111 results about "Normal flora" patented technology

The present disclosure provides for characterization of normal flora and identifying biomarkers in the gut of healthy, neruotypical subjects. Aspect of the disclosure provide for the characterization of the gut microbiome in ADS subjects, characterized by reduced richness and significant loss of the ‘Prevotella-like enterotype’ compared to neurotypical subjects. The relative abundance of genera Prevotella, Coprococcus, Prevotellaceae and Veillonellaceae are significantly lower in autistic children than in neurotypical children. Further, Prevotella, is one of the three main classifiers for the human enterotypes, along with Bacteroides and Ruminococcus. These three core genera are among main contributors in the principle component analysis. ‘Prevotella-like enterotype’ was absent in the autistic group, while neurotypical samples showed an even distribution among the three enterotypes. The present disclosure provides for an understanding the association between gut microbiota, health, and disease states, and provides for potential diagnostic and therapeutic targets.

The invention discloses a culture feed for piglets, which mainly comprises corn, rice, full-cream puffed soybean, fermented bean pulp, peeled bean pulp, fish meal and the like. Yeast cell extract is added to enhance the immunity of piglets, and compound enzyme preparations and probiotics are used instead of high copper and high zinc, thereby lowering the environmental pollution, enhancing the digestion and absorption of the feed, and maintaining normal flora of the intestinal tract. Full organic trace elements are used instead of inorganic trace elements, thereby lowering the oxidization of inorganic salts on the feed and organisms. The invention also discloses a preparation method of the culture feed, which effectively reserves beneficial ingredients and discards harmful ingredients through the granulation process, thereby effectively reserving the nutritive value of the feed.

This invention is a probiotic composition using the delivery mode of a rectal suppository for the treatment and relief of symptoms of urogenital infections including prostatitis. This invention is unique in both mode of delivery and in enabling the treatment of such urogenital infections as prostatitis. The present invention discloses compositions, methodologies, and delivery mode for the utilization of probiotic organisms in therapeutic compositions for treatment and relief from the symptoms of urogenital infections by maintaining and restoring normal flora in humans. The composition includes one or more bacteria selected from the genus Lactobacillus. More specifically, the invention relates to the utilization of one or more species or strains of Lactobacillus producing bacteria for the control of urinary tract bacteria and pathogens, including antibiotic-resistant urinary tract pathogens, and their associated diseases by both a reduction in the rate of colonization of the infection and pathogens. The method for treatment and relief from symptoms includes administration via a rectal suppository with a safe and effective amount of the composition. The delivery mode for administering the probiotic is via a rectal suppository. The delivery through the rectum provides an optimum method of transmission of the treatment.

The invention relates to the technical field of daily care products, in particular to a washing-free foam type female bactericidal solution and a preparation method thereof. The washing-free foam type female bactericidal solution is prepared from natural plant saponins, a bactericidal odor removing agent, a nourishing and moisturizing agent, a plant anti-allergic anti-itching agent, a solvent, lactic acid, citric acid, sodium citrate, a solubilizer and ethyl alcohol. The washing-free foam type female bactericidal solution is a foam type care solution capable of being internally used and can have a larger surface area to make contact with skin; meanwhile, foam is not prone to overflow, and long-acting sterilization protection is achieved. The bactericidal solution can reduce damage to female physiological environment to the maximum extent and protect mucosa and skin of private parts from being injured. In addition, the bactericidal solution has killing and inhibiting effects on harmful germs in vaginas, has a protection effect on beneficial bacteria and maintains balance of normal flora at the female private parts.

The invention relates to the medicines for gynecopathy, in particular to gel for adjusting microecology in vaginas of women, solving the problem that the traditional gynecological lotion kills probiotics while killing pathogens, thus causing vaginal flora imbalance and low immunity and further causing repeated vaginitis. The gel comprises the following components according to mass concentration: 0.5-2% of Carbomer, 0.1-1% of soy peptide, 0.001-0.01% of isoflavone, 0.5-3.5% of carotene and 0.3-3% of tea tree oil. The gel achieves the aim of suppressing pathogens by promoting lactobacillus proliferation. At present, the products in the market aim to kill the bacteria but finally disturb normal flora balance. The gel increases the absolute number of the lactobacillus, a predominant bacterium, simultaneously reduces the pathogens, maintains the balance of microecology in vaginas and improves vaginal cleanliness and the immunity of the vagina mucosa, thus achieving the aims of preventing gynecological vagina inflammation and reducing the reoccurrence rate of gynecological vaginitis. Besides, the formula of the gel is pure vegetable protein, thus being safer than other bacteriostats and bactericides.

The invention discloses special EM (Effective Microorganisms) bacteria powder for aquaculture, as well as a preparation method and application of the special EM (Effective Microorganisms) bacteria powder. Bran, corn flour, amino acid powder and the like, which are used as dry matter fillers, are mixed with brown sugar, glucose and the like to obtain a mixture; the mixture is subjected to sealing fermentation at 25-37 DEG C for about 10 days by lactic acid bacteria, bacillus licheniformis and bacillus coagulans, so that fermented materials are prepared; then the prepared fermented materials are dried and crushed and are mixed with bacillus subtilis to obtain a final product. The EM bacteria powder can be directly scattered in a water body to inhibit pathogenic microorganisms through mass propagation of probiotics, decompose harmful substances in the water body, promote the growth of normal floras and beneficial algae in a cultivation ecosystem and keep the ecological balance of the aquaculture water body. The method is adopted to prepare the EM bacteria powder, the fermentation period is short, the process is simple, the equipment investment is low, the materials are convenient to obtain, and the method is easy to implement and is suitable for industrial production and self-production of households.

The invention relates to a non-ionic surface active agent vesicle capable of restoring skin micro-ecology. The vesicle is characterized by comprising the following components by weight percent: 0.1% to 40% of a non-ionic surface active agent, 0.1% to 40% of an active composition for restoring skin micro-ecology, and 1.0% to 60% of water soluble alcohol. The invention also discloses a preparation method of the vesicle. The method comprises the following steps: A, mixing the active composition for restoring skin micro-ecology and the water soluble alcohol, heating to 70 to 80 DEG C, and stirring until the mixture is completely dissolved; B, preparing an non-ionic surface active agent composition; C, mixing the substance obtained from step A and the substance obtained from step B, adding a proper amount of deionized water, performing thermal insulation for 10 minutes at the temperature of 70 to 80 DEG C, cooling, and adding a proper amount of an anti-corrosive agent. The vesicle and the preparation method have the advantages that three types of active substances, namely coconut freeze-dried powder, burdock extract and flaxseed extract, can be simultaneously coated; the normal flora micro-ecology of skin can be restored; the stability of active substances is improved, and the transdermal effect is good.

The invention provides konjac fermented food and beverage and a preparation method thereof, and relates to the technical field of food and beverage processing. The preparation method comprises the following steps: preparing konjac fluid, preparing primary seed fluid, preparing secondary seed fluid, inoculating and fermenting, and preparing a finished product. The konjac fermented food and beverage have the advantages that konjac glucomannan (KGM) is high molecular polysaccharide, has an effect of promoting growth of bifidobacterium of human intestinal tracts, so that the structure of intestinal flora can be effectively improved. Lactic acid bacteria are normal flora of a human body, and the probiotics represented by the lactic acid bacteria is necessary to the human body, and are beneficial bacteria with critical physiological functions, so that animal growth can be promoted, normal flora of gastrointestinal tracts can be regulated, the micro-ecological balance can be maintained, the gastrointestinal tract functions can be improved, body immunity is improved. Carbon sourced substances are required when lactic acid bacteria ferment, starch is the carbon source for growth and metabolism of microorganisms, and 10 to 30 percent of the konjac is starch, so that the konjac can be effectively used as the carbon sourced substance in lactic acid bacteria fermentation. Therefore, the content of effective components of konjac is taken, and the process of lactic acid bacteria fermentation is introduced, so that the konjac fermented food and beverage can be a perfect combination of the two advantages technologically.

The invention discloses a functional toothpaste preparation for preventing and treating periodontitis. The functional toothpaste preparation comprises the following components in parts by weight: 5-25 parts of an abrasive, 1-5 parts of a humectant, 1-3 parts of a surface active agent, 2-10 parts of thickener, 0-0.5 part of a preservative, 1-5 parts of an active material, 0-2 parts of a pigment, 0-2 parts of essence and distilled water added to 100 parts. According to the functional toothpaste preparation for preventing and treating periodontitis, functional materials of carboxymethyl chitosan, carboxymethyl chitin and the like with injured tissue repair promoting action are adopted; bacteria adhesion is prevented; the active materials of antibacterial plant polypeptide and the like for oral periodontitis pathogenic bacteria growth are inhibited; the preparation does not contain a pharmaceutical ingredient; imbalance of normal flora in the oral cavity is avoided; compared with traditional toothpaste, the functional toothpaste preparation has the effects of preventing and treating a periodontal disease; compared with the medicine for treating periodontitis, the functional toothpaste preparation has the characteristics of being mild, safe, lasting, effective and the like, and is an excellent oral heath product; the medicine resistance is not easy to generate; and tooth stone formation is relieved.

The invention provides a beautifying facial cleanser and a production method thereof and belongs to the field of skin protecting and face washing products. The beautifying facial cleanser can be used for solving the problems that an acne-removing and anti-aging facial cleanser is easy to result in skin allergies, is too irritant to skin and contains a chemical bacteriostatic agent and normal flora on skin can be destroyed in the prior art. The beautifying facial cleanser comprises the following components in volume fraction: 6-10 parts of egg white, 10-12 parts of 30-50-degree white wine, 5-8 parts of Chinese herbal medicinal extracting solution, 0.2-0.5 part of vitamin E, 3-5 parts of honey, 1-2 parts of rice vinegar, 2-4 parts of a surfactant, 1-6 parts of a moisturizer and 45-55 parts of deionized water. The beautifying facial cleanser provided by the invention has the beautifying effects of whitening, removing freckles, reducing wrinkles, resisting ageing, enhancing skin elasticity, moistening skin, removing acnes and fading acne marks on the surface of the skin; and meanwhile, pure plants are adopted, and no chemical substance irritant to the skin is contained, so that the beautifying facial cleanser provided by the invention is non-irritant to the skin, is difficult to result in the skin allergies, hardly results in skin vicious circle after being used for a long time and can not promote secretion of grease.

The invention relates to a preparation method for infant composite protein nutrition powder, which includes steps of (1) weighing lactalbumin powder, xanthan gum, calcium lactate, oligosaccharide and homogenized lecithin according to weight percent and mixing; (2) adding isoflavones and uniformly mixing; (3) sterilizing, aseptic packaging, subpackaging, inspecting and warehousing finished product. The added oligosaccharide of the present invention can adjust normal flora in body gastrointestinal tract, generates special enzyme serious, increases absorption and reabsorption of isoflavones, is rich in nutrients such as vitamin and trace elements, is especially favourable to growth of infant and is a nutrient milk capable of substituting breast milk. The method is easy, raw material source is wide and cost is low.

The invention relates to a shrimp fertile-benefiting growth promoter, which is prepared from the following components in part by weight: 65 parts of starwort root, 70 parts of astragalus, 65 parts of rehmannia root, 40 parts of codonopsis pilosula, 60 parts of common cnidium fruit, 35 parts of dwarf lilyturf tuber, 35 parts of manyflower solomonseal rhizome, 65 parts of hairyvein agrimonia herb and bud, 80 parts of figwort root and 30 parts of tea leaf. The shrimp fertile-benefiting growth promoter fully exerts the synergy of all the components by the selection of the medicinal components and reasonable compatibility, and has the following advantages of keeping balance of normal flora, obviously inhibiting the growth of harmful bacteria and viruses, regulating immune functions of bodies, promoting intestinal peristalsis, improving the survival rate of shrimps, promoting the reproduction of beneficial microorganisms, improving the activity of metabolic enzymes and cell vitality, accelerating nutrition absorption, improving food intake conditions and improving health levels of the bodies. An appropriate number of shrimp fertile-benefiting growth promoters are added into a feed, the speed at which the shrimps are fed is doubled, the feed coefficient is obviously reduced, and the protein efficiency is obviously improved, so that the breeding cycle is greatly shortened.

The invention provides a grapefruit mouth spray and a preparation method thereof. The grapefruit mouth-spray comprises a disinfectant, a sweetener, a cool aromatizer and other additives, and is characterized in that the disinfectant is an extract of the natural grapefruit. Traditionally used chemical disinfectants are cast off and plant disinfection is adopted in the invention, which can achieve the effects of disinfecting the infectious bacteria in the oral cavity so as to eliminate halitosis and refresh the oral odor, without harming the normal flora. The grapefruit mouth sprayer has simple preparation method, no toxic and side effects, good effects of sterilization and good taste.

The invention relates to the field of biological medicine, in particular to a vaginal infection prevention immune globulin compound preservative. The effective active components of the compound preservative are composed of immune globulin IgY of yolk, chitosan and triclosan. The vaginal infection prevention immune globulin compound preservative is used for preparing medicine for treating the vaginitis, is capable of restraining bacteria and candida in the vagina and not damaging the ecological balance of a normal flora in the vagina, prevents vagina dryness, is free of side effects and is suitable for preventing and treating the early-stage vaginitis.

The invention provides application of a medicine containing catechin shown in formula (I) or catechin polymorphs to preparation of antibacterial medicines. Through experiment research, the catechin is wide in antibacterial spectrum and has exact inhibiting effect on various pathogenic microorganisms such as staphylococcus aureus, escherichia coli, candida albicans, pseudomonas aeruginosa and hemolytic streptococcus; meanwhile, the catechin has good selectivity and has no irritation to normal flora and vagina mucosa, thereby being promising in application prospect on preparation of the antibacterial medicines. Formula (I).

The invention discloses a production technology of lactobacillus fermented soybean meal. The production technology comprises the following steps: (1) lactobacillus strain activation; (2) lactobacillus strain liquid culture; (3) lactobacillus strain culture in a serum bottle; and (4) soybean meal fermentation. The production technology is simple and easy to understand; lactobacillus can promote animal growth, adjust gastrointestinal normal floras, and maintain microecological balance so as to improve gastrointestinal functions, a lactobacillus micro ecological preparation provides an efficient, harmless, non-polluting new choice for feed and animal husbandry and aquaculture industries, and by using of characteristics of the animal floras themselves and the relationship between soil and environment, the lactobacillus micro ecological preparation is used scientifically and rationally, so that largest ecological effects and economic benefits can be obtained.

The invention provides a technology for increasing the content of protein of gingko nuts by performing solid fermentation on the gingko nuts. The technology comprises the following steps of stir-frying, decladding, drying, smashing, and performing aerobiont solid fermentation and anaerobe solid fermentation. According to the technology, the gingko nuts are processed by adopting a biont solid fermentation technology, so that the toxicity of the gingko nuts is reduced greatly; the contents of total proteins and essential amino acid are increased; and nutritional ingredients of the gingko nuts are increased greatly. In addition, lactic acid bacteria used by the anaerobic fermentation are probiotics for a human body; a fermented product after the anaerobic fermentation contains a large number of lactic acid bacteria having effects of promoting the growth of the human body, adjusting gastrointestinal tract normal flora, maintaining the microecological balance and improving gastrointestinal tract functions accordingly; the food digestibility and a biological value are improved and increased; serum cholesterol is reduced; endotoxin is controlled; the growth of putrefying bacteria in an intestinal tract is inhibited; functions of the body such as the immunity are improved; and the bioavailability of the gingko nuts is improved greatly by the fermented product.

The invention discloses a water quality balance ferment for aquaculture and organic sewage treatment and a preparation method thereof. The water quality balance ferment comprises: 10-15% of sugarcane molasses, 0.5-2.0% of milt cake, 10-20% of starch; 0.6-1.5% of a photosynthetic bacteria seed solution, 0.6-1.5% of a Bacillus subtilis seed solution, 0.6-1.5% of a lactic acid bacteria seed solution, 0.6-1.5% of a yeast seed solution, 0.6-1.5% of a Gram positive actinomycete seed solution, 0.6-1.5% of a nitrosomonas seed solution, and 0.6-1.5% of a thiobacillus seed solution; and the balance purified water. The invention also relates to a preparation method and use method of the water quality balance ferment. The quality balance ferment prepared by the method provided by the invention can enhance the resistance of the aquatic products and accelerate growth rate, and after permeating water, can inhibit pathogenic microorganisms and harmful substances, adjust the culture ecological environment, increase the amount of dissolved oxygen in water, promote the activated growth of normal flora and beneficial algae in an aquaculture ecosystem, and keep the ecological balance of the aquaculture water.

The invention discloses a special food eaten by patients with gestational diabetes mellitus. The special food is prepared by taking various bagasse or resistant dextrin, probiotics, and a compound extract of affinal drug and diet, which can reduce blood glucose of patients with gestational diabetes mellitus, as primary raw materials, taking oligopeptide, wheat or rice flour, flaxseeds, a fatty powder and saccharomycetes as auxiliary materials and adding compound vitamins and compound mineral substances to refine. By means of a biorelease technology, the stability of postprandial blood sugar ofthe patients with gestational diabetes mellitus is ensured, and the damage of hypoglycemia is also avoided. Basic nutrients can be supplemented, the situation that the nutrients are imbalanced or exceeded is improved, secretion of insulin is affected by edible blood glucose reducing factors to protect the liver, tonify the kidney and build the body, and the blood glucose is controlled on the basis of not affecting the normal flora of the intestinal tract, so that the effect of addressing both symptoms and root causes is achieved. In addition, the invention also provides a preparation method of the special food eaten by patients with gestational diabetes mellitus. The special food prepared by the invention is suitable for patients with gestational diabetes mellitus to eat.

The invention discloses a preparation method of an active lactobacillus preparation containing hericium polysaccharides. The preparation method includes the steps of (1) preparing the hericium polysaccharides; (2) preparing an active lactobacillus powdered preparation; (3) preparing sea-buckthorn powder, apple peel powder and peanut coat powder; (4) preparing a finished product. Gastrointestinal tract system disease prevention and treatment functions of the hericium polysaccharides are made full use of, essence parts of hericium are extracted, a beneficial intestinal flora is led in through manual intervention by the technology of combined co-fermentation of various probiotics, probiotics beneficial to normal flora proliferation of a human body are added, material basis is provided for continuous proliferation of intestinal bacteria, the sea-buckthorn powder, the apple peel powder and the peanut coat powder are particularly added, and the active lactobacillus preparation has fine healthcare effects and no toxic and side effects.

An application of butanoic acid bacteria in preparation of candy. The invention relates to novel usage of butanoic acid bacteria in field of candy preparation, the butanoic acid bacteria candy has many actions when it is considered as a candy food and is eat for long time, such as maintaining the stability of normal bacteria in intestinal canal, maintaining the body in a state of good health, adjusting the imbalance of bacteria in intestinal canal, improving the action of micro-ecologic environment, playing a role of adjusting the intestine and defending infection, and the butanoic acid bacteria can adjust the normal creeping motion of intestine to achieving the action of softening stool, releasing or eliminating constipation, eliminating abdominal distention and adjusting, treating, preventing constipation, the butanoic acid bacteria candy can improve the immune function, inhibiting and rreleasing anaphylaxis, improving the role of the liver.

The invention discloses a manufacturing method for underpants. The method comprises the following steps: (1) preparing an underpants body; (2) preparing a crotch cloth at an inner side of a crotch; (3) preparing an anus paste crotch cloth; connecting the underpants body, the crotch cloth at the inner side of the crotch and the anus paste crotch cloth, which are respectively prepared in the steps (1)-(3), thereby obtaining the underpants. The underpants have the advantages of breathability, dryness, moisture absorption, high drying speed, anti-microbial and deodorizing properties, mite-proof and mold-proof properties, sanitary safety, physical anti-microbial effect, capability of maintaining normal flora and no side effect.

The invention relates to antibacterial and antiphlogistic health care mouth wash with honeysuckle flower as a main material. The health care mouth wash is prepared from the following raw materials: honeysuckle flower, radix astragali, leaf of bamboo, radix notoginseng, chrysanthemum flower, water, xylitol, peppermint and glycerine. The health care mouth wash has stronger inhibiting effects on various bacteria, viruses and the like, has the functions of maintaining normal floras in oral cavities, treating halitosis and preventing swelling and aching of gum, can not cause allergic reaction and can be used for effectively preventing oral ulcers.

The invention relates to the field of health care of foods, in particular to a preparation method for obtaining ferment capable of neutralizing the effect of alcoholic drinks through fermenting radixpuerariae juice. The preparation method comprises the following steps of by using radix puerariae as a raw material, adding amylase, performing steaming, gelatinization and liquefaction, controlling the inoculum concentration of lactobacillus plantarum FCJX 102 (lactobacillus plantarum FCJX 102), and at different fermentation temperatures and time, obtaining the ferment capable of neutralizing theeffect of alcoholic drinks, which is unique in flavor. The preparation method disclosed by the invention has the advantages that the ferment is rich in nutrient components and unique in flavor, and the defects that Chinese herbal medicines are bitter in mouth feel and pungent in smell originally are overcome; the normal floras of gastrointestinal tracts are regulated to a certain extent, microecological balance is maintained, the functions of the gastrointestinal tracts are improved, and the immunity of organisms is improved; the content of aldehyde dehydrogenase is high, and the ferment hasgood effects of neutralizing the effect of alcoholic drinks and protecting the liver; and the steps are simple, the operation is flexible, time and labor are saved, the quality guarantee period time is long, resource waste in processing and producing of enterprises is reduced to a great extent, and the market competitiveness of the enterprises is strengthened.

The invention relates to lactobacillus agilis and an application thereof and belongs to the technical field of microorganisms. The bacterial strain is a lactic acid bacterium which is separated from a normal microbial flora in intestinal tracts of a healthy pig. By means of Gram staining microscopy, physiological biochemical test and 16s-rRNA sequence analysis, the bacterial strain is identified to be a strain of lactobacillus agilis. Through growth curve drawing, gastrointestinal tract stress resistance environment test and in-vitro enteroadhesive test screening, the lactobacillus agilis strain shows the best biological characters when being compared with other lactic acid bacteria separated from the intestinal tract. The lactobacillus agilis can be applied as a feed additive in production of piglets when being completely cultured. The lactobacillus agilis can promote growth and increase utilization rate of the feed, can reduce diarrhea ratio, improve animal immunity level and improve disease resistance, can effective replace antibiotics in feed additives. The invention provides an excellent bacterial strain for probiotics, and has important significance of improving economic benefit in pig breeding and developing healthy breeding of pigs.

The invention relates to a female care solution and further relates to a preparation method of the female care solution. The female care solution is prepared from a propolis extract, collagen liquid, an aloe extract, a mint herb extract, a pectin solution, hyaluronic acid, sodium pyrrolidonecarboxylate, chlorobutanol preservative and the like. The female care solution does not contain a chemical bacteriostatic agent, is free of toxic and side effects, the active ingredient propolis has the inhibiting effect on harmful bacteria in the vagina and meanwhile has the protection effect on beneficial bacteria, and balance of normal flora of the vagina is kept. The female care solution is low in ethanol content and free of stimulatory effect and is stable.

The invention discloses a propolis medicine for restoring ecological balance of female genital care and a preparation method thereof, and relates to the technical field of traditional Chinese medicines. The propolis medicine is prepared from the following raw materials in parts by weight: 1-3 parts of gold foils, 3-8 parts of a saussurea involucrata extract, 5-10 parts of collagen peptide, 5-10 parts of propolis, 3-5 parts of radix sophorae flavescentis, 3-5 parts of cortex phellodendri, 1-3 parts of fructus kochiae, 1-3 parts of fructus cnidii, 5-10 parts of aloe, 3-5 parts of ethylparaben and 10-20 parts of purified water. According to the propolis medicine for restoring the ecological balance of the female genital care and the preparation method thereof, normal flora in the vagina can be maintained, the micro-ecological environment can be protected, harmful bacteria can be killed, beneficial flora can be protected, and the effects of sterilization and disinfection can be achieved, so that a very good prevention effect on gynecological diseases can be achieved.

The invention belongs to the field of formula foods with a special medical purpose and in particular relates to a full-nutrient formula food containing probiotic microcapsules and having the special medical purpose and a preparation method thereof. In a formula, a plurality of types of probiotics are combined with other necessary components of human bodies to prepare the full-nutrient formula food; when nutrients needed by every day are guaranteed, a normal flora structure in intestines of a patient is reconstructed through digested probiotics, normal physiological functions of the intestines are recovered and the immunity and self-healing capability of organisms are improved. Meanwhile, positioned release control of the probiotics is realized and the clinical curative effect is improved; a fluidized bed lateral spraying microcapsule preparation technology is applied so that the prepared probiotic microcapsules have room-temperature preservation and enteric soluble properties.

The invention discloses a feed additive for improving the growth performance of weaned piglets. The feed additive is prepared from D-aspartic acid, lactobacillus paracasei, lactobacillus delbrueckii subspecies bulgaricus, bifidobacterium adolescentis and soybean meal serving as a carrier. Preferably, the feed additive is prepared from the following components in parts by weight: 50 parts of the D-aspartic acid, 5 parts of the lactobacillus paracasei, 10 parts of the lactobacillus delbrueckii subspecies bulgaricus, 10 parts of the bifidobacterium adolescentis and 25 parts of the carrier soybeanmeal powder. The feed additive does not contain any antibiotic component, and has the advantages of no toxicity, no drug residue, no drug resistance, no pollution and the like. Besides, the feed additive contains three probiotics, and due to the unique physiological activity and biological functions of the three probiotics, the feed additive has the effects of improving immunity, maintaining normal flora balance of gastrointestinal tract, helping to generate adhesion resistance and the like.