The invention relates to systems and methods for assessing
blood flow in single or multiple vessels and segments, for assessing
vascular health, for conducting clinical trials, for screening therapeutic interventions for effect, for assessing risk factors, for evaluating
intracranial pressure and for analyzing the results in a defined manner. The invention enables
direct monitoring of therapies, substances and devices on blood vessels, especially those of the cerebral vasculature. Relevant
blood flow parameters include mean flow velocity, systolic acceleration, and pulsatility index. Measurement and analysis of these parameters, and others, provides details regarding the
vascular health of individual and multiple vessels and a global analysis of an individual's overall
vascular health. The invention is applicable as both a
system and method for monitoring and improving the design, performance, marketing and use of
vascular stents. In particular, the invention enables DVA-assisted stenting procedures, including both pre-operative and post-operative management.