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33 results about "Collagen biosynthesis" patented technology
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Use of topical arginine to enhance wound healing
InactiveUS20030091601A1Promote wound healingIncrease in collagen depositionBiocideOrganic active ingredientsEmulsionOrnithine aspartate
The present invention relates to the treatment of wounds by the topical administration of arginine or ornithine to wound sites. There is described herein a wound healing enhancing medicinal composition formulated from the amino acid arginine or a by-product thereof. Topical application of the medicinal composition to the wound site enhances wound healing by increasing collagen biosynthesis. A medical composition of the present invention may be administered alone, on dressings, or in combination with common vehicles for topical application including, for example, oil-based emulsions, gels, creams, ointments, and the like.
Owner:ABAT
Composition containing collagen peptide for improving skin care
ActiveCN102131492APrevent agingPrevent photoagingCosmetic preparationsToilet preparationsWrinkle skinVitamin C
The present invention relates to an oral composition for improving skin care, which has the effects of smoothing skin and preventing wrinkles when taking the composition. More specifically, the composition of the present invention further contains one or more components selected from a group comprising elastin proteins, hyaluronic acid, and vitamin C in a collagen peptide. Especially, according to the present invention, the composition containing the collagen peptide, elastin protein, hyaluronic acid and vitamin C together in an optimized ratio does not cause side effects in the human body when taken. In addition, collagen biosynthesis of skin dermis is maximally promoted and the remaining rate in the user's body is very high. Also, the composition has the effects of suppressing wrinkles in the skin, maintaining or improving skin elasticity, and relieving dryness so it is useful as a healthy functional food for improving skin care and preventing skin aging.
Owner:AMOREPACIFIC CORP
Lactic acid bacteria culture of mung bean and the preparation method of the same, and the cosmetic composition comprising the same
InactiveUS20090068150A1Preventing and improving skin senescenceAlleviating and improving skin stimulusCosmetic preparationsOrganic active ingredientsCulture mediumsSenescence
Disclosed is a lactic acid bacteria culture of mung bean obtained by culturing lactic acid bacteria in a culture medium containing mung bean extract. The culture contains the mung bean extract and GABA (ϝ˜ Aminobutyric acid), so that it exhibits effects of promoting collagen synthesis and alleviating inflammation. Accordingly, the cosmetic composition containing the culture can be usefully used as a cosmetic composition for promoting collagen biosynthesis, preventing or improving skin senescence, anti-inflammatory and preventing or improving skin injury.
Owner:DOOSAN CORP +1
Compositions for Improving Skin Conditions Comprising Matrine or Its Oxidized Derivatives
InactiveUS20100099698A1Increase collagen synthesisInhibited collagenase activityCosmetic preparationsBiocideSide effectVitamin A Retinol
The present invention relates to a composition for improving skin conditions comprising matrine and oxymatrine as an active ingredient. Matrine and oxymatrine have lower cytotoxicity than retinol used as anti-wrinkle agents and exhibit the inhibition effect on collagenase activity and promotion effect on collagen biosynthesis at a molecular level, contributing to excellent efficacy in improvement of skin wrinkles. In addition, both matrine and oxymatrine exhibit the inhibition effect on melanin production by inhibiting intracellular tyrosinase activity, the improving effects of UV-induced skin damage and the skin growth promotion or hair loss prevention. Therefore, matrine and oxymatrine have the excellent improvement effects on skin conditions. Furthermore, matrine and oxymatrine have the excellent anti-obesity and anti-oxidation effects. The composition of this invention can be applied to cosmetic, pharmaceutical and food composition having no cytotoxicities and side effects.
Owner:BIOSPECTRUM
Compositions and methods for use against acne-induced inflammation and dermal matrix-degrading enzymes
InactiveUS20060009494A1Reduce and eliminate scarringEliminate inflammatory responseAntibacterial agentsCosmetic preparationsWhole bodyNeutrophil granulocyte
Acne-affected skin has been found to be accompanied by the presence of matrix-degrading enzymes such as MMPs and neutrophil elastase, induction of neutrophils, and a reduction in procollagen biosynthesis. This invention treats scarring and inflammation accompanying acne by administering, topically or systemically, at least one of (i) an inhibitor of the matrix degrading enzymes and (ii) a cytokine inhibitor that alleviates inflammation and thus also alleviate neutrophil infiltration. Alleviating the matrix degradation and renormalizing procollagen biosynthesis allows for reduced inflammation and better natural repair of acne-affected skin. Inhibiting cytokines alleviates induction of MMPs in resident skin cells, and also alleviates inflammation with its concommitant induction of neutrophils from the blood stream bringing MMPs and elastase into the acne lesion. Dimishing the presence of matrix-degrading enzymes in the acne lesion reduces imperfect repair of the skin and thus decreases scarring in acne-affected skin.
Owner:VOORHEES JOHN J +2
Method for monitoring treatment with a parathyroid hormone
InactiveUS20050255537A1Increase stiffnessImprove toughnessOrganic active ingredientsBiocideProcollagen iOsteoblast
The present invention relates to a method for monitoring effects of administration of a parathyroid hormone by determining levels of one or more markers of an activity of this hormone. Suitable markers of bone formation include one or more enzymes indicative of osteoblastic processes of bone formation, preferably bone specific alkaline phosphatase, and / or one or more products of collagen biosynthesis, preferably a procollagen I C-terminal propetide. Suitable markers of bone resorption and turnover include one or more products of collagen degradation, preferably an N-terminal telopeptide (NTX). In addition, methods for concurrently reducing the risk of both vertebral and non-vertebral bone fracture in a male human subject at risk of or having ossteoporosis are also disclosed, involving administration of human parathyroid hormone (amino acid sequence 1-34) without concurrent administration of an antiseropositive agent other than vitamin D or calcium.
Owner:HOCK JANET MARY +1
UVA (> 360-400) and UVB (300-325) specific sunscreens
UVB radiation of about 300-310 nm wavelength and UVA radiation of about 380-390 nm wavelength, each of which exists in solar light, induces MMPs (matrix metalloproteinases) in human skin that degrade the collagen of the dermal matrix. This degradation contributes to photoaging of human skin, which can be prevented by blocking these wavelengths of solar radiation. In contrast, diseases that result in the overproduction of collagen can be treated by exposing the affected with to radiation having wavelengths in those regions, for these wavelengths not only induce MMPs but also inhibit collagen biosynthesis. For lighter skinned people so affected, the UVA wavelengths are preferred because of the reduced amount of erythema, whereas dark skinned people can be treated with the UVB radiation because they generally do not suffer from erythema.
Owner:RGT UNIV OF MICHIGAN
Compositions for reducing UV-induced inhibition of collagen biosynthesis in human skin
Exposure of human skin to ultraviolet (UV) radiation from the sun not only induces the production of enzymes (matrix metalloproteinases) that degrade collagen, but also inhibits the synthesis of new collagen by inhibiting the synthesis of procollagen. This UV-induced inhibition of the synthesis of collagen can be prevented by the topical application of a retinoid or c-JUN inhibitor to the skin prior to exposure to UV radiation.
Owner:RGT UNIV OF MICHIGAN
Composition having effect of improving skin moisturization, removing skin keratin, improving skin elasticity, inhibiting erythema, improving skin wrinkles or improving skin photoaging, containing ionone or salt thereof as active ingredient
InactiveCN109348703AIncrease moisture contentIncrease elasticityCosmetic preparationsToilet preparationsWrinkle skinProcollagen type i n-terminal peptide
The present invention relates to a cosmetic composition, a health functional food composition, a pharmaceutical and a quasi-drug composition having an effect of improving skin wrinkles, improving skinmoisturization, removing skin keratin, improving skin elasticity, improving skin wrinkles, inhibiting erythema or improving skin photoaging, the composition containing ionone or a salt thereof as anactive ingredient. Since the ionone or a salt thereof of the present invention exhibits the activities of increasing skin moisture content, decreasing the amount of evaporation from skin, increasing the amount of procollagen secretion, promoting collagen biosynthesis, inhibiting collagen fiber damage, inhibiting collagen fiber decomposition, inhibiting erythema and inhibiting the thickening of a skin epidermal layer, the ionone or a salt thereof of the present invention can be effectively utilized as materials for functional cosmetics, health functional foods, pharmaceuticals and quasi-drugs,etc. that provide an effect of improving skin moisturization, removing skin keratin, improving skin elasticity, improving skin wrinkles, inhibiting erythema, improving skin wrinkles and / or improving skin photoaging.
Owner:PLANT SENSATION CO LTD
Biopolymer produced by fermenting the extract of soybean with folic acid and a composition containing thereof
ActiveUS20110288025A1Reduce allergic reactionsPromote absorptionCosmetic preparationsBiocideWrinkle skinBiopolymer
Provided are a folyl extract of fermented soybean (EFS) produced by fermenting a culture including a folic acid and soybean extract by using a microorganism, and a composition including the folyl EFS. The folyl EFS has an anti-histamine effect, an anti-allergic effect, a calcium-absorption-promotion effect, a bone-growth-promotion effect, a cell growth promotion effect, a collagen biosynthesis promotion effect, a wrinkle improvement effect, and an UV-induced cell damage inhibition effect. Accordingly, the folyl EFS can be used in a skin external application or cosmetic composition, a health supplement food composition, a feed composition, and a pharmaceutical composition.
Owner:LABIO CO LTD +1
Compositions and methods for use against acne-induced inflammation and dermal matrix-degrading enzymes
InactiveUS7268148B2Reduce and eliminate scarringEliminate inflammatory responseCosmetic preparationsBiocideWhole bodyNeutrophil granulocyte
Acne-affected skin has been found to be accompanied by the presence of matrix-degrading enzymes such as MMPs and neutrophil elastase, induction of neutrophils, and a reduction in procollagen biosynthesis. This invention treats scarring and inflammation accompanying acne by administering, topically or systemically, at least one of (i) an inhibitor of the matrix degrading enzymes and (ii) a cytokine inhibitor that alleviates inflammation and thus also alleviate neutrophil infiltration. Alleviating the matrix degradation and renormalizing procollagen biosynthesis allows for reduced inflammation and better natural repair of acne-affected skin. Inhibiting cytokines alleviates induction of MMPs in resident skin cells, and also alleviates inflammation with its concommitant induction of neutrophils from the blood stream bringing MMPs and elastase into the acne lesion. Dimishing the presence of matrix-degrading enzymes in the acne lesion reduces imperfect repair of the skin and thus decreases scarring in acne-affected skin.
Owner:RGT UNIV OF MICHIGAN
UVA (> 360-400) and UVB (300-325) specific sunscreens
UVB radiation of about 300-310 nm wavelength and UVA radiation of about 380-390 nm wavelength, each of which exists in solar light, induces MMPs (matrix metalloproteinases) in human skin that degrade the collagen of the dermal matrix. This degradation contributes to photoaging of human skin, which can be prevented by blocking these wavelengths of solar radiation. In contrast, diseases that result in the overproduction of collagen can be treated by exposing the affected with to radiation having wavelengths in those regions, for these wavelengths not only induce MMPs but also inhibit collagen biosynthesis. For lighter skinned people so affected, the UVA wavelengths are preferred because of the reduced amount of erythema, whereas dark skinned people can be treated with the UVB radiation because they generally do not suffer from erythema.
Owner:RGT UNIV OF MICHIGAN
Anti-aging composition
ActiveUS10695275B2Improve stabilitySuperior in effect of reducing skin wrinkleCosmetic preparationsAerosol deliveryCollagenanSkin elasticity
Owner:NEOPHARM CO LTD
Anti-wrinkle cosmetic skin composition containing leontopodic acid as an active ingredient
ActiveCN102238935AImprove stabilityPromote absorptionCosmetic preparationsToilet preparationsWrinkle skinBULK ACTIVE INGREDIENT
Disclosed is an anti-wrinkle cosmetic skin composition containing leontopodic acid as an active ingredient, which exhibits improved collagenase expression inhibitory effects, collagen biosynthesis stimulating effects, and anti-wrinkle effects. Further, the present invention discloses an anti-wrinkle cosmetic skin composition which contains leontopodic acid stabilized with a nanoliposome, and which is excellent in formulation stability and transdermal delivery.
Owner:AMOREPACIFIC CORP
Composition for external skin application containing pine knot extract and method for preparation of the same
InactiveCN102105130APrevent agingCosmetic preparationsToilet preparationsAdditive ingredientSkin cell
Disclosed is a composition for external skin application for preventing skin aging comprising pine knot extract as an effective ingredient. The composition prevents and improves winkles through of skin cell proliferation and collagen biosynthesis, and may be widely applied in the field of skin beauty care and cosmetics.
Owner:AMOREPACIFIC CORP
Micromolecular sodium hyaluronate and micromolecular sodium hyaluronate composition for improving skin aging and sensitivity and application of micromolecular sodium hyaluronate and micromolecular sodium hyaluronate composition
The invention provides micromolecular sodium hyaluronate and a micromolecular sodium hyaluronate composition for improving skin aging and sensitivity and application of the micromolecular sodium hyaluronate and the micromolecular sodium hyaluronate composition, and belongs to the technical field of health food. The micromolecular sodium hyaluronate with the average molecular weight of 80KDa-800KDa has the effect of remarkably improving the water content of the skin, and the collagen peptide and the micromolecular sodium hyaluronate are micromolecules and can be easily absorbed by a human body. The composition composed of collagen peptide hydrolysate, micromolecular sodium hyaluronate hydrolysate, elastin, cubilose powder, mangosteen powder, salmon nose cartilage powder, purple chrysanthemum flower powder, astaxanthin, tremella polysaccharide, vitamin C and concentrated fruit juice can improve skin aging and restore skin elasticity, and has the effects of whitening skin and whitening skin. The skin moisture content is increased, the skin moisture evaporation amount is reduced, the pre-collagen secretion amount is increased, the collagen biosynthesis is promoted, and the skin redness and sensitive symptoms are relieved.
Owner:北京姿美堂生物技术股份有限公司
Lactic acid bacteria culture of mung bean and the preparation method of the same, and the cosmetic composition comprising the same
InactiveUS20150044313A1Preventing and improving senescenceAlleviating and improving skinOrganic active ingredientsCosmetic preparationsLactobacillusSkin Injury
Disclosed is a lactic acid bacteria culture of mung bean obtained by culturing lactic acid bacteria in a culture medium containing mung bean extract. The culture contains the mung bean extract and GABA (ϝ Aminobutyric acid), so that it exhibits effects of promoting collagen synthesis and alleviating inflammation. Accordingly, the cosmetic composition containing the culture can be usefully used as a cosmetic composition for promoting collagen biosynthesis, preventing or improving skin senescence, ant i-inflammatory and preventing or improving skin injury.
Owner:DOOSAN CORP +1
Anti-wrinkle cosmetic skin composition containing leontopodic acid as an active ingredient
ActiveCN102238935BImprove stabilityPromote absorptionCosmetic preparationsToilet preparationsOxalateMedicine
The present invention discloses a wrinkle-improving skin cosmetic composition containing leontopodic acid as an active ingredient, which exhibits enhanced collagenase expression inhibition effect, collagen biosynthesis promotion effect, and wrinkle improvement Effect skin cosmetic composition. Also disclosed is a skin cosmetic composition for wrinkle improvement containing edelweiss acid stabilized into nano liposomes, which has excellent dosage form stability and hard skin absorbability.
Owner:AMOREPACIFIC CORP
Composition including ionone or salt thereof as active ingredient and having effect of enhancing skin moisturizing, exfoliating skin, improving skin elasticity, inhibiting erythema, improving skin wrinkles, or alleviating skin photoaging
ActiveUS10137070B2Improve skinIncrease skin elasticityCosmetic preparationsToilet preparationsBULK ACTIVE INGREDIENTSkin elasticity
Owner:BOTANICSENS
Composition for external skin application containing pine knot extract and method for preparation of the same
InactiveUS20110135773A1Prevent skin agingPromote cell proliferationBiocideCosmetic preparationsWrinkle skinAdditive ingredient
Disclosed is a composition for external skin application for preventing skin aging comprising pine knot extract as an effective ingredient. The composition prevents and improves wrinkles through of skin cell proliferation and collagen biosynthesis, and may be widely applied in the field of skin beauty care and cosmetics.
Owner:AMOREPACIFIC CORP
Anti-aging composition containing ginseng-derived exosome-like vesicles as active ingredient
Disclosed in the present specification are: an anti-aging composition containing ginseng-derived exosome-like vesicles as an active ingredient; and a method for preparing the composition. The ginseng-derived exosome-like vesicles can have a diameter of 20 to 500 nm and can be isolated from the roots of ginseng, more particularly, from the juice of the roots of ginseng. The composition exhibits anti-aging effects such as skin wrinkle alleviation, skin elasticity improvement, and collagen biosynthesis promotion by containing ginseng-derived exosome-like vesicles as an active ingredient.
Owner:AMOREPACIFIC CORP
Biopolymer produced by fermenting the extract of soybean with folic acid and a composition containing thereof
ActiveUS8431364B2Promote absorptionPromote biosynthesisBiocideCosmetic preparationsBiopolymerBone growth
Provided are a folyl extract of fermented soybean (EFS) produced by fermenting a culture including a folic acid and soybean extract by using a microorganism, and a composition including the folyl EFS. The folyl EFS has an anti-histamine effect, an anti-allergic effect, a calcium-absorption-promotion effect, a bone-growth-promotion effect, a cell growth promotion effect, a collagen biosynthesis promotion effect, a wrinkle improvement effect, and an UV-induced cell damage inhibition effect. Accordingly, the folyl EFS can be used in a skin external application or cosmetic composition, a health supplement food composition, a feed composition, and a pharmaceutical composition.
Owner:LABIO CO LTD +1
Anti-aging composition
ActiveUS20190125643A1Improve stabilitySuperior in effect of reducing skin wrinkleCosmetic preparationsToilet preparationsMedicineSkin elasticity
The present invention relates to an anti-aging composition. More specifically, the anti-aging composition according to the present invention is highly stable, harmless to the body, and effective in reducing wrinkles and improving elasticity of the skin due to the superb capability for stimulating collagen biosynthesis.
Owner:NEOPHARM CO LTD
Composition including ionone or salt thereof as active ingredient and having effect of enhancing skin moisturizing, exfoliating skin, improving skin elasticity, inhibiting erythema, improving skin wrinkles, or alleviating skin photoaging
ActiveUS20170367954A1Improve skinIncrease skin elasticityCosmetic preparationsToilet preparationsWrinkle skinAdditive ingredient
Provided herein are a cosmetic composition, a health functional food composition, a pharmaceutical composition, and a quasi-drug composition that include ionone or a salt thereof as an active ingredient and have an effect of enhancing skin moisturizing, exfoliating skin, improving skin elasticity, inhibiting erythema, improving skin wrinkles, or alleviating skin photoaging. The ionone or the salt thereof has an activity of enhancing skin moisture content, reducing skin moisture evaporation, increasing procollagen secretion, promoting collagen biosynthesis, suppressing collagen fiber damage, suppressing collagen fiber decomposition, inhibiting erythema, and suppressing the thickening of a skin epidermis layer, and thus may be usefully used as a material of functional cosmetics, health functional foods, pharmaceuticals, quasi-drugs, or the like that provide an effect of enhancing skin moisturizing, exfoliating skin, improving skin elasticity, inhibiting erythema, improving skin wrinkles, and / or alleviating skin photoaging.
Owner:BOTANICSENS
Antiaging composition comprising exosome-like vesicles derived from ginseng
The present specification discloses an anti-aging composition comprising exosome-like vesicles derived from ginseng as an active ingredient and a method for preparing the composition. The ginseng-derived exosome-like vesicles may have a diameter of 20-500 nm, and may be isolated from ginseng roots, more specifically, from the juice of ginseng roots. By including ginseng-derived exosome-like vesicles as an active ingredient, the composition exhibits anti-aging effects such as improving skin wrinkles, enhancing skin elasticity, and promoting collagen biosynthesis.
Owner:AMOREPACIFIC CORP
Cosmetic composition containing oleuropein for strengthening the scalp and improving condition
The present disclosure relates to a cosmetic composition containing oleuropein for strengthening the scalp and improving the condition, the composition affects the hydration and elasticity of the scalp by promoting the biosynthesis of filaggrin and collagen biosynthesis of the scalp, and the composition can strengthen a scalp weakened by environmental factors such as aging and ultraviolet rays, and improve a damaged scalp.
Owner:COSMAX INC
Hydroxamic Acid Derivatives and the Preparation Method Thereof
InactiveUS20080242730A1Avoid expansionCosmetic preparationsBiocideHydroxamic acidBULK ACTIVE INGREDIENT
The present invention provides hydroxamic acid derivatives represented by the formula, having antioxidation, collagen biosynthesis promotion and skin pore contraction effects, and a method for preparation thereof. Further, the present invention provides skin-care external compositions for preventing skin aging, containing said hydroxamic acid derivatives represented by the formula as an active ingredient.
Owner:AMOREPACIFIC CORP
Cosmetic composition comprising extract from mallotus japonicus for improving skin wrinkle
InactiveUS20080206366A1Improve skinEfficient actionBiocideCosmetic preparationsWrinkle skinAdditive ingredient
The present invention relates to compositions for inhibiting elastase activity, enhancing collagen biosynthesis and improving skin wrinkle, comprising Mallotus japonicus extract as active ingredient. The present compositions exhibit the inhibition effect on elastase activity and promotion effect on collagen biosynthesis at a molecular level, and as a result, excellent efficacy in improvement of skin wrinkles.
Owner:COREANA COSMETICS
Anti-aging composition
ActiveUS11446223B2Improve stabilitySuperior in effect of reducing skin wrinkleCosmetic preparationsHair cosmeticsCollagenanSkin elasticity
Owner:NEOPHARM CO LTD
A modified polycarboxylate powder water reducer specially used in fluid mortar
The invention discloses a modified polycarboxylate powder water-reducer specially used in fluid mortar, which comprises the following components in mass percent: 90.0-98.0% of the original powder of polycarboxylate water-reducer; 0.5-98.0% of superfine talc powder 5.0%; anti-adsorption agent 0.25-1.0%; high-viscosity biosynthetic collagen 0.03-0.08%; fibrillar synthetic pulp 0.3-0.5%; high polymerization retarder 0.5-2.0%. Through the above-mentioned method, the modified polycarboxylate powder water-reducer specially used in fluidity mortar provided by the present invention can improve the flow performance of the polycarboxylate water-reducer by means of effective and low-dosage additives through physical compounding , increase the spreading area of the fluid mortar, prolong the release time of the polycarboxylate superplasticizer force, maintain a good construction work degree, improve work efficiency, and improve the construction quality.
Owner:SUZHOU XINGBANG CHEM BUILDING MATERIALS
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