1524 results about "Carnitine" patented technology

Disclosed herein are compositions to meet the needs of aged pets and other animals. Pet foods, pet treats and pet supplements with anti-aging effects are disclosed whose compositions include the R-alpha-lipoic acid in the amount of 0.10 grams to 1.5 grams and L-carnitine in the amount of 0.10 grams to 3 grams in addition to the usual composition. Optionally, coenzyme Q can be added in an amount of at least 1 mg / day. Optionally, creatine can be added in an amount of at least 0.2 grams / day. These additional components fight age-related declines in mitochondrial function, which result in less energy and other signs of aging.

Disclosed herein are compositions to meet the needs of individuals, including humans and pets. Nutritional beverages, powders to make the same, a pudding and a nutritional bar are disclosed whose compositions include the R-alpha-lipoic acid in the amount of 0.12 grams to 1.5 grams and L-carnitine in the amount of 0.12 grams to 3 grams in addition to the usual composition. Optionally, effective amounts of coenzyme Q and / or creatine also are added. These additional components fight age-related declines in mitochondrial function which result in less energy and other signs of aging.

Disclosed herein are methods to treat cognition disorders, particularly those associated with aging. The method comprises administering a combination of a carnitine and an oxidant. Preferably the oxidant is thioctic acid. Preferably 0.12 grams to 3 grams of carnitine (particularly ALC) and 0.12 and 1.5 grams of R-alpha-lipoic acid are administered. Optionally, coenzyme Q and / or creatine also are administered. Preferably 10 mg to 500 mg / day of coenzyme Q10 and 1 to 30 grams / day of creatine are administered. The same method can be used to treat cognition deficits associated with carbon monoxide poisoning, mild traumatic brain injury, Type 2 diabetes mellitus, obsessive-compulsive disorder, environmental toxin exposure, and other conditions.

The present invention relates to a method and transdermal pharmaceutical composition for preventing or reducing the likelihood of calcium deficiency or imbalances caused by calcium deficiency. The transdermal pharmaceutical composition includes a therapeutically effective amount of a pharmaceutically acceptable salt of calcium and a pharmaceutically acceptable carrier constituting a pluronic lecithin organogel. In addition to calcium, the transdermal pharmaceutical composition may also contain a therapeutically effective amount of: (1) a pharmaceutically acceptably salt of other minerals such as magnesium, zinc, selenium, manganese, or chromium; (2) a vitamin such as vitamin A, vitamin D, vitamin C, vitamin E or B-complex vitamins, choline, lecithin, inositol, PABA, biotin, or bioflavomoids; (3) a carotenoid such as lycopene or lutein; (4) a hormone such as dehydroepiandrosterone, progesterone, pregnenolone, or melatonin; (5) an amino acid such as arginine, glutamine, lysine, phenylalanine, tyrosine, GABA, tryptophan, carnitine, or acetyl-l-carnitine; (6) a fatty acid such as a fish oil or flax seed oil; (7) a vita-nutrient such as coenzyme Q10; (8) a cartilage building nutrient such as glucosamine, chondroitin, or MSM, (9) a herb such as ginkgo biloba, echinacea, 5-HTP, St. John's wort, or saw palmetto; or (9) any combination thereof. The transdermal pharmaceutical composition may be topically administered to a human to prevent or reduce the likelihood of calcium deficiency or imbalances caused by calcium deficiency such as hypertension, high cholesterol, colon and rectal cancer, osteomalacia, rickets, osteoporosis, cardiovascular disease, preeclampsia, tooth decay, and premenstrual syndrome.

A method for mimicking the effects of caloric restriction by administration of a food substrate having carnitine or a carnitine derivative and an antioxidant. The food substrate is capable of modulating gene expression in a way similar to caloric restriction.

Disclosed herein are compositions to meet the needs of aged pets and other animals. A pet food formulated for senior pets provides alpha-lipoic acid at about 0.15 to 50 mg / kg body weight / day, carnitine at about 0.5 to 100 mg / kg / day, and optionally coenzyme Q at about 0.01 mg / kg / day and / or creatine at about 15 mg to about 1 g / kg / day. A pet treat for senior pets provides alpha-lipoic acid at about 0.15 to 50 mg / kg body weight / day, carnitine at about 0.5 to 100 mg / kg / day, and optionally coenzyme Q at about 0.01 mg / kg / day and / or creatine at about 15 mg to about 1 g / kg / day. A pet supplement for mature pets offers alpha-lipoic acid at about 0.15 to 50 mg / kg body weight / day, carnitine at about 0.5 to 100 mg / kg / day, and optionally coenzyme Q at about 0.01 mg / kg / day and / or creatine at about 15 mg to about 1 g / kg / day.

The invention discloses a feed additive for improving the stress resistance, meat color and meat quality of a grown fattening pig and application thereof. The feed additive comprises the following components in parts by weight: 0.3-0.5 part of L-carnitine, 10-20 parts of betaine, 10-15 parts of electrolyte, 1-3 parts of selenium preparation, 2-5 parts of iron preparation, 3-5 parts of magnesium preparation, 0.5-1 part of chromium preparation, 1-2 parts of decavitamin, 5-10 parts of compound amino acid, 1-5 parts of tea polyphenol, 5-10 parts of isatis root and 20-61.2 parts of carrier. The feed additive provided by the invention has the following advantages: (1) the feed additive is composed of nutrient substances, Chinese herbal medicines and plant extracts, has non-toxic side effect, and is beneficial for the health of animals and human beings; (2) the raw material used by the invention is stable in resource, low in price, simple in production process, easy for industrial production; and (3) the feed additive provided by the invention can be used for rapidly supplementing various nutritive stress resisting substances, reliefing the stress of animals, improving the meat color and meat quality, and reducing the drip loss.

The invention discloses a formula milk powder for promoting the absorption of fatty acid and calcium and a preparation method thereof. Raw cow milk, lactose, 1,3-Dioleoyl 2-palmitoyl triglyceride and demineralized whey powder as main materials are added with concentrated whey albumen powder, Alpha-lactalbumin powder, oligosaccharide, walnut oil, casein phosphopeptide, docosahexaenoic acid, arachidonic acid, nucleotide, lutein, inositol, carnitine and the like as well as vitamins, mineral substances and other nutrients needed for strengthening infants, and fat humanization, protein humanization and carbohydrate humanization are realized. The powdery product is produced by the processes of blending, homogenization, concentration, spray-drying, packaging and the like. According to the physiological characteristics and nutritional demand of the infants, the invention reinforces the calcium, the 1,3-Dioleoyl 2-palmitoyl triglyceride, other nutrient ingredients and the like, and aiming at the oversea clinical test conclusion of the 1,3-Dioleoyl 2-palmitoyl triglyceride, the final test conclusion of comparison with breast milk and infant formula milk powder sold on the market in the process of a clinical feeding test is that the feeding result of the designed formula approximates the feeding result of the breast milk and is better than the feeding result of an infant formula milk powder group sold on the market.

The invention discloses a meal replacement protein powder solid beverage for managing the body weight and belongs to the field of nutrient foods. The solid beverage comprises the following components of soybean isolated protein, dried skim milk, whey protein concentrate, resistant dextrin, inulin, L-carnitine, a white kidney bean extract, a guarana extract, soy dietary fiber powder, pea fiber, oat fiber, erythritol, stevioside, phospholipid, Arabic gum, xanthan gum, pectin, alkalized cocoa powder, xylooligosaccharide and edible essence. By comprehensively considering the difference of nutrient components required by a human body at daytime and nighttime, the solid beverage disclosed by the invention is reasonable in formula matching and balanced in nutrition, and is the meal replacement solid beverage for supplementing the nutrients of the human body and controlling the body weight; the production process is simple and the drying is avoided; the damage to plant extracts and other components is prevented, so that the effects of nutrient components are guaranteed; besides, no sugar is added in the formula of the meal replacement protein powder solid beverage, so that the meal replacement protein powder solid beverage is suitable for being eaten by people with diabetes.

The invention relates to the field of food drink, in particular to a collagen drink preparation, and aims to overcome the shortcoming of single function of the existing collagen solid drink. The collagen drink preparation comprises the following raw materials: collagen, fructo-oligosaccharide, medicinal and edible extract, food additive, sorbitol and honey, wherein the medicinal and edible extract includes at least two of red date extract, colla corii asini extract, medlar extract, poria cocos extract, lemon extract, lotus leaf extract, hawthorn extract, spina date seed extract and lily extract; the food additive includes any one to three of sweetener, iron supplement, vitamin C, citric acid and L-carnitine; and a preparation method of the collagen drink preparation mainly comprises the steps of: pretreatment, accessory weighing, mixing, drying and sterilizing, soft material preparation, granulation, finishing and the like. The collagen drink preparation provided by the invention can realize the beauty of a skin surface layer and the deep health of an organism, and has the effects of tonifying blood, replenishing qi, improving immunity and moistening intestines to remove toxins.

The invention discloses ugine sport nutrition milk tea powder and a preparation method thereof and belongs to the technical fields of solid drinks, modified milk powder and nutritious foods. The milk tea powder is characterized by comprising whole milk powder, skim milk powder, whey protein powder, collagen powder, soy peptides powder, maize oligopeptide, inulin, maltodextrin, soluble soybean polysaccharide, instant tea powder, phospholipid, L-carnitine, a vitamin premix and a mineral premix. The milk tea powder disclosed by the invention has the advantages of giving a full play to the effects of nutrition complementation and cooperative gain, filling a market vacancy and integrating the functions of supplementing calcium, strengthening bones, losing the weight, relieving fatigues, keeping fit and the like; the milk tea powder is good in taste, convenient to eat, good in safety, strong in acceptability, free of toxic or side effects, simple in production process and easy to product and has a great market development potential.

An orally or parenterally administered composition for reducing the storage of lipids in a human, the composition comprising: an effective amount of hydroxycitric acid; an effective amount of carnitine; an effective amount of biotin; an effective amount of one or more gluconeogenic substrates selected from the group consisting of: aspartate, lactate, glycerol, and a gluconeogenic amino acid or alphaketo analogue thereof; an effective amount of eicosapentanoic acid; and an effective amount of one or more ingredients selected from the group consisting of: medium chain triglycerides (MCT) with fatty acid backbones containing 6 to 14 carbon atoms or their individual fatty acid analogues or metabolic precursors, sesame seeds or derivative products, sesamin and / or its epimer episesamin, caffeine, forskolin, 7-keto dehydroepiandrosterone (7-keto DHEA), green tea extract containing epigallocatechingallate (EGCG), capsaicum, and 5-hydroxytryptophan (5-HTP). The supplement may also be combined with a food, beverage, condiment, spice or salad dressing base to provide a food, beverage, condiment, spice or salad dressing product designed to reduce lipid storage.

The present invention relates to a nutritional supplement composition, comprising a therapeutically effective amounts of Vitamin C, Vitamin D3, Thiamin, Riboflavin, Niacin, Vitamin B6, Folic acid, Vitamin B12, Pantothenic acid, Calcium, Magnesium, Zinc, Chromium, Sugar, Protein, Acetyl-L-Carnitine, Dimethylaminoethanol complex, Phosphatidylserine complex, L-Glutamine, N-Acetyl-L-Tyrosine, L-Phenylalanine, Taurine, Methionine, Valine, Isoleucine, 5 Hydroxytryptophan, L-Taurine, N-Acetyl-Tyrosine, N-Acetyl-L-Cysteine, Alpha Lipoic Acid, Alpha Glycerylphosphoricholine complex, Bacopa Monnieri extract, Gingko Biloba extract, Passion flower, Lemon Balm, Gotu Kola, Ashwagandha, Choline Bitartrate complex, Panax Ginseng extract, Turmeric, Organic freeze dried fruit juice blends (concord grape, red raspberry, pineapple, cranberry, acai, pomegranate, acerola cherry, bilberry, lingonberry, black currant, aronia, sour cherry, black raspberry), Organic freeze dried greens blends (barley grass, broccoli, beet, carrot, alfalfa, oat), and Protein digestive enzyme blends (Protease 4.5, peptidase, bromelain, protease 6.0, protease 3.0, L planatrum, B bifidum) in a mixture to provide optimal cognitive function.

The invention discloses a compound additive for sow which belongs to the animal nutrition technique field. The compound additive bases on high nutrition concentration, colligated balances each nutrition element proportion from in terms of physiology regulation, and regulates the sow milk secretion using natural hormone like substance without hormone negative effect. In addition, the compound additive strengthening adds many nutrition elements, such as L-carnitine which a young pig has less self synthetizing amount and needs out source milk, accordingly, survival rate and weighting rate of the young pig are increased. The compound additive and the clean drinking water with 40 DEG. C are mixed in proportion to 1:20 by weight for confecting water solution which is drunk by sow after eating during the postpartum third day to ablactation freely. The additive can increase nannie sow feed intake, improve astriction, increase quantity of milk yield, improve milk quality and increase ablactation weighting and viability of young pig.

The invention relates to a nutritive defatting food. The nutritive defatting food comprises the following components of whey protein concentrate, hydrolyzed fish collagen protein, soy protein isolate,rice protein, inulin, psyllium husk, resistant dextrin, resistant starch, chenopodium quinoa willd, konjaku flour, chia seeds, fructo-oligosaccharide, xylooligosaccharide, isomaltulose, erythrite, steviosides, linseeds, linseed oil, CMC, medium chain triglyceride, conjugated linoleic acid glycerides, L-carnitine, ferment, complex vitamins, and composite mineral substances. The nutritive defattingfood is good in satiety, balanced in nutrients, and good in defatting effect.

The invention discloses a novel carbonyl reductase, a gene, a mutant thereof, a recombinant expression vector containing the gene and the mutant, a recombinant expression transformant, a recombinase preparation method, and applications of the carbonyl reductase and recombinase to preparation of active chiral alcohols with a chiral carbonyl compound before asymmetrical reduction. The carbonyl reductase is derived from candida glabrata, is applied to preparation of a plurality of optically-active chiral alcohols such as (R)-chloromandelic acid methyl ester, (R)-2-hydroxy-4-phenyl ethyl butyrate, (R)-4-chlorin-3-phenyl ethyl butyrate and the like. Compared with other preparation methods, a product prepared through the method has high concentration, does not require additionally or slightly adding any expensive coenzyme, has high optical purity, and has the advantages of mild reaction conditions, easiness and convenience for operating, easiness for amplifying and the like, and has a good industrial application prospect in the production of clopidogrel, L-carnitine and perindopril antihypertensive medicinal intermediates.

The invention discloses meal replacement powder with balanced nutrients. The meal replacement powder comprises the following components: millet, lotus roots, buckwheat, coix seeds, oat, black kerneled rice, Chinese yam, lotus seeds, yellow corn, potatoes, Chinese chestnuts, black sesame seeds, konjak, fermented black beans, Chinese wolfberry fruits, walnuts, mulberries, red jujubes, radix puerariae, olive oil, perilla seed oil, maltodextrin, whey protein concentrate, L-malic acid, L-carnitine and milk calcium. The invention further discloses a preparation method of the meal replacement powder with balanced nutrients. After the meal replacement powder is eaten for a long term, the effects of controlling postprandial blood sugar, nourishing the liver, nourishing the kidney, protecting heart and cerebral vessels, and recuperating the spleen, the stomach and large intestines can be obtained, and the nutrient and health status of people can be effectively improved and promoted.

The invention relates to a functional mixture for refreshing and remitting the physical fatigue and the visual fatigue and application thereof. The mixture comprises the components such as taurine, caffeine, green tea extract, American ginseng extract, guarana extract, ginkgo leaf extract, wolfberry extract, lutein, L-carnitine, vitamin B1, nuclear yellow acid, nicotinic acid, vitamin, folic acid, vitamin B, vitamin C, auxiliary materials and the like. The mixture can be used for preparing the functional beverage, the effervescent preparation and the solid beverage electuary. The functional mixture has an application mode which is convenient to carry so as to meet the requirement, has the functions of remitting the physical fatigue and the brain fatigue, adds the nutrients for protecting the vision such as the wolfberry extract and the lutein, is particular suitable for personal who operates a computer for a long time, drivers and students, and plays roles in improving the brain power, protecting the vision, and remitting the physical fatigue and the visual fatigue.

The invention discloses a serum-free culture medium for mesenchymal stem cells. The serum-free culture medium for the mesenchymal stem cells comprises the following ingredients: fibronectin at the final concentration of 25mu g / ml, basic fibroblast growth factors at the final concentration of 10ng / ml, human epidermal growth factors at the final concentration of 15ng / ml, recombinant human insulin at the final concentration of 1mg / ml, human transferrin at the final concentration of 0.55mg / ml, human blood albumin in a volume ratio of 5 percent, sodium selenite at the final concentration of 0.67mug / ml, L-carnitine at the final concentration of 5mM and resveratrol at the final concentration of 30mu M. When the mesenchymal stem cells are cultured by the serum-free culture medium for the mesenchymal stem cells, animal-derived serum is not contained, so infection risks can be controlled; the L-carnitine and the resveratrol which are added into the serum-free culture medium for the mesenchymalstem cells can effectively improve the growth state of the mesenchymal stem cells; and the growth speed of the mesenchymal stem cells is remarkably improved, and the biological characteristics of themesenchymal stem cells are kept unchanged.

The invention discloses a weight-loss health-care food which is prepared from the main raw materials of, by weight, 1-60% of a white kidney bean extract, 1-50% of L-malic acid, 1-65% of L-carnitine tartrate, and 1-40% of konjac powder. The invention also discloses a preparation method of the weight-loss health-care food. The method comprises the step that: the main materials of the white kidney bean extract, L-malic acid, L-carnitine tartrate, and konjac powder are well mixed, such that the health-care food with weight-loss function is obtained. With the health-care food, starchy substance absorption is inhibited, body metabolism is promoted, and energy conversion is promoted, such that fat consumption is increased, fat formation is prevented, and a weight-loss function is achieved. With the preparation method, absorption of nutrients such as proteins and vitamins is not influenced, diet control is not needed, and weight can be naturally controlled and reduced. The preparation method provided by the invention has the advantages of simple process, no high-temperature operation, convenient operation, and energy saving.

A dietary supplement system includes a dietary supplement composition for oral administration by an individual in the morning, the composition, including (a) a telomere maintenance complex including: Purslane extract (aerial parts); Turmeric rhizome extract (95% curcuminoids); Quercetin dehydrate, Cayenne pepper fruit; Vanadium (as vanadyl sulfate); Fenugreek seed; Astragalus root extract, Omega fatty acid complex including linoleic acid; alpha-linolenic acid; oleic acid borage seed oil gamma-linolenic acid), evening primrose oil fish body oil (eicosapentaenoic acid; docosahexaenoic acid); (b) a calorie restriction mimetics and gene expression complex including Trans-resveratrol (from Polygonum cuspidatum root extract); Pterostilbene Fisetin 50% (Buxus microphlla Sieb (stem and leaf; Alpha lipoic acid, Coenzyme Q-10, Betaine HCl, Sulfur (from methylsulfonylmethane); L-Carnitine tartrate; L-Carnitine HCl, and (c) a free radical scavenger complex, including Green tea leaf extract catechin and polyphenols); Anthocyanins (from bilberry fruit and grape skin extracts).

The invention provides a feed additive, feed and preparation method thereof for preventing nutritional fatty liver of fish. Optimized compound of choline chloride, bile acid, carnitine, betaine and phospholipids is added into pellet feed for feeding fish, which can obviously reduce the settlement of fat in liver of fish caused by nutrient induction, avoid the generation of fatty liver diseases and promote the healthy growth of fish.

The invention provides an infant milk powder with adjusted structure of aliphatic acid, which comprises the following raw materials (by weight portion in tons): dry matter of fresh milk 276, desalinized whey powder 450, structured fatty oil 105, lactose 50, fructooligosaccharide 20, alpha-lactalbumin 10, docosahexaenoic acid 5, arachidonic acid 6, nucleic acid 0. 42, taurine 0. 45, choline 0. 42, L-carnitine 0. 06, beta-carotene 0. 012, composite vitamin 2. 5, composite microelement 3. 5 and balancing refined vegetable oil.

The invention provides a nutrient composition for augmenting immune strength or physiological detoxification. The nutrient composition consists of an optimal combination of an effective amount of at least one vitamin antioxidant, at least one mineral antioxidant and a highly saturable amount of at least three high potency antioxidants. The at least one vitamin antioxidant can be vitamin C, bioflavonoid complex, vitamin E, vitamin B6 or beta-carotene and the at least one mineral antioxidant can be zinc or selenium. The at least three high potency antioxidants can be alpha lipoic acid, acetyl L-carnitine, N-acetyl-cysteine, co-enzyme Q10 or glutathione. Also provided is a nutrient composition for augmenting immune strength or physiological detoxification that consists of an optimal combination of an effective amount of at least three vitamin antioxidants, at least two mineral antioxidants and a highly saturable amount of at least three high potency antioxidants. Further provided is a method of stimulating immune system function or a method of augmenting a therapeutic treatment of a disease. The method consists of administering to an individual a nutrient composition of the invention one or more times a day over a period of about 5-7 weeks, the immune system function being stimulated to result in an increase of CD4+ cells of at least about 15% compared to pre-administration levels. A method of stimulating a physiological detoxification function of an individual or a method of augmenting a therapeutic treatment of a disease is also provided. The method consists of administering to an individual a nutrient composition of the invention one or more times a day over a period of about 5-7 weeks, the physiological detoxification function being stimulated to result in a decrease of one or more free radical markers by about 20% compared to pre-administration levels.

The invention provides a drink composition containing L-carnitine, plant extracts and water. The plant extracts are selected from barley seedling, barley or fried barley, chrysanthemum, honeysuckle, arabian jasmine flower, tea flower, bamboo leaf flavonoid, eucommia ulmoides male flower, medlar, herba houttuyniae and the like; furthermore, the drink composition also contains inositol, taurine, lysine or lysinate, caffeine, nicotinamide, vitamin B6 and vitamin B12. The invention further provides a preparation method of the drink composition, as well as application of the drink composition in preparation of drinks for supplementing the L-carnitine by oral administration, and burning fat to reduce weight, removing grease and cleansing the palate, clearing away heat and toxic materials, refreshing and relieving summer-heat, refreshing, resisting fatigue, improving appetite and promoting digestion, protecting cardio-cerebral vessels, regulating immunity, resisting fatigue and oxidation, protecting liver and treating fatty liver. According to the novel functional drink containing L-carnitine nutrition and the plant extracts, provided by the invention, the plant extracts and the L-carnitine are matched to realize cooperative nutrient and health functions.

The invention discloses infant formula milk powder added with secretory immunoglobulin A and a preparation method thereof. The infant formula milk powder consists of demineralized whey powder, defatted milk powder, mixed vegetable oil, milk sugar, mineral substance premix, lecithin, arachidonic acid, lactulose, fructooligosaccharides, oligosaccharide, water soluble vitamin premix, secretory immunoglobulin A, calcium hydroxide, citric acid, docosahexenoic acid, milk phosphatide, lactoferrin, soyabean lecithin, liposoluble vitamin premix, nucleotide and L-carnitine. The invention also discloses a method for preparing the infant formula milk powder. The infant formula milk powder has important effects of improving infant immunologic function, preventing allergy and preventing mucous membrane infection. The provided secretory immunoglobulin A fluidized bed low-temperature addition technology contributes to effectively guaranteeing the activity of immunity substances.

The invention provides goat milk powder for an infant. The goat milk powder is prepared from the following raw materials in parts by weight: 18 to 30 parts of skim goat milk powder, 5 to 10 parts of corn syrup solid, 5 to 12 parts of whole goat milk powder, 4 to 8 parts of special grease, 1.0 to 1.6 parts of fructo-oligosaccharide, 1.0 to 1.6 parts of galactooligosaccharide, 10 to 25 parts of vegetable oil, 25 to 40 parts of milk sugar, 14 to 24 parts of concentrated goat whey protein powder, 0.5 to 1.2 parts of alpha-whey protein, 0.2 to 0.4 part of DHA, 0.2 to 0.5 part of arachidonic acid, 0.12 to 0.16 part of vitamin premix, 0.4 to 0.9 part of mineral substance premix, 0.0004 to 0.01 part of L-carnitine, 0.01 to 0.03 part of taurine and 0.02 to 0.04 part of nucleotide, wherein the special grease is triglyceride with the ratio of 50 to 70 percent, on the Sn-2 position, of palmitic acid. According to the goat milk powder provided by the invention, effort is further made for enabling the formula goat milk powder to be more like breast milk, so that the absorption of the infant to nutrients in the milk powder is more comprehensive, and the probability of dyspepsia and easiness in getting inflamed and diarrhea of the infant is further reduced.