Chinese medicine for treating dermatomycosis and its preparing process

A technology for dermatophytosis and traditional Chinese medicine preparations, applied in skin diseases, antifungal agents, and pharmaceutical formulations, etc.

Inactive Publication Date: 2006-01-18
SHANDONG MINGREN FURUIDA PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] (1) The curative effect is the same as that of the positive control drug Dakning Cream, and the total effective rate of the two groups has no significant difference after statistical processing. There are many antifungal drugs on the market, but pure Chinese medicine is used to treat superficial mycosis based on TCM syndrome differentiation. And there are still few traditional Chinese medicine preparations with the same curative effect as western medicine

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0014] Take 50g of Cortex Phellodendri, add 90% ethanol, reflux and extract twice, each time for 1.5 hours, combine the extracts, filter, and recover the ethanol from the filtrate under reduced pressure, and continue to concentrate until the relative density is 1.07~1.08 (80°C) concentrated solution, add water 200ml, mix well, heat to boiling, place at room temperature for 24 hours, filter, and use the filtrate for later use. Take 45g of Sophora flavescens, add water and decoct twice, the first time for 2 hours, the second time for 1.5 hours, combine the decoction, filter, and concentrate the filtrate into a concentrated solution with a relative density of 1.09-1.10 (80°C), add ethanol to make The alcohol content reaches 80%, mix well, stand for 24 hours, filter the supernatant, recover ethanol from the filtrate under reduced pressure, combine with the above filtrate, concentrate into a thick paste with a relative density of 1.25-1.26 (80°C), reduce it at 60°C Press and dry in...

Embodiment 2

[0016] Take 70g of Cortex Phellodendri, add 40% ethanol, reflux and extract twice, each time for 1.5 hours, combine the extracts, filter, and recover the ethanol from the filtrate under reduced pressure, and continue to concentrate until the relative density is 1.07~1.08 (80°C) concentrated solution, add water 60ml, mix well, heat to boiling, place at room temperature for 24 hours, filter, and use the filtrate for later use. Take 40g of Sophora flavescens, add water and decoct twice, the first time for 2 hours, the second time for 1.5 hours, combine the decoction, filter, and concentrate the filtrate into a concentrated solution with a relative density of 1.09-1.10 (80°C), add ethanol to make The alcohol content reaches 70%, mix well, stand for 24 hours, filter the supernatant, recover ethanol from the filtrate under reduced pressure, combine with the above filtrate, concentrate into a thick paste with a relative density of 1.25-1.26 (80°C), reduce it at 60°C Press and dry int...

Embodiment 3

[0018] Take 60g of Cortex Phellodendri, add 80% ethanol, reflux and extract twice, each time for 1.5 hours, combine the extracts, filter, and recover the ethanol from the filtrate under reduced pressure, and continue to concentrate until the relative density is 1.07~1.08 (80°C) concentrated solution, add water 300ml, mix well, heat to boiling, stand at room temperature for 24 hours, filter, and use the filtrate for later use. Take 35g of Sophora flavescens, add water and decoct twice, the first time for 2 hours, the second time for 1.5 hours, combine the decoction, filter, and concentrate the filtrate into a concentrated solution with a relative density of 1.09-1.10 (80°C), add ethanol to make The alcohol content reaches 50%, mix well, stand for 24 hours, filter the supernatant, recover the ethanol from the filtrate under reduced pressure, combine with the above filtrate, concentrate into a thick paste with a relative density of 1.25-1.26 (80°C), reduce it at 60°C Press and dr...

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PUM

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Abstract

The invention relates to a traditional Chinese medicinal composition for treating dermatophytosis, which is prepared from crab's shell, corktree bark, flavescent sophora root, sea tangle and clam shell. The dosage form of the preparation includes ointment, cream, gelling agent, liniment and lotion.

Description

technical field [0001] The invention relates to a traditional Chinese medicine preparation, especially a traditional Chinese medicine preparation for treating superficial fungal infections (hand, foot, body, jock itch) and a preparation method thereof. Its dosage forms include ointment, cream, gel, liniment, lotion, Pharmaceutical preparations and any external dosage forms in pharmacy belong to the field of traditional Chinese medicine preparations. Background technique [0002] Superficial fungal infection is one of the common clinical skin diseases. It belongs to the syndrome of damp-heat invasion in traditional Chinese medicine. Secondary infections such as lymphangitis seriously hinder people's normal work and life, and the recurrence rate of this disease is high and difficult to heal for many years. Currently, chemical drugs and antibiotics are used to treat superficial fungal infections of the skin, while traditional Chinese medicine uses syndrome differentiation. As ...

Claims

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Application Information

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IPC IPC(8): A61K36/756A61K36/48A61K36/02A61P17/00A61P31/10A61K35/612A61K35/618
Inventor 凌沛学张玲曲延伟
Owner SHANDONG MINGREN FURUIDA PHARMA
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