The invention provides a marine antifouling coating. The coating comprises a film forming substance, an antifouling agent and a dilute serving as raw material components, wherein the film forming substance is organic silicon modified acrylic resin; and the antifouling agent comprises nano silver, zinc oxide and a pyrithione coordination compound. An environmentally-friendly marine antifouling coating is prepared by taking the organic silicon modified acrylic resin as the film forming substance, a silane coupling agent and polyamide as curing agents and the nano silver, the zinc oxide and the pyrithione coordination compound as composite disinfection anti-alga agents. The organic silicon modified acrylic resin has low surface energy, so that ordinary microorganisms are difficult to be attached to the surface of the resin; simultaneously, the nano silver and the pyrithione coordination compound have good disinfection and bacteriostasis effects and can effectively prevent the adhesion of marine microorganisms. Moreover, the coating provided by the invention does not contain the conventional cuprous oxide and organic tin antifouling agent, so that the environment is protected well.