606 results about "Carnosine" patented technology

A topical composition comprising a lipoic acid, a carnitine, and a carnosine in a suitable vehicle for topical application and a method for treating skin is provided. The present compositions are useful in improving the appearance of aged skin characterized by wrinkles and loss of elasticity. Preferred components include R-lipoic acid or R-dihydrolipoic acid, acetyl-1-carnitine, and 1-carnosine.

A topical composition comprising a lipoic acid, a carnitine, and a carnosine in a suitable vehicle for topical application and a method for treating skin is provided. The present compositions are useful in improving the appearance of aged skin characterized by wrinkles and loss of elasticity. Preferred components include R-lipoic acid or R-dihydrolipoic acid, acetyl-1-carnitine, and 1-carnosine.

Methods of producing a protein in cell culture comprising an anti-senescence compound, such as the antioxidant carnosine, are provided. According to teachings of the present invention, cells grown in a cell culture medium comprising an anti-senescence compound exhibit increased viability and productivity. Furthermore, cell cultures grown in the presence of an anti-senescence compound exhibit decreased levels of high molecular weight aggregates in the cell culture medium.

The invention relates to the technical field of cosmetics, and discloses a nona-oligopeptide composition for skin repairing and application thereof. The nona-oligopeptide composition is prepared from, by weight, 1-30 parts of palmitoyl-tripeptide-1, 1-30 parts of tripeptide-1 copper, 1-50 parts of palmitoyl-tripeptide, 1-30 parts of carnosine, 1-30 parts of acetyl tetrapeptide-5, 1-30 parts of palmitoyl-tetrapeptide-7, 0.1-30 parts of acetyl hexapeptide-8, 0.1-30 parts of nonapeptide-1, and 1-30 parts of nisin. The nona-oligopeptide composition has the effect of a cell factor sample, affects the growth of skin flora, is applied to dermatology and skin beautifying, and has the effects of repairing skin lesion, adjusting metabolism and inhibiting skin condition conditioned pathogen growth.

The invention discloses an external skin care product capable of adjusting skin immunity and delaying skin aging. The external skin care product is characterized by comprising powder, an aqueous solution and emulsion, wherein the powder comprises oligopeptide-1 and ginsenoside; the aqueous solution comprises glycyrrhiza glabra root extract, artemisia capillaris flower extract, mulberry root extract, jujube fruit extract, scutellaria root extract, hydrolyzed rice protein and nicotinamide; and the emulsion comprises hgytantriol bifida ferment lysate, creatine, carnosine, alpha glucosyl hesperidin, hexapeptide-3, centella asiatica extract, coenzyme Q10 inclusion complex, opuntia ficus-indica stem extract, rhodiola rosea extract, saussurea involucrate extract, pseudo-ginseng root extract and Chinese angelica extract inclusion complex. According to the external skin care product, the powder, the aqueous solution and the emulsion are jointly used, and the external skin care product can reduce wrinkle and pachulosis, even skin tone and improve skin elasticity and skin firmness, so that the skin is finer and smoother and looks young.

The invention discloses a polypeptide composition for repairing, whitening and removing wrinkles. The polypeptide composition for repairing, whitening and removing the wrinkles is prepared from the following components is percentage by weight: a repairing polypeptide composition, a collagen supplementing polypeptide composition, a wrinkle removing polypeptide composition, a skin-brightening polypeptide composition, a small molecular active substance, a skin-care activating agent, a pH (Potential of Hydrogen) regulator, a plurality of auxiliary agents and the balance of water, wherein the repairing polypeptide composition comprises palmitoyl tetrapeptide-7 and tripeptide-1-copper; the collagen supplementing polypeptide composition comprises palmitoyl tripeptide-1, palmitoyl tripeptide-5 andpalmitoyl pentapeptide-4; the wrinkle removing polypeptide composition comprises acetyl hexapeptide-8, dipeptide diaminobutyroyl benzylamide diacetate and melittin; the skin-brightening polypeptide composition comprises nonapeptide-1, carnosine and tetrapeptide-30. According to the polypeptide composition disclosed by the invention, a novel formula is formed through adjusting ratios of differentpolypeptide components, so that polypeptide effects with different focuses and different applicable ranges; the monarch, minister, assistant and guide thought in traditional Chinese medical science isapplied to the polypeptide composition, so that the formula is diversified and the maximum applicability and applicable range are realized.

The invention provides compositions for stimulating the formation of one or more extracellular matrix components that contain a lipoaminoacid derivative of the tripeptide carnosine such as N-Octanoyl Carnosine. Also provided are compositions containing N-Octanoyl Carnosine in combination with selected tripeptide and / or tetrapeptides as well as pharmaceutical and / or cosmetic compositions containing such compositions. The invention further provides methods of using the compositions and compositions of the invention to treat, alleviate, and / or ameliorate a symptom, condition, disorder, or disease of the skin or mucosa, wherein the symptom, condition, disorder, or disease is associated with changes in extracellular matrix components.

The invention discloses a compound anti-wrinkle anti-aging essence containing a plurality of small molecular peptides and a preparation method of the essence. The essence comprises the following raw materials in percentage by weight: 0.1-0.2% of sodium hyaluronate; 0.2-0.3% of acrylic acid (ester) / C10-30 alkanol acrylate cross-linked polymer; 5-7% of glycerol; 4-6% of 1,3-butanediol; 0.3-0.5% ofdipeptide diaminobutyl benzyl amide diacetate; 0.2-0.3% of palmitoyl tetrapeptide-5; 0.3-0.5% of palmitoyl tripeptide-1; 0.3-0.5% of palmitoyl pentapeptide-4; 0.1-0.3% of carnosine; 0.1-0.3% of serine; 0.1-0.3% of arginine; 0.1-0.3% of nicotinamide; 0.2-0.3% of a preservative and the rest of deionized water. The skin of a human body is repaired in an all-round way, so that good and rapid wrinkle removal and aging resistance effects are achieved.

Personal care compositions containing at an alpha-glucan and / or beta-glucan; at least one additional skin and / or hair care active selected from the group consisting of sugar amine, vitamin B3, retinoids, peptides, phytosterol, dialkanoyl hydroxyproline, hexamidine, salicylic acid, n-acyl amino acid compounds, sunscreen actives, water soluble vitamins, oil soluble vitamins, hesperedin, mustard seed extract, glycyrrhizic acid, glycyrrhetinic acid, carnosine, Butylated Hydroxytoluene (BHT) and Butylated Hydroxyanisole (BHA), menthyl anthranilate, cetyl pyridinium chloride, ergothioneine, vanillin or its derivatives, diethylhexyl syrinylidene malonate, melanostatine, sterol esters, tetrahydrocurcumin, their derivatives, their precursors, and combinations thereof; and a dermatologically acceptable carrier.

The invention discloses a cosmetic composition for delaying skin aging, the main component of the cosmetic composition is a frankincense extract or an oat extract or the mixture of the two, and the auxiliary components comprise palmitoyl pentapeptide and carnosine. The cosmetic composition is characterized in that natural herbal extracts are taken as main raw materials, small molecule peptide active additives are compounded, all the components are reasonably combined, matched and used together under the premise of maintaining the normal physiological metabolism and the functions of skin, and the effect of delaying the skin aging is achieved through a variety of ways and actions of the components.

The invention discloses a cosmetic composition favorable for keeping the biological activity of an epidermal growth factor (EGF). The composition mainly comprises the EGF, hydrolyzed collagen powder, sodium hyaluronate, silk peptide powder, palmitoyl pentapeptide and carnosine. The cosmetic composition disclosed by the invention has the characteristics that polypeptides with different structures and molecules are used as main raw materials, polysaccharides are compounded, and various components are similar to the EGF in structure, thereby protecting the EGF; and under the protective action of multiple components which are reasonably combined and matched, the biological activity of the EGF in a cosmetic formula is kept.

The invention discloses a skin bottom essence containing herba dendrodii officinalis extract and a preparation method thereof. The skin bottom essence is prepared from the following components of herba dendrodii officinalis extract, a tremella extracting solution, carnosine, acetyl hexapeptide-8 liquid, alpine plant extract, vitamins and vitamins thereof, allantoin, glucan, sodium hyaluronate, a moisture absorbent, an emulsifier, a nanometer micro-emulsion, an appearance modifier, a thickener, arginine, EDTA-2Na (ethylenediamine tetraacetic acid disodium salt), inhibition stimulation factors,a preservative, essence, and deionized water. The skin bottom essence has the advantages that the herba dendrodii officinalis extract, the tremella extracting solution, a radix gentianae extracting solution, carnosine, the acetyl hexapeptide-8 liquid, the alpine plant extract, and the nanometer micro-emulsion are contained; the functional ingredients are promoted to be absorbed and permeated intothe deep layer of skin, the skin cells can be activated, reactive nitrogen species can be cleared away, the skin metabolism can be promoted, the micro-circulation can be improved, and the protein synthesis of skin can be promoted; the effects of supplementing water and moisturizing, maintaining elasticity, tightening and brightening, and reducing small wrinkles are realized, and the natural agingof the skin is delayed.

The invention discloses an anti-ageing skincare product. The anti-ageing skincare product comprises 0.001 to 3 weight percent of a plant stem cell active matter and 0.01 to 3 weight percent of Dragosine carnosine, wherein the plant stem cell active matter is at least one of a Phytocelltec<TM> Malus Domestica apple stem cell, a Phytocelltec <TM> Solar Vitis grape stem cell, a Phytocelltec <TM> Alp Rose rose leave stem cell, a Phytocelltec <TM> Argan nut stem cell and a Regenistem Rice Ap red rice stem cell. The preparation method of the anti-ageing skincare product comprises a step of adding the plant stem cell active matter and the Dragosine carnosine into a skincare product. The anti-ageing skincare product comprises the plant stem cell active matter and the Dragosine carnosine at the same time, and under the synergistic action of the two components, the anti-ageing skincare product can obviously improve skin quality, skin elasticity and proliferative capacity of skin, and the effect is obviously higher than that of a skincare product in which the plant stem cell active matter or the Dragosine carnosine is added singly.

The invention discloses a moisturizer with a long-lasting moisturizing effect and a preparation method thereof. The moisturizer is prepared from the following raw materials, in percentage by mass: 10-25% of long-acting moisturizing complexing agent, 55-75% of solvent, 1-5% of emulsifying agent, 10-30% of skin-moistening grease, 0.2-1.5% of stabilizer, 0.01-1% of pH conditioning agent, 1-10% of skin conditioner, 0.1-1% of preservative and 0.03-0.5% of aromatic. The moisturizer is characterized that the ingredients of moisturizing combination include a purple coneflower extract, a sugar maple extract, saccharomycetes / rice fermented product filter liquid, sodium lauroyl lactylate, ceramide 3, ceramide 6II, ceramide 1, phytosphingosine, phytosterol and carnosine, the moisturizer has the moisturizing effect as long as 4-8 hours by optimizing the formulation and adding proportion of the long-acting moisturizing complexing agent.

The invention discloses a preparation method of a polypeptide silk facial mask, which comprises the steps of fully mixing polypeptide powder and silk protein nutrient solution and cooling. Polypeptide powder is mainly composed of aloe vera, carnosine, oligopeptide, soluble collagen, 2‑o‑ethyl ascorbic acid, betaine, trehalose, niacinamide, allantoin; the protein nutrient solution of silk is mainly composed of water, glycerin, Propylene glycol, butylene glycol, malto-oligosaccharide glucoside, hydrogenated starch hydrolyzate, glycerol polymethacrylate, PVM / MA copolymer, carbomer, sodium hyaluronate triethanolamine, baobab pulp extract, tranexamic acid , Centella asiatica extract, dipotassium glycyrrhizate and other skin conditioners or moisturizers. Through the combination of polypeptide powder and silk protein liquid, it can effectively give fresh nutrition to the skin, promote the skin repair process, strengthen the nutrient absorption capacity, deeply nourish, smooth and rejuvenate the skin, and make the skin elastic.

The invention discloses an anti-aging cosmetic skin care product, which contains 0.001-3wt% of plant stem cell actives and 0.01-3wt% of Dragosine carnosine. The plant stem cell actives are PhytocelltecTM MalusDomestica apple stem cells, PhytocelltecTMSolarVitis grape stem cells, PhytocelltecTMAlpRose rose leaf stem cells, PhytocelltecTMArgan At least one of nut stem cells and RegenistemRiceAp red rice stem cells, and its preparation method: adding plant stem cell active substances and Dragosine carnosine to beauty and skin care products. The product of the present invention contains plant stem cell active substance and Dragosine carnosine at the same time. Under the synergistic effect of these two components, the product can obviously improve skin quality, improve skin elasticity, and improve skin proliferation ability, and the effect is obviously higher than adding plant stem cell active substance alone or Dragosine Carnosine.

The invention provides a composition for moisturizing and nourishing facial cream. The composition comprises effective components in parts by weight as follows: jojoba seed oil, avocado tree fruit grease, a purslane herb extract, phytosterol isostearate, mycose, decarboxy carnosine HCL, tocopheryl acetate, a Chinese angelica root extract, a baical skullcap root extract, sodium hyaluronate, aloe barbadensis leaf juice, a ginseng root extract and a centella leaf extract. The composition is applied to the facial cream, can provide lasting moisturizing and water supplement functions for the face, and can whiten the skin and resist wrinkles obviously after being used for a long time.

The invention provides a skin barrier repairing complex, facial cream and a preparation method therefor. The skin barrier repairing complex comprises a composition for repairing skin barrier, hydroxylasiaticoside, deacidified carnosine, a glycyrrhiza inflata root extract, a radix scutellariae extract and a hamamelis extract, wherein the composition for repairing skin barrier comprises sea fennelcallus culture filtrate, Ectoin and a hydrolyzed red alga extract. The skin barrier repairing complex can achieve triple effects of simultaneously repairing cutin barrier, repairing immunologic barrier and strengthening microbiologic barrier; and the facial cream prepared from the skin barrier repairing complex is obvious in repairing effect and can be used for effectively improving hydrature of skin, increasing the content of hyaluronic acid in the skin, improving photoaging, helping cell saccharification reversing and reducing fine grain area.

The invention relates to the food scientific and technical field, and aims at providing a seafood flavoring prepared by using shrimp shell and a preparation method. The seafood flavoring is prepared by compounding the following components by weight percentage: 60%-70% of shrimp shell extract, 8%-15% of monosodium glutamate, 12%-20% of salt, 5%-10% of white sugar, 0.2%-0.5% of clove powder, 0.3%-0.6% of pepper, 0.2%-0.5% of fennel powder and 0.5%-1.0% of anti-oxidant. The components of the present invention have the advantages of reasonable compatibility, low production cost, good mouthfeel, delicious taste and abundant nutrients. The seafood flavoring contains rich active peptide, carnosine, amino acid, nucleotide, vitamin and trace elements, particularly to astaxanthin with the functionsof antioxidation, aging resistance, anti-tumor, cardio-cerebrovascular disease prevention and the like, the seafood flavoring is a good marine organism product.

The invention discloses a high-quality collagen mask. The high-quality collagen mask is prepared from, by weight, water, glycerin, dipropylene glycol, methylpropanediol, SC glucan, super repair peptide, carnosine, fucogel-1, milk skin conditioner, dipotassium glycyrrhizinate, hydrolyzed collagen, allantoin, preservative, citric acid, methylparaben, sodium hyaluronate, EDTA disodium, PEG-hydrogenated castor oil and essence. The adopted raw materials are free of toxicity, irritation or side effect. The high-quality collagen mask has higher permeability, trophism, repairability, moisture retention property and compatibility and better whitening and wrinkle removing functions than masks available in the market at present, and can improve skin elasticity, shrink pores, remove facial wrinkles, improve dark and oily skin, deeply permeate into skin to provide nutrients and water for skin constantly, and repair aged and damaged cells, so as to realize a long-term skin nourishing effect.

The invention discloses an under-forest raising method of local chickens. The method comprises following steps of: place construction, disinfection processing, temperature regulation, water boiling and feeding. The under-forest raising method of local chickens has following beneficial effects: chickens are brooded via chicken coops and open under-forest raising is performed such that local chickens enhance health effectively via feeds and improve capabilities of adapting to the environment; local chickens in the forest absorb nutrition by their own by picking and eating pests so that growth of trees is promoted; chicken manure left behind by local chickens can be utilized as organic fertilizers of forests; the raising method helps to increase content of free polysaccharide, free amino acid material, free nucleoside material and carnosine in muscles of local chickens such that obvious fresh and sweet flavor is obtained; proportions of albumin, nucleic acid and polysaccharide in muscles of local chickens are increased so that obvious tender and cool feeling is obtained; the under-forest raising method helps to improve immunities, reduce or avoid the use of antibiotics so that digestive absorption performance is effectively enhanced; and the method is featured by being eco-friendly and being low in raising cost.

The invention discloses vegetable protein peptide wrinkle reducing and resilience restoring eye cream. The eye cream is mainly prepared from, by mass, 0.1% to 0.3% of carnosine, 0.3% to 0.7% of hexapeptide-9 / butanediol and 0.3% to 0.8% of tiny euglena polysaccharide / hydrolyzed collagen. According to the prepared vegetable protein peptide wrinkle reducing and resilience restoring eye cream, multiple aging delaying ways are comprehensively applied, carnosine, hexapeptide-9 / butanediol and tiny euglena polysaccharide / hydrolyzed collagen with the specific ratio are adopted and cooperate with one another, and the remarkable effects of skin tightening, restoring, wrinkle resisting and skin improving are achieved. Therefore, the eye cream has the effects of whitening, skin tendering, skin tightening and wrinkle reducing.

The invention provides composition for moisturizing and nourishing eye serum. The composition comprises effective components in parts by weight as follows: jojoba seed oil, squalene, avocado tree fruit ester, a xanthan gum / glucose / chondrus crispus extract, mycose, acetyl tetrapeptide, a rhodiola extraction solution, tocopheryl acetate, sodium hyaluronate, decarboxy carnosine HCL, a kudzuvine root extract and a glycyrrhiza glabra root extract. The composition is applied to the eye serum, can nurse the delicate skin around eyes, can realize lasting moisturizing and water supplement effects, and can activate blood around the eyes, obviously improve black eyes and smooth dry lines of the eyes after being used for a long time.

The invention discloses a polypeptide essence solution for improving the skin texture. The polypeptide essence solution is prepared from propylene glycol, diglycerin, glycerin, butanediol, nicotinamide, polyethylene glycol-8, a PEG / PPG-17 / 6 copolymer, hamamelis water, a glycerin acrylate / acrylic acid copolymer, a PVM / MA copolymer, palmitoyl hexapeptide-14, tripeptide-1, acetyl hexapeptide-8, pentapeptide-3, dipeptide diaminobutyryl benzyl amide diacetate, 1,2-hexanediol, betaine, tapioca starch, an ammonium acryl dimethyl taurine / VP copolymer, carbomer, acetyl chitosamine, a white willow barkextract, papain, sodium hyaluronate, octylene glycol, collagen, PEG-40 hydrogenated castor oil, hydroxyethyl cellulose, oligopeptide-1, a wild soybean seed extract, carnosine, disodium EDTA, octyl hydroxamic acid, rosa damascene flower oil and water. The polypeptide essence solution takes polypeptide tightening molecules as a main raw material, can awaken the skin vitality, maintain the skin elasticity, enhance the tightness, ameliorate fine lines, brighten the skin color, improve the skin texture, and rejuvenate the skin.

A method and composition for stimulating the proliferation and differentiation of stem cells is used to self-repair injury in mammals. A supplement is administered having an effective dose of blueberry, carnosine, catechin, green tea extract, VitaBlue, Vitamin D3 or combinations of these. For example, a therapeutic amount of two or more of the supplements may be selected having a synergistic effect, allowing a lower dose to achieve the same or greater effective protection as a higher dose of any one of the supplements.

The invention provides a composition for a hydrating and nourishing mask. The composition is prepared from, by weight, decarboxylated carnosine HC1, simmondsia chinensis seed oil, trehalose, arctic root extract, salvia extract, tocopheryl acetate, aloe barbadensis leaf juice, allantoin, sodium hyaluronate, asiatic pennywort herb leave extract, glycyrrhiza glabra root extract, xanthan gum, chondrus crispus extract and glucose. The composition is used for the mask, the long nourishing effect and the long hydrating effect on the face can be provided, and meanwhile the skin can be obviously whitened after long-time use.

The invention relates to a whitening composition (uniGlow) and an application thereof. The whitening composite comprises phenylbenzimidazole sulfonic acid, hydroxyphenylpropylamide benzoic acid, dipotassium glycyrrhizinate, undecylenoyl phenylalanine, hydrolyzed shellfish protein, beta-arbutin, ellagic acid, sodium ascorbate phosphate, carnosine, nicotinamide, inositol, papain and hesperidin extract. The whitening composition performs targeted inhibition from the melanin forming inducements of UV, inflammatory factors, melanoma and endothelin; in the melanin synthesis process, tyrosinase inhibits the reduction with a melanin intermediate, blocks the melanin transfer pathway, accelerates stratum corneum spalling and accelerates the metabolism; by conditioning, the skin is fine, tight, natural, white and bright.

The invention provides aminopeptidase for catalytic synthesis of carnosine, and a preparation method and application thereof. The aminopeptidase has the amino acid sequence shown by SEQ ID NO:2. For the preparation of biological enzymes, firstly, a gene engineering strain of the biological enzymes is built; the biological enzyme gene fragment obtained through full gene synthesis is subjected to linearized plasmid recombination by using restriction enzymes SalI. The built gene-engineered strain is suitable for high-density culture; the exoenzyme is biologically synthesized; solid-liquid separation is performed; ultrafiltration concentration is performed to obtain enzyme liquid; histidine and beta-alanine can be catalyzed in normal-temperature and normal-pressure water solution to efficiently synthesize carnosine; the reaction environment is friendly; the production cost is low; the conversion time is short; the process operation is simple; the reaction system impurity content is low; the post treatment is easy; the wide prospects of large-scale industrial application are realized.