193 results about "Daidzein" patented technology

This invention provides a composition comprising a daidzein-containing substrate and a strain of micro-organism capable of metabolizing daidzein to equol as essential ingredients. This composition is effective in the prevention and alleviation of unidentified clinical syndrome inclusive of menopausal syndrome in middle-aged to elderly woman for which no effective means of prevention or alleviation has heretofore been available.

The invention relates to essence, in particular to flavoring essence used for tobacco. The flavoring essence is formed by mixing the following raw material components in percentage by weight: 1 to 3 percent of 10 percent vanillin, 2 to 4 percent of 10 percent damascenone, 2 to 4 percent of 10 percent ethyl maltol, 5 to 8 percent of stachyurus extract, 2 to 4 percent of Peru concrete, 1 to 3 percent of five-flavor ketone, 0.5 to 2 percent of 10 percent furaneol, 1 to 3 percent of 10 percent oak chip extract, 0.5 to 2 percent of 10 percent cassia leaf oil, 0.5 to 2 percent of elecampane extract, 1 to 3 percent of 10 percent clove bud oil, 2 to 4 percent of Xianning orange osmanthus extract, 1 to 3 percent of 1 percent valerian oil, 1.5 to 3 percent of trigonella tincture, 0.5 to 2 percent of 10 percent geranium oil, 15 to 20 percent of white hyacinth bean tincture, 1 to 3 percent of 10 percent acetic ether, 5 to 8 percent of lonicera confusa extract, 1 to 3 percent of ribes burejeuse extract, 8 to 51.5 percent of 70 percent ethanol, and 1 to 3 percent of daidzein. The flavoring essence used for the tobacco overcomes the defects that the prior cigarette has burr feeling at the throat and astringent feeling at the oral cavity, and has quite obvious effect of improving the comfort of the cigarette.

The invention discloses feed for parental breeding ducks and a preparation method thereof and belongs to the field of animal feeds. The feed is prepared by adopting corn, wheat, fine rice bran, fermented soybean meal, corn protein powder, corn distiller, peanut meal, hydrolyzed feather meal, meat meal, stone powder, soybean oil, calcium hydrophosphate, 70% lysine, methionine, salt and premix as raw materials, crushing, mixing and granulating. The premix is prepared from choline chloride, baking soda, tryptophan, phytase, neutral protease, a compound enzyme preparation, dietary daidzein, lysozyme, a microecological preparation, carotene, a trace element premixing agent, a vitamin premixing agent and corn germ meal. The feed disclosed by the invention has the advantages that the matching ratio is scientific, the nutrition is comprehensive, the preparation method is simple, the production cost is low, the digestion utilization rate and the laying rate of the parental breeding ducks for the feed are increased, the high-peak period of laying is long, the elimination rate and the broken-egg rate are low, and simultaneously the contents of N, P and heavy metals in feces are reduced and the ecological environment of a water body is improved.

The invention relates to a feed formula for improving bone and eggshell quality of laying hen and a preparation method of the feed formula. The feed formula is prepared from the following raw materials in parts by weight: 550-600 parts of corn, 200-250 parts of soya bean meal, 85-95 parts of full-fat rice bran, 8-12 parts of soya-bean oil, 2-5 parts of edible salt, 80-120 parts of shell powder, 5-10 parts of calcium hydro-phosphate, 1-1.2 parts of choline chloride, 2-4 parts of amino acid, 1-3 parts of sodium bicarbonate, 0.2-0.8 part of an antioxidant, 0.2-0.5 part of a ginkgo leaf extract, 0.2-0.5 part of an enzymic preparation, 0.2-0.5 part of daidzein, 0.2-0.5 part of ploysavone, 0.1-0.3 part of selenium yeast, 2-3 parts of trace elements and 2-3 parts of vitamin. The feed formula disclosed by the invention has the advantages of enhancing the absorption of nutrient substances, enhancing the immunity of a hen body, increasing the egg production rate of the laying hen, improving the bone and eggshell quality and egg quality of old laying hens and prolonging the peak egg production season.

The invention discloses a method for preparing drug residue free feed for feeding live pigs. The method comprises the steps of: preparing 1 part of bacterial strain, 0.1 part of lower polyxylose and 0.2 part of daidzein by mass, adding 10 parts of water, stirring for 30-45 minutes, and preserving the water temperature at 20-35 DEG C; preparing 100 parts of feed and 20 parts of corn steep liquor by mass and adding into a cone type stirrer together, loading into a plastic bag with a reducing valve after stirring to be uniform, stacking at a warehouse for fermentation, unpacking the plastic bag after 72 hours, pouring out, drying, and packaging. In the invention, the raw materials need no strict sterilization and can be directly inoculated and cultured, inhalation consumption is very low without exceeding 1.0 percent generally, the heat radiated during fermentation is lower, the operation is easy to control, the production process is simplified, the production cost is reduced, the equipment investment is low, a feed factory can be used for carrying out granulation production without increased cost on a feeding farm, thereby being easy to popularize.

The invention provides a genistein-3'-sodium sulfonate, dimethylation daidzein-3'-sodium sulfonate and their preparing process comprising the steps of, charging reactants genistein or dismethylation daidzein into the dissolvent, charging sulphonating agent, subjecting the reactant and sulphonating agent to chemical reaction, separating the mixture by means of the conventional methods and purifying. The invention also provides a medicament and composition for treating cardiovascular and cerebrovascular diseases.

A dropping pill of soybean aglycon is prepared from soybean aglycon, polyethanediol as carrier dimethyl silica oil as coolant, surfactant and stearic acid through proportionally mixing soybean aglycon with fused polyethanediol, surfactant and stearic acid, stirring, and dropping in the dimethyl silica oil.

The invention discloses a health- caring wine containing good effective element. The wine with alcohol degree being 15- 75 (V / V %) comprises maltol, borneo camphor, cedrol, dimethyl trisulfide, dimethyl bisulfide, ligustrazine, daidzein, crust and puerarin, which not only changes wine color, but aslo does not influence waste, no toxic action. The health- care wine can improve bloos circulation, reduce blood pressure, reduce blood fat and promote circulation of qi and relieve pain, resist tumor and cause head pain after excessive drink.

The invention discloses engineering bacteria for producing S-equol. The engineering bacteria for producing S-equol are obtained by cloning L-DDRC, L-DZNR, L-DHDR and L-THDR genes from Lactococcus sp. 20-92 to escherichia coli BL21 (D3) and transforming. The engineering bacteria for producing S-equol provided by the invention are simple in fermentation condition, convenient to use, stable in system, and wide in application; the engineering bacteria for producing S-equol have the ability of transforming daidzein in BHI and LB culture media into S-equol whether under an anaerobic condition or an aerobic condition, and have the ability of transforming bean pulp in BHI and LB into S-equol. Release of daidzein of the bean pulp in the BHI is facilitated.

The invention discloses an oral preparation composition of a self-emulsified daidzein and a preparation method. The composition is made up of 0.5 through 5 percent daidzein, 30 through 60 percent emulsifier, 10 through 40 percent auxiliary emulsifier and 10 through 30 percent grease. The preparation method is as follows: the daidzein is dissolved in cosurfactant under the temperature ranging from 10 DEG C to 80 DEG C, after being cooled, the daidzein is added with an oil phase and the emulsifier then is stirred uniformly. The invention has the advantages of simple operation and easy preservation. The oral preparation composition of the self-emulsified daidzein in the invention can absorb the water in human gastrointestinal tract after being taken orally, with uniform grain diameter ranging from 10nm to 100nm.

The invention discloses a bean yoghourt fermenting agent with processing suitability as well as a preparation method and application thereof, and belongs to the field of bioengineering. The preparation method of the bean yoghourt fermenting agent with the processing suitability comprises the following steps: an exogenous microbial population is added into reconstituted milk, and the exogenous microbial population, the reconstituted milk and Kefir grains are mixed and fermented; after multi-generation domestication, a Kefir fermenting agent is reformed, so that the microbial population structure of the reformed Kefir fermenting agent is changed, and the reformed Kefir fermenting agent is used for fermenting bean milk so as to produce bean yoghourt; soybean isoflavone can be biologically converted, so that concentration of genistein and daidzein in the bean yoghourt is improved; the reformed Kefir grains are adopted to prepare the fermenting agent so as to ferment the beam milk, so that the Kefir bean yoghourt is smooth in taste and rich in nutrition, absorption and utilization of vegetable protein for a human body can be improved, and probiotics in the bean yoghourt is increased; the soybean isoflavone can be biologically converted, so that the concentration of the genistein and the daidzein in the bean yoghourt is improved, and the bioavailability of the soybean isoflavone is improved.

The invention relates to a daidzein derivative which has the following chemical formula: in the chemical formula, at least one of R1 and R2 is carbonyl containing 1 to 3 carbon atoms, R3 and R4 are selected from alkyl, amino, amino derivative, ureido, guanidyl and amino acid containing 1 to 4 N atoms. The derivative adopts the daidzein as raw material, firstly carries out acylation with acylate reagent so as to obtain a midbody, and then obtains target product by reaction of midbody with R3 and / or R4. The derivative changes the polarity of the daidzein and space structure, improves water solubility, also improves permeability function of the cellular membrane and effectively improves the oral bioavailability thereof.

A dripping pill of daidzein is prepared from daidzein and the medicinal auxiliary including high-molecular carrier, cosolvent and matrix. The condensing agent for shaping dripping pill is dimethyl silica oil.

The invention belongs to the field of food fermentation, and proposes a fermented yellow serofluid beverage rich in aglycone isoflavones. The beverage comprises a tofu yellow serofluid fermentation product, wherein the content of aglycone isoflavones in the fermented yellow serofluid beverage is 10-200 [mu]g*mL<-1>, and the aglycone isoflavones include daidzein and genistein. The invention also provides a preparation method of the fermented yellow serofluid beverage. The beneficial technical effects of the invention are as follows: probiotics with high isoflavone conversion efficiency are screened, and the glycoside isoflavones in the fermentation product are converted to the aglycon isoflavones to the greatest extent. The bioavailability of soy isoflavones in the yellow serofluid is improved, and flavoring agents and juice are added after the probiotic fermentation is completed so as not only to obtain the aglycone isoflavones to the greatest extent, but also to increase the rich nutrients in the juice. The fruit fragrance and the bean fragrance complement each other, and the beverage is mild and gentle in mouth fell and balanced and uniform in nutrients. The method provides a newmodel for developing functional beverages by using yellow serofluid.

The invention discloses wild-radix-puerariae health care nutrient rice and a preparation method of the wild-radix-puerariae health care nutrient rice. The wild-radix-puerariae health care nutrient rice is characterized in that the wild-radix-puerariae health care nutrient rice is prepared in the way that 30 to 70 percent rice meal and 70 to 30 percent of wild radix puerariae powder are mixed and made into dough through water addition, the dough is extruded into rice grain shapes by a granulating machine, and the microwave drying is carried out. The wild radix puerariae is added into the rice, the effects of changing non-grains into grains and changing coarse grains into refined grains are reached, and the important meaning is realized on ensuring the grain safety. The nutrient rice can provide calories, in addition, a higher health care effect is realized, and the nutrient rice is rich in isoflavone, puerarin, radix puerariae wood powder glycoside, daidzein and the like, also contains various kinds of amino acids and trace elements and has good health care effects of reducing the blood fat, enhancing heart vitality and preventing and curing cardiovascular and cerebrovascular diseases. The color luster of the nutrient rice is light brown and bright, the boiled rice is fine and soft, the mouth feeling is good, and the nutrient rice is particularly suitable for being eaten by user groups with hypoimmunity and cardiovascular diseases. Through the development of the wild-radix-puerariae health care nutrient rice, the bran-new food is provided for people, and the positive meaning on developing the mountainous area economy and overcoming poverty and achieving prosperity by farmers is also realized.

A medical daidzein composition suitable to prepare solution-type medicine (such as injection) with high water solubility and no toxic by-effect is prepared from daidzein, cyclodextrin and water-soluble auxiliaries. Its preparing process is also disclosed.

The invention discloses an application method of beta-glucosidase in bean milk. Specifically, the bean milk is inoculated with cultured lactobacillus plantarum, and an isoflavone glucoside compound in the bean milk is directly converted into an isoflavone aglycon compound through the beta-glucosidase produced by the lactobacillus plantarum in the fermentation process of the bean milk, so that the biological availability of the bean milk is improved. After the application method disclosed by the invention is used, the highest activity of the beta-glucosidase is 9.24U / mL, the pH of the beta-glucosidase is 4.12, the content of lactic acid is 92.45mM, the content of acetic acid is 10.01mM, the content of soybean aglycone is 9.06mg / L and is increased by 1.9 times, and the content of genistein is 34.14mg / L and increased by 4.0 times. According to the application method disclosed by the invention, the biological availability of the bean milk is effectively improved, and the digestion and the absorption of human bodies are facilitated; the flavor of the bean milk is adjusted through the lactic acid and the acetic acid; and besides, through the addition of probiotics namely the lactobacillus plantarum, the health of the intestinal tracts of the human bodies is promoted.

Disclosed is microbe with the capacity to convert 50% or more of daidzein to equol in 24 hours, a food or medical composition that contains said microbe, a method of manufacturing equol using said microbe, and a nucleic acid fragment that can specifically detect said microbe.

This invention provides a composition comprising a daidzein-containing substrate and a strain of micro-organism capable of metabolizing daidzein to equol as essential ingredients. This composition is effective in the prevention and alleviation of unidentified clinical syndrome inclusive of menopausal syndrome in middle-aged to elderly women for which no effective means of prevention or alleviation has heretofore been available.

The invention relates to kudzuvine root vermicelli, which comprises the following main components in part by weight: 50 to 51 parts of kudzuvine root powder, 30 to 38 parts of sweet potato powder and 20 to 11 parts of corn flour. A ratio of the mixture of the kudzuvine root powder, the sweet potato powder and the corn flour to water is 100: 78-86. A process for producing the kudzuvine root vermicelli comprises the following steps of preparation, stirring, molding, freezing, airing, dishing, shaping, secondary airing and packaging, and a finished product. The kudzuvine root vermicelli has the following advantages that: the main components comprise amino acid, selenium, zinc, manganese, germanium, puerarin, daidzein and isoflavone which are needed by a human body; the puerarin enjoys the fame as 'Asian ginseng' and 'long life powder', can enhance human immunity and the constitution of the human body, prevent ageing and prolong the life of the human body if the puerarin is frequently taken, also can prevent hypertensions and coronary diseases and has the effects of producing refreshing effect to the mind, neutralizing the effect of alcoholic drinks and expelling toxin; and the kudzuvine root vermicelli has simple process, low production cost, good product quality, pure and delicate taste and unique flavor, and is good for both children and adults.

An extract of kudzu used for preparing the medicines to treat the climacteric syndrome of woman, osteoporosis, and cardiovascular and cerebrovascular diseases is disclosed. Its preparing process is also disclosed.

The invention discloses a method for separating a genistein monomer from a daidzein monomer. The method comprises a preparation process of a gold nanotubule membrane, a modification process of the gold nanotubule membrane, a preparation process of an aluminum chelate and a membrane separation process. The method helps realize high-efficiency selective separation of the genistein monomer and the daidzein monomer by utilizing mechanism that the gold nanotubule membrane is modified with p-aminothiophenol so that the membrane is positively charged at a lower pH value, and plays electrostatic repulsion on positively charged genistein and aluminum chelate without repulsion on daidzein which can not form a chelate with the aluminum. The method has the advantages of simple operation, low energy consumption and high efficiency of separation, no pollution, high purity of the monomers separated, industrialized implementation and the like. The method is of great theoretical significance for further research on pharmacological action, mechanism, popularization and application of genistein and daidzein.

An isoflavone sulfonates derivative and the synthesis process are characterized in that the chemical structural general formula is that R1 is OR3 and OCOR4, R2 is aromatic sulfonic acid ester group, and R3 and R4 is C1-C2 alkyl. The compound ester solubility of the invention is greatly improved compared with soybean aglycone.

The invention discloses a feed for relieving heat stress of laying hens, and relates to the field of feed processing. The feed comprises the following raw materials: a corn powder, rice bran, soybean meal, peanut cakes, fish meal, bone meal, table salt, vitamins, a mint extract, a dried tangerine or orange peel extract, a rhizoma coptidis extract, tea polyphenols, citric acid, beta-carotene, organic selenium, zinc gluconate, copper sulfate, daidzein and astragalus polysaccharide. The feed is rationally prepared according to physiological change characteristics of the heat stress of the laying hens, can enhance the ability of the laying hens to resist the heat stress, and has obvious effect, so that the egg yield of the laying hens under a high temperature condition is not affected.

The invention relates to a method for preparing high-purity puerarin and daidzein at the same time. The method comprises the following steps of: mixing and extracting crushed kudzu root and ethanol in a feed liquid ratio of 1:6 to 1:10; filtering the obtained mixture, and performing vacuum concentration on the filtrate until the filtrate is dried to obtain a kudzu root extract; re-dissolving the kudzu root extract by using an ethanol solution with appropriate concentration, and then refluxing, hydrolyzing and extracting the mixture for a certain period of time by adding a hydrochloric acid solution and chloroform; standing and cooling; separating the chloroform; performing vacuum concentration; performing recrystallization on the concentrate by adopting the ethanol solution to obtain daidzein crystals; adding water to dilute acid hydrolysate; placing the mixture for 48 to 72 hours to separate out puerarin coarse crystals; and performing recrystallization on the puerarin coarse crystals by using acetic acid-methanol to obtain a puerarin product. By adopting the method, the puerarin and the daidzein in the kudzu root are extracted and separated at the same time, so that the utilization value of the kudzu root is improved, and a traditional Chinese medicinal material resource is fully used. According to the method, hydrolysis and extraction are finished at the same time, so that operation process steps are reduced, the usage amount of the solvents is reduced, the production cost is low, and the yield is high.

The invention relates to a tobacco feeding essence, in particular to a tobacco feeding essence for replenishing bean-flavor note, which is formed by mixing the following raw materials in part by weight: 16-18 parts of black vanilla bean derivatives, 1.5-2 parts of cocoa extractives, 6-8 parts of almond derivatives, 2-3 parts of white hyacinth bean extractives, 2-2.5 parts of daidzein, 5-7 parts of fig extracts, 2.5-3 parts of plum extracts, 10-12 parts of Tsaoko Amomum fruit derivatives, 4-5 parts of balsamroot extractives, 1-1.5 parts of graecum extracts and 38-50 parts of propylene glycol water solutions. The tobacco feeding essence obviously replenishes the bean-flavor note and has comfortable and natural fragrance and good sweet feel, obviously enhances the concentration of the fragrance in tobaccos and also improves fragrance quality and smoking comfortableness when improving the concentration of the fragrance in tobaccos.

The present invention relates to the field of improving nutritional content and more particularly the isoflavone content in plants. The invention provides a process for increasing the content of the isoflavone daidzein in selected plants, novel plants produced by this process and products derivable therefrom.

The invention discloses a medicine for treating osteoporosis, which is prepared mainly from total daidzein, total epimedium flavones, and added crystalline cellulose,sodium carboxymethylstarch through the steps of palletizing, drying, and granulating.