97 results about "Defatting" patented technology

The invention relates to a hemostatic medicament, in particular to a soluble hemostatic gauze and a preparation method thereof. The soluble hemostatic gauze contains an absorbent gauze, sodium hydroxide, and sodium carboxymethyl cellulose which is generated by, reaction of chloroactic acid in an alcohol solvent; and the weight ratio of the three raw material components is 1: 1.8: 2.35. The methodfor preparing the soluble hemostatic gauze comprises the following steps of water scrubbing, alkalization, etherification, alcohol washing, neutralization, and drying as well as weighing, cutting, and packaging after a prepared semi-finished product is qualified through the inspection. The soluble hemostatic gauze can be applied to exodontia, dermatological surgery, trauma hemostasis, and wound surface protection.

The invention discloses a dendrobe beauty fluid and a preparation method thereof. The dendrobe beauty fluid comprises a dendrobe extract, a tremella extract and a hydrolysis product of defatted milk, wherein the dendrobe extract is an aqueous extract of the dendrobe; the tremella extract is an aqueous extract of tremella; the hydrolysis product of defatted milk is a product obtained by hydrolyzing defatted milk by trypsin; the ratio of the dendrobe to the tremella to the defatted milk which are taken as raw materials is (1-5g) to (0.3-1g) to (5-12ml). The composition provided by the invention has good whitening, moisturizing and anti-ageing effects on skin to enable the skin to be mild and fine, and full of elasticity and gloss.

A process for preparing the leather from the skin of American frog or bullfrog includes such steps as defatting, expanding in alkali solution removing ash, softening with enzyme, tanning twice, dyeing, and slightly coating for finish which has the procedures of drying in air, natural moistening, beating, stretching, ironing or coating, polishing, and coating oil. Its advantages are high air permeability and water resistance, and good softness.

The invention relates to sutures and in particular relates to a method for preparing an absorbable suture. The method for preparing the absorbable suture disclosed by the invention comprises the following steps: (1) separating protein chorion; (2) purifying collagen fibers; (3) deoiling and degreasing; (4) inactivating viruses; (5) performing chrome tanning; (6) performing crosslinking dehydration; (7) polishing; (8) performing chitosan atomization; and (9) packaging. The absorbable suture prepared by the method disclosed by the invention has the characteristics of high tensile strength, knotting firmness, high biocompatibility and small toxic and side effects, and the suture can be absorbed by the body. The suture is completely absorbed, an absorption reaction is avoided, the suture does not need to be taken out, the tissue compatibility is high, and an adverse reaction in the human body is avoided regardless of the time; and moreover, the surface is smooth, the suture is difficultly infected by germs, and infection can be avoided.

This invention relates to preparations of collagen proteins and collagen peptides. It comprises: 1) mechanically pulverizing alkali leather or raw leather 100, washing at atmosphere and regulating pH 7- 10; 2) adding degreasing enzyme 0.1 - 1.2, stirring for 0.5 - 4 hours at 20 - 45 deg.C, washing; 3) adding surfactant 0.1 - 1.2, stirring for 0.5 - 4 hours at 20 -45 deg.C, washing; 4) adding active biological enzyme 0.1 - 0.8 at 30 - 65 deg.C, degrading for 0.5 - 12 hours; 5) heating to 75 - 90 deg.C for 15 - 30 minutes to inactivating enzyme; 6) filtering and distilling at 40 - 65 deg.C with pressure reduction; and 7) spraying to dry and obtain solid collagen proteins and collagen peptides powders. Owing to alkali degreasing enzyme and surfactant, leather degreasing rate will be up to 95% to produce easily soluble products with low cost and high productivity. The products can be used in skin nourishment and healthy food.

The invention discloses blended non-woven fabric and a preparation technology thereof. The blended non-woven fabric comprises the preparation raw materials of degummed silk protein fiber and degummed natural vegetable fiber, wherein the mass ratio of the degummed silk protein fiber to the degummed natural vegetable fiber is (20:80) to (80:20). The blended non-woven fabric not only has the advantages of softness, skin protection and skin favorableness of silk, but also has the elasticity and water absorption of fiber. The blended non-woven fabric is simple in preparation technology, and can be widely applied to industrials of facial masks, sanitary towels, sanitary pads, paper diapers, cosmetics, respirators, hygienic products and medical supplies.

The invention discloses a fish skin collagen support loading epidermal growth factors and a preparation method thereof. The fish skin collagen support is composed of cross-linked fish skin collagen support bodies and nanometer particles of the load epidermal growth factors. The preparation method comprises the steps that after dewatering, degreasing, enzyme treatment and dialysis is conducted on fish skin, the cross-linked fish skin collagen support bodies are prepared, then the cross-linked fish skin collagen support bodies are soaked in a solution of the nanometer particles of the load epidermal growth factors, and the fish skin collagen support loading the epidermal growth factors is obtained after freezing and drying. The support has a slow releasing effect on the loaded factors, and prolongs the acting time of the epidermal growth factors at a trauma position. The fish skin collagen support obtained through the method has the advantages of being good in biocompatibility and biodegradability, free of immunogenicity and the like, is harmless to a wound surface, can effectively induce wound surface healing and is a good medical material.

The invention discloses a method for preparing donkey skin collagens. In the method, fresh donkey skin is used as a raw material, and modified donkey skin collagen products are modified by steps of unhairing, degreasing, crushing, alkali solution soaking, low-temperature enzymolysis, purification, modification and the like. The donkey skin collagen products prepared by the method is characterized by retaining a triple helical structure, possessing biological activity, being homologous and compatible with human organisms and skin, along with high biological degradability, low antigenicity and the like; and the donkey skin collagens can be diluted by water in any ratio and be used for preparing surgical implants and tissue engineering medical products and developing medicaments, medical preparations, healthcare products and the like.

The invention provides a vaseline oil gauze producing method. The method includes preparing a medical absorbent gauze, vaseline and paraffin oil as raw materials; placing the vaseline and the paraffin oil in proportion into a stainless steel container or a ceramic container to heat and melt, and stirring evenly; sinking the medical absorbent gauze into the heated, melted, diluted and mixed oil; placing the container accommodating the vaseline oil gauze into a dry heat sterilizer to sterilize. The volume proportion of the vaseline and the paraffin oil is 20:1, and weight proportion of the vaseline and the gauze is 2:1. The vaseline oil gauze produced by the method has the advantages of lubricating, anti-adhesion, anti-oxidation and prompting cell growth and wound healing, can be used for covering surgical wounds and wound surfaces, draining wounds and covering normal skin, and plays a role of moisturizing and caring skin, anti-aging for skin cells and the like.

Biogenous artificial bone tissue is set inside the solution of serial surfactants for full wetting and penetration, the solution enters to the bone tissue and the fat tissue falls down to disperse inthe surfactant solution and to be eliminated via water rinsing. The surfactant used may be biodegraded inside body and is non-toxic and harmless. The said process has high defatting effect and efficient antigenicity reducing effect. The processed artificial bone has even high mechanical performance, the production process has no pollution, and the product has no residual toxic matter and is convenient in storing and transportation.

The invention discloses an energy-saving and environment-friendly mink skin tanning method, which comprises the following working procedures of: A) carrying out a soaking working procedure in soaking solution with the solution formula of 25g / L of table salt and 1g / L of soaking enzyme100-c; B) carrying out a degreasing and re-soaking working procedure in degreasing and re-soaking solution with the solution formula of 1ml / L of degreasing agent (Supralan80), 1ml / L of wetter ethanoic acid (HAC) and 0.5ml / L of degreasing enzyme200; C) carrying out a softening and picking working procedure in softening and picking solution with the solution formula of 40g / L of table salt, 2-3ml / L of Super lotan A, 0.5ml / L of Sinxit and 6g / L of glycolic acid; and D) carrying out a tanning working procedure in tanning solution with the solution formula of 40g / L of table salt, 10g / L of aluminite powder (Novaltan Al) and 4-5g / L of Tanning assist B. The energy-saving and environment-friendly mink skin tanning method disclosed by the invention has the advantages of simpleness in manufacturing and processing the mink skin, small water consumption and pollution, and higher energy saving and environment protection effect.

The invention discloses a weakly-acidic high transparent soap which is mainly prepared from amino acid surfactant, humectant, neutralizer and deionized water, wherein the amino acid surfactant comprises glutamic acid surfactant, glycine surfactant and sarcosine surfactant; and based on the total mass of the weakly-acidic high transparent soap, the mass percent of the glutamic acid surfactant is 25-30%, the mass percent of the glycine surfactant is 8-10%, and the mass percent of the sarcosine surfactant is 5-8%. The invention also discloses a preparation method of the transparent soap. The pH value of the weakly-acidic high transparent soap is close to that of the skin; and the weakly-acidic high transparent soap has moderate degreasing power, does not hurt the skin, is easy to foam and can produce abundant foam.

The invention discloses a sterile collagen dressing and a preparation method thereof. The preparation method of the sterile collagen dressing comprises the following steps: degreasing an animal tendon, slicing, disinfecting, smashing, performing acid soluble enzymolysis, centrifuging and removing the precipitate to obtain a collagen stock solution; adjusting the concentration and the viscosity of the collagen stock solution, performing ultrafiltration and purification, and condensing to obtain the collagen solution with high purity and high concentration; performing freeze drying, smashing and performing irradiation sterilization, dosing and filling into an aluminum foil bag containing a non-woven. The activity of the collagen is kept, and the degeneration of the collagen due to the irradiation or the cross-linking reaction can be avoided; the traditional dialysis purification is replaced by the ultrafiltration and purification so that the purifying time is shortened; the traditional semiautomatic operation is replaced by an automatic system, so that the hand pollution is avoided, and the cleanliness, purity and biological activity of the product are guaranteed.

The invention discloses a preparation method of an alginate dressing for stopping bleeding. The preparation method comprises the following steps of placing alginate and pectin into a stirrer according to the part weight, and heating to obtain a mixture I; mixing diatomite, sodium pyrophosphate and sodium polyacrylate, then, heating, preserving heat, cooling and sieving to obtain a mixture II; adding the mixture II into the mixture I, then, adding sorbitol, hyaluronic acid, aminohexanoic acid and linoleic acid, and regulating the pH value after uniformly stirring at room temperature to obtain a mixture III; and soaking absorbent gauze into the mixture III, drying, sealing, packaging and irradiating to obtain the alginate dressing. The dressing prepared by using the preparation method not only has a bacterium inhibiting effect, but also can achieve a bleeding stopping effect so as to be widely applied to clinical treatment.

The invention discloses a composite facial mask nutrient solution. The solution is prepared from, by weight, 8-20 parts of tomatoes, 12-30 parts of cucumbers, 4-10 parts of bitter gourds, 4-8 parts of lemons, 3-6 parts of vitamin A, 2-4 parts of vitamin E, 4-8 parts of olive oil, 0.5-2 parts of hyaluronic acid, 0.5-2 parts of water-soluble collagen, 1-3 parts of pearl powder, 5-10 parts of skim milk, 0.8-1.5 parts of honey, 0.02-0.06 part of ethyl alcohol, 0.05-0.15 parts of sodium citrate and 20-50 parts of deionized water. The provided composite facial mask nutrient solution has no additive, and has no stimulation on the skin, has good functions of detoxifying and beautifying as well as whitening and moisturizing, can effectively clean and lubricate the skin, has a good function of maintaining facial and cervical skin and good effects of removing freckles and wrinkles, has no toxic and side effects, and is worth popularizing.

The invention belongs to the technical field of biological materials of tissue engineering and specifically relates to an artificial skin prepared by collagen and a polymer material through ultrasonic treatment. The preparation method of the artificial skin comprises the following steps of performing washing, cutting, sterilization treatment, degreasing treatment, tissue mashing treatment, acidic enzymolysis, salting-out and dialysis treatment, defoaming treatment, crosslinking treatment, treatment by a modifier, ultrasonic treatment, freeze-drying and vacuum drying on a tendon or dermis tissue. The artificial skin provided by the invention can not only protect a wound as a temporary wound cover for a human body, but also repair the wound by permanently retaining growth of a dermal scaffold, thereby overcoming the shortcomings of expensive price, limited sources, long manufacturing time, short preservation time, injuries to an organism caused by secondary skin grafting and the like of an existing artificial skin product. The product prepared by the preparation method provided by the invention has the advantages of extensive materials, short production cycle, long preservation time and low price, and is suitable for clinical extensive application.

The invention provides a shower cream containing rice vinegar, wherein the raw materials include (by weight percent) potash soap 20-40%, lycine 2-4%, carboxymethyl cellulose 0.5-1.5%, rice vinegar 0.5-1.5%, perfume compound 0.5-1.5%, distilled water 48-68%, preservative agent 0.5-1% and penetrating agent 0.2-1%.

The invention discloses an amino acid transparent soap. The amino acid transparent soap comprise, by mass, 50-55% of sodium lauroyl glutamate, 5-10% of polyol, 2-4% of glucose, 4-8% of ethanol, 0.1-0.5% of D-panthenol, 1-2% of hyaluronic acid, 1-2% of Sophora flavescens root extract, 1-2% of oat starch, 1-2% of yeast extract, 25-40% of deionized water, and triethanolamine for adjusting the pH value, wherein the pH of the transparent soap is 5.1-5.5. The invention also discloses a making method of the amino acid transparent soap. The transparent soap has same acidity to skins, and has he advantages of moderate degreasing, skin-friendly property, no irritation, abundant foams, and skin moistening effect.

The invention discloses an ultrasonic emulsifying degreasing method for an animal skin. The ultrasonic emulsifying degreasing method comprises the steps of: removing impurities on the surface of an animal skin and washing the animal skin through clean water, and cutting the animal skin for later use; adding a surfactant to the animal skin, implementing ultrasonic emulsifying degreasing, rinsing the animal skin by pure water at 29-31 DEG C after the ultrasonic treatment, filtering, and drying to constant weight at 102-104 DEG C to obtain the degreased animal skin. The method disclosed by the invention, in treating a mammal skin or a fishskin, can achieve degreasing rates greater than 68% and 80% respectively, and is low in collagen loss rate, wherein the collagen loss rate of the mammal skin is lower than 10% and the collagen loss rate of the fishskin is lower than 6%; and the degreased animal skin has a high collagen content, and after being further processed, can be widely applied to food, cosmetics, medicine and other fields.

The invention discloses a preparation method of non-denatured collagen from yak skin. The preparation method comprises the following steps: (1) pretreatment; (2) degreasing and impurity removal; (3) acidification and homogenization; (4) enzymolysis; (5) salting-out purification: adding saturated saline to supernatant obtained from step (4), continuously performing stirring until no white flocculesare continuously separated out, and then conducting standing and centrifuging and collecting precipitates; (6) isoelectric point purification: dissolving the precipitates obtained in step (5) with anacetic acid solution, then adjusting the pH of the solution to 6.5-7.0 by using NaOH, conducting standing and centrifuging, and collecting precipitates; (7) desalting; and (8) drying. The method of the present invention overcomes the disadvantages of damage on the triple helix structure of collagen caused by traditional collagen preparation processes. By adopting low-temperature preparation in entire process, the acetic acid, enzymatic hydrolysis, freeze drying and other processes are used to obtain the non-denatured collagen from yak skin. The process of the present invention is simple in operations and capable of achieving large-scale industrial production. The prepared non-denatured collagen from yak skin has good development and utilization prospects in the biomedical fields such as biological dressings and drug delivery carriers.

The invention discloses a method for preparing fishskin source acellular dermal matrix. The method comprises the following steps of (1) fishskin pretreatment; (2) sterilization and disinfection treatment; (3) ungreasing treatment; (4) decoloring treatment; (5) high and low permeability treatment; (6) strong base and ablation treatment, (7) multigelation treatment; and (8) freeze-drying and sizingtreatment. According to the method, osmotic pressure is used to alternatively process lytic cells, at the same time, the combination of strong base ablation and multigelation methods removes cellularconstituents to achieve a more ideal effect of removing cells, the prepared fishskin source acellular dermal matrix has a double-deck structure, the treatment process has little damage on a dermal supporting structure, the integrity of a timbering material can be saved well, and the adhesion and growth of the cells in a later stage is facilitated.

The invention relates to a processing technique of animal fur, in particular to a tanning and dyeing technique of mink skin with functions as fur and leather. The technique comprises the following steps of (1) green hide selection and pre-processing, (2) water soaking, freshness recovery, oil removal and grease removal of green hide, (3) nitrate leaching and degreasing, (4) pickling and softening, (5) aluminum tanning, (6) neutralizing, (7) oil tanning, (8) dry cleaning, milling of leather and arranging, (9) chrome tanning, and (10) buffing and dyeing. According to the technique, the design is reasonable, reasonable pre-processing is conducted on the green hide, the quality of the green hide is improved, the subsequent processing technique is simplified, the number of varieties of reagents used for the technique is decreased, the processing cost is low, the production efficiency is high, the quality of finished mink skin is high, the coat color is bright, and the fur is smooth.

The invention discloses a tanning method in manufacturing a beast stufffed specimen. The tanning method comprises the following steps: removing meat, shaving, degreasing, acidizing for 4-50 hours by using sulfuric-acid pickling liquor with pH of 2-3, degreasing, acidizing for 4-50 hours by using citric-acid pickling liquor with pH of 2-3, neutralizing to enable the pH to be 6-7, immersing into tanning liquor prepared by a skin penetrating agent, ammonium sulfate, sodium chloride and aluminum chloride for 24-72 hours, cleaning and brightening. The tanned skin is complete in lip and tail ends of the four limbs, strong in plasticity, good in quality, easy in operation and available in needed materials, low in price, simple and convenient in operation method, is non-toxic and odorless, is safe and environment-friendly and has wide promotion and application values.

The invention discloses a surgical repair patch as well as a preparation method and application thereof. The preparation method of the surgical repair patch comprises the following steps of taking in-vitro raw material skin, removing hair tissues from the outer surface layer, and removing an epidermal layer and a subcutaneous tissue layer by a mechanical cutting method to obtain a corium layer; soaking the corium layer in a nonionic surfactant solution for degreasing; then, performing soaking treatment in an alkali solution for decellularization; next, performing soaking treatment in an equilibrium buffer solution; and finally, carrying out thermal crosslinking to obtain the surgical repair patch. The preparation method can be applied to preparation of surgical repair patches used in the fields of stomatology, neurosurgery, abdominal wall surgery or gynecology. By adjusting the blade on machinery, the thickness of the corium layer is controlled; and meanwhile, a thermal crosslinking method is adopted, so that the interior of collagen molecules is self-dehydrated to form hydrogen bonds, the stability of the repairing film is improved, and the degradation time is further prolonged.

The invention relates to a collagen multifunctional absorbable medical suture line and a preparation method thereof. The preparation method of the collagen multifunctional absorbable medical suture line comprises the following steps of: (1) compound lipase degreasing; (2) ultrasonic enhanced degreasing; (3) compound catalase decoloration; (4) ultrasonic enhanced decolorization; (5) nano and biological function composite tanning; and (6) drying and sterilization. The collagen multifunctional absorbable medical suture line prepared with the method has the advantages of being high in tensile strength, controllable in absorption time, firm to knot, good in biocompatibility, free of adverse reactions in the human body and lasting in antibacterial performance. According to the preparation method, degreasing and decolorization are performed by using a composite biological enzyme process and an ultrasonic enhanced process, so that the method is environment-friendly and high in degreasing and decolorization efficiency; the tensile strength of the collagen medical suture line is greatly enhanced through nano and biological function composite tanning; the absorption time of the suture line inthe body is controllable; and the collagen medical suture line has the lasting antibacterial performance.

The invention relates to the technical field of food processing, and discloses a method for extracting collagen in a fish skin by low-dose irradiation. Main processes comprise the following steps of making the fish skin into fish-skin minced meat, soaking the fish-skin minced meat in a fishiness removing solution, then making the fish-skin minced meat into fish-skin material liquid, afterwards, adding glyceride hydrolase, a flavor enzyme and a compound catabolic enzyme into the fish-skin material liquid, putting an obtained mixture in a cobalt-60 irradiation field to carry out irradiation, making the irradiated liquid material into a concentrated solution through heating inactivation, filtration, discoloration and concentration, and subjecting the concentrated solution to spray drying to make the collagen. According to the method for extracting the collagen by the low-dose irradiation, which is provided by the invention, through applying the irradiation to the material liquid in enzymolysis and degreasing processes, the enzymolysis rate can be improved; the hydrolyzation time is decreased; the degreasing effect is intensified; the yield and the quality of the collagen are improved; moreover, a microorganism can be effectively killed; the corrosion and deterioration prevention effects of the collagen are promoted; the preservation capacity of the collagen is enhanced; further, the molecular chain of the collagen becomes short; the average molecular weight is 1,500 to 3,500 daltons; the collagen is more suitably absorbed by a human body.

The invention discloses a method for preparing collagen oligopeptide by hydrolyzing animal skin by using bacillus subtilis. The method comprises the following steps: carrying out fermentation cultureon bacillus subtilis to obtain bacillus subtilis fermentation liquor, and hydrolyzing animal skin by using the bacillus subtilis fermentation liquor to obtain the collagen oligopeptide which is smallin molecular weight, high in purity and easy to absorb by a human body. In the method provided by the invention, the pretreatment of the animal skin only needs simple mechanical treatment for removingsurface impurities, and does not need chemical pretreatment for degreasing and removing impure protein by using chemical reagents such as salt, alkali, acid and the like, so that the problem of environmental pollution caused by the use of the chemical reagents in the process of preparing the collagen oligopeptide is avoided; and meanwhile, in the method provided by the invention, expensive commercial protease does not need to be added, so that the production cost is remarkably reduced.

The invention discloses an efficient antibacterial low-irritation handmade soap formula which is characterized by comprising the following components in parts by weight: 100-140 parts of sorbitol, 40-60 parts of propylene glycol, 40-60 parts of sodium laureth sulfate, 80-120 parts of cocamidopropyl dimethylamine ethyl lactone, 50-100 parts of glycerol, 130-190 parts of stearic acid, 40-70 parts oflauric acid, 32 to 37 parts of sodium hydroxide, 100 to 125 parts of water, 18 to 23 parts of sodium citrate; 40 to 60 parts of an alkyl glycoside, 150 to 180 parts of cane sugar; and 1-2 parts of nano liposomal salibact. The handmade soap formula with the antibacterial function has the advantages that experiments show that handmade soap prepared by the handmade soap formula has broad-spectrum antibacterial activity, the antibacterial rate of escherichia coli, staphylococcus aureus and candida albicans reaches 99.99%, and the handmade soap formula has efficient antibacterial activity and cankeep skin moisture and reduce degreasing power and irritation to skin.

The invention provides a shower cream containing rice vinegar, wherein the raw materials include (by weight percent) potash soap 20-40%, lycine 2-4%, carboxymethyl cellulose 0.5-1.5%, rice vinegar 0.5-1.5%, perfume compound 0.5-1.5%, distilled water 48-68%, preservative agent 0.5-1% and penetrating agent 0.2-1%.