179 results about "Otic Agents" patented technology

Topically applicable dermatological / cosmetic compositions suited for ungual / peri-ungual administration for the treatment of a variety of pathologies, including fungal pathologies, such as onychomycosis, contain (a) at least one biologically active agent (e.g., antifungal) and (b) at least two of the pro-penetrating agents selected from the group consisting of urea, an organic acid and an ethoxydiglycol, the at least two-pro-penetrating agents respectively being present in effective amounts as to synergistically improve the ungual / peri-ungual bioavailability of the at least one biologically active agent.

Stable, topically applicable, non-greasy and non-tacky oil-in-water (O / W) anti-inflammatory emulsions, useful, e.g., for the treatment of psoriasis, contain: a. a therapeutically effective amount of at least one steroidal anti-inflammatory agent, notably clobetasol propionate; b. a pro-penetrating system which includes at least one pro-penetrating glycol and at least one other pro-penetrating agent; and c. at least one polymeric emulsifier not sensitive to electrolytes, for example not an acrylate / C10-C30 alkyl acrylate copolymer, formulated into a topically applicable, pharmaceutically acceptable vehicle therefor.

The cerebrospinal fluid and intracranial pressure are two major reasons why central nervous system is so vulnerable to injuries. A composition and method for treating injured central nervous tissue, or preventing injury to central nervous system tissue is provided. The composition is comprised of a combination of colloidal osmotic agents and crystal osmotic agents. The method comprise of: a). Withdrawing cerebrospinal fluid from the subarachnoid spaces around the tissue to be treated or protected and b). Injecting the composition which is dissolved by patient's own cerebrospinal fluid into subarachnoid spaces. The treatment can be augmented with agents that suppress production of cerebrospinal fluid, or with other known neuroprotective agents.

The present invention provides a pesticide formulation that is effective, non-persistent in the environment, and meets the criteria for use in organic food production as set for the by the United States Department of Agriculture (USDA) and Organic Materials Review Institute (OMRI). The formulation may be used for the control and eradication of pathogens such as germs and viruses, insects, insect larvae, mold, slime and fungus, and algae. The compositions provide a formulation containing an oxidizing compound in conjunction with a botanically derived surfactant / membrane permeablization agent. The formulation typically contains a hydrogen peroxide generating compound(s) and saponin glycoside compounds, which, in combination, show enhanced activity towards insects, pathogens algae, slime, mold and fungus. The method is exemplified by applying an effective amount of a composition containing an aqueous mixture of hydrogen peroxide and surface-active saponin botanical extracts preferentially derived from Quillaja saponaria and / or Yucca schidigera, to water bodies, surfaces, and in or on turf. The composition is also effective for control of odors and sulfurous black layer found in turf.

The invention relates to a bactericidal composition with active ingredients to be pyrazole-kresoxim-methyl and thiram, and belongs to the bactericidal composition pesticide technology field. The bactericidal composition contains the active ingredients to be the pyrazole-kresoxim-methyl and the thiram, the weight ratio of which are 1:40-40:1 and the weight percentages are 1%-90%; and the bactericidal composition can be prepared into wettable powder, water dispersible granules, a suspending agent, aqueous emulsion, micro-emulsion, or other formulations. The bactericidal composition at least contains a carrier and an accessory ingredient, wherein at least one is a surface active agent which can be an emulsifier, a dispersant, a humectant or a penetrant. The carrier can be water, organic solvent or latent solvent, and filling material according to the different preparation formulations. A stabilizing agent, a thickening agent, a defoaming agent, a cementing agent and other functional accessory ingredients can be added when necessary. The bactericidal composition can be used for preventing and curing a plurality of plant diseases caused by oomycetes, ascomycetes, basidiomycetes, deuteromycetes, and so on, so as to play an important role in enhancing effects, curing diseases, reducing cost, delaying pesticide resistance, etc.

Topically applicable dermatological / cosmetic compositions suited for ungual / peri-ungual administration for the treatment of a variety of pathologies, including fungal pathologies, such as onychomycosis, contain (a) at least one biologically active agent (e.g., antifungal) and (b) at least two of the pro-penetrating agents selected from the group consisting of urea, an organic acid and an ethoxydiglycol, the at least two-pro-penetrating agents respectively being present in effective amounts as to synergistically improve the ungual / peri-ungual bioavailability of the at least one biologically active agent.