and the image intensifier there can be a selection of static or dynamic switchable filters. The video camera, if used, produces an image which is digitized by an image capture board in a computer. The image is then reassembled by an overlay process called color translation and the computer uses a combination of feedback from the information in the image and operator control to perform various tasks such as optical sectioning and three dimensional reconstruction, coordination of the monochromater while collecting multiple images sets called image planes, tracking dynamic sample elements in three space, control of the environment of the slide including electric, magnetic, acoustic, temperature, pressure and light levels, color filters and optics, control for microscope mode switching between transmitted, reflected, fluorescent, Raman, scanning, confocal, area limited, autofluorescent, acousto-optical and other modes.

Methods and system for noninvasive determination of tissue analytes utilize tissue properties as reflected in key features of an analytical signal to improve measurement accuracy and precision. Physiological conditions such as changes in water distribution among tissue compartments lead to complex alterations in the measured analytical signal of skin, leading to a biased noninvasive analyte measurement. Changes in the tissue properties are detected by identifying key features in the analytical signal responsive to physiological variations. Conditions not conducive to the noninvasive measurement are detected. Noninvasive measurements that are biased by physiological changes in tissue are compensated. In an alternate embodiment, the analyte is measured indirectly based on natural physiological response of tissue to changes in analyte concentration. A system capable of such measurements is provided.

An organic or organoelement, linear or branched, monomeric or polymeric composition of matter having a Raman-active component in the form of particles. The particles having a maximum dimension of 50 mum. The Raman-active compound is applied to a substrate. When the Raman-active compound is exposed to a laser light wavelength which is batochromically well beyond a spectral region of maximum absorbance of said Raman-active compound, Raman scattering can be detected.

An apparatus and method are provided to verify the composition of a medical fluid in a fluid infusion channel by comparison with clinician-entered input. Light is transmitted through the channel and detected by a sensor that generates signals representative of the spectral data of the light detected. A processor compares the spectral data of the light detected to the spectral data associated with the expected contents of the channel to verify that the correct fluid is being infused.