The invention relates to a preparation method for a biomimetic
mussel adhesive used for adhesion on a wet surface and
underwater curing. The method is characterized in that the biomimetic
mussel adhesive is composed of two components including A and B, wherein the component A is a
methanol solution of a
polymer containing
catechol groups; the
polymer containing
catechol groups is obtained in the manner that N-vinyl pyrrolidone and a polymerizable
catechol derivative
monomer are subjected to free
radical polymerization and further subjected to deprotection; the component B is a crosslinking curing agent. The method has the advantages as follows: 1, the synthetic method is simple and efficient,
raw material and reagents used in the reaction process are low in price and easy to get, and amplification in the operation process and industrial production are facilitated; 2, the biomimetic
mussel adhesive has certain
biocompatibility and initial adhesion performance, can be used for adhesion on the wet surface and
underwater curing, and has the
bonding strength being over 1 MPa, so as to be applied to adhesion of human tissue and adhesion in the wet environment of commonly-used base material as well as adhesion under the water. According to the invention, perfect combination between synthetic
macromolecule and natural mussel attachment proteins is successfully realized, the technical
bottleneck about the current biomimetic mussel adhesive is expected to break through, and meanwhile, a new approach for
shellfish-based development of biomimetic
high polymer material is provided.