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88 results about "Creatinine" patented technology

Creatinine (/kriˈætɪnɪn/ or /kriˈætɪniːn/; from Greek: κρέας, romanized: kreas, lit. 'flesh') is a breakdown product of creatine phosphate in muscle, and is usually produced at a fairly constant rate by the body (depending on muscle mass).

Cosmetic or dermatological preparation with a content of creatine, creatinine or derivatives thereof in combination with soybean germ extract

The invention is a cosmetic or dermatological preparation with a content of an active agent combination comprising (a) at least one creatinine compound selected from the group consisting of creatinine and derivatives of creatinine; (b) at least one creatine compound selected from the group consisting of creatine and derivatives of creatine; and (c) at least one soybean compound selected from the group consisting of soybean germ extracts and ingredients which can be isolated from soybean germ. The present invention also includes methods for stimulating collagen synthesis of the skin, for restructuring or rejuvenation of the skin, and for inspiring the body or senses comprising applying the preparation to the skin.
Owner:BEIERSDORF AG

Composition for eliminating interference of calcium dobesilate medicine on creatininase-method detection

ActiveCN108627654ASolve the problem of serious negative interferenceDisease diagnosisBiological testingHigh concentrationCreatininase
The invention relates to a composition for eliminating the interference of a calcium dobesilate medicine on creatininase-method detection. The composition comprises an R1 reagent, an R2 reagent and ahigh molecular oxidant, wherein the high molecular oxidant is one or more of high molecular peroxy acid, high molecular selenium oxide, high molecular sulfur chloride ether, N-substituted imide, water-soluble tetrazole and a Dess-Martin oxidant. The high molecular oxidant in the composition disclosed by the invention can react with the calcium dobesilate in a sample to be detected, the calcium dobesilate loses the effect of interfering enzyme-method creatinine detection and the accuracy of sarcosine-oxidase-method detection is improved, so that the problem of serious negative interference, caused by high-concentration calcium dobesilate in blood of a patient, on an enzyme-method creatinine project detection result when the patient orally takes the calcium dobesilate medicine is solved.
Owner:WUHAN HANHAI NEW ENZYMES BIOLOGICAL TECH CO LTD

Storage tolerance cell cryopreservation liquid

The invention discloses a storage tolerance cell cryopreservation liquid which comprises propylene glycol, dextran, potassium chloride, magnesium chloride, disodium hydrogen phosphate, monopotassium phosphate, sodium chloride, vitamin C, cholesterol, sodium bicarbonate, albumin, glucose, creatinine, chloramphenicol, streptomycin, glycerinum, sodium carboxymethylcellulose and sterile injection water. The components of the storage tolerance cell cryopreservation liquid disclosed by the invention are coordinated with one another and act with one another, so that the cryopreservation liquid disclosed by the invention can be easily preserved and has a relatively long shelf life, that is, the shelf life is as long as 3 months or grater, the operation is simple, the cryopreservation liquid does not need to be prepared temporarily on site, the time and the labor are saved, the cryopreservation liquid can be preserved at low temperature directly, no complex cryopreservation procedure is needed, the cell cryopreservation time is greatly shortened, the cryopreservation efficiency is improved, and the cryopreservation liquid is stable and reliable in preservation effect, convenient to transport, convenient to use, simple and easily available in raw material and worthy of market popularization and application.
Owner:重庆斯德姆生物技术有限公司

Process method for catalytic synthesis of poly lactic acid-glycolic acid by using bionic organic guanidinium

The invention relates to a new method for synthesis of a medical biodegradable material poly lactic acid-glycolic acid by copolycondensation of lactic acid and glycolic acid through a catalysis effect of a bionic creatinine hydrochloride creatininium chloride (creatininium hydrochloride). According to the method, the bionic creatininium chloride is adopted as a catalyst, the industrial-grade lactic acid (LA, 85% aqueous solution) and the glycolic acid (GA, 95%) are adopted as monomers, and bulk solvent-free two-stage copolycondensation is performed to obtain the medical degradable poly lactic acid-glycolic acid with characteristics of high biological safety, no toxicity and no metal. According to the present invention, the method of the present invention has characteristics of green catalyst and solvent-free bulk polymerization; the catalyst creatininium chloride has high biocompatibility and high biological safety, and does not have cell toxicity; the synthesized poly lactic acid-glycolic acid does not contain any metals and other toxic residues, and is applicable for medical and medicinal materials; the process is simple and easy to operate, the raw material cost is low, the operation is simple, and the method is applicable for the industrial implementation.
Owner:NANJING UNIV

Nested PCR (polymerase chain reaction) kit for detecting chicken-manure pollution in water body and detection method thereof

The invention discloses a nested PCR (polymerase chain reaction) kit for detecting chicken-manure pollution in a water body and a detection method thereof, and belongs to the field of the detection of pollution in water bodies. The nested PCR kit for detecting the chicken-manure pollution in the water body comprises two pairs of nested PCR primers, dNTP (deoxyribonucleoside triphosphate), a PCR buffer, a Taq polymerase, a Mg<2+> solution and ddH2O (double distilled water). Two rounds of PCR amplification are used by a nested PCR method. The detection method comprises the following steps of extracting a DNA (deoxyribonucleic acid) in a water sample, and carrying out a first round of PCR amplification by using the DNA in the water sample as a template, wherein the primers are an SCF (stem cell factor) and SCR (serum creatinine); after a reaction is terminated, carrying out a second round of PCR amplification by using a product of the first round of PCR amplification as a template, wherein the primers are an NCF (neutrophil chemotactic factor) and NCR (nitrile chloroprene rubber), and after the second round of PCR amplification is terminated, detecting the existence of a 403bp strip, which shows that the water body is subjected to the chicken-manure pollution, through agarose gel electrophoresis. According to the method, the detection sensitivity is greatly increased through the nested PCR amplification; a little chicken-manure pollution which exists in water can be detected; moreover, the method has a favorable specificity, and can be directly applied to the detection and the preventive treatment work of fecal pollution in the water body.
Owner:NANJING UNIV

Methods for determining total body skeletal muscle mass

The present invention is based on the finding that enrichment of isotope-labeled creatinine in a urine sample following oral administration of a single defined dose of isotope-labeled can be used to calculate total-body creatine pool size and total body skeletal muscle mass in a subject. The invention further encompasses methods for detecting creatinine and isotope-labeled creatinine in a single sample. The methods of the invention find use, inter alia, in diagnosing disorders related to skeletal muscle mass, and in screening potential therapeutic agents to determine their effects on muscle mass.
Owner:RGT UNIV OF CALIFORNIA +1

Method of treating keratinic fibers with creatine, creatinine and/or their salts to strengthen, restructure, harden and stabilize them

The method of hardening, fortifying, restructuring, repairing, increasing volume or stabilizing keratinic fibers, especially human hair, includes providing a keratinic fiber treatment composition containing from 0.05 to 1.0 percent by weight of creatine, a salt of creatine, creatinine and / or a salt of creatinine, bringing the keratinic fiber treatment composition into contact with the keratinic fibers and allowing the keratinic fiber treatment composition to remain in contact with the keratinic fibers for a certain time interval.
Owner:WELLA GMBH

Medicament for treating viral hepatitis

The invention discloses a medicament for treating viral hepatitis. The medicament is prepared from the raw materials: 10 to 15 parts of isatis root, 8 to 12 parts of folium isatidis, 6 to 10 parts of honeysuckle stem, 2 to 6 parts of ginseng, 6 to 10 parts of root of red-rooted salvia, 8 to 12 parts of astragalus root, 2 to 3 parts of honeysuckle, 2 to 4 parts of pseudo-ginseng, 3 to 6 parts of fushen, 5 to 13 parts of platycladi seed, 5 to 13 parts of asparagus root, 4 to 8 parts of leech, 2 to 4 parts of Szechuan lovage rhizome, 5 to 13 parts of schisandra, 3 to 12 parts of licorice, 3 to 6 parts of polygala root, 1 to 2 parts of cinnabar and the like which are used as raw materials, creatinine, vitamin C, coenzyme Q10 and the like. The medicament combines Chinese medicine and western medicine, treats both symptoms and root causes, and has the effects of diminishing inflammation, resisting viruses, nourishing liver, nourishing yin, clearing heat, enriching qi and blood, tranquilizing by nourishing the heart, eliminating the pathogen and strengthening the vital qi. After patients administrate the medicament, the treatment effect is ideal, and the viral hepatitis symptom is obviously improved or disappears.
Owner:CHENGDU JIANJIANG PHARMA FACTORY

High-flux dry-type chemical detection device

The invention discloses a high-flux dry-type chemical detection device. The high-flux dry-type chemical detection device comprises a pedestal, a sample introduction pedestal, a transmission mechanism,a temperature controlled incubation module, and an optical detection module; the pedestal is of a U-shaped structure; the center of the pedestal is provided with a lower groove, wherein the lower groove is capable of penetrating the pedestal; the transmission mechanism is arranged in the lower groove, and is used for automatic pushing of reagent sheets; the pedestal is provided with a rail cover;the rail of the rail cover is arranged to be parallel and corresponding to the lower groove; the rail is provided with a pushing block through clamping, and the pushing block is used for hand-operated pushing of reagent sheets; one end of the rail is provided with the sample introduction pedestal, the temperature controlled incubation module, and the optical detection module successively. The high-flux dry-type chemical detection device can be used for rapid quantitative determination of biochemical indexes, including glucose, creatinine, glutamic-pyruvic transaminase, and urotoxin in clinical blood samples. The high-flux dry-type chemical detection device is simple in structure, high in detection efficiency, high in stability, and is convenient to use.
Owner:SUZHOU INST OF BIOMEDICAL ENG & TECH CHINESE ACADEMY OF SCI
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