119 results about "Mycosis" patented technology

Topically applicable dermatological / cosmetic compositions suited for ungual / peri-ungual administration for the treatment of a variety of pathologies, including fungal pathologies, such as onychomycosis, contain (a) at least one biologically active agent (e.g., antifungal) and (b) at least two of the pro-penetrating agents selected from the group consisting of urea, an organic acid and an ethoxydiglycol, the at least two-pro-penetrating agents respectively being present in effective amounts as to synergistically improve the ungual / peri-ungual bioavailability of the at least one biologically active agent.

The invention includes devices and methods for obtaining samples of blood or other bodily fluids with reduced levels of contamination. Fluid obtained from a subject may be contaminated by skin cells, bacteria, fungi, viruses, phages, their respective RNA, DNA, and / or other undesirable molecules, or disinfectants. A first amount of fluid is injected from the subject through an distal needle and a proximal needle penetrates a first portion of a device having a sequestration chamber with sub-atmospheric pressure therein. A first portion of the fluid, containing contaminants, is deposited into the sequestration chamber. The proximal needle is then moved through a second portion of the sequestration chamber and into a collection container. Because contaminants are removed from the sample, analysis and diagnosis of a subject's condition becomes more reliable and accurate. Additional devices and methods can be used to obtain relatively uncontaminated samples from cell culturing vessels.

The nanometer antifungal econazole nitrate emulsion medicine consists of econazole nitrate, surfactant, oil and distilled water. Its preparation process includes the following steps: weighing the materials; mixing the surfactant and oil and dissolving econazole nitrate in dimethyl sulphoxide; mixing the solution of econazole nitrate with the surfactant and oil; and final adding distilled water slowly while stirring to form stable homogeneous transparent nanometer antifungal econazole nitrate emulsion medicine. The medicine is used in treating candidal tinea corporis, tinea cruris and tinea pedis, aural mycosis, seborrheic dermatitis, etc. The medicine is absorbed through skin to enter into blood circulation, and this avoids the first pass effect of liver, prolongs the medicine release and prevents stimulation to gastrointestinal tract. The preparation process is simple and low in power consumption.

The nanometer antifungal econazole nitrate emulsion medicine consists of econazole nitrate, surfactant, oil and distilled water. Its preparation process includes the following steps: weighing the materials; mixing the surfactant and oil and dissolving econazole nitrate in dimethyl sulphoxide; mixing the solution of econazole nitrate with the surfactant and oil; and final adding distilled water slowly while stirring to form stable homogeneous transparent nanometer antifungal econazole nitrate emulsion medicine. The medicine is used in treating candidal tinea corporis, tinea cruris and tinea pedis, aural mycosis, seborrheic dermatitis, etc. The medicine is absorbed through skin to enter into blood circulation, and this avoids the first pass effect of liver, prolongs the medicine release and prevents stimulation to gastrointestinal tract. The preparation process is simple and low in power consumption.

The invention provided Mucorales CotH polypeptides and encoding nucleic acid molecules. The Mucorales CotH polypeptides and encoding nucleic acids can be advantageously used to diagnose, treat or prevent fungal conditions, in particular mucormycosis.

Topically applicable dermatological / cosmetic compositions suited for ungual / peri-ungual administration for the treatment of a variety of pathologies, including fungal pathologies, such as onychomycosis, contain (a) at least one biologically active agent (e.g., antifungal) and (b) at least two of the pro-penetrating agents selected from the group consisting of urea, an organic acid and an ethoxydiglycol, the at least two-pro-penetrating agents respectively being present in effective amounts as to synergistically improve the ungual / peri-ungual bioavailability of the at least one biologically active agent.

The invention discloses an oil-in-water compound ketoconazole nano-medicament. The grain diameter of the medicament is 1-100nm. The oil-in-water compound ketoconazole nano medicament comprises the following raw materials in percentage by weight: 0.01-8.0 percent of ketoconazole, 0.01-10 percent of eugenol, 0.001-5.0 percent of clobetasol propionate, 25.0-45.0 percent of surfactant, 0-10.0 percentof cosurfactant, 0.1-25.0 percent of oil and the balance of distilled water. The oil-in-water compound ketoconazole nano-medicament can be used for treating stubborn skin mycotic infection, mycodermatitis, chronic mucocutaneous candidiasis, dermatitis blastomycosis, coccidioidomycosis, histoplasmosis, chromoblastomycosis and paracoccidioidomycosis, and dermatomycosis and tinea versicolor caused by dermatophyte and microzyme as well as trichophyton disease, scytitis and pruritus. The oil-in-water compound ketoconazole nano-medicament has the advantages of strong osmosis, favorable stability, favorable infiltrating property, durable acting time, remarkable effect, low cost, simple preparation method and convenience in popularization and application.

The invention discloses a heterometrus spinifer breeding method and belongs to the field of arthropod breeding study. The problems of low farrowing rate of female scorpion, low survival rate of young scorpion, difficulty in decrustation of young scorpion, death of adult scorpion and the like are solved. A heterometrus spinifer bred by the method is high in disease resistance, high in farrowing rate and high in growing speed, the survival rate is up to 95 percent, and the economic benefit is increased by 30 percent. The method comprises the following steps of selecting and breeding male scorpions, breeding and managing pregnant scorpions, breeding and managing young scorpions, performing daily management, preventing and controlling diseases, and preventing and controlling main natural enemy, wherein the indoor temperature is kept to be 32+ / -2 DEG C, the air humidity is kept to be between 70 and 80 percent, robust adult female scorpions and male scorpions are selected to be separately bred for 20 to 30 days, two female scorpions and a male scorpion are placed in a breeding room to copulate and propagate, the pregnant scorpion gives birth to young scorpions 4 to 6 months later, about 50 days after the young scorpions are born, the young scorpions are separated from the female scorpions, the density is that 200 to 250 young scorpions are contained in one box, the young scorpions which are 3 years old are grouped, and after being bred for 14 to 16 months, the young scorpions are grown into adult scorpions. Mycosis and bacterial wilt are prevented and controlled by enhancing daily management, and natural enemies, such as ants and geckos are prevented and controlled by taking effective measures.

The Chinese medicine preparation for preventing and treating disease of bee is prepared with basket kern, skullcap root, pine needle, licrorice, purslane, taraxacum, haw and rhubarb. It is used to treat bee's pericystis mycosis, lava disease, crawl disease, etc. caused by fungi, bacteria, virus and sporozoan infection, strengthening bee's immunity and prolong bee's life. It has also disinfection effect, no toxic side effect and pollution on bee and no harm to human body.

A Chinese medicine in the form of powder or lotion for treating skin mycosis is prepared from 15 Chinese-medicinal materials including green tea, dandelion herb, phellodendron bark, mint, etc.

This invention relates to a compound, as defined in the specification and as represented by the compound of formula (I):useful in the treatment of mycoses, to compositions containing it and its use in therapy.