66results about How to "Has a hemostatic effect" patented technology

The invention relates to application of aldehyde-modified polysaccharide containing carboxyl to preparing medicines and medical materials for stanching, healing wound, inhibiting bacteria, resisting tumor, promoting tissue adhesion or wound closure. The aldehyde-modified polysaccharide molecule containing carboxyl contains aldehyde groups and carboxyl salt. The aldehyde-modified polysaccharide containing carboxyl contains the aldehyde group in the molecule, thus increasing reactivity of the polysaccharide, inhibiting growth of bacteria, inhibiting growth of tumor cells, having the effects of stanching and promoting tissue adhesion and wound closure, the polysaccharide can be used as a drug carrier material, and the aldehyde group also increases biodegradability of the aldehyde-modified polysaccharide; and the carboxyl salt in the molecule increases hydrophilicity and biocompatibility of the aldehyde-modified polysaccharide, and local acidity is not formed during degradation and absorption in human body, which can increase biocompatibility of the human body, so the aldehyde-modified polysaccharide is applicable to the body surface and the body interior.

The invention relates to a starch composite hemostatic dressing of mesoporous silica microspheres, which adopts a sol-gel method and uses a three-block copolymer pluronic as a template agent to synthesize mesoporous silica microspheres with a pore diameter of about 5 nm. It is compounded with starch to prepare a mesoporous silicon oxide microsphere / starch composite hemostatic dressing, and the hemostatic performance of the composite material is observed through animal experiments. The mesoporous silica microsphere / starch composite material not only has strong water absorption performance, but also has obvious in vitro coagulation performance, which can significantly shorten the partial thromboplastin time and prothrombin time. The mesoporous silica microsphere / starch composite material can prevent the bleeding of the rabbit's back skin and liver injury and shorten the bleeding time, and has obvious hemostatic effect.

The invention belongs to the medicine category, and in particular discloses a mild moxibustion plaster. The mild moxibustion plaster comprises the following components in parts by weight: 40-50 parts of blumea oil, 20-30 parts of indometacin, 30-45 parts of heating element, 5-10 parts of medical rubber and 2-5 parts of back lining cloth, wherein the heating element comprises reduced iron powder, active carbon, saline water and far infrared ceramic powder on a ratio by weight of reduced iron powder to active carbon to saline water to far infrared ceramic powder as (8-14):(3-6):1:(5-8). According to the mild moxibustion plaster disclosed by the invention, the moxibustion method is combined with plasters, so that a mild moxibustion plaster is developed; and the mild moxibustion plaster is used for moxibustion treatment, therefore the disadvantages of inconsistent moxibustion time, less human body absorption and large raw material waste and the like in the conventional moxibustion method are completely overcome.

A non-scar plaster for treating trauma is prepared from water-soluble chitosan (50-80 wt.%) and the extracts of 4 Chinese-medicinal amterials including bletilla tuber, rhubarb, etc. Its extracting process is also disclosed. Its advantages are high curative effect and no residual scar.

The invention belongs to the technical field of high-molecular medical biomaterials and relates to a calcium alginate composite medical surgical dressing and a preparation method thereof. The calcium alginate composite medical surgical dressing comprises an absorption core layer, a contact surface layer and a composite gel coating. The absorption core layer is a glue layer. The contact surface layer comprises chitosan fibers and active carbon fibers by blending. The composite gel coating comprises, by weight, 2-4 parts of sodium alginate, 0.5-1 part of medical glycerin, 2-4 parts of low molecular weight chitosan, 0.5-1 part of borneol and 80-100 parts of purified water. The medical surgical dressing prepared from the natural material and the synthetic high-molecular material has good absorbency, good biocompatibility, good biological activity and good mechanical properties.

The invention relates to a preparation method of microporous polysaccharide microspheres, which is characterized by comprising the following steps: preliminary emulsification, enzymolysis crosslinking, emulsification reaction, washing and refining, homogeneous decoloration and drying and packaging. According to the microporous polysaccharide microspheres prepared by the method provided by the invention, the method is simple and convenient, and the cost is low; the product is elastic spherical particles with tens of thousands of micropores in the surface, and has strong water absorption and a double-hemostasis mechanism as well as excellent safety and exact hemostasis effect.

The invention discloses a preparation method of an alginate dressing for stopping bleeding. The preparation method comprises the following steps of placing alginate and pectin into a stirrer according to the part weight, and heating to obtain a mixture I; mixing diatomite, sodium pyrophosphate and sodium polyacrylate, then, heating, preserving heat, cooling and sieving to obtain a mixture II; adding the mixture II into the mixture I, then, adding sorbitol, hyaluronic acid, aminohexanoic acid and linoleic acid, and regulating the pH value after uniformly stirring at room temperature to obtain a mixture III; and soaking absorbent gauze into the mixture III, drying, sealing, packaging and irradiating to obtain the alginate dressing. The dressing prepared by using the preparation method not only has a bacterium inhibiting effect, but also can achieve a bleeding stopping effect so as to be widely applied to clinical treatment.

The invention belongs to the field of biomedical materials, and particularly relates to hemostatic gel for nursing and a preparation method thereof. Carboxymethyl chitosan and paeoniflorin with a hemostatic effect and antibacterial peptide and zinc oxide with a bacteriostatic effect are used as active ingredients and are matched with gel matrix materials such as phaseolus vulgaris gum, sodium carboxymethyl cellulose and gelatin to prepare the hemostatic gel for nursing. The hemostatic gel for nursing has a good sealing effect on wounds, can quickly activate blood platelets, enables blood to becoagulated in a short time, and has a very good hemostatic effect and a very good wound infection prevention effect. The hemostatic gel for nursing is suitable for various types of patients, can meetthe requirements of different clinical scenes, and has positive clinical medical significance.

The invention belongs to the technical field of non-woven fabric, and particularly relates to sepiolite functional non-woven fabric and a preparation method and application thereof. The sepiolite functional non-woven fabric is prepared from the following raw materials in parts by weight: 90-110 parts of fiber non-woven fabric, 30-50 parts of a carrier, 1-6 parts of nano-silica particles and 1-6 parts of chitosan; the carrier comprises attapulgite, activated sepiolite fiber, diatomite and a polyester amide compound, and the weight part ratio of the attapulgite, the activated sepiolite fibers, the diatomite to the polyester amide compound is 1: (1-3): (1-2): (0.5-2). By regulating and controlling the proportion of the carrier and other components, the defect that an existing non-woven fabricslurry coating is poor in air permeability or low in oxygen permeability on the basis that non-woven fabric has antibacterial, deodorizing and moisture absorption properties is effectively overcome,the functional non-woven fabric which is high in air permeability and oxygen permeability is prepared, high quality of the functional non-woven fabric is achieved, and the functional non-woven fabriccan be applied to medical cloth, surgical drapes, nursing pads, gypsum linings, outer fixed support linings and splint linings effectively, and the functional non-woven fabric is also suitable for being used in operation sterile towels, bed sheets, diapers and sanitary towels.

The invention relates to the field of medicine preparation, particularly to dental ulcer gargle and a preparation method thereof. The dental ulcer gargle is prepared by mixing the following components: maltodextrin, sodium carboxymethylcellulose, Carbomer, trisodium citrate, saccharin sodium salt, sodium chloride, potassium hydroxide and purified water. The dental ulcer gargle has the benefits that the dental ulcer gargle does not have toxic and side effects on surface wounds of oral mucosa and is non-irritant. With secretion and neutralization of saliva, the dental ulcer gargle in an oral cavity is changed into hydrogel flooding the whole oral cavity, so that a protective membrane is formed on the surface of a dental ulcer, physically covering the wound and relieving the pain caused by the dental ulcer, oral inflammation and tiny wounds caused by dental hoops or false teeth; meanwhile, the hydrogel further has a certain effect of stopping bleeding.

A cleaning agent for oral cavity is prepared from chitosan and natural hydroxy apatite through dissolving chitosan in acetic acid, proportionally adding hydroxy apatite, stirring, and adding adhesive, humectant, antiseptic, slow releasing agent, flavouring and water.

The invention provides a method for extracting small molecule active peptide from fish skin and application thereof, and relates to the field of small molecule peptide extraction. The method for extracting the small molecule active peptide from the fish skin comprises the following steps of 1, pretreatment of the fish skin; 2, extraction of collagen in the fish skin; 3, separation and purification of fish skin collagen; 4, preparation of collagen polypeptide through hydrolysis; and 5, decomposition of the polypeptide into small molecule peptide. The collagen is extracted from the fish skin and then the small molecule peptide is extracted; the small molecule peptide can adjust the immunocompetence of the human body and activate cell functions, has a certain hemostatic effect, and has a certain relieving effect on pains of joints, muscles and bones and the like; and the collagen polypeptide has a beautifying effect, can be developed into a polypeptide food with the beautifying effect, and also has multiple functions of preventing anemia, promoting mineral absorption, losing weight and the like.

The invention relates to a high-efficiency absorption hemostatic dressing and a preparation method thereof, and belongs to the technical field of medical consumables. The high-efficiency absorption hemostatic dressing of the invention includes a hemostatic layer, an absorption core layer, an antibacterial layer, a waterproof layer and a bottom layer in order. Preparation raw materials of the absorption core layer include fluff pulp and super absorbent resin. The absorption core layer of the invention adopts an absorption structure composed of the super absorbent resin and the fluff pulp, and so a large amount of blood can be quickly and fully absorbed and effectively coagulated without leaking back, thereby ensuring anti-seepage and anti-leakage. Meanwhile, the high-efficiency absorption hemostatic dressing has waterproof, breathable, antibacterial and hemostatic effects, promotes rapid healing of wounds, and is widely used in patients with moderate and severe bleeding.

The invention discloses a hemostasis dressing which comprises zeolite and a medicinal auxiliary material, wherein the ratio of zeolite to the medicinal auxiliary material is (1-20):1; the particle size of zeolite is 0.1-0.6 mm; the medicinal auxiliary material is at least one of povidone K30, povidone K90, starch, dextrin, polyethylene glycol, pregelatinized starch, arabic gum, carbomer 974P and sodium alginate. The medicinal auxiliary material used in the hemostasis dressing is relatively good in water absorbing function and can cooperate with zeolite for stop bleeding, and gel can be generated after the auxiliary material absorbs water and can be adhered to zeolite powder, so that a protecting layer can be formed on a wound surface; the auxiliary material can be absorbed by a user, and healing of wound can be promoted.

The invention belongs to the technical field of biomedical materials, and particularly relates to a plugging anti-adhesion membrane material and a preparation method thereof. According to the preparation method of the plugging anti-adhesion membrane material, provided by the invention, direct coating is combined, direct forming is realized, the forming method is simple, and the selected materials are safe, nontoxic and degradable materials, so that a guarantee is provided for the safety of the prepared plugging anti-adhesion membrane material. The endothelial cells play an important role in the aspects of anticoagulation, cell proliferation regulation and thrombus formation inhibition, anti-adhesion material surface endothelial cellularization can be achieved, thrombus formation and platelet activation can be reduced, and the obvious influence on material blood compatibility improvement is achieved. According to the plugging anti-adhesion membrane material, the degradation time of the hemostatic gel on the outer layer is different from that of the endothelialization electrostatic spinning anti-adhesion membrane on the inner layer, the hemostatic effect in the early stage is achieved, the anti-adhesion effect in the later stage is achieved, and clinical requirements are met.

The invention discloses a nanometer compound nutrient solution preparation special for broiler chicken and a preparation method thereof. The nanometer compound nutrient solution disclosed by the invention contains 3%-15% of vitamins, 1%-8% of amino acid, 1%-6% of nucleotide, 1%-3% of prebiotics, 6%-30% of surfactant, 2%-12% of cosurfactant, 0.1%-0.5% of anti-bacteria preservative and the balance of purified water. A nanometer technology is adopted for compounding the nutrient substances, such as, vitamins, amino acid, nucleotide and prebiotics into a nanometer emulsion according to the requirement of the broiler chicken for the nutrient substances and the nanometer emulsion is a safe, efficient, stable and quality-controllable compound nutrient nanometer emulsion special for broiler chicken. The compound nutrient solution disclosed by the invention can improve the water solubility, dispersity and absorption rate of the nutrient substances, such as vitamins, and can thoroughly solve the problem of bioavailability of the nutrient substances, such as, lipid-soluble vitamins. A nutrition enriched solution which can be highly absorbed and utilized is supplied for the broiler chicken.

The invention relates to the field of medical dressing materials, and particularly relates to a method of preparing a hemostatic dressing by using hydrogel. When in preparation of the hydrogel, orangepeels are boiled to passivate pectinase activity, pectin is extracted through an acid method, methoxyl is removed through strong base so as to form degreased pectin, then amino and carboxyl in adipoyl dihydrazide and the like are used to perform dehydration-condensation reaction so as to form amido bonds to obtain the hydrogel preventing breaking; a cross-linking agent improves the cross-linkingdensity of molecular chains, medicinal auxiliary materials are absorbed by a user so as to add nutrition to tissues of the wound, increase cell activity, provide energy for cell division activity andimprove the healing speed, the anticoagulant property of sodium heparin can prevent the wound from bonding with the hemostatic dressing, preventing flowing blood from solidifying and allowing the blood to be adsorbed at a faster speed, the cross-linking agent, the medicinal auxiliary materials and the sodium heparin are combined to stop excessive bleeding. The hemostatic dressing prepared by the method has good hemostatic performance, can better stop bleeding for a long time, and has high adsorbability, thereby being a safe and efficient hemostatic dressing and being worth promoting and using.

The invention relates to a traditional Chinese medicine composition for treating infantile anal fissure and application thereof. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 1 part of watermelon peel, 1 part of pomegranate bark, 1 part of Chinese waxgourd peel, 1 part of sugarcane peel and 3 parts of honey. The invention also discloses application of the traditional Chinese medicine composition in preparation of a medicine for treating infantile anal fissure. The traditional Chinese medicine composition has the advantages that the composition has the effects of relieving pain, diminishing inflammation, stopping bleeding and promoting wound healing when being used for treating infantile anal fissure. Moreover, the adopted medicinal materials are edible medicinal materials, side effects are avoided due to external application, the traditional Chinese medicine composition is safe and reliable and takes both inside and outside into consideration, the method is easily accepted, the operation is simple, the price is low, the curative effect is obvious, and the advantages of simplicity, convenience, low price and effectiveness of traditional Chinese medicine are fully reflected.

The present invention relates to a kind of medicine composition, Xuening dripping pill, with functions of arresting bleeding and for auxiliary treatment of hemophilia, thromboctopenia, purpura, nosebleeding, etc. The present invention has high bioavailability, fast medicine release, fast acting, high effective content, taking convenience and low cost, and the production process has no pollution. The Xuening dripping pill is prepared with peanut coat as one kind of Chinese medicinal material and medicine carrier as matrix.

The invention discloses a preparation method of a degradable medical bacteriostatic biological film with a bleeding-stopping function, and belongs to the technical field of medical films. The preparation method comprises the following steps of firstly, using shrimp shells and crab shells as raw materials to prepare chitosan fiber; using gamma-polyglutamic acid, n-butyl bromide, allyl bromide, tetrahydrofuran and the like as the raw materials to prepare a hydrogel; mixing the chitosan fiber and the hydrogel to react, thus the active groups at the surface of the chitosan fiber and the active groups at the surface of the hydrogel can produce hydrogen bond attraction force, and the chitosan fiber and the hydrogel are combined together, so as to obtain the modified hydrogel; putting the modified hydrogel into a high-pressure electrostatic spinning device, so as to obtain a composite nanometer fiber film; treating the composite nanometer fiber film in a hot press way, so as to obtain the degradable medical bacteriostatic biological film with the bleeding-stopping function. The degradable medical bacteriostatic biological film with the bleeding-stopping function has the advantages that the degrading time is short, the bleeding stopping time is greatly shortened, the good bleeding-stopping effect is realized, and the bacteriostatic effect on escherichia coli, staphylococcus aureus andcandida albicans is realized; the application prospect is broad.

The invention relates to a sunscreen cream containing a sarcandra glabra fluid extract. Each part of sunscreen cream contains the following components: 8-10 percent of setanol and octadecanol, 4.5-5 percent of white oil No.26, 4.5-4.8 percent of isopropyl palmitate, 1.5-2 percent of simethicone, 2.5-3.5 percent of monobutyl ester, 0.5-0.8 percent of lanoline, 0.5-0.7 percent of polyethylene glycol-6000, 4-5 percent of glycerol, 0.5-0.6 percent of sarcandra glabra fluid extract, 2.5-2.7 percent of phospholipids quaternary amide positive ion emulsifying agent, 0.2 percent of essence and the balance of water. The sunscreen cream can be directly applied to the easily exposed parts, such as the facial part, the neck part or the hand parts, and the like, is fresh and cool without sticky feeling, and can effectively absorb ultraviolet rays, resist aging, prevent the tanning and sunburn of the skin, and effectively prevent water and sweat.

The invention discloses a preparation method and application of haemocoagulase of Agkistrodon akistrodon. It comprises steps of dissolving snake venom, low-temperature centrifugation, dialysis, DEAE-Sepharose FF chromatography, dialysis, DEAE-Sepharose FF chromatography and Sephadex G25 chromatography. It is isolated and purified from the venom of Agkistrodon akistrodon, which is unique to China. It is composed of two subunits, A and B, and has the effect of promoting blood coagulation and hemostasis. The molecular weights of the two subunits A and B are 15.0KD and 14.2KD. The amino acid sequence from the first to the 25th position of the N-terminal of the A subunit is DCSSGWSSYEGHCYKVFKQSKTWTA, and the amino acid sequence from the first to the 25th position of the N-terminal of the B subunit is DCPSDWSSYECHCYKPDEPKTWEDA. Agkistrodon haemocoagulase can be used for clinical hemostasis of various types of bleeding in humans.

The present invention relates to a pregnant woman after-meal fruit-flavor mouth rinse and a preparation method thereof, wherein the raw materials comprise, by weight, 30-50 parts of red halloysite, 20-40 parts of cuttlefish bone, 0-0.3 part of caulis akebiae, 10-15 parts of hydrogen peroxide with a concentration of 30%, 1-4 parts of edible salt, and 25-45 parts of a fruit juice. The preparation method comprises: a, grinding red halloysite; b, grinding cuttlefish bone; c, soaking caulis akebiae for 30 min, boiling for 20-40 min, and taking the drug juice for spare; and d, carrying out mixing stirring on the products prepared in the steps a, b and c, hydrogen peroxide, edible salt and a fruit juice, and screening with a 18-20 mesh sieve to obtain the product mouth rinse. According to the present invention, the advantages of reasonable formula, simple process, low cost and easy mouth rinse carrying are provided; and after pregnant women eat something, the pregnant women can directly use the mouth rinse to rinse the mouth and clean the teeth so as to avoid the growth of bacteria.

The invention provides a traditional Chinese medicinal composition for treating postpartum lochiorrhea of sow, and relates to the technical field of traditional Chinese medicinal herbs. The composition is prepared from the following raw medicinal materials in parts by weight: 25-35 parts of Chinese angelica, 25-35 parts of ligusticum wallichii, 25-35 parts of raw pollen typhae, 15-25 parts of raw trogopterus dung, 5-15 parts of codonopsis pilosula, 5-15 parts of fructus aurantii, 55-65 parts of motherwort, 10-20 parts of raw hawthorn, 2-4 parts of sodium sulfate, 2-4 parts of rhizoma acori graminei, 3-5 parts of common andrographis herb, 1-3 parts of semen strychni and 1-3 parts of eclipta alba. The traditional Chinese medicinal composition has the characteristics of easily available materials, simple preparation, low cost, good practicality and the like, has the effects of nourishing yin and activating blood, removing stasis and promoting tissue regeneration, stimulating uterus, facilitating uterine contraction and reinforcement and increasing discharge of lochia, and has a certain hemostatic effect.

The invention belongs to the technical field of livestock breeding, and discloses fast-grown chicken complete feed, and a preparation method and application thereof. The compound feed comprises the following raw materials: corn flour, fish meal, soybean meal, soybean oil, calcium hydrophosphate, mountain flour, bentonite, trace elements, table salt, vitamins and compound Chinese herbal medicines, wherein the compound Chinese herbal medicines adopt ramulus uncariae cum uncis, herba ecliptae and sanguisorba radix. The fast-grown chicken complete feed uses the compound Chinese herbal medicines to lower the burst rate of Eimeria, reduce the hazard of enteritis, lower a chicken flock death rate, improve a finished product chicken market-appearing rate and shorten a breeding period, a livestock farm obtains a higher profit, in addition, utilization of medicines can be reduced, and the fast-grown chicken complete feed conforms to the requirements of healthy culture and green culture.

The invention discloses a natural ultra-micro calcium oral spray to solve the problem that an oral spray in the prior art takes effect by covering one smell with another, is high in sugar content, and cannot achieve an aim of purifying an oral cavity fundamentally. The natural ultra-micro calcium oral spray consists of ultra-micro calcium powder and auxiliary materials, wherein the weight percentage of the ultra-micro calcium powder is 0.5-1%, and the auxiliary materials include a corrigent, an absorption enhancer, a bacteria remover, a deodorant and a solvent; the weight percentage of the corrigent is 1-5%, the weight percentage of the absorption enhancer is 0.5-2%, the weight percentage of the bacteria remover is 2-5%, the weight percentage of the deodorant is 0.2-0.5%, the solvent is pure water, and the weight percentage of the solvent is 90-95%. In the formula, the selected ultra-micro calcium powder has the effects of clearing away heat and toxic materials, astringing sores and stopping bleeding, activating cells, and killing bacteria, a honeysuckle extract can effectively kill microorganisms to treat oral ulcers, and paeonol can relieve swelling and pain, prevent dental caries, cover up halitosis, clean oral cavity and the like.

The invention relates to the technical field of food preparation, in particular to a preparation method of sand pot local chicken soup. The preparation method has the advantages that healthy raw material chicken are selected, thereby reducing the adverse effects on the human body after eating, improving the smoothness and deliciousness of the soup, reducing the oil content in the soup, and improving the people's favorite degree for the soup. The preparation method of the sand pot local chicken soup comprises the following steps of (1) selection of the raw material, wherein a free-ranging hen growing for 11 months and in the egg-laying period are selected as a raw food material; (2) pretreatment of the raw material; (3) cleaning of chicken nuggets; (4) preparation of auxiliary materials; (5) blanching of the chicken nuggets; (6) preliminary cooking; (7) removal of slag and blood foam; (8) fire regulating for cooking, wherein after removal of the slag is completed, the medium flame is regulated for continuous cooking, when turbidity occurs again on the surface of the soup, step (7) is repeated until the blood foam and slag are no longer produced; (9) addition of chicken blood; (10) removal of slag; (11) dishing up, wherein cooking is continued for 2 min, 5 g of salt is added, the soup is covered with a sand pot cover, the heat is turned off, and dishing up is carried out.

The invention discloses a composite fruit juice black tea beverage and a preparation method thereof. 1 liter of the prepared composite fruit juice black tea beverage is prepared from, by weight, 1-3 gof lime juice, 3-6 g of concentrated peach juice, 5-10 g of concentrated apple juice, 1-3 g of black tea, 50-100 g of high fructose syrup, 20-50 g of glucose, 0.2-0.4 g of potassium sorbate, 0.2-0.6g of citric acid, 0.1-0.3 g of malic acid and the balance pure water. The prepared composite fruit juice black tea beverage contains not only fruit juice fragrance but also tea fragrance and is appropriately sweet, fresh, comfortable, diversified in taste and abundant in efficacy.

A medicine for treating tinea pedis by immersing feet in it is prepared proportionally from pueraria root and alue. Its preparing process is also disclosed.