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651 results about "Vitiligo" patented technology

A condition in which the melanocytes, the pigment cells of the skin, are destroyed causing affected areas to turn pale. Often seen as patches of white skin.

Compositions for reducing oxidative stress and uses thereof

The present invention relates to the use of one or more tripeptides selected from the group consisting of NLys-Pro-ValC, NLys-Pro-ThrC and NpGLu-His-ProC for the reduction of oxidative stress. The above tripeptides are particularly useful for the treatment of a disease or damage caused by oxidative stress; such as vitiligo, scleroderma, necrosis, or erythema; furthermore, a disease or damage of the hair, like premature hair loss or premature formation of grey hair. Furthermore the invention relates the cosmetic use of the above tripeptides, in particular against skin aging. Further the invention relates cosmetic compositions containing at least one of said tripeptides.
Owner:UNIVSKLINIKUM MUNSTER

HSP70-Based Treatment for Autoimmune Diseases and Cancer

A non-natural HSP70 activating region that activates dendritic cells. Polypeptides that bind to the HSP70 activating region can be used to treat autoimmune diseases, such as vitiligo, by binding to HSP70 and preventing HSP70 form activating dendritic cells. The HSP70 binders can be constructed in the form of fusions proteins with a trimerizing structural element that may associate to form a trimeric complex. Pharmaceutical compositions and methods for treating vitiligo using the HSP70 binding proteins, fusion proteins and complexes.
Owner:ANAPHORE INC

Methods and mechanisms involving hyperpigmentation particularly for african american skin

Sets of genes are identified that show modulated activity in hyperpigmented sun-exposed (HE) and non-hyperpigmented sun-exposed (NHE) skin, when compared to non-hyperpigmented non-exposed (NHNE) skin. The modulated sets of genes reveal important information about the genetic changes that take place in skin as a result of environmental exposure and damage. The modulated sets of genes may be used to fabricate custom DNA microarrays for evaluating patients with skin diseases or disorders. The microarrays may also be used to screen new substances for treating skin diseases and disorders. The modulated gene sets, and substances that target them, may also be used to develop therapies for individuals who suffer from hypopigmentation, such as those with Fitzpatrick type I skin or vitiligo.
Owner:HAMPTON UNIVERSITY

Dermatological pharmaceutical composition for the treatment of skin inflammation diseases, such as dermatitis, atopic dermatitis, vitiligo, alopecia areata, acne, psoriasis, pruritus or combinations of same

The invention relates to a dermatological pharmaceutical composition for the treatment of skin inflammation diseases, such as dermatitis, atopic dermatitis, vitiligo, alopecia areata, acne, psoriasis and pruritus. The invention comprises a base anti-inflammatory agent, such as indometacin; one or more optional active ingredients selected alternatively from among at least a corticoid and an antibiotic; and a combination of topical antioxidants used to potentiate the anti-inflammatory effect, selected from among green tea, lipoic acid, curcumin, ascorbyl palmitate, Coenzyme Q10, resveratrol, Pycnogenol™, L-camosine, taurine, vitamin E, vitamin C, papaya extract, isoflavones, manganese, lycopene and quercetin. At least one of the topical antioxidants is a peroxisome proliferator-activated receptor-gamma (PPAR-γ) activator. The invention also includes at least one antioxidant substance with an antiproliferative effect on keratonocytes, e.g. manganese, and at least one substance that blocks tumour necrosis factor-alpha (TNF-α) or other cytokines that provoke the acute phase of the inflammatory reaction, also with an antiproliferative effect, e.g. pentoxifylline.
Owner:UMBERT MILL IGNACIO

Tissue engineering material-based culture method and applications of melanophore

The invention discloses a tissue engineering material-based culture method and applications of melanophore. In the method of the invention, the tissue engineering technology is used to build carrier material with good biocompatibility and perform culture (co-culture) and transfer of melanophore or melanophore, fibroblast and keratinocyte and the method can be used in depigmentation diseases such as vitiligo and for the regulation of skin color. The invention relates to the preparation of the carrier material with biocompatibility and the building and transplanting of the cell-carrier composite material. The carrier material can be used to provide good carrier for cell culture, maintain cellular activity and solve the problem that the cell suspension is easy to lose in the cellular transplantation process; the inoculum density and culture time of cells can be regulated at the same time, the regulation to the skin colors of different individuals can be realized; and the carrier materialhas good performances such as damage resistance, tear resistance and easy transfer, has good function of promoting wound healing, and satisfies the use requirements of the large-area depigmentation disease and the regulation of skin color.
Owner:HANGZHOU THIRD HOSPITAL +1

Application of 20(R)-ginsenoside Rg3 in preparation of medicines for treating leucoderma

The invention discloses a novel application of 20(R)-ginsenoside Rg3 in preparation of medicines for relieving or / and treating leucoderma. Tests show that the 20(R)-ginsenoside Rg3 is significant in treating effects for the leucoderma, quick in effectiveness, low in toxic and side effects, safe, efficient, stable, simple in preparation process, suitable for industrial production, and prone to popularization. The application provides a novel medicine source for preventing and treating the leucoderma and complications thereof.
Owner:富力

Drug for treating leucoderma and preparation method thereof

The invention discloses a drug for treating leucoderma and a preparation method thereof. The drug is prepared from gecko, human placenta, fructus psoraleae, prepared rehmannia root, pulp of cornus officinalis, dendrobium, radix astragali, pilose antler, fleece-flower root, glossy privet fruit, donkey-hide gelatin, tortoise-plastron glue, semen cuscutae, rhizoma polygonati, root of Angelicasinensis (Oliv)Diels, semen astragali complanati, raspberry, wolfberry, red ginseng, pseudo-ginseng, ganoderma atrum, radix salviae miltiorrhizae, stigma croci, long-nosed pit viper, tribulus terrestris, ligusticum wallichii, dahurian angelica root, divaricate saposhnikovia root, balloonflower root, tree peony bark, tuber fleeceflower stem, trogopterus dung, white-stiff silkworm, fruit of Chinese magnoliavine, katsumadai seed, medicated leaven, chicken's gizzard membrane, radish seed, bighead atractylodes rhizome, poria cocos, fructus amomi, herba siegesbeckiae, coix seed, black bean hull, esliptae herba, duckweed, motherwort, lithospermum, common clubmoss herb, periostracum serpentis, periostracum cicada, tamarix chinensis, native copper, Chinese-date, dried orange peel and madder. The drug does not damage the human body, realizes treatment on both symptoms and root causes and thoroughly cures leucoderma.
Owner:徐辉

Photoelectric device for vitiligo treatment

The invention discloses a photoelectric device for vitiligo treatment. Low-price deep ultraviolet LED light sources are adopted; beam combination and light intensity graded adjustment of ultraviolet light are realized through photoelectric devices; a computer vision technology is utilized to realize intelligent detection on a plurality of main parameters of affected skin; feedback control on the deep ultraviolet LED light sources, galvanometers and a liquid lens can be completed; and therefore, the cost of the vitiligo treatment equipment is greatly decreased, and the intelligent degree of the vitiligo treatment equipment is improved, and the work intensity of doctors can be reduced.
Owner:FOSHAN UNIVERSITY

Medicine for external use for treating psoriasis, leucoderma, fungus infection and bromhidrosis

The invention relates to a medicine for external use for treating skin diseases, and in particular relates to a medicine for external use for treating psoriasis, leucoderma, fungus infection and bromhidrosis, aiming at making up the defects of the existing medicine for external use for treating psoriasis, leucoderma, fungus infection and bromhidrosis; the medicine for external use comprises silver element and a pharmaceutically acceptable carrier, wherein the content of the silver element is 0.000001-0.005g/ml; and the silver element is one in nano-silver, silver salt, salt solution of silver or complexing silver, or mixture formed by mixing several in nano-silver, silver salt, salt solution of silver and complexing silver according to any proportion. By a plurality of years of clinical experience, the study for the drug properties and the observation for the treatment effect of the medicine of the inventor, the components and the ratio of the medicine are adjusted for a plurality of times, and the formulation of the medicine for external use is finally confirmed; the medicine for external use effectively reduces the medication time of a patient, thus reducing the treatment cost; and the medicine for external use is ideal is treatment effect, higher in cure rate and lower in recurrence rate, thus having important clinical significance as well as higher social value and marketable value.
Owner:李泽红
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