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Two-purpose disinfectant for skin and muscous coat, its production

A disinfectant and mucous membrane technology, applied in the direction of active ingredients of iodine compounds, etc., can solve the problems of general bactericidal effect, poor stability, and many foams, and achieve the effect of rapid penetration, stable performance, and strong penetration

Inactive Publication Date: 2005-12-28
SHANGHAI LIKANG DISINFECTION HIGH TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Chlorhexidine-iodine complex aqueous solution has existing products at home and abroad, Chinese Patent Publication No. CN1404811A, CN1126523C, CN1273032A, CN1105385A all have reports, but its foam is many, slippery, poor stability, bactericidal effect is general

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] Add 2 grams of iodine, 40 grams of chlorhexidine acetate, and 0.6 grams of polyhexamethylene guanidine hydrochloride to 60 grams of fatty acid polyethylene glycol ester, heat and mix at 40 ° C for 2 hours, then add 4 grams of azone, 2 grams of phosphoric acid g, 891.4 g of water, and mix to obtain a disinfectant, and the pH is 7.0.

Embodiment 2

[0039] Add 5 g of iodine, 6 g of chlorhexidine acetate, 1 g of polyhexamethylene guanidine hydrochloride, add 40 g of alkylphenol polyoxyethylene ether, heat and mix at 60 ° C for 1 hour, then add 4 g of azone, phosphoric acid 5 grams, 939 grams of water, mix well to get the disinfectant, pH is 6.0.

Embodiment 3

[0041] Add 10 grams of iodine, 10 grams of chlorhexidine glucose, and 5 grams of polyhexamethylene guanidine phosphate to 150 grams of aliphatic amine polyoxyethylene ether, heat at 40°C for 3 hours, and then add 10 grams of propylene glycol and 5 grams of phosphoric acid. Disinfectant is obtained by mixing 810 grams of water, pH is 6.0.

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PUM

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Abstract

A hydrophilic liquid disinfectant for surgical operation, trauma, burn, perineal mucosa, oral mucosa, vaginal mucosa, etc is prepared through adding iodine, chlorhexidine and polyhexamthylene guanidine to non-ionic surfactant, heating, stirring, adding penetrant, phosphoric acid and water, and stirring.

Description

technical field [0001] The invention relates to a disinfectant, in particular to a dual-purpose disinfectant for skin and mucous membranes and a preparation method thereof. Background technique [0002] At present, the commonly used skin and mucous membrane disinfectants at home and abroad are: [0003] Chlorhexidine alcohol disinfectant has been widely used in surgical hand disinfection and debridement disinfection by the international medical community. It is a commonly used disinfectant ingredient in skin and mucous membrane disinfectants all over the world. It is widely used internationally. The skin disinfectants produced by multinational companies such as 3M and Johnson & Johnson are still mainly 0.5% chlorhexidine alcohol preparations. Such products are more irritating and can only be used for the disinfection of normal skin, not for the disinfection of damaged skin and mucous membranes; [0004] Povidone-iodine aqueous solution is also widely produced and sold at h...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K33/18
Inventor 卞雪莲孙文胜张忠敏黄春明
Owner SHANGHAI LIKANG DISINFECTION HIGH TECH
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