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1052 results about "Rutin" patented technology
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Rutin, also called rutoside, quercetin-3-O-rutinoside and sophorin, is the glycoside combining the flavonol quercetin and the disaccharide rutinose (α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranose). It is a citrus flavonoid found in a wide variety of plants including citrus fruit.
Mushroom cultivating method utilizing residues of sophora flower buds after extraction of rutins
InactiveCN103229669AFull of nutritionSolve environmental problemsHorticultureCaladiumAdditive ingredient
The invention discloses a mushroom cultivating method utilizing residues of sophora flower buds after extraction of rutins. The mushroom cultivating method utilizing the residues of the sophora flower buds after the extraction of the rutins comprises processing burdening, namely weighing cultivation raw materials which comprise, based on the weight percent, cotton seed hull of 42-60%, the residues of the sophora flower buds after the extraction of the rutins of 28-40%, bran of 10-20%, gypsum of 0.6-2%, calcium superphosphate of 0.3-1%, carbamide of 0.2-1% and sugar of 0.8-2% and adding water into the cultivation raw materials after uniform mix of the cultivation raw materials to enable water content of the cultivation raw materials to achieve 55-65%; bagging and sterilizing after the burdening processing; inoculating and cultivating hypha; building a shed and earthing up; coloring; and managing fruiting. The mushroom cultivating method utilizing the residues of the sophora flower buds after the extraction of the rutins has the advantages of being simple in operation, capable of cultivating the mushroom by adding small amount of nutritional ingredients, quick in spawn runing, low in production cost and capable of effectively utilizing by-product residues in phytoextraction industries in a maximum limit and achieving sustainable development.
Owner:四川省砚山中药饮片有限公司
Method for extracting and refining rutin
ActiveCN102718820AReduce pollutionGuaranteed withdrawal rateSugar derivativesSugar derivatives preparationAlkaline waterOrganic solvent
A method for extracting and refining rutin comprises the following steps of (1) extraction: smashing raw materials, adding organic solvent into the smashed raw materials, performing extraction for 2-4 times, mixing extracting solution and concentrating the mixed extracting solution to thick extract with organic solvent content smaller than or equal to 5wt%; (2) alkali dissolution-acid sediment: adding alkaline water into the thick extract, then heating the mixture and stirring, filtering the heated mixture, regulating pH of alkaline filtrate to be 3-4, standing, filtering, drying to obtain a rutin pure product; and (3) mother liquor treatment: enabling obtained acid mother liquor to penetrate through a chromatographic column filled with resin, after the acid mother liquor penetrates through the chromatographic column, firstly using deionized water to wash a column bed until outflow liquid is neutral and colorless, introducing eluent into the chromatographic column and collecting eluate until outflow liquid is colorless, concentrating the eluate to the volume which is 5-10% of the original volume in a pressure reduction mode, cooling the concentrated eluate to achieve crystallization, filtering, using the deionized water to elute a filter cake, and drying the eluted filter cake to obtain a mother liquor rutin product. The prepared rutin is high in yield and purity, and the quality of the rutin reaches the international standard.
Owner:湖南莱崔尔生物科技有限公司
Method for extracting suaeda salsa flavone and measuring content of flavones in suaeda salsa
InactiveCN103027962AImprove production rateIncrease profitAntipyreticComponent separationConcentration gradientSolvent
Owner:YANCHENG INST OF IND TECH
Citrus aurantium total flavone extract and the preparing method thereof
The invention discloses a total chromocor extract from traditional medicine citrus fruit and preparing method, which is characterized by the following: comprising pomelo ped glycosides, new orange peel glycosides, orange peel glycosides, pomelo ped rutin, derivant and so on; choosing one or several methods from solvent extraction, solvent extraction process, macroreticular absorption resin method, lead salt precipitation method, column chromatography, supercritical fluid chromatography, liquid-liquid counter-current partition chromatography and so on; producing extract; setting percentage content of various chromocor element at 5-100%(w / w) in the extract; counting 5-100%(w / w) of pomelo ped glycosides, new orange peel glycosides, orange peel glycosides in total chromocor content.
Owner:石任兵 +1
Carbon nano tubes (CNTs) and graphene nano flakes (GNFs) synergetic enhanced aluminum-based composite and preparation method
The invention discloses a GNFs / CNTs synergetic enhanced Al / Si / Al2O3 composite. The aluminum-based composite sample is mainly prepared from one or more of Al, SiO2, CNTs and GNFs. The CNTs and the GNFs are subjected to surface modification through gallic acid and rutin, and through combination with an in-situ reaction and a powder metallurgy technology, a CNTs independently enhanced aluminum-based composite, a GNFs independently enhanced aluminum-based composite and the CNTs and GNFs mixing enhanced aluminum-based composite with an Al / Si alloy as a matrix are prepared. The results show that 1, among the three composites, the 1% CNTs enhanced composite has the most excellent mechanical properties as well as the highest compactness, hardness and tensile strength; and 2, strengthening mechanisms of the CNTs enhanced aluminum-based composite mainly include the thermal expansion coefficient mismatch enhancement, Orowan enhancement and load transfer enhancement. The invention further discloses a preparation method of the aluminum-based composite. According to the method, the process is simple, production is easy, and broad application prospects are achieved.
Owner:SOUTHWEST JIAOTONG UNIV
High content troxerutin medicine and its preparing method
InactiveCN1554353AControl reaction endpointGuaranteed medicinal indicatorsOrganic active ingredientsBlood disorderActive matterRutin
The present invention discloses a troxerutin medicine with content of active matter 3', 4', 7-trihydroxy rutin over 90%. The active matter has molecular expression of C33H42O19 and molecular weight of 742.68. The preparation process includes the reaction stage comprising hydroxyethylation reaction, hot filtering and concentration; and the refining stage comprising heating, cooling, filtering and drying. The preparation process has high yield, low cost, simple and fast operation and high product quality, and is suitable for preparation of different medicine preparation forms.
Owner:SICHUAN XIELI PHARM CO LTD
Quercetin-3-O-acyl ester and preparation method thereof
InactiveCN102659735AEnhanced inhibitory effectOrganic active ingredientsOrganic chemistryRutinHydrolysis
The invention relates to quercetin-3-O-acyl ester and a preparation method thereof and belongs to the technical field of pharmaceutical chemistry. The preparation method comprises the following steps: taking cheap rutin as a starting raw material and preparing a quercetin-3-O-acyl ester compound through benzylation, hydrolysis under the acidic conditions, esterification, catalytic hydrogenolysis and other reactions. The method has the characteristics of good selectivity, mild reaction condition, high yield, low cost, simplicity and convenience in operation, easiness in industrial production and the like. In addition, the inhibitory effect of the obtained quercetin-3-O-acyl ester on human esophageal squamous carcinoma cells EC9706, human prostatic cancer cells PC-3 and human gastric cancer cells MGC-803 is remarkably superior to that of quercetin; and the quercetin-3-O-acyl ester can be used in the field of foods and medicines and is possible to develop into a new candidate drug for treating tumor.
Owner:ZHENGZHOU UNIV
Extractive of Taxus chinensis var.mairei leaves and preparation method
InactiveCN101716197AImprove microcirculationReduce myocardial oxygen consumptionConiferophyta medical ingredientsCardiovascular disorderDiseaseSolvent
The invention discloses an extractive of Taxus chinensis var.mairei leaves and a preparation method. The extractive is a straw yellow powder. The powder contains sciadopitysin the weight content of which is 65-70 percent; the sciadopitysin contains the following five components: 3-O-rutin-quercetol, 3-O-rutin-campherol, 3-O-rutin-myricetin, 7-O-glucose-campherol and 7-O-glucose-quercetol, and the total weight content of the five components in the sciadopitysin is 40-60 percent. The extractive is prepared by the preparation method comprising the steps of baking, crushing and screening, immersing into an alcohol dissolvant, ultrasonically extracting while stirring, decompressing and concentrating an extracting solution to remove alcohol, extracting with chloroform and degreasing, water phase concentrating and drying by taking fresh Taxus chinensis var.mairei leaves as raw materials. The extractive of Taxus chinensis var.mairei leaves has the functions of improving heat microcirculation, resisting arrhythmia, lowering myocardial oxygen consumption and the like and having the therapeutic and health-care function on diseases of cardiovascular system; and the preparation method has low energy consumption, short extracting time, few impurities and higher extraction efficiency.
Owner:宁波泰康红豆杉生物工程有限公司
Buckwheat starch syrup, method for preparing the same, and foods containing the same
InactiveUS6083539APromotes Nutritional BalanceGood for healthDough treatmentWort preparationPolygonum fagopyrumRutin
The present invention relates to a buckwheat starch syrup prepared by liquefying, saccharisfying, and proteolyzing starch from buckwheat flour, a method for preparing the buckwheat starch syrup, and various foods containing the same. The buckwheat starch syrup of the present invention contains various amino acids and minerals, as well as rutin which is effective in preventing arteriosclerosis, and hence it is healthy and excellent in nutritive balance. Thus, the buckwheat starch syrup of the present invention can be suitably used in various foods.
Owner:SAKUMA SEIKA
Action of ferulic acid on enhancing drug effect of some medicaments and purpose thereof
InactiveCN101721400AOrganic active ingredientsPharmaceutical non-active ingredientsCatharanthineChemical reaction
The invention relates to an action of ferulic acid on enhancing the drug effect of some medicaments and a purpose thereof, wherein the medicaments mainly comprise alkaloid medicaments including matrine, kushenin, sophocarpine, hyoscyamine, narceine, hanfangchin A, jamaicin, morphine, codeine, evodiamine, strychnine, catharanthine, vincristine, taxol, verticine, peimine, peiminine, ephedrine, pseudoephedrine, wilfordine, triptolide, tripdiolide and the like, and flavonoid medicaments including puerarin, ginsenoside, ginsengenin, mangiferin, scutelloside, alkannin, meletin, rutin, hesperidin, daidzin, soybean isoflavone, daidzein, carthamin, catechin and the like. The ferulic acid and the medicaments can form a compound or a medicament compound, or the ferulic acid and the medicaments can generate a chemical reaction (including salification, esterification, amidation, ketonization, etherification and the like), and / or the ferulic acid and the medicaments can generate a synergistic effect and an additive effect.
Owner:QINGDAO QIYUAN BIO TECH CO LTD
An electrochemical method for the simultaneous determination of rutin and quercetin based on a graphene-modified electrode
ActiveCN102288669AHigh catalytic activityHigh sensitivityMaterial electrochemical variablesBudDifferential pulse voltammetry
The invention discloses an electrochemical method based on a graphene-modified electrode for simultaneous determination of rutin and quercetin. The graphene-modified electrode is used as a working electrode, and cyclic voltammetry and differential pulse voltammetry are adopted for simultaneous determination of the rutin and the quercetin. Since grapheme is used as a modifying material for the electrode, electrochemical separation of two Chinese flavonoids, the rutin and the quercetin can be achieved on the modified electrode, and the contents of the rutin and the quercetin in sophora flower bud can be determined simultaneously through direct electrochemical determination.
Owner:QINGDAO UNIV
Inhibitors and Enhancers of Uridine Diphosphate-Glucuronosyltransferase 2B (UGT2B)
ActiveUS20090074708A1Increase heightReduced activityBiocideHydroxy compound active ingredientsPolyethylene glycolEriodictyol
A UGT2B inhibitor capable of increasing the bio-availability of a drug, is a compound in a free base or a pharmaceutically acceptable salt form that is selected from the group consisting of: capillarisin, isorhamnetin, β-naphthoflavone, α-naphthoflavone, hesperetin, terpineol, (+)-limonene, β-myrcene, swertiamarin, eriodictyol, cineole, apigenin, baicalin, ursolic acid, isovitexin, lauryl alcohol, puerarin, trans-cinnamaldehyde, 3-phenylpropyl acetate, isoliquritigenin, paeoniflorin, gallic acid, genistein, glycyrrhizin, protocatechuic acid, ethyl myristate, umbelliferone, PEG (Polyethylene glycol) 400, PEG 2000, PEG 4000, Tween 20, Tween 60, Tween 80, BRIJ® 58, BRIJ® 76, Pluronic® F68, Pluronic® F127, and a combination thereof. A UGT2B enhancer capable of enhancing a clearance rate of morphine-like analgesic agents, is a compound in a free base or a pharmaceutically acceptable salt form that is selected from the group consisting of: nordihydroguaiaretic acid, wogonin, trans-cinnamic acid, baicalein, quercetin, daidzein, oleanolic acid, homoorientin, hesperetin, narigin, neohesperidin, (+)-epicatechin, hesperidin, liquiritin, eriodictyol, formononetin, quercitrin, genkwanin, kaempferol, isoquercitrin, (+)-catechin, naringenin, daidzin, (−)-epicatechin, luteolin-7-glucoside, ergosterol, rutin, luteolin, ethyl myristate, apigenin, 3-phenylpropyl acetate, umbelliferone, glycyrrhizin, protocatechuic acid, poncirin, isovitexin, 6-gingerol, cineole, genistein, trans-cinnamaldehyde, and a combination thereof.
Owner:NAT DEFENSE MEDICAL CENT
Buckwheat malt seedling dish and production method thereof
InactiveCN101606483APromote absorptionImprove immunityFruit and vegetables preservationAgriculture gas emission reductionPolygonum fagopyrumAdditive ingredient
The invention discloses a buckwheat sprout seedling dish and a preparation method thereof, belonging to the field of foods. The preparation method of the buckwheat sprout seedling dish comprises the steps of seed selection, sterilization, seed soaking, sowing, sprouting, harvesting and the like, and the water content of the obtained buckwheat sprout seedling dish is 80% to 90%. In the invention, the buckwheat sprout seedling dish made by buckwheat after sprouting has the savory taste of buckwheat sprouts and is rich in flavonoid compounds, such as rutin and the like, and 18 kinds of amino acids necessary to a human body simultaneously, the mineral content of the buckwheat sprout seedling dish is higher than that of common buckwheat kernels, the activity of nutritional ingredients is reinforced, and the nutritional ingredients are easy for the human body to absorb; by eating the buckwheat sprout seedling dish frequently, the immunity of the human body can be enhanced, and the health of the human body is strengthened.
Owner:SHANGHAI INST OF TECH
Carbon nanotube surface molecularly imprinted polymer as well as preparation method and application thereof
ActiveCN103965418AUniform graft densityHigh selectivityMaterial electrochemical variablesCross-linkRutin
The invention discloses a carbon nanotube surface molecularly imprinted polymer as well as a preparation method and application thereof. The preparation method comprises the following steps: taking carboxylated multi-walled carbon nanotubes, synthesizing silicon dioxide-coated multi-walled carbon nanotubes by a sol-gel method; modifying the silicon dioxide-coated multi-walled carbon nanotubes by using a silane coupling agent to obtain alkenylated multi-walled carbon nanotubes; mixing the alkenylated multi-walled carbon nanotubes, Rutin and acrylamide under the protection of inert gas, and performing radical polymerization under the existence of an initiator and a cross-linking agent to prepare the carbon nanotube surface molecularly imprinted polymer. An electrochemical sensor manufactured from the carbon nanotube surface molecularly imprinted polymer has the characteristics of good conductivity, high selectivity, fast response, high sensitivity and the like to the Rutin and can quickly and effectively detect Rutin content of a sample.
Owner:JIAXING UNIV
Method for preparing quercetin and rhamnose by using flos sophora
InactiveCN102952108AOvercoming pollutionOvercome energy consumptionOrganic chemistryMicroorganism based processesFlosResource saving
The present invention belongs to the field of plant extraction, and specifically relates to a method for preparing quercetin by adopting flos sophora and producing rhamnose by using the quercetin preparation waste liquid. The technical problem solved by the method is to provide a completely new process for producing quercetin and rhamnose. The method specifically comprises the following steps: A, taking a proper amount of flos sophora, crushing, and adopting saturated and clarified lime water to extract rutin; B, adopting the rutin extracted in the step A to carry out hydrolysis to prepare quercetin; C, carrying out fermentation on the waste liquid from the step B to prepare a rhamnose crude product; and D, adopting methanol to separate glucose in the rhamnose crude product in the step C to prepare the rhamnose fine product. The method has characteristics of high yield, low cost, simple process, low pollution and low energy consumption, wherein the by-product rhamnose is produced so as to achieve a resource saving purpose.
Owner:CHANGSHA FUFANG PHARMA TECH CO LTD
Various grains chewing slice and preparation method thereof
The invention discloses miscellaneous grain chewable tablet which belongs to the technical field of agricultural product deep processing, and a preparation method thereof. The raw materials of the miscellaneous grain chewable tablet are oat, tartary buckwheat, pumpkin powder and auxiliary materials. The better preparation scope of the raw materials by the weigh portion is as follows: 20 percent to 35 percent of oat, 10 percent to 30 percent of tartary buckwheat, 10 percent to 30 percent of pumpkin powder and 5 percent to 60 percent of auxiliary materials. The preparation method comprises the following steps: (1) the oat and the tartary buckwheat are baked and ground; (2) the ground raw materials are mixed with the pumpkin powder and the auxiliary materials to prepare soft materials and particles; (3) the granulated raw materials are dried; (4)the dried raw material particles are pressed into finished products. The chewable tablet prepared by the invention has appropriate hardness, good taste, unique flavor, stable product quality, rich rutin, phaseomannite and Beta-hyskon, low heat, high nutrition, and can prevent diabetes, high blood pressure, etc. to some degree.
Owner:CHINA AGRI UNIV
Preparation method of buckwheat bread premixing powder
InactiveCN101390528AFood safetyImprove immunityBakery productsFood preparationPolygonum fagopyrumFreeze-drying
The invention discloses a preparation method of buckwheat bread ready-mixed powder containing buckwheat bran dietary fiber and rutin, comprising the following steps: a. bran defatting; b. smashing; c. dietary fiber extracting; d. dry packing; e. rutin extracting; f. separating and purifying; g. vacuum-concentrating; h. quick-freezing; i. vacuum freeze-drying; j. packaging; and k. ready-mixed powder preparing. Compared with other ready-mixed powders, the ready-mixed powder prepared by the invention is added with the active nutrient extract of buckwheat, and the bread made thereof is safe to consume and has buckwheat dietary fiber and rutin; the long-term consumption of the bread can help to improve body immunity and enhance human health.
Owner:SHANGHAI INST OF TECH
Method for suppressing fading of tar colorant, and fading-suppressed tar colorant-containing composition
InactiveUS20060051472A1Improve light fastnessSuppressing fadingFruit and vegetables preservationFood preparationChemical compoundTar
The present invention provides a method of suppressing fading of a tar colorant. More specifically, the present invention provides a method of suppressing a tar colorant fading phenomenon that occurs specifically in compositions containing (a) the tar colorant, and (b) at least one of reducing sugars, ascorbic acid compounds, or metals. This method can be attained by mixing (c) at least one selected from the group consisting of isoquercitrin, enzymatically modified isoquercitrin, rutin, enzymatically modified rutin, Chinese bayberry extract, and rosemary extract into such a composition, thus making the component (a), the component (b) and the component (c) coexist. The present invention further provides a composition for which fading of a tar colorant is suppressed using the above method, more specifically a composition containing at least one of reducing sugars, ascorbic acid compounds, or metals in addition to the tar colorant.
Owner:SAN EI GEN F F I
Extraction, purification and conversion of flavonoids from plant biomass
InactiveCN1685053AEffective biotransformationOrganic active ingredientsCosmetic preparationsRutinOrganic chemistry
Owner:加拿大农业部
Novel method for extracting rutin from pagodatree flower bud
InactiveCN103435667APromote dissolutionImprove solubilitySugar derivativesSugar derivatives preparationSolubilityDistilled water
The invention discloses a novel method for extracting rutin from pagodatree flower bud, and specifically relates to a method combining an ultramicro powder technology and continuous countercurrent ultrasound. The method comprises the following steps: after adding alkali liquor into superfine-grinded pagodatree flower bud, filtering to obtain leach liquor after continuous countercurrent ultrasonic extraction; repeatedly extracting the filter residue twice; combining the filtrate; adjusting the PH and carrying out acid precipitation; standing; filtering to obtain a rutin coarse extract; adding methanol to fully dissolve the rutin coarse extract; then, adding hot distilled water to stir; naturally cooling till rutin is recrystallized and separated out; repeatedly crystallizing twice; and then filtering and drying the crystals finally obtained to obtain high purity rutin. According to the novel method provided by the invention, least solvent is used to realize the maximum solubility, so that the novel method is high in extraction rate, short in extraction time and low in extraction cost, and is suitable for industrial production.
Owner:NANJING TONGZE AGRI SCI & TECH
Extraction, purification and conversion of flavonoids from plant biomass
InactiveUS20060099690A1Reduce manufacturing costSatisfy preferencesBiocideCosmetic preparationsXanthonoidCompound (substance)
A process for preparing a rutin-enriched composition from plant biomass comprises extraction with an aqueous solution, and precipitation. An enzyme preparation, such as naringinase, is used for the transformation of rutin to higher value compositions containing increased proportions of isoquercitrin and quercetin.
Owner:HER MAJESTY THE QUEEN & RIGHT OF CANADA
Preparation method of buckwheat tea
InactiveCN1478405AEfficient killingAvoid churnTea substituesFood preparationPolygonum fagopyrumAdditive ingredient
Owner:王永强
Method for preparing film coating antistaling agent for Rosa roxburghii and low-temperature fresh-keeping matching method thereof
InactiveCN101438734ANon-perishableGood colorFruits/vegetable preservation by coatingSucroseTitratable acid
The invention discloses a preparation method for a film coating antistaling agent for rosa roxburghii tratt, and a matching method for low-temperature fresh keeping. The antistaling agent is prepared by using the following raw materials: coating agent sodium alginate, agar, tamarind seed gum, guargum, surface acting agent, i.e., sucrose fatty acid ester, preservative agent, i.e., calcium propionate, ethylene inhibitor, 1-MCP, gene revulsant, i.e., diethyl aminoethyl hexanoate and water; the coating agent and the surface active agent are respectively heated with water to dissolve and then mixed, then the preservative agent, the ethylene inhibitor and the gene revulsant are added in, finally, the water with determined capacity is added and then evenly stirred while the mixture is still hot,so as to obtain the antistaling agent. The antistaling agent is put in the vessel when in use, then the dried fruits of the rosa roxburghii tratt are poured into the antistaling agent, dipped and coated, and then aired, and are stored in a cold storage warehouse with a temperature of 0 DEG C to 1 DEG C and a relative humidity of 60 percent to 70 percent. The rosa roxburghii tratt after being treated by the antistaling agent is not easy to be rotten, the content of the Vc, the SOD and the rutin is reduced little with the content of the titrated acidity, the fresh-keeping time reaches for 4 months to 6 months, and the antistaling agent facilitates storage and processing of the rosa roxburghii tratt and also improves the economic value of the rosa roxburghii tratt.
Owner:GUIZHOU UNIV +1
Method for preparing novel seasoning tea
The invention discloses a method for preparing novel seasoning tea, and belongs to the field of health-care functional tea drinks. The novel seasoning tea comprises the following raw materials: a tartary buckwheat semi-finished product, green tea and dried jasmine flowers in a ratio of 100:(31-40):(1-10). The method comprises the following steps of: mixing the raw materials, baking, stir-frying, extracting fragrance repeatedly at variable temperature, and fusing the fragrance of tartary buckwheat, the green tea and the dried jasmine flowers, so that the fragrance of the tartary buckwheat, thegreen tea and the jasmine flowers is shown and is blended mutually to form the unique fragrance of the green tea, the tartary buckwheat and the jasmine. In the method, the seasoning tea is processed by utilizing the natural and health-care value of the green tea and the tartary buckwheat scientifically and a unique process according to the principle of the homology of medicines and food; and the green tea tartary buckwheat mixed health drink is rich in biological active ingredients such as rutin (V P) and the like, and is particularly suitable for preventing and treating diseases such as hypertension, hyperlipaemia, hyperglycemia, cardiovascular diseases and the like, so the novel seasoning tea is a natural drink which integrates ornamental, drinking and health care properties.
Owner:四川蒙顶山味独珍茶业有限公司
Wine of wild buckwheat and preparation method
A wild buckwheat wine for softening blood vessel and delaying sanility is prepared from wild buckwheat through choosing raw materials, proportionally mixing, distilling, cooling, adding yeast, and fermenting in cellar.
Owner:刘道文
Production process for extracting high-purity birutan from flos sophora
ActiveCN101423538AImprove solubilityThe chance of mutual aggregation is reducedSugar derivativesSugar derivatives preparationSolubilityFlos
The invention discloses a production process for extracting high-purity rutin from bud of Chinese scholartree. The process mainly comprises the following steps: selecting clean bud of Chinese scholartree, crushing the bud of Chinese scholartree, percolating the bud of Chinese scholartree through a dissolvent, carrying out the acid precipitation of the filtrate, and drying the filtrate, so as to obtain crude rutin; dissolving the crude rutin in saturated ferric ammonium citrate solution, putting the solution in water bath at a temperature between 40 and 50 DEG C; and stirring the solution for 30 minutes, filtrating, cooling down the solution through standing, then carrying out acid precipitation and suction filtration, cleaning the filter residue through purified water to reach neutrality, and drying the filter residue, so as to obtain the refined rutin. The production process has the advantages that ferric ammonium citrate is taken as the flux of rutin, thereby polymerizing the ferric ammonium citrate molecule and the ortho-phenolic hydroxyl in the rutin molecule, ensuring that the planar structure of the rutin molecule is polymerized into a heterocycle-shaped complex steric structure, reducing the mutual polymerization of the rutin molecules, and greatly improving the solubility of the rutin in water; the production process not only has high yield and purity, but also has simple technology and low manufacturing cost.
Owner:GUANGXI CHANFANG PHARMACEUTICAL CO LTD
Silver-thorn tea beverage and preparation method thereof
InactiveCN101317615AGuaranteed functionPrevent diseasePre-extraction tea treatmentCardiovascular disorderBlack teaBilobalides
The invention provides a gingko-buckthorn tea beverage, which is prepared by lotus leaf, hawkthorn, buckthorn extract, gingko leaf extract, black tea, pu'er tea and water. According to the ginkgolides A (C20H24O9), B (C20H24910) and C (C20H24O11) and bilobalide (C15H18O8), the content of the gingko leaf in the gingko-buckthorn tea is not less than 4.0mg; according to Isorhamnetin (C16H12O7), the content of the buckthorn and the gingko leaf is not less than 0.025mg; according to anhydrous rutin, the content of total flavonoid is not less than 0.13g. The invention also discloses a preparation method for the gingko-buckthorn tea beverage. The gingko-buckthorn tea beverage of the invention has the functions of blood-activating, stasis-dissolving, blood pressure decreasing and blood lipid decreasing, which is applicable for the prevention and health care of middle-aged and aged people, people with high blood lipid and high blood pressure and fat people.
Owner:SHANGHAI UNIV OF T C M
Use of bioflavanoid or polyphenolic substance for treating parkinson's disease
The invention discloses application of bioflavonoids or polyphenol compounds to preventing and treating Parkinson diseases. The bioflavonoids or polyphenol compounds can be selected from kaempferol-3-O-rutinoside, dehydrated carthamin yellow B, 6-hydroxyl kaempferol-3, 6-dioxygen glucoside, (2S)-4', 5-dihydroxyl-6, 7-dioxygen flavonone glucoside, rutin, quercetin, vanillina or isovanillin. Through large amount of experiments, the bioflavonoids or polyphenol compounds have activity of interacting with protein DJ-1 related to the Parkinson diseases. Through further experiments, the bioflavonoids or polyphenol compounds have pharmaceutical activities for resisting oxidative stress, preventing apoptosis of PC12 cells or primary nerve cells induced by the oxidative stress, inhibiting active oxygen generation in cells, improving activity of tyrosine hydroxylase, and the like, and can be used for preventing or treating the Parkinson diseases.
Owner:PEKING UNIV
Flavonoid solubilizing agent and method of solubilizing flavonoid
InactiveUS20060153936A1Versatile and easily operableEasy to operateBiocideSugar derivativesSolubilityIsoflavones
A flavonoid solubilization agent capable of highly solubilizing flavonoids such as isoflavone, baicalin, rutin and naringin whose solubility is generally low; and a method of effecting the above solubilization. Flavonoids can be solubilized by causing a flavonoid and soybean saponin and / or malonyl isoflavone glycoside to be co-present in an aqueous medium.
Owner:FUJI OIL CO LTD
Rutin-zein-sodium caseinate composite nanoparticles and preparation method thereof
InactiveCN106727428AEasy to embedImprove antioxidant capacityOrganic active ingredientsAntinoxious agentsPrillSpectrum analyzer
The invention provides rutin-zein-sodium caseinate composite nanoparticles and a preparation method thereof. The rutin-zein-sodium caseinate composite nanoparticles are prepared by taking rutin as an antioxidant, taking zein as a carrier and taking sodium caseinate as a stabilizer through an anti-solvent method. Instruments such as a laser particle analyzer, a Fourier transform infrared spectrum analyzer and a scanning electron microscope (SEM) are adopted for analyzing the representational structure of the nanoparticles, and the yield, the controlled-release rate and oxygen resistance are measured. As proved by a result, the composite nanoparticles have a very good embedding effect on the rutin, have small particle sizes, and are uniformly distributed in solutions; as indicated by an SEM picture, the composite nanoparticles are spherical, and the particle sizes are uniform in distribution; as indicated by the analysis of the Fourier transform infrared spectrum analyzer, hydroxyl radicals in nanoparticle molecules are increased; moreover, the prepared nanoparticles have a certain controlled-release proportion and high oxygen resistance.
Owner:QINGDAO AGRI UNIV
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