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1043 results about "Quercetin" patented technology

Quercetin is a plant flavonol from the flavonoid group of polyphenols. It is found in many fruits, vegetables, leaves, and grains; red onions and kale are common foods containing appreciable content of quercetin. Quercetin has a bitter flavor and is used as an ingredient in dietary supplements, beverages, and foods.

Quercetin-3-O-acyl ester and preparation method thereof

The invention relates to quercetin-3-O-acyl ester and a preparation method thereof and belongs to the technical field of pharmaceutical chemistry. The preparation method comprises the following steps: taking cheap rutin as a starting raw material and preparing a quercetin-3-O-acyl ester compound through benzylation, hydrolysis under the acidic conditions, esterification, catalytic hydrogenolysis and other reactions. The method has the characteristics of good selectivity, mild reaction condition, high yield, low cost, simplicity and convenience in operation, easiness in industrial production and the like. In addition, the inhibitory effect of the obtained quercetin-3-O-acyl ester on human esophageal squamous carcinoma cells EC9706, human prostatic cancer cells PC-3 and human gastric cancer cells MGC-803 is remarkably superior to that of quercetin; and the quercetin-3-O-acyl ester can be used in the field of foods and medicines and is possible to develop into a new candidate drug for treating tumor.
Owner:ZHENGZHOU UNIV

An electrochemical method for the simultaneous determination of rutin and quercetin based on a graphene-modified electrode

The invention discloses an electrochemical method based on a graphene-modified electrode for simultaneous determination of rutin and quercetin. The graphene-modified electrode is used as a working electrode, and cyclic voltammetry and differential pulse voltammetry are adopted for simultaneous determination of the rutin and the quercetin. Since grapheme is used as a modifying material for the electrode, electrochemical separation of two Chinese flavonoids, the rutin and the quercetin can be achieved on the modified electrode, and the contents of the rutin and the quercetin in sophora flower bud can be determined simultaneously through direct electrochemical determination.
Owner:QINGDAO UNIV

Extraction separation purification and identification of flavonoid monomers in oriental blueberry melanin

This is a method for flavonoid monomer's extraction, separation, purification and structural identification, belonging to flavonoid field. In this invention, the original source blueburry leaves turn to be blueburry leaves melanin solution after ethanol extraction. Then, macroreticular resinous adsorbent is used for crude separation of flavonoid in melanin solution, polyamide and HW-40 for flavonoid monomer's pufification, high efficiency liquid chromatography-mass spectrum and NMRR for structural identification. Finally, we obtain 7 kinds of flavonoid monomer, named A B C D E F and G. Exact structural identification help to determine B C D E and F is quercetin, chrysin, versulin, Kacmpferol and digitoflavone respectively, and their relative contents are 37.51%,2.26%,9.57%,1.72% and 15.16%.
Owner:JIANGNAN UNIV

Method for extracting dihydro quercetin from larch using adsorption method

The adsorption process of extracting dihydro quercetin from larch includes extracting dihydro quercetin from Xingan larch with water as extractant, decolorizing the extracted liquid with active carbon or activated clay, adsorbing the water soluble extracted liquid with polyamide powder as adsorbent, desorbing with desorbing solvent, eliminating solvent from the stripped liquid in vacuum condition to obtain white or yellowish coarse dihydro quercetin powder product. The coarse dihydro quercetin powder product may be recrystallized in water to purify, so as to obtain refined dihydro quercetin product. The process has the obvious technological effects of dihydro quercetin yield near 1.0 % and dihydro quercetin purity up to 98 %.
Owner:GUANGZHOU UNIVERSITY

Pharmaceutical co-crystals of quercetin

A co-crystal composition comprised of Quercetin and at least one antidiabetic agent acts as a combination drug having unique physical properties and biological activity, which differ from both Quercetin in pure form and the at least one antidiabetic agent in pure form. The co-crystal composition may comprise quercetin and metformin. The co-crystals of quercetin and metformin may be prepared by grinding the compounds, and used in pharmaceutical compositions comprising these co-crystals. Co-crystal compositions of quercetin and Metformin may be used in combination with other anti-diabetic agents, including DPP-IV inhibitors.
Owner:NUTRACRYST THERAPEUTICS PRIVATE

Dermatological pharmaceutical composition for the treatment of skin inflammation diseases, such as dermatitis, atopic dermatitis, vitiligo, alopecia areata, acne, psoriasis, pruritus or combinations of same

The invention relates to a dermatological pharmaceutical composition for the treatment of skin inflammation diseases, such as dermatitis, atopic dermatitis, vitiligo, alopecia areata, acne, psoriasis and pruritus. The invention comprises a base anti-inflammatory agent, such as indometacin; one or more optional active ingredients selected alternatively from among at least a corticoid and an antibiotic; and a combination of topical antioxidants used to potentiate the anti-inflammatory effect, selected from among green tea, lipoic acid, curcumin, ascorbyl palmitate, Coenzyme Q10, resveratrol, Pycnogenol™, L-camosine, taurine, vitamin E, vitamin C, papaya extract, isoflavones, manganese, lycopene and quercetin. At least one of the topical antioxidants is a peroxisome proliferator-activated receptor-gamma (PPAR-γ) activator. The invention also includes at least one antioxidant substance with an antiproliferative effect on keratonocytes, e.g. manganese, and at least one substance that blocks tumour necrosis factor-alpha (TNF-α) or other cytokines that provoke the acute phase of the inflammatory reaction, also with an antiproliferative effect, e.g. pentoxifylline.
Owner:UMBERT MILL IGNACIO

Soft capsule oral care agent and preparation method thereof

The invention relates to a soft capsule oral care agent and a preparation method thereof. The soft capsule oral care agent comprises one or several of the following natural product extracts with anti-inflammation and bactericidal activity: thymol, menthol crystal, tea polyphenol, clove oil, wintergreen oil, eucalyptus oil, blumea oil, cinnamon oil, tea tree essential oil, lavender oil, lemon oil, litsea cubeba oil, citronella oil, patchouli oil, perilla oil, zanthoxylum oil, geranium essential oil, juniper berry essential oil, evening primrose essential oil, grape seed oil, origanum oil, rose essential oil, aloe powder, rutin, hydroxyrutin, dihydroquercetin, curcumin, bisdethoxy curcumin, aloesin, barbaloin, ferulic acid, citric acid, tea purine, bitter betaine and the like, wherein the natural product extracts account for 5-75 weight percent of the soft capsule oral care agent. Moreover, the invention discloses a preparation method for the soft capsule oral care agent. The soft capsule oral care agent has the characteristics of broad antibacterial spectrum, efficient and quick effect, high safety and no toxin. The advantages of oral care products, such as chewing gum, mouth wash and the like, are integrated, and the defects of a traditional oral care agent are discarded by the soft capsule oral care agent. The soft capsule oral care agent is good in effect, convenient in carrying and simple in application.
Owner:广州安德生物科技有限公司

High-internal-phase emulsion of soybean protein isolate-pectin compound stabilized quercetin and preparation method of high-internal-phase emulsion

The invention belongs to the technical field of emulsions, and discloses a high-internal-phase emulsion of soybean protein isolate-pectin compound stabilized quercetin and a preparation method of thehigh-internal-phase emulsion. The method comprises the following steps: dissolving soybean protein isolate in distilled water to obtain a soybean protein isolate solution; dissolving pectin in distilled water, and adjusting the pH value to obtain a pectin solution; mixing the soybean protein isolate solution with the pectin solution; adjusting the pH value of the solution to 3.0-11.0; mixing the obtained solution with vegetable oil containing quercetin in proportion, then carrying out ultrasonic treatment, and carrying out centrifuging to obtain the high-internal-phase emulsion of soybean protein isolate-pectin compound stabilized quercetin. According to the invention, no surfactant is needed, and the obtained oil-in-water type emulsion is small in particle size, good in viscoelasticity and high in stability and has an excellent protection or controlled release effect on quercetin. The preparation method is low in instrument requirement, the method is simple and is easy to operate, andgood prospects are achieved in application aspects of novel nutrient substance conveying carriers and food structure modification base materials.
Owner:NANJING FORESTRY UNIV
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