37183 results about "Biological activation" patented technology

A combination medical device comprising a circular stapler instrument and one or more portions of preformed buttress material adapted to be stably positioned upon the staple cartridge and / or anvil components of the stapler prior or at the time of use. Positioned buttress material(s) are delivered to a tissue site where the circular stapler is actuated to connect previously severed tissue portions. The buttress material is retained and provides an improved seal between the joined tissue sections. The buttress material is made up of two regions, one of which serves primarily to secure the buttress material to the stapler prior to actuation, and one of which serves primarily to form the improved seal. The former region is severed and discarded upon activation of the circular stapler to form an anastomoses. Methods of use and preparation of the buttress material are also described.

An ultrasonic clamp coagulator assembly that is configured to permit selective cutting, coagulation and clamping of tissue during surgical procedures. An elongated portion of the instrument can be configured for endoscopic applications and has an outside diameter of less than 6 mm. The construction includes a clamping mechanism, including a clamp arm pivotally mounted at the distal portion of the instrument, which is specifically configured to create a desired level of tissue clamping forces, exceeding 4 pounds when the trigger is fully closed. The clamping mechanism includes a two-piece pad design and pad material that enables the higher tissue clamping forces and a force-limiting mechanism that effectively smooths out abusive tissue forces. The assembly also features hand activation configured to provide an ergonomical grip and operation for the surgeon. Hand switches are placed in the range of the natural swing of the surgeon's thumb, whether gripping the surgical instrument right-handed or left handed.

A linear surgical stapler adapted for applying a plurality of surgical fasteners to body tissue includes an anvil structure and a cartridge housing containing a plurality of surgical fasteners. The cartridge housing and anvil structure are relatively movable between a first spaced apart position and a second position in close approximation with one another. A firing mechanism is associated with the cartridge housing for ejecting the surgical fasteners from the cartridge housing to be driven against the anvil structure. A lockout mechanism interacts with the cartridge housing for selective activation and deactivation. The lockout mechanism includes a swing gate tab secured to the cartridge housing at a position adjacent a lockout lever, such that firing of the linear surgical stapler rotates the swing gate tab releasing the lockout lever for preventing further firing of the used cartridge housing.

A surgical fastener cartridge is provided and includes a cartridge body having a plurality of surgical fasteners operatively disposed therein. An actuation mechanism is housed within the cartridge body and includes a plurality of pushers operably associated with the plurality of surgical fasteners. The actuation mechanism includes a plurality of pivotably connected link assemblies. Each link assembly being pivotably engaged with a corresponding bottom surface associated with each the pushers and a corresponding top surface associated with an internal channel housing and operably coupled to one another. The actuation mechanism includes an activation structure configured to move each of the link assemblies and sequentially cause each of the link assemblies to move through a succession of motions within the cartridge body, such that the link assemblies cause the corresponding pusher to contact and, subsequently, sequentially eject the associated surgical fastener towards the depression in the anvil.

An ultrasonic clamp coagulator assembly that is configured to permit selective cutting, coagulation, and fine dissection required in fine and delicate surgical procedures. The assembly includes a clamping mechanism, including a clamp arm cam-mounted at the distal portion of the instrument, which is specifically configured to create a desired level of tissue clamping forces. The balanced blade provides a functional asymmetry for improved visibility at the blade tip and a multitude of edges and surfaces, designed to provide a multitude of tissue effects: clamped coagulation, clamped cutting, grasping, back-cutting, dissection, spot coagulation, tip penetration and tip scoring. The assembly also features hand activation configured to provide an ergonomical grip and operation for the surgeon. Hand switches are placed in the range of the natural axial motion of the user's index or middle fingers, whether gripping the surgical instrument right-handed or left handed.

A method of facilitating communications and collaboration of a group of plural remote participants comprises steps of receiving information over an information communications network from a first group participant; pushing, over the network to at least one other group participant, an access via an access channel; and allowing the other group participant to access at least some of the received information via said access channel in response to selective activation of the access channel by the other group participant.

A medical system for finding and displaying the location of electrodes within the body. The electrodes may be used to measure the voltage on the heart wall and display this as an activation map on a geometry representing the heart chamber.

An ultrasonic clamp coagulator assembly that is configured to permit selective cutting, coagulation and clamping of tissue during surgical procedures. An elongated portion of the instrument can be configured for endoscopic applications and has an outside diameter of less than 6 mm. The construction includes a clamping mechanism, including a clamp arm pivotally mounted at the distal portion of the instrument, which is specifically configured to create a desired level of tissue clamping forces, exceeding 4 pounds when the trigger is fully closed. The clamping mechanism includes a two-piece pad design and pad material that enables the higher tissue clamping forces and a force-limiting mechanism that effectively smooths out abusive tissue forces. The assembly also features hand activation configured to provide an ergonomical grip and operation for the surgeon. Hand switches are placed in the range of the natural swing of the surgeon's thumb, whether gripping the surgical instrument right-handed or left handed.

A touch screen computer executes an application. A method of operating the touch screen computer in response to a user is provided. A virtual input device is provided on the touch screen. The virtual input device comprises a plurality of virtual keys. It is detected that a user has touched the touch screen to nominally activate at least one virtual key, and a behavior of the user with respect to touch is determined. The determined behavior is processed and a predetermined characteristic is associated with the nominally-activated at least one virtual key. A reaction to the nominal activation is determined based at least in part on a result of processing the determined behavior.

A shape-memory device manufactured from shape memory material includes multiple activation temperatures. The multiple activation temperatures arise from either the heat treatment of the device during manufacturing, or by combining different elements with different activation temperatures. To manufacture a shape-memory device with multiple activation temperatures, it is formed into a first shape. A first portion of the shape-memory device is heated to a first temperature, and a second portion of the shape-memory device is heated to a second temperature. The shape-memory device is then worked into a second shape. Accordingly, the first portion has a first transition temperature, and the second portion has a second transition temperature. In use, the shape-memory device is placed into a desired position. Energy is applied such that the first portion, second portion, or both portions are transformed.

Chimeric T cell receptors (TCR) are provided that combine, in a single chimeric species, the intracellular domain of CD3 ζ-chain, a signaling region from a costimulatory protein such as CD28, and a binding element that specifically interacts with a selected target. When expressed, for example in T-lymphocytes from the individual to be treated for a condition associated with the selected target, a T cell immune response is stimulated in the individual to the target cells. The chimeric TCR's are able to provide both the activation and the co-stimulation signals from a single molecule to more effectively direct T-lymphocyte cytotoxicity against the selected target and T-lymphocyte proliferation.

Power is supplied to an information handling system chipset with a single voltage regulator having dual phases. A first phase of the voltage regulator provides power to a low power state power rail in an independent mode to support a low power state, such as a suspend or hibernate state. A second phase of the voltage regulator provides power to a run power state power rail in combination with the first phase by activation of a switch, such as a MOSFET load switch, that connects the low power state power rail and the run power state power rail. Voltage sensed from both power rails is applied to control voltage output so that the run power state power rail is maintained within more precise constraints than the low power state power rail.

A combination medical device comprising a circular stapler instrument (4) and one or more portions of preformed buttress material (16) adapted to be stably positioned upon the staple cartridge (12) and / or anvil (14) components of the stapler (4) prior or at the time of use. Positioned buttress material(s) (16) are delivered to a tissue site where the circular stapler (4) is actuated to connect previously severed tissue portions. An embodiment of the invention allows tissue portions to be joined without the use of sutures. The buttress material (16) is made up of two regions, one of which serves primarily to secure the buttress material (16) to the stapler (4) prior to acuation, and one of which serves primarily to form the improved seal. The former region is severed and discarded upon activation of the circular stapler (4) to form anastomoses, while the remaining material secures and seals the newly connected tissue. Methods of use and preparation of the buttress material (16) are also described.

A device for delivering fluid to a person includes a reservoir for containing a fluid to be delivered to the person; a fluid transport device for dispensing fluid from the reservoir to the person, the fluid transport device including a proximal end in fluid communication with the reservoir and a distal end having a penetrating member for piercing the skin of the person to facilitate the delivery of fluid to the person through the fluid transport device; a housing containing the reservoir and the fluid transport device, the housing including an exit port for receiving the distal end of the fluid transport device upon injection of the distal end into the person and means for securing a first wall of the housing to the skin of the person; and an injection activation device including a driving mechanism contacting the fluid transport device for driving the penetrating member from a first position within the housing, through the exit port to a second position, external to the housing and into the skin of the person.

Various safe switching mechanisms are provided for use with electrosurgical instruments which prevent arcing between the high-energy contacts as the high-energy source is activated. The switching mechanisms generally include a pair of high-energy contacts and a pair of activation contacts. An actuator is provided which initially engages the high-energy contacts in advance of engagement of the activation contacts to prevent arcing and subsequently disengages the activation contacts in advance of the high-energy contacts as the energy source is deactivated. A method of switching power to an electrosurgical instrument while avoiding damage to high-energy contacts is also disclosed.

A medical manipulator system includes a manipulator, an operating unit for entering operation commands, motors for actuating a working unit, and a controller for energizing the motors based on operation commands supplied from the operating unit. When an activation resetting switch and a resetting switch are operated according to a predetermined procedure, the controller performs a resetting process to return the motors to an origin. The controller is capable of controlling three manipulators. The activation resetting switch is shared by the three manipulators, and there are three resetting switches corresponding to the three manipulators.

An expandable interbody spacer (IBS) device designed to restore the disc height between vertebral bodies. The expandable interbody spacer device has an integral, moveable expansion member or spreader, provided between two plates. The plates are connected by one or more connecting members that retain the plates in a position proximate to one another while allowing the plates to move from a first unexpanded position to a second expanded position upon activation of the expansion member. According to aspects of the invention, the interbody spacer device can be implanted in an unexpanded or collapsed configuration, and then expanded to full height by engaging the expansion member. In other embodiments, the interbody spacer device may take various forms, for example, it may be cashew, rectangular or annular.

There is set forth herein an imaging terminal having an image sensor array and a variable lens assembly for focusing an image onto the image sensor array. In one embodiment, an imaging terminal can include one or more focusing configuration selected from the group comprising a full set focusing configuration, a truncated set focusing configuration and a fixed focusing configuration. When a full set focusing configuration is active, a full set of candidate focus settings can be active when the imaging terminal determines a focus setting of the terminal responsively to a trigger signal activation. When a truncated set focusing configuration is active, a truncated range of candidate focus settings can be active when the imaging terminal determines a focus setting of the terminal responsively to a trigger signal activation. When a fixed focusing configuration is active, the focus setting of the imaging lens assembly can be fixed so that a predetermined lens assembly focus setting is active when a trigger signal is active.

Various embodiments are disclosed for a services policy communication system and method. In some embodiments, a communications device stores a set of device credentials for activating the communications device for a service on a network; and sends an access request to the network, the access request including the set of device credentials.

The present disclosure provides for controlling the collection, manipulation and storage of network performance data and network even data of a network with service assurance capabilities. Upon the receipt of an activation signal, a signal is transmitted to initiate the retrieving of network performance data and network event data generated from at least one network monitor. Such network monitor is adapted for monitoring a network system and the relocating of the data into a common directory. A signal is then transmitted to initiate the manipulation of the data and the loading of the manipulated data into a database.

Systems and methods for interoperable network token processing are provided. A network token system provides a platform that can be leveraged by external entities (e.g., third party wallets, e-commerce merchants, payment enablers / payment service providers, etc.) or internal payment processing network systems that have the need to use the tokens to facilitate payment transactions. A token registry vault can provide interfaces for various token requestors (e.g., mobile device, issuers, merchants, mobile wallet providers, etc.), merchants, acquirers, issuers, and payment processing network systems to request generation, use and management of tokens. The network token system further provides services such as card registration, token generation, token issuance, token authentication and activation, token exchange, and token life-cycle management.

An artificial intervertebral disc and disc nucleus are described herein having chambers and dampening members. The dampening members may be within or outside of the main body of the device. The chambers may be filled with a suitable liquid, gas, or both, and separated by valves to regulate flow of fluid between chambers, within a dampening member, between the main body and dampening member, or all of the above. Chambers may be filled with responsive hydrogels, EPAM, or other suitable materials, and the device may have activation plates or members, a strain gauge, a pressure sensor, or other means for detecting changes in the materials and / or triggering desired changes in the materials in order to mimic the behavior of a healthy native disc or disc nucleus. A control system may be in communication with the device for receiving feedback and delivering stimuli to initiate desired changes in the fluids or other materials. Membranes may be of variable permeability and may be metallized to ensure as low permeability as possible. Dampening members may be filled during manufacture with carbon dioxide or other suitable gas which may be in a supercritical state and allowed to return to ambient temperature and gaseous state or by other means. Methods of manufacture, delivery of the artificial disc and related structures, and methods of treatment are also described.

A Provider Network Controller (PNC) addresses the challenges in building services across Next Generation Network (NGN) architectures and creates an abstraction layer as a bridge, or glue, between the network transport and applications running over it. The PNC is a multi-layer, multi-vendor dynamic control plane that implements service activation and Layer 0-2 management tools for multiple transport technologies including Carrier Ethernet, Provider Backbone Transport (PBT), Multi-protocol Label Switching (MPLS), Transport MPLS (T-MPLS), optical and integrated networking platforms. Decoupling transport controls and services from the network equipment simplifies service creation and provides options for carriers to choose best-in-class equipment that leverages the PNC to enable rapid creation and management of transports and services. The PNC provides Service-Oriented Architecture (SOA) interfaces to abstract transport objects expressly designed to support both wholesale and retail services, and supports service offerings with varied bandwidth and Quality of Service (QoS) requirements, thus achieving enterprise Ethernet economics.