1287results about How to "Has inhibitory effect" patented technology

The invention relates to a titanium-based multi-metal oxide catalyst for removing diesel engine NOx by NH3-SCR in a wide temperature window, belonging to the technical field of exhaust contaminant control on diesel engine tail gas. The catalyst uses nano TiO2 as a carrier, uses metal oxides V2O5, CeO2, MnO2 and Fe2O3 as main active components, and uses WO3 and MoO3 as catalyst promoter components, wherein the contents of the main active component in the catalyst respectively are as follows in percentage by weight: 48-84% of TiO2, 1-3% of V2O5, 5-15% of MnO2, 1-5% of CeO2, 1-5% of Fe2O3, 3-9% of WO3 and 5-15% of MoO3. The preparation process of the catalyst comprises the following steps: pre-activating the TiO2; and determining charge numbers of the metal oxide main active components and the catalyst promoters, and charging the metal oxide main active components and the catalyst promoters. By replacing high poisonous V oxides with Ce, Mn and Fe oxides, the invention reduces environmental hazard of the catalyst, greatly improves the low-temperature activation and the high-temperature selectivity, and effectively decreases NOx in the wide temperature window of 100-550 DEG C. The catalyst has high sulfur poisoning resistance and water poisoning resistance, and is suitable for high-sulfur diesel fuel and urban road conditions in China.

The invention belongs to the technical field of ultrasonic cavitation detection and signal analysis, and relates to a method and a device for separating and detecting focused ultrasonic cavitation signals. An ultrasonic transducer of a device emits cavitation detecting signals in a pulse-inversion mode, and another ultrasonic transducer receives acoustic signals diffused by ultrasonic cavitation and movement of microbubbles; a transducer of another device generates cavitation signals in the pulse-inversion mode; for each cavitation detecting experiment, the detection method extracts background signals when the cavitation does not happen, respectively calculates power spectrums of the acquired cavitation acoustic signals and the background signals, calculates the subtracted power spectrum estimation and phase position estimation, and converts the power spectrum estimation and the phase position estimation into time domain signals to filter noise of a system; and an ICA method separates target signals such as broadband noise component, subharmonic and the like in cavitation acoustic signals from other signal components and extracts characteristic parameters of the cavitation acoustic signals. The detection method has high sensitivity and can perform quantitative analysis.

The invention discloses a quinazoline derivative and a pharmaceutically acceptable salt thereof showed in a formula I, or their enantiomer, diastereoisomer, tautomer, racemate, solvate, metabolic precursor or prodrug. The invention also discloses a preparation method, an intermediate, a composition and an application. The quinazoline derivative has good antineoplastic activity.

The invention relates to a ferulic acid shown in a general formula (I) and the application of derivatives thereof to pesticides. When used as novel anti-phytoviral agents, the derivatives can well inhibit tobacco mosaic viruses, pepper viruses, tomato viruses, sweet potato viruses, potato viruses, melon viruses, maize dwarf mosaic viruses and the like, and effectively prevent and control the virus diseases of various crops such as tobacco, peppers, tomatoes, melons, grains, vegetables, beans and the like, and are particularly suitable for preventing and controlling tobacco mosaic. Meanings of each group are shown in specifications.

The invention provides a triple-enzyme hydrolysis preparation method of anti-tumor polypeptides of spirulina. The method comprises the following steps: preparing a solution having a concentration of 5 percent from spirulina powder with ultrapure water; repeatedly freezing and thawing, homogenizing and performing ultrasonic treatment, centrifuging to obtain supernate, freezing and drying for later use; adding the prepared protein fluid into pepsin for enzyme hydrolysis, controlling the pH value, adding trypsin for enzyme hydrolysis, adding chymotrypsin for enzyme hydrolysis, controlling the pH value, deactivating enzyme, cooling, and centrifuging to obtain supernate; sequentially filtering with ultrafiltration membranes having molecular weight cut-off of 10KD, 5KD and 3KD respectively to obtain three kinds of spirulina protein enzymatic hydrolysates; carrying out sephadex G15 column chromatography on 0-3K of enzymatic hydrolysate, eluting with water, and collecting four polypeptide ingredients, namely anti-tumor polypeptides of spirulina. The obtained spirulina polypeptide and monopeptide ingredients can be used for establishing a theoretical basis for development and utilization of anti-tumor medicines and health foods.

The invention discloses a preparation method of a medical ozone ointment dressing plaster. The preparation method comprises the specific steps: (1) continuously introducing medical ozone into vegetable oil, and stopping introduction of the ozone when the content of the ozone reaches 80g/L-120g/L, thus obtaining ozone oil; (2) mixing the ozone oil with vaseline, paraffin and a traditional-Chinese-medicine extract, heating for melting, then adding peppermint oil, and stirring uniformly to prepare ozone ointment; (3) soaking medical dressing in the ozone ointment, melted by heating, for 10-20 minutes to obtain ozone oil dressing; (4) carrying out sterilizing treatment on the ozone oil dressing. The preparation method of the medical ozone ointment dressing plaster disclosed by the invention has the advantages that the medical ozone ointment dressing plaster has no any chemical additives and no toxic and side effects, can prevent adherence of wounds when in use, has the effects of inhibiting and killing bacteria, promoting wound healing, moisturizing and protecting wound surfaces and the like, has better clinical application value and is convenient to use and carry.

The invention discloses preparation methods of a sustained-release microcapsule and a sustained-release composite membrane for inhibiting the monilinia fructicola. The preparation method of the sustained-release microcapsule comprises the following steps: the chitosan and the berberine are weighed, the mass ratio between the chitosan and the berberine is 9-11:0.22-0.28, the acetate solution is added, then the chitosan and the berberine are sufficiently swelled to obtain berberine-chitosan solution after stirring for dissolving, standing and air bubble removal, and the berberine-chitosan solution is added in the soybean oil containing span 80, stirred at the constant temperature of 40-50 DEG C and then emulsified for 28-32 min to form a W/O system; the glutaraldehyde solution is added for stirring for 2.5-3.5 hours, and the centrifuging is carried out so that the microcapsule is fully settled; and the preparation liquid on the upper layer is obliquely taken, the obtained microcapsule is washed with petroleum ether for 3-5 times and then dried for 23-25 hours under the vacuum at the temperature of 48-52 DEG C. The invention also provides the preparation method for the sustained-release composite membrane for inhibiting the monilinia fructicola. Both the microcapsule and the composite membrane have the sustained-release effects and have no toxic side effect to the environment and the plants since the berberine is a native compound.

The invention relates to a water-based anti-bacterial floor wax. The floor wax has main components and weight ratio as follows: 10 percent to 70 percent of water-based polymer with 30 percent to 50 percent of solid content, 0 percent to 5 percent of alkaline soluble resin with 20 percent to 40 percent of solid content, 2 percent to 12 percent of plasticizing and film-forming auxiliary agent, 0.01 percent to 2 percent of defoamer, 1 percent to 10 percent of water-based wax emulsion, 0 percent to 1 percent of wetting flow agent, 0.01 percent to 5 percent of antibacterial agent, and 0 percent to 50 percent of deionized water. The invention has suppression functions for a plurality of common bacteria with the reasonable choice of composite antimicrobial products; the invention has the advantages of high antibacterial efficiency, long-time medicinal effect, good decorative effect, safety and environmentally protective performance.

The invention discloses a lignum naucleae leaf extract which is characterized in that the extract is obtained by using one of the following methods: (1) the lignum naucleae leaf extract is obtained by water extraction and impurity removal of traditional Chinese medicine lignum naucleae leaves; (2) the lignum naucleae leaf extract is obtained by alcohol extraction and impurity removal of the traditional Chinese medicine lignum naucleae leaves; (3) the lignum naucleae leaf extract is obtained by lipophilic organic solvent extraction and impurity removal of the traditional Chinese medicine lignum naucleae leaves, and the lipophilic organic solvent includes but not limited by n-butyl alcohol or ethyl acetate. The invention further discloses a preparation method of the lignum naucleae leaf extract, a preparation and a new purpose. The lignum naucleae leaf extract of the invention has exact effects of clearing heat and removing toxin. The extraction process of the invention is simple and reasonable, which can obtain the effective parts. The invention opens up a precedent of obtaining the lignum naucleae leaf extract from the lignum naucleae leaves to be used for the drugs for clearing heat and removing toxin, which can not only ease the shortage of raw materials, but is also conductive to the sustainable and rational development, utilization and protection of lignum naucleae resources.

The invention relates to a special compound feed for litopenaeus vannamei. The feed is composed of following components in percentage by weight: 18 to 24% of steam fish meal, 17 to 22% of soybean meal, 15 to 24% of peanut meal, 2 to 4% of spray-dried animal blood cells, 2 to 4% of squid paste, 2 to5% of yeast extract, 20 to 25% of flour, 2 to 3% of fish oil, 1 to 2% of soybean oil, 1.0% of shrimp multi-vitamin, 2.0% of shrimp multi-mineral and 1.0% of litopenaeus vannamei special feed addictive, and the sum of the components mentioned above is 100%. The nutrition composite of the compound feed is obtained from numerous tests according to the nutrition need of litopenaeus vannamei, can fully satisfy the nutrition need of litopenaeus vannamei, improves the immunity and disease preventing ability of litopenaeus vannamei, and promotes the healthy growth of litopenaeus vannamei.

The present invention provides a recombinant PAI-1 inhibitor, which is an uPA hydrolase domain with S195A mutation or a PAI-1 hydrolase domain with S195A mutation, and has PAI-1 binding force. The present invention further provides a composition containing the inhibitor, and uses of the composition in preparation of treatment drugs and PAI-1 detection reagents. According to the present invention, the uPA or tPA hydrolase domain is modified to optimize the binding force with the PAI-1 so as to construct the recombinant PAI-1 inhibitor, wherein the recombinant PAI-1 inhibitor contains the least S195A point mutant.

The invention provides a dual-enzyme hydrolysis preparation method of anti-tumor polypeptides of spirulina. The method comprises the following steps: preparing spirulina holoprotein with pure water by means of repeated freezing and thawing, homogenizing and ultrasonic treatment; preparing spirulina polypeptides by means of an alkaline protease Alcalase 2.4 and papain dual-enzyme hydrolysis method; separating and purifying by utilizing an ultrafiltration membrane to acquire spirulina polypeptides having molecular weight ranges of 0-3K, 3-5K, 5-10K and more than 10K. The obtained spirulina polypeptide and monopeptide ingredients can be used for establishing a theoretical basis for development and utilization of anti-tumor medicines and health foods.

The invention relates to a preparation method of epothilones B. In particularly, the invention provides a technique method to prepare epothilones B through adopting 100 to 500 liters fermentor to ferment and to separate epothilones B in large scale. The invention also relates to the preparation and application of epothilones B in preparation of gleevec resistance chronic myeloid leukemia treatment drug.

A health-care food for preventing and treating atherosclerosis, hypercholesterolemia, hyperlipemia, hypertension, coronary heart disease, angina pectoris, tumor, etc, and balancing the functions of organs is prepared from 10 Chinese-medicinal materials including anemarrhena rhizome, ginger, wolfberry fruit, yam, etc.