882 results about "Active matter" patented technology

This invention provides an apparatus and method for injecting gas within a plasma reactor and tailoring the distribution of an active species generated by the remote plasma source over the substrate or wafer. The distribution may be made more or less uniform, wafer-edge concentrated, or wafer-center concentrated. A contoured plate or profiler is provided for modifying the distribution. The profiler is an axially symmetric plate, having a narrow top end and a wider bottom end, shaped to redistribute the gas flow incident upon it. The profiler is situated below an input port within the plasma reactor chamber and above the wafer. The method for tailoring the distribution of the active species over the substrate includes predetermining the profiler diameter and adjusting the profiler height over the substrate. A coaxial injector tube, for the concurrent injection of activated and non-activated gas species, allows gases (or gas mixtures) to be delivered in an axially symmetric manner whereby one gas can be excited in a high density RF plasma, while the other gas can be prevented from excitation and / or dissociation caused by exposure to the plasma or heated surfaces in the source apparatus. The gas admixture that is not to be excited or dissociated prior to contact with the wafer surface is shielded from direct exposure to the RF field surrounding the plasma confinement tube. The tube walls are also shielded from the infrared energy emitted from the plasma. The profiler is used in conjunction with the coaxial injector tube for redistributing the excited gases emerging from the injector tube, while allowing the non-excited gases to pass through its center.

This invention provides novel methods for the formation of biocompatible membranes around biological materials using photopolymerization of water soluble molecules. The membranes can be used as a covering to encapsulate biological materials or biomedical devices, as a “glue” to cause more than one biological substance to adhere together, or as carriers for biologically active species. Several methods for forming these membranes are provided. Each of these methods utilizes a polymerization system containing water-soluble macromers, species, which are at once polymers and macromolecules capable of further polymerization. The macromers are polymerized using a photoinitiator (such as a dye), optionally a cocatalyst, optionally an accelerator, and radiation in the form of visible or long wavelength UV light. The reaction occurs either by suspension polymerization or by interfacial polymerization. The polymer membrane can be formed directly on the surface of the biological material, or it can be formed on material, which is already encapsulated.

The present invention relates generally to transscleral, transcorneal, and transocular delivery of biologically active substances through the tissues, blood vessels and cellular membranes of the eyes of patients without causing damage to the cellular surface, tissue or membrane. The invention provides compositions and methods for enhanced transscleral, transcorneal and transocular delivery of biologically active substances using pulsed incoherent light, and particularly the transcleral, transcorneal or transocular delivery of high molecular weight biologically active substances to a patient using pulsed incoherent light. The invention further provides a device for the application of the pulsed incoherent light to cellular surfaces and membranes of the eye of a subject using those compositions and methods.

The invention discloses a bacillus belleus GT11 and application thereof. The bacillus belleus CT11 is collected at China General Microbiological Culture Collection Center on December 13th, 2016; the collection number is CGMCC No.13446; the bacillus belleus CT11 can be prepared into water agent, wettable powder or coating material and can be used for preventing and controlling the root rot diseases of pseudo-ginseng and plukenetia volubilis and Chinese cabbage clubroot. The invention provides an efficient, nontoxic, safe, non-residual and conveniently used biological agent for preventing and controlling the diseases such as root rot and clubroot; the effective active ingredient is bacillus belleus CT11 strain; the strain can generate the secondary metabolite antimicrobial active matter, is capable of degrading the cell wall of pathogenic bacteria and has an excellent growth-promoting effect for the crops, such as, plukenetia volubilis, pseudo-ginseng and Chinese cabbage; besides, the bacillus belleus CT11 has a better antibacterial effect for pseudo-ginseng phytophthora sojae, pseudo-ginseng fusarium solani, plukenetia volubilis gray mold, paddy bacterial mycosphaerella, and the like.

A device to enhance the delivery of a drug or other substance of interest into a selected organ or tissue, comprising special electrodes, one of the electrodes carrying a container with the selected drug or other substance of interest, said electrodes being capable of being positioned at preselected locations of said organ or tissue, wherein the electrodes are all connected with a selected energy source which generates and maintains an energy field before and during the enhanced delivery of said substance, under the influence of which delivery is accomplished in a direction from the active to the passive electrode and into said organ or tissue. The energy source may be selected from suitable sources providing an electric field, a magnetic field, ultrasonic waves, high energy waves like laser beams, or a combination thereof. Further a method for the enhanced delivery of said drug or other substance of interest to an internal organ or target tissue of an organism, for example the brain, bypassing the blood-brain barrier, is disclosed.

A device to enhance the delivery of a drug or other substance of interest into a selected organ or tissue, comprising special electrodes, one of the electrodes carrying a container with the selected drug or other substance of interest, said electrodes being capable of being positioned at preselected locations of said organ or tissue, wherein the electrodes are all connected with a selected energy source which generates and maintains an energy field before and during the enhanced delivery of said substance, under the influence of which delivery is accomplished in a direction from the active to the passive electrode and into said organ or tissue. The energy source may be selected from suitable sources providing an electric field, a magnetic field, ultrasonic waves, high energy waves like laser beams, or a combination thereof. Further a method for the enhanced delivery of said drug or other substance of interest to an internal organ or target tissue of an organism, for example the brain, bypassing the blood-brain barrier, is disclosed.

The invention relates to a cosmetic moisturizer containing xylitol. The cosmetic moisturizer consists of the following raw materials by weight: 2-10 parts of a moisturizer, 0.1-2 parts of lipa, 5-15 parts of an emulsifier and 60-80 parts of water. The cosmetic moisturizer is made from pure natural plant products, is non-toxic and harmless, and has ecological environmental protection function. The cosmetic moisturizer can diffuse into deep skin and combine with deep water, thus keeping the skin moistened. Compared with other moisturizers, the cosmetic moisturizer has better hydroscopicity when the content of active matter is the same, and the moisturizer has the function of keeping moisture well.

The subject of this invention is a controlled release composition for zootechnical use. In particular, the subject of this invention is a composition comprising micro-pellets that are able to release the physiologically active substances they contain in a controlled manner. In addition, this invention refers to a procedure for preparing said composition as well as the use of said composition in the zootechnical sector.

An object of the present invention is to provide a method for introducing a physiologically active substance such as a gene into a cell, which introduces a physiologically active substance such as any given gene into any given cell in a view under a microscope, while significantly reducing invasiveness to the cell, and a device used for the above method. The present invention provides a method for introducing a physiologically active substance into a cell, which comprises: allowing a physiologically active substance to attach around a needle having a diameter of 500 nm or less, provided that it is able to be inserted into a cell; and inserting the above-described needle into the cell; and a microinjection device for carrying out the aforementioned method.

The present invention relates to a sheet or tubular structure consisting of biocompatible material, which is elastic and comprises at least one biologically active substance in at least one region and to a sheet or tubular structure, which comprises at least one biologically active substance release-modifying agent in at least one region as well as an implant covered at least partially by the sheet or tubular structure of the invention. The present invention further provides a method and an apparatus for producing, and preferably customizing and / or optimizing, the sheet or tubular structure of the invention. The sheet or tubular structure of the invention can be customized / optimized before implantation in the operating room.

The invention discloses a blautia sp. AUH-JLD56 and an application thereof in the conversion of arctigenin, and belongs to the technical field of bacterium. The preservation number of blautia sp. AUH-JLD56 is CGMCC No. 8032. The application of blautia sp. AUH-JLD56 comprises following steps: (1) culture of bacterium strain AUH-JLD56; (2) co-culture of a substrate, namely a coarse product of arctigenin, and a bacterium strain AUH-JLD56 and separation and purification of metabolite. The bacterium strain AUH-JLD56 can high effectively convert a coarse product of arctigenin in the traditional Chinese medicine actium lappa to 3'-demethylated-arctigenin, solves the 3'-demethylated-arctigenin resource shortage problem, and lays a foundation for researching and developing microorganism metabolite of pharmacological active substance in actium lappa.

Preparation of particles of an active substance having a layer of an additive at the particle surfaces, by dissolving both the active substance and the additive in a vehicle to form a target solution, and contacting the target solution with an anti-solvent fluid using a SEDS(TM) particle formation process, to cause the active substance and additive to coprecipitate. The additive is typically a protective additive, in particular a taste and / or odour masking agent. Also provided is a particulate coformulation made by the method, which has a finite gradient in the relative additive concentration, which concentration increases radially outwards from the active-rich core to the additive-rich surface of the particles.

The invention relates to a preparation method of a composite whitening lipid nanoparticle emulsion, which mainly comprises the following steps of: (A) weighing lipid materials, and heating to 75-85 DEG C to obtain a liquid oil phase; (B) proportionally weighing tetrahydrocurcumin, glycyrrhiza glabra root extract and tetrahydropiperine and mixing to obtain a composite whitening active matter; (C) adding the composite whitening active matter into the liquid oil phase, and mixing uniformly; (D) weighing an emulsifier and distilled water, heating to 75-85 DEG C, and mixing uniformly to obtain a liquid water phase; and (E) mixing the liquid oil phase and the liquid water phase, carrying out circular homogenization for 5-15 times through a high-pressure homogenizer under the conditions that thepressure is 70-150MPa and the temperature is 75-90 DEG C, keeping the temperature of the mixed liquid at the outlet section of the high-pressure homogenizer to be lower than 90 DEG C, cooling to roomtemperature, and adding a proper amount of preservative so as to obtain the composite whitening lipid nanoparticle emulsion. The emulsion prepared by the preparation method provided by the invention has good stability and obvious whitening effect, basically does not discolor, and is convenient to be blended in a cosmetic formula in a cooling mode.

The invention discloses finishing technology for aromatic anti-bacteria cotton textile, which comprises the steps of extraction of active matters of plants, preparation of natural germicide and chitosan cross-linking and finishing technology of the cotton textile; finished knitted or machine-made cotton textile has long-time aroma and has health-care effect such as broad-spectrum bacteriostasis, sterilization, desinsectization and the like; in addition, the cotton textile disclosed by the invention has very good washability; and the cotton textile can be prepared as a plurality of knitted or machine-made health-care fabrics such as bras, underwear, pants, pajamas, pillowcases, bed sheets and the like.

The invention provides a lithium ion capacitor and a negative electrode plate thereof and a manufacturing method of the negative electrode plate. The negative electrode plate of the lithium ion capacitor comprises a current collector copper foil, an active matter layer and a pre-lithiation matter layer, wherein the active matter layer is arranged on the current collector copper foil and provided with active matters having embedded and / or stripped from lithium ion performance, and the pre-lithiation matter layer is arranged on the active matter layer. The manufacturing method of the negative electrode plate of the lithium ion capacitor includes steps of coating active matter sizing on the current collector copper foil and drying and rolling the same; spraying or sputtering pre-lithiation sizing on the dried current collector copper foil coated with the active matter sizing, and drying and rolling to obtain the negative electrode plate of the lithium ion capacitor, wherein the active matter sizing contains the active matters embedded and / or stripped from lithium ion performance. The lithium ion capacitor comprises the negative electrode plate which is manufactured by the above manufacturing method. The lithium ion capacitor has the advantages that each layer of the negative electrode plate is good in lithium embedded uniformity and consistency, lithium embedding time is short, carrying a preset quantity of lithium by the negative electrode plate can be effectively controlled and the like.

The invention provides a preparation and application method for treating a catalyst of industrial waste water. The preparation method of the invention adopts a molecular sieve as a carrier, one or a plurality of P-type semiconductor oxides such as MnO2, CeO2, Ag2O, CuO, etc. is / ,are loaded on the molecular sieve in a way of ion-exchange and finally a supported catalyst containing the P-type semiconductor oxides is obtained through molding; and the catalyst is used when ozone and light are coexisted. The preparation and application method of the invention aims at the disadvantages of that active constituents of the catalyst and an addition agent in the combination technique of ozone and catalyst are lost easily, active constituents are loaded on the molecular sieve carrier in the way of ion-exchange so as to improve the combination binding capacity of the active constituents and the carrier; and an electronic addition agent can be substituted through a light electro-donating effect, so as to effectively provide electrons in a long term and promote the catalyst and the ozone to generate active matters; the coaction of the catalyst and the ozone can enhance the activity stability of the catalyst and prolong service life, thus being conducive to industrialization of the technologies.

The invention relates to a tissue engineering bracket material capable of physically embedding active substances and a preparation method thereof. The tissue engineering bracket material capable of physically embedding the active substances is prepared from 100 weight parts of biodegradable macromolecular substance and 0 to 20 weight parts of active substances, wherein the weight part of the active substances is not equal to zero; 100 weight parts of biodegradable macromolecular substance consists of 50 to 100 weight parts of synthetic macromolecular substance and 0 to 50 weight parts of natural macromolecular substance; the macromolecular substances and the active substances form a micromolecular nanofiber membrane or a composite macromolecular nanofiber membrane; and the active substances are bonded on the surface of the fiber membrane uniformly. The tissue engineering bracket material capable of physically embedding the active substances has high biocompatibility and sufficient mechanical strength, can be biodegraded, is suitable for proliferation and directed differentiation of stem cells, and has the functions of promoting cell migration adhesion and capturing the stem cells so as to induce regeneration of tissues such as bones, cartilages, nerves, skin and the like.

The invention relates to a chitosan-silica sol-gel sensitive membrane for electrochemical biosensors and a preparation method thereof, and the sensitive membrane is covalently bonded with bioactive substances and doped with electron carriers and electron mediators. By means of the sol-gel process of silane coupling agent and the covalent coupling of the silane coupling agent, the bioactive substances and chitosan, the bioactive substances are covalently bonded with a synchronously formed chitosan-silica sol-gel three-dimensional mesh structure. Meanwhile, the electron carriers and the electron mediators are doped in the chitosan-silica sol-gel three-dimensional mesh structure. Compared with the prior art, the sensitive membrane for electrochemical biosensors, which is provided by the invention, can remarkably enhance the stability, selectivity and sensitivity of the sensors.

The invention provides a solid defoaming agent. The solid defoaming agent consists of the following components in percentage by weight: 50 to 90 percent of carrier, 5 to 20 percent of defoaming active matter, 0.5 to 4 percent of emulsifier, 1 to 30 percent of structural agent and 5 to 15 percent of water. A method for preparing the solid defoaming agent comprises the following steps of: (1) adding the defoaming active matter, the emulsifier and the structural agent into a mixer and fully mixing the components so as to obtain a mixture A; (2) adding an organic carrier into the mixture A and uniformly stirring so as to obtain a mixture B; (3) adding deionized water into the mixture B and uniformly stirring so as to obtain a mixture C; and (4) pelletizing the mixture C by using a pelletizer and drying the obtained particles by using a drier so as to obtain the solid defoaming agent. The solid defoaming agent has high defoaming and foam restraining performance and anti-damping performance, and can be applied to industries such as daily use chemicals, industrial cleaning and the like.

The invention provides a multi-effect restoring skin cream, which takes olive oil, simmondsia chinensis seed oil, wheat embryo oil and shea butter as the raw materials, and is prepared by the following steps: dissolving emulsifier cetearyl glucoside in an oil phase directly, slowly adding the oil in water while stirring, then adding the mixture in an emulsion pot in sequence by a filter, stirringand emulsifying the mixture for a given period of time at 70 to 80 DEG C to prepare oil / water-based emulsion body, and adding multiple pure natural plant active matters, such as aloe, trehalose, natural vitamin E, ginger extract, yeast extract and rose essential oil (natural essence). The skin cream is rich in natural plant oil, blends multiple ingredients and has the unique effect to reduce the chromatosis caused by inflammation (ultraviolet light, stimulation and acne) and aging, help skin resist the stimulation from outside, relieve the pain from heat and sensitivity, reduce the skin temperature, prevent dry and crack and further recover and maintain the natural elasticity of the skin.

The present invention discloses a troxerutin medicine with content of active matter 3', 4', 7-trihydroxy rutin over 90%. The active matter has molecular expression of C33H42O19 and molecular weight of 742.68. The preparation process includes the reaction stage comprising hydroxyethylation reaction, hot filtering and concentration; and the refining stage comprising heating, cooling, filtering and drying. The preparation process has high yield, low cost, simple and fast operation and high product quality, and is suitable for preparation of different medicine preparation forms.

Disclosed are methods for determining the presence or absence of a target nucleic acid (e.g. DNA) sequence in a sample nucleic acid, the method comprising: (a) exposing the sample to a detection agent comprising a colloid metal surface associated with a SER(R)S active species (SAS) such as an azo dye and with a target binding species (TBS) which may be PNA which is complementary to the target, and (b) observing the sample agent mixture using SER(R)S to detect any surface enhancement of the label wherein the binding of the TBS to the target sequence causes surface enhancement SAS. The detection agent may be exposed to the sample in step (a) as two or more separate components and will generally comprise a first agent and a second agent each having a different TBS, each TBS being capable of binding to the target sequence, and wherein the binding of the first and second TBS to the target sequence brings a metal surface associated with each TBS into proximity thereby causing surface enhancement of an SAS associated with one or both of the metal surfaces.

The invention relates to a capsule containing different active substance pellets with at least two different active substances which differ in their release profile in the gastro-intestinal tract, these active substances being selected from among the vitamins, minerals, trace elements, unsaturated fatty acids, amino acids and / or plant extracts and substances. The different release profiles represent rapid, moderate and / or slow dissolving of the active substance pellets. This controlled release leads to a targeted absorption of the active substances in the different absorption areas of the gastro-intestinal tract. Using the preparation provided according to the invention it is also possible to improve bioavailability to a high degree even when a large number of active substances are present.

The invention relates to a natural surface active agent for cleaning fruits and vegetables, which is designed for overcoming the defects that the prior cleaning agent has non-thorough secondary cleaning, is harm to a human body after long terms of use, is not easily degraded, can cause secondary pollution, and the like. The natural surface active agent is prepared from the following components by weight percent: 10-40 percent of active matter extract of Chinese soaphberry with the concentration of 30-40 percent, 10-40 percent of alkyl poly-glycosides (APG) with the concentration of 47 percent, 10-30 percent of ginger extract with the concentration of 5 percent, 0.1-0.5 percent of EDTA, 0.3-1 percent of sodium chloride, citric acid and appropriate water. The method comprises the following steps: adding 20 percent of deionized water in a reaction vessel; heating to 35-40 DEG C, then sequentially adding APG, the active matter extract of Chinese soaphberry, the ginger extract and the EDTA, and fully mixing and stirring evenly during addition; adding appropriate citric acid; cooling to room temperature; adding appropriate sodium chloride, fully stirring for 0.5 hour and aging for 1.5 hours to obtain finished product; and bottling for leaving factory. The main components of the natural surface active agent are natural products and derivatives thereof, and the invention has the advantages of good cleaning effect, no residual, easy degradation, no stimulation to skin, no side effects, no secondary pollution to environment and environmental protection.

The invention relates to a biological detergent composition. The biological detergent composition is prepared from a biological surfactant, a plant surface active agent, a biological enzyme and at least one washing auxiliary material. In the biological detergent, the biological surfactant is compounded with the plant surface active agent, the biological enzyme and other adjuvant agents. The detergent is reasonable in formula, the total content of active matters is high, and through complex synergism, the washing effect can fully meet the needs of people.

The invention discloses a kernel-shell structural nanofiber membrane, a preparation method thereof and an application; the preparation method includes steps of (1), preparation of spinning; dissolving sodium alginate, polyoxyethylene and poloxamer F127 in distilled water, stirring evenly and acquiring shell layer spinning solution; mixing the chitosan nanoparticle solution loaded with active matters with polyving akohol solution evenly, and acquiring the kernel layer spinning solution; (2), coaxial electrostatic spinning: respectively injecting the shell layer spinning fluid and kernel layer spinning fluid in a static spinning device containing a coaxial needle, performing the coaxial electrostatic spinning under room temperature, performing solvent evaporation in the spinning process, and acquiring the kernel-shell structural nanofiber membrane loaded with the nanoparticle. The preparation method is simple in operation and gentle in reaction condition and can well control the slow release of the active matter; moreover, the prepared colon targeting controlled release system has obvious colon targeting property, thereby improving the utilization degree of the active matter. The colon targeting controlled release system can be applied to functional food domain.

The invention discloses bacillus megatherium, a method for preparing a microbial inoculum through solid fermentation of the bacillus megatherium and an application of the microbial inoculum, belonging to the technical field of microbial preparations. The bacillus megatherium JSSW-JD-2F5 has been preserved in the China General Microbiological Culture Collection Center with the preservation number of CGMCC NO.8045. By adopting solid fermentation, a preparation method of a bacillus megatherium JSSW-JD-2F5 solid fermentation microbial inoculum and the application of the solid fermentation microbial inoculum are disclosed, wherein the solid fermentation microbial inoculum is used as an additive of a livestock, poultry and fishery cultivation feed and is added into the feed according to a mass percentage of 0.01-0.05%. The product of the microbial inoculum contains high-concentration viable bacteria, active enzyme and physiological active matters, and the concentration of the viable bacteria reaches more than 1.0*10<10>CFU / g and can meet requirements of a feeding microbial additive on the viable count; the application of the inoculum not only can improve the breeding environment, but also has an important significance for increasing the feed utilization ratio and promoting the growth of animals, so that the inoculum is widely applied to livestock, poultry and fishery cultivation.

A new product is described characterized by its qualities to absorb undesirable scents present in the air, while serving at the same time as a carrier for aromas, fragrances, flavorings, repellents, attractants and other active ingredients. The active ingredients are gradually released by the carrier, which is compatible with the environment and current tendencies towards the use of organic and biodegradable products. The composition comprises a carrier and an active ingredient. The carrier is characterized as being particles obtained from the milling, separation, air wash and classification of the different fractions obtained from corncobs.

The present invention relates to a kind of clear liquid type composite foliage fertilizer for wheat and its production process. The composite foliage fertilizer contains macro elements, medium elements, trace elements, chelating agent, active matter, assistant, etc. It can meet the need of wheat on Ca, Mg and other medium elements, and has reasonable collocation of organic active matter and inorganic nutritious elements and optimized surfactant and its re-compound to ensure the effective absorption on nutritious elements. It is prepared with two reaction kettles, including one chelating kettle and one pre-neutralizing kettle, and through dissolving water insoluble material and most of the chelating agent in alkali solution, neutralizing, mixing and other steps.

The invention discloses a super-concentrated washing piece and a manufacturing method thereof. The super-concentrated washing piece is prepared from 15-60% of anion active agent, 15-45% of nonionic surfactant, 1-20% of ampholytic surfactant, 2-6% of small molecule peptide compound enzyme, 1-3% of thickening agent, 0.1-0.5% of antibacterial agent, 0.1-0.3% of preservative, 0.1-1% of aromatic, 1-3% of filler and an appropriate amount of deionized water. The super-concentrated washing piece has the advantages that by adding small molecule peptide powder into compound enzyme, the excitation effect of the compound enzyme on various kinds of active matter is enhanced, and therefore the dirt-removing power of the active matter is greatly improved. Meanwhile, by means of the scientific technology that drying and enzyme spraying are carried out successively and washing piece production equipment which is independently researched and developed, it is effectively ensured that active ingredients of enzyme are not damaged.