The invention discloses a method for extracting high-purity
hesperetin from immature bitter orange, which comprises the following steps: 1. pulverizing immature bitter orange, extracting with
alcohol solvent under
reflux three times, filtering, merging the three filtrates, and concentrating; 2. adding inorganic acid into the concentrated solution for
hydrolysis, naturally cooling to
room temperature, filtering, washing the filter residues, and centrifugalizing to obtain a crude
hesperetin product; and 3. dissolving the crude
hesperetin product in
ethanol, adding
activated carbon to decolorize under
reflux, filtering, concentrating, crystallizing, filtering, and
drying the filtered
solid matter to obtain the hesperetin crystals of which the
mass purity is not lower than 95%.By using the immature bitter orange as the
raw material for extraction,
hydrolysis and refinement, compared with the traditional technique of extracting hesperetin from
hesperidin, the invention reduces the intermediate links, lowers the production loss, enhances the production yield of hesperetin, lowers the production cost, and eliminates the
hesperidin refinement,
drying and other links in the original production process, thereby greatly shortening the
production cycle.