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4777 results about "Risk stroke" patented technology

The main risk factor for stroke is high blood pressure. Other risk factors include tobacco smoking, obesity, high blood cholesterol, diabetes mellitus, a previous TIA, and atrial fibrillation. An ischemic stroke is typically caused by blockage of a blood vessel, though there are also less common causes.

Surgical stapling instrument with multistroke firing incorporating an anti-backup mechanism

A surgical stapling and severing instrument particularly suited to endoscopic procedures incorporates a handle that produces separate closing and firing motions to actuate an end effector. In particular, the handle produces multiple firing strokes in order to reduce the required amount of force required to fire (i.e., staple and sever) the end effector. A linked transmission reduces the required handle longitudinal length, yet achieves a rigid, strong configuration when straightened for firing. A traction biased firing mechanism avoids binding in driving this straightened linked rack in cooperation with an anti-backup mechanism, with a lockout mechanism that prevents releasing the closure trigger during firing. Furthermore, an external indicator gives feedback to the surgeon as to how far firing has progressed, as well as providing a manual retraction capability.
Owner:CILAG GMBH INT

Surgical stapling instrument incorporating a multi-stroke firing mechanism with return spring rotary manual retraction system

A surgical stapling and severing instrument particularly suited to endoscopic procedures incorporates a handle that produces separate closing and firing motions to actuate an end effector. In particular, the handle produces multiple firing strokes in order to reduce the required amount of force required to fire (i.e., staple and sever) the end effector. A linked transmission reduces the required handle longitudinal length, yet achieves a rigid, strong configuration when straightened for firing. A traction biased firing mechanism avoids binding in driving this straightened linked rack in cooperation with an anti-backup mechanism, with a lockout mechanism that prevents releasing the closure trigger during firing. Furthermore, an external indicator gives feedback to the surgeon as to how far firing has progressed, as well as providing a manual retraction capability.
Owner:ETHICON ENDO SURGERY INC

Surgical stapling and cutting instrument with manually retractable firing member

A surgical stapling and severing instrument particularly suited to endoscopic procedures incorporates a handle that produces separate closing and firing motions to actuate an end effector. In particular, the handle produces multiple firing strokes in order to reduce the required amount of force required to fire (i.e., staple and sever) the end effector. A linked transmission reduces the required handle longitudinal length, yet achieves a rigid, strong configuration when straightened for firing. A traction biased firing mechanism avoids binding in driving this straightened linked rack. The instrument further has a manually actuatable retraction system that does not require the use of additional springs or other mechanisms to generate retraction forces which must be overcome when generating the forces necessary to fire the device. In various embodiments, the retraction system provides a visual indication to the surgeon as to how far firing has progressed.
Owner:CILAG GMBH INT

Surgical stapling instrument incorporating a multistroke firing mechanism having a rotary transmission

A surgical stapling and severing instrument particularly suited to endoscopic procedures incorporates a handle that produces separate closing and firing motions to actuate an end effector. In particular, the handle produces multiple firing strokes in order to reduce the required amount of force required to fire (i.e., staple and sever) the end effector.
Owner:CILAG GMBH INT

Rotary actuatable closure arrangement for surgical end effector

A surgical instrument may include an end effector, an input drive shaft, a closure drive, and / or a firing drive. The end effector may comprise a jaw assembly including a first jaw member and a second jaw member. The end effector may comprise an I-beam member axially translated between a proximal position and a distal position within the end effector. In one embodiment, the input drive shaft may selectively engage the firing drive and / or the closure drive. In one configuration, the closure drive is threadedly engaged with the firing drive allowing the input drive shaft, during a firing stroke, to simultaneously move the closure drive and the firing drive until the closure drive is disengaged from the firing drive. On a reverse stroke, the closure drive may be reengaged with the firing drive.
Owner:CILAG GMBH INT

Anastomosis instrument and method for performing same

A surgical instrument for anastomosis of first and second blood vessels includes a housing having distal and proximal ends and an actuator disposed therebetween. The actuator includes a handle and a link assembly, the link assembly being movable through a firing stroke in response to movement of the handle. The instrument also includes a disposable loading unit releasably attached to the distal end of the housing in mechanical cooperation with the actuator. The disposable loading unit supports a plurality of surgical fasteners, which deform upon movement of the actuator and the link assembly through the firing stroke.
Owner:TYCO HEALTHCARE GRP LP

Anastomosis instrument and method

A surgical instrument for performing an anastomosis includes a housing having proximal and distal ends and a shaft extending from the distal end of the housing. The instrument also includes an actuator attached to the housing and a disposable loading unit configured for selective attachment to the shaft. The disposable loading unit includes a fastener support member configured and dimensioned to support an array of surgical fasteners thereon and a fastener pusher member which is movable through a firing stroke in response to movement of the actuator to deform the surgical fasteners.
Owner:UNITED STATES SURGICAL CORP

Multiple clip applier apparatus and method

A surgical clip applier includes a train of clips disposed in a plane with a single clip removed from the train of clips and disposed in a staging position. A pair of jaws are adapted to receive the single clip from the staging position by operation of a jaw loader moveable outside the plane of the train of clips. In an associate method, a handle assembly is provided which is moveable in an open stroke and a closed stroke. A source of surgical clips are provided along with a pair of jaws which are adapted to receive one of the clips as the handle assembly is moved in an open stroke, the jaws are open to receive the clip. Following the opening of the jaws, a jaw loader is extended to a position between the jaws to move the clip into the jaws. The handle assembly is moveable in a closed stroke during which the jaws are closed to crimp the clip. Prior to this closing of the jaws, the jaw loader is retracted from the position between the jaws leaving the clip in the jaws.
Owner:APPL MEDICAL RESOURCES CORP

Neural regeneration peptides and methods for their use in treatment of brain damage

The invention discloses a family of peptides termed NRP compounds or NRPs that can promote neuronal migration, neurite outgrowth, neuronal proliferation, neural differentiation and / or neuronal survival, and provides compositions and methods for the use of NRPs in the treatment of brain injury and neurodegenerative disease. NRP compounds can induce neurons and neuroblasts to proliferate and migrate into areas of damage caused by acute brain injury or chronic neurodegenerative disease, such as exposure to toxins, stroke, trauma, nervous system infections, demyelinating diseases, dementias, and metabolic disorders. NRP compounds may be administered directly to a subject or to a subject's cells by a variety of means including orally, intraperitoneally, intravascularly, and directly into the nervous system of a patient. NRP compounds can be formulated into pharmaceutically acceptable dose forms for therapeutic use. Methods for detecting neural regeneration, neural proliferation, neural differentiation, neurite outgrowth and neural survival can be used to develop other neurally active agents.
Owner:CURONZ HLDG

Sensors for detecting substances indicative of stroke, ischemia, or myocardial infarction

ActiveUS20060079740A1Thickness minimizationTransport of glucose to the sensor is not altered over timeStentsCatheterMetaboliteCitrulline
A sensor is disclosed, for implantation within a blood vessel to monitor a substance in or property of blood. In one embodiment, the sensor detects nitric oxide or a nitric oxide metabolite. In another embodiment, other substances such as glutamate, aspartate, arginine, citrulline, acetylcholine, calcium, potassium, or dopamine are monitored. The sensor may be attached to a support structure such as a stent, guidewire, or catheter. In a further embodiment, a catheter is disclosed that extracts patient fluid to a sensor outside the body for monitoring a substance or property of the patient fluid. Methods are also disclosed.
Owner:SILVER JAMES H +1

Surgical stapling instrument incorporating a multistroke firing position indicator and retraction mechanism

A surgical stapling and severing instrument particularly suited to endoscopic procedures incorporates a handle that produces separate closing and firing motions to actuate an end effector. In particular, the handle produces multiple firing strokes in order to reduce the required amount of force required to fire (i.e., staple and sever) the end effector. A linked transmission reduces the required handle longitudinal length, yet achieves a rigid, strong configuration when straightened for firing. A traction biased firing mechanism avoids binding in driving this straightened linked rack in cooperation with an anti-backup mechanism, with a lockout mechanism that prevents releasing the closure trigger during firing. Furthermore, an external indicator gives feedback to the surgeon as to how far firing has progressed, as well as providing a manual retraction capability.
Owner:CILAG GMBH INT

Indwelling heat exchange catheter and method of using same

A catheter is adapted to exchange heat with a body fluid, such as blood, flowing in a body conduit, such as a blood vessel. The catheter includes a shaft with a heat exchange region disposed at its distal end. This region may include at least one balloon which is adapted to receive a remotely cooled heat exchange fluid preferably flowing in a direction counter to that of the body fluid. Embodiments including multiple balloons enhance the surface area of contact, and the mixing of both the heat exchange and the body fluid. The catheter can be positioned to produce hypothermia in a selective area of the body without cooling the entire body system. It is of particular advantage in brain surgeries where stroke, trauma or cryogenic tumors can best be addressed under hypothermic conditions.
Owner:ZOLL CIRCULATION +1

Systems and methods for making noninvasive physiological assessments

Systems and methods for assessment of tissue properties, noninvasively, by acquiring data relating to at least one aspect of intrinsic and / or induced tissue displacement, or associated biological responses, are provided. Data relating to tissue displacement and associated biological changes may be acquired by detecting acoustic properties of tissue using ultrasound interrogation pulses, preferably in a scatter or Doppler detection mode. Based on this data, tissue properties are assessed, characterized and monitored. Specific applications for systems and methods of the present invention include non-invasive assessment and monitoring of intracranial pressure (ICP), arterial blood pressure (ABP), CNS autoregulation status, vasospasm, stroke, local edema, infection and vasculitus, as well as diagnosis and monitoring of diseases and conditions that are characterized by physical changes in tissue properties. Methods and systems for localizing physiological condition(s) and / or biological response(s), such as pain, by targeting and selectively probing tissues using the application of focused ultrasound are also provided.
Owner:PHYSIOSONICS

Surgical stapling and cutting instrument with side mounted retraction member

A surgical stapling and severing instrument particularly suited to endoscopic procedures incorporates a handle that produces separate closing and firing motions to actuate an end effector. In particular, the handle produces multiple firing strokes in order to reduce the required amount of force required to fire (i.e., staple and sever) the end effector. A linked transmission reduces the required handle longitudinal length, yet achieves a rigid, strong configuration when straightened for firing. A traction biased firing mechanism avoids binding in driving this straightened linked rack. The instrument further has a manually actuatable retraction system that does not require the use of additional springs or other mechanisms to generate retraction forces which must be overcome when generating the forces necessary to fire the device. In various embodiments, the retraction system provides a visual indication to the surgeon as to how far firing has progressed.
Owner:CILAG GMBH INT

Left atrial appendage devices and methods

Devices and methods for clamping tissue and / or moving two tissue structures together by moving two plates or arm together. The pressure or force applied to the tissue may be used to bring the tissue together, to seal an opening or to cut through and remove a portion of the tissue. In one procedure disclosed, a clip applier may be used to apply one or more clips to the left atrial appendage of the heart to prevent clots from the left atrial appendage from embolizing and causing harm to the patient, such as a stroke.
Owner:ATRICURE

Surgical instrument incorporating EAP blocking lockout mechanism

A surgical stapling and severing instrument particularly suited to endoscopic procedures incorporates a handle that produces separate closing and firing motions to actuate an end effector. The handle produces multiple firing strokes to reduce the required amount of force required to fire (i.e., staple and sever) the end effector. A linked transmission reduces the required handle longitudinal length, yet achieves a rigid, strong configuration when straightened for firing. One or more electrically activated lockout mechanisms, such as electroactive polymer (EAP) actuators, are biased to prevent firing unless activated. One lockout is a spring-biased side pawl firing mechanism enabled by an EAP block actuator. Another is a firing trigger EAP lock. Yet another is a closure yoke EAP lock. Yet a further one is a manual retraction EAP lock that locks the firing mechanism. Thereby, various sensed or commanded inputs may be incorporated to prevent inadvertent firing.
Owner:CILAG GMBH INT

Surgical stapling instrument incorporating a multi-stroke firing mechanism with automatic end of firing travel retraction

A surgical stapling and severing instrument particularly suited to endoscopic procedures incorporates a handle that produces separate closing and firing motions to actuate an end effector. In particular, the handle produces multiple firing strokes in order to reduce the required amount of force required to fire (i.e., staple and sever) the end effector. A linked transmission reduces the required handle longitudinal length, yet achieves a rigid, strong configuration when straightened for firing. A traction biased firing mechanism avoids binding in driving this straightened linked rack in cooperation with an anti-backup mechanism, with a lockout mechanism that prevents releasing the closure trigger during firing. Furthermore, an external indicator gives feedback to the surgeon as to how far firing has progressed, as well as providing a manual retraction capability.
Owner:CILAG GMBH INT

Surgical Band Fluid Media Dispenser

A multiple use fluid dispenser dispenses a flowable material in a precise pattern and quantity with leaking and clogging between dispensing avoided by employing a trigger fired syringe plunger to expel a fixed volume through a band. Between strokes, an advancement knob rotates the band over a distal dispensing tip to a nondispensing location that wipes excess flowable material and seals a dispensing orifice in a fluid conduit. The advancement knob further may rotate the band to a dispensing position wherein a combination of one or more dispensing holes produce a desired pattern and rate of flow with material over the dispensing hole(s) serving to initiate the flowable material, to control placement, serve as a detachable bandage or buttress material, etc.
Owner:ETHICON ENDO SURGERY INC

Surgical stapling instrument having multistroke firing incorporating a traction-biased ratcheting mechanism

A surgical stapling and severing instrument particularly suited to endoscopic procedures incorporates a handle that produces separate closing and firing motions to actuate an end effector. In particular, the handle produces multiple firing strokes in order to reduce the required amount of force required to fire (i.e., staple and sever) the end effector. A linked transmission reduces the required handle longitudinal length, yet achieves a rigid, strong configuration when straightened for firing. A traction biased firing mechanism avoids binding in driving this straightened linked rack in cooperation with an anti-backup mechanism, with a lockout mechanism that prevents releasing the closure trigger during firing. Furthermore, an external indicator gives feedback to the surgeon as to how far firing has progressed, as well as providing a manual retraction capability.
Owner:CILAG GMBH INT

Surgical stapling instrument incorporating an uneven multistroke firing mechanism having a rotary transmission

A surgical stapling and severing instrument particularly suited to endoscopic procedures incorporates a handle that produces separate closing and firing motions to actuate an end effector. In particular, the handle produces multiple firing strokes in order to reduce the required amount of force required to fire (i.e., staple and sever) the end effector. Varying the center of rotation, circumferential length, and depth of cam lobes in a cam disk that interacts with the firing trigger via a drive wedge allows optimization. In particular, mechanical advantages during specific firing strokes mitigates increased force to fire at the end effector, enabling a more uniform tactile force at the firing trigger.
Owner:CILAG GMBH INT

Biopsy apparatus

InactiveUS20050113715A1Eliminate riskMaximizes length and overall size of coreSurgical needlesVaccination/ovulation diagnosticsPneumatic circuitMedicine
A disposable tissue removal device comprises a “tube within a tube” cutting element mounted to a handpiece. The inner cannula of the cutting element defines an inner lumen and terminates in an inwardly beveled, razor-sharp cutting edge. The inner cannula is driven by both a pneumatic rotary motor and a pneumatic reciprocating motor. At the end of its stroke, the inner cannula makes contact with the cutting board to completely sever the tissue. An aspiration vacuum is applied to the inner lumen to aspirate excised tissue through the inner cannula and into a collection trap removably mounted to the handpiece. The rotary and reciprocating motors are hydraulically or pneumatically powered through a foot pedal operated pneumatically circuit. In one embodiment, the cutting element includes a cannula hub that can be connected to a fluid source, such as a valve-controlled saline bag.
Owner:TISSUE EXTRACTION DEVICES
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