2472 results about "Isopropyl" patented technology

An environmentally clean dual fuel for an internal combustion engine, comprising acetylene as a primary fuel and a combustible fuel, such as one or more fluids selected from an alcohol such as ethanol, methanol or any other alcohol or alcohols from the group comprising C1-C20 carbon chains, ethers such as from the group comprising dimethyl ether, diethyl ether, methyl t-butyl ether, ethyl t-butyl ether, t-amyl methyl ether, di-isopropyl ether and the like, low-molecular-weight esters such as from the group comprising methyl formate, methyl acetate, ethyl acetate, methyl propionate, ethyl propionate and the like, or other suitable combustible fluid such as mineral spirits and the like, as a secondary fuel for operatively preventing early ignition and knock arising from the primary fuel. The dual fuel, internal combustion system, which generally utilizes a two-stage process for start-up and operation and can be operated with air- or liquid-cooling, is environmentally clean with hydrocarbon, CO, NOx, and SOx emissions substantially eliminated.

Pesticidal compositions containing a pesticidally acceptable carrier, at least one isopropyl-containing compound as a pesticidally active ingredient, and methods for using same, are disclosed.

Compounds of Formula I, and their N-oxides and agriculturally suitable salts, are disclosed which are useful for controlling undesired vegetation wherein R1 is cyclopropyl optionally substituted with 1-5 R5, isopropyl optionally substituted with 1-5 R6, or phenyl optionally substituted with 1-3 R7; R2 is ((O)jC(R15)(R16))kR; R is CO2H or a herbicidally effective derivative of CO2H; R3 is halogen, cyano, nitro, OR20, SR21 or N(R22)R23; R4 is —N(R24)R25 or —NO2; j is 0 or 1; and k is 0 or 1; provided that when k is 0, then j is 0; and R5, R6, R7, R15, R16, R20, R21, R22, R23, R24 and R25 are as defined in the disclosure. Also disclosed are compositions comprising the compounds of Formula I and a method for controlling undesired vegetation which involves contacting the vegetation or its environment with an effective amount of a compound of Formula I. Also disclosed are compositions comprising a compound of Formula I and at least one additional active ingredient selected from the group consisting of an other herbicide and a herbicide safener.

The invention relates to an ethylene oligomerization catalyst composition and an application thereof. The composition comprises the following components: a component a contains chromium acetylacetonate, tetrahydrofuran chromium chloride and / or chromium 2-ethylhexanoate; in the formula of a component b, R1, R2, R3 and R4 are phenyl, benzyl or naphthyl; and R5 is isopropyl, butyl, cyclopropyl, cyclopentyl, cyclohexyl or fluorenyl; a component c contains methyl aluminoxane, ethyl aluminoxane, propyl aluminoxane and / or butyl aluminoxane; a component d has a formula X1R6X2, wherein X1 and X2 are F, Cl, Br, I or alkoxy, and R6 is alkyl or aryl; in the formula of a component e, R is a linking group and selected from alkyl and derivatives thereof as well as aryl and derivatives thereof; and the molar ratio is 1: (0.5-10): (50-3000): (0.5-10): (0.5-10). The catalyst has the catalytic activity being more than 5.0*10<6>g mol<-1>Cr.h<-1>, and the mass of 1-hexene and 1-octylene is more than 93%.

The present invention provides a compound of the formula: wherein ring A is an optionally substituted 5 to 10-membered aromatic ring; R1 and R2 are the same or different and each is an optionally substituted hydrocarbon group or an optionally substituted heterocyclic group; X is a bond and the like; and L is a divalent hydrocarbon group, and a salt thereof, except 3-(aminomethyl)-2,6,7-trimethyl-4-phenyl-1(2H)-isoquinolinone, 3-(aminomethyl)-2-methyl-4-phenyl-1(2H)-isoquinolinone, 3-(aminomethyl)-6-chloro-2-methyl-4-phenyl-1(2H)-isoquinolinone and 3-(aminomethyl)-2-isopropyl-4-phenyl-1(2H)-isoquinolinone. The compound shows a superior peptidase-inhibitory activity and is useful as an agent for the prophylaxis or treatment of diabetes and the like.

The present invention provides methods for the chemical synthesis of nucleosides and derivatives thereof, including 2′-amino, 2′-N-phthaloyl, 2′-O-methyl, 2′-0-silyl, 2′-O-triisopropylsilyloxymethyl, 2′-OH nucleosides, C-nucleosides, nucleoside phosphoramidites, C-nucleoside phosphoramidites, and non-nucleoside derivatives.

The present invention relates to sensitive nanometer polymer material, and is especially nanometer N-isopropyl acrylamide aquogel with both pH and temperature sensitivity and its preparation process. The nanometer N-isopropyl acrylamide aquogel has granularity of 30-200 nm and lowest critical solution temperature (LCST) of 35-45 deg.c. The preparation process of the present invention can regulate the granularity and LCST flexibly.

The invention relates to the technical field of preparation of environment functional materials, in particular to a magnetic composite material surface imprinting thermosensitive adsorbent, and a preparation method and the application thereof. The method comprises the following steps that: firstly, a ferroferric oxide / nerchinskite nanotube magnetic composite material is prepared by a solvent thermal synthesis method; secondly, the magnetic composite material is modified on ethenyl by using 3-(methacrylo) propyltrimethoxyl silane; and finally, the nerchinskite nanotube magnetic composite material is prepared by using the ethenyl-modified magnetic composite material as a substrate material, 2, 4, 5-trichlorophenol as a template molecule, methacrylate as a functional monomer, N-isopropylacrylamide as a thermosensitive functional monomer, ethylene glycol dimethacrylate as a cross-linking agent, and 2,2'-azodiisobutyronitrile as an initiator. The prepared thermosensitive imprinting adsorbent is obvious in thermal stability and magnetic stability, sensitive in magnetic effect and thermosensitive effect, relatively high in adsorption capacity, obvious in reversible absorption / release function along with temperature and obvious in tertiary calcium phosphate (TCP) molecule recognition performance.

A polishing composition which achieves surfaces with high planarity and the reduction of corrosions in the wiring metal surface at the same time is provided.Such compositions include(A) an oxidizing agent;(B) at least one acid selected from an amino acid, a carboxylic acid of no more than 8 carbon atoms, and an inorganic acid;(C) a sulfonic acid having a concentration of 0.01% by mass or more and having an alkyl group of 8 or more carbon atoms;(D) a fatty acid having a concentration of 0.001% by mass or more and having an alkyl group of 8 or more carbon atoms; and(E) at least one compound selected from a pyridine carbonyl compound, a nonionic water-soluble polymer, 2-pyrrolidone, N-methylpyrrolidone, 1,3-dimethyl-2-imidazolidinone, gramine, adenine, N,N′-diisopropylethylenediamine, N,N′-bis(2-hydroxyethyl)ethylenediamine, N,N′-dibenzylethylenediamine, and N,N′-diphenylethylenediamine.

Described herein are precursors and methods for forming silicon-containing films. In one aspect, there is provided an aza-polysilane precursor comprising at least two Si—N bonds, at least one Si—Si bond, and at least two SiH2 groups represented by the following Formula IA, IB and IC:wherein R1 and R2 are independently selected from a linear or branched C1 to C10 alkyl group, a linear or branched C3 to C10 alkenyl group, a linear or branched C3 to C10 alkynyl group, C3 to C10 cyclic alkyl group, C3 to C10 hetero-cyclic alkyl group, a C5 to C10 aryl group, and a C3 to C10 hetero-aryl group, a C2 to C10 dialkylamino group, a C3 to C10 cyclic alkylamino group; R3 and R4 are independently selected from hydrogen, a linear or branched C1 to C10 alkyl group, a linear or branched C2 to C10 alkenyl group, a linear or branched C2 to C10 alkynyl group, C3 to C10 cyclic alkyl group, C3 to C10 hetero-cyclic alkyl group, a C5 to C10 aryl group, and a C3 to C10 hetero-aryl group, a C2 to C10 dialkylamino group, a C3 to C10 cyclic alkylamino group; wherein R1 in Formula IA cannot both be methyl, R1 and R2 in Formula IB cannot both be iso-propyl, tert-butyl, and bezenyl and R3 and R4 cannot both be methyl and phenyl.

A fruit juice-containing food product containing following components (a) and (b) in addition to a fruit component and a base having sweetness; and a method for reinforcing a flavor of a fruit juice-containing food product. (a) one or more refreshing feeling substances selected from the group consisting of menthol, menthone, camphor, pulegol, isopulegol, pulegone, cineol, mint oil, peppermint oil, spearmint oil, eucalyptus oil, and fractions there of. (b) one or more cool feeling substances selected from the group consisting of 3-1-menthoxypropane-1,2-diol, N-ethyl-p-menthane-3-carboxamide, 3-1-menthoxy-2-methylpropane-1,2-diol, p-menthane-3,8-diol, 2-1-menthoxyethane-1-ol, 3-1-menthoxypropane-1-ol, 4-1-menthoxybutane-1-ol, cyclic carboxamides, acyclic carboxamides,N,2,3-trimethyl-2-isopropyl butanamide, a menthoxy alkanol (alkyl group having 2 to 6 carbons), a menthoxy alkyl ether (alkyl group having 1 to 6 carbons), and a menthoxy alkanediol (alkyl group having 3 to 6 carbons).

The present invention relates to a cost effective and industrially advantageous process for the preparation of 4-4(fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulphonylamino)-5-pyrimidinecarboxaldehyde, referred to here as pyrimidine aldehyde of structural Formula I and to the use of this compound as intermediate for the preparation of rosuvastatin.

Imidazolium salts are the immediate precursors to N-heterocyclic carbenes (NHC) yet a simple, general synthetic route to a wide variety of imidazolium salts is not yet available. Such a straightforward route is described for two specific members of this family of ligand precursor: 1,3-Bis(2,4,6-trimethylphenyl)imidazolium chloride (IMes.HCl) and 1,3-Bis(2,6-diispropylphenyl)imidazolium chloride (IPr.HCl). The procedure appears general and similar protocols can be used to isolate various imidazolium salts.

The invention discloses a method for floating high-sulfur gold-bearing copper ore, which aims at solving the problems that the existing beneficiation method is lower in copper and gold recovery rate under high-alkali condition, and problems that xanthate and black powder are adopted as high-sulfur gold-bearing copper ore collecting agents, the collecting power is stronger, the selectivity is poor, the separation difficulty of copper and sulfur can be aggravated and the consumption of inhibitors is increased. The method comprises the steps of by adopting lime and sodium metabisulfite as an ore pulp pH regulator and a pyrite inhibitor, and the mixture of isopropyl xanthogen propionitrile ester, black powder acid and ethyl dithiocarboxyl propionitrile ester according to certain proportion as a collecting foaming agent, carrying out ore grinding, rough concentration, primary scavenging, secondary scavenging, primary concentration, and secondary concentration on a crude ore, thus realizing the high-efficiency recovery on copper and gold in the high-sulfur gold-bearing copper ore. According to the method, through reasonable combination and addition of medicaments, the selective adsorption of the collecting agent on target mineral-copper pyrite and other copper sulfide minerals and gold minerals can be reinforced, and the copper recovery rate and the gold recovery rate can be improved.

The present invention relates to a catalyst composition for ethylene oligomerization and the use thereof. Such catalyst composition includes chromium compound, ligand containing P and N, activator and accelerator; wherein the chromium compound is selected from the group consisting of acetyl acetone chromium, THF-chromium chloride and Cr(2-ethylhecanoate)3; general formula of the ligand containing P and N is shown as:in which R1, R2, R3 and R4 are phenyl, benzyl, or naphthyl. R5 is isopropyl, butyl, cyclopropyl, cyclopentyl, cyclohexyl or fluorenyl; the activatior is methyl aluminoxane, ethyl aluminoxane, propyl aluminoxane and / or butyl aluminoxane; the accelerator is selected from the group consisting of 1,1,2,2,-tetrachloroethane, 1,1,2,2-tetrabromoethane, 1,1,2,2-tetrafluoroethane, and compounds having a formula of X1R6X2, in which X1 and X2 are F, Cl, Br, I or alkoxyl, R6 is alkylene or arylene group; the molar ratio of chromium compound, ligand containing P and N, activator and accelerator is 1:0.5˜10:50˜3000:0.5˜10. After mixing the four components mentioned previously under nitrogen atmosphere for 10 minutes, they are incorporated to the reactor, or these four components are incorporated directly into the reactor. Then ethylene is introduced for oligomerization. Such catalyst can be used in producing 1-octene through ethylene oligomerization. It is advantageous in high catalysing activity, high 1-octene selectivity, etc. The catalytic activity is more than 1.0×106 g product·ma−1 Cr·h−1, the fraction of C8 linear α-olefin is more than 70% by mass.

The invention discloses a nano particle compound and a preparation process thereof. The nano particle compound which is provided by the invention is formed by aquogel microsphere and inorganic nano particles, wherein the inorganic nano particles are jogged in the aquogel microsphere, the aquogel microsphere is isopropyl acrylamide and acroleic acid copolymer aquogel microsphere. The preparation process of nano particle compound comprises following steps that firstly preparing isopropyl acrylamide and acroleic acid copolymer aquogel microsphere, and dispersing aquogel microsphere into water, and dispersing inorganic nano particles into water, secondly mixing two kinds water solution which are obtained in first step, wherein the mass ratio of isopropyl acrylamide and acroleic acid copolymer aquogel microsphere and inorganic nano particle in mixing solution is 1:10-1:20, stirring mixing solution for 5-10 minutes under the conditions of temperature is 25-35 DEG C, and pH is 5-7, thereby obtaining nano particle compound.

Provided herein are methods for treating sickle cell disease, comprising administering to a subject 2-hydroxy-6-((2-(1-isopropyl-1H-pyrazol-5-yl)pyridin-3-yl)-methoxy)benzaldehyde (Compound 1), or a polymorph thereof, in certain dosing regimens.

The invention discloses a magnetic PAFs solid-phase extracting agent. A preparation method of the magnetic PAFs solid-phase extracting agent includes allowing 3-aminopropyl triethoxy silylation ferroferric oxide to have a temperature-programmed reaction with piperazine and cyanuric chloride in the presence of N, N-diisopropylethylamine to obtain the magnetic PAFs solid-phase extracting agent. The magnetic PAFs solid-phase extracting agent and the preparation method thereof have the advantages that the prepared magnetic PAFs solid-phase extracting agent is good in dispersity and stable in core-shell structure; the preparation method is simple, low in cost, widely applicable, capable of achieving repeated material recycling, and the like; a covalent organic framework bonded to the ferroferric oxide can provide various action sites such as an inclusion interaction site, a hydrogen-bond interaction site, a pi-pi interaction site and an anion exchange site, so that the covalent organic framework has specific recognition and retention acting force on polar substances such as phenols and carboxylic acids.

The present invention is directed to novel methods for production of 5-epi-β-vetivone, 2-isopropyl-6,10-dimethyl-spiro[4.5]deca-2,6-dien-8-one and 2-isopropyl-6,10-dimethyl-spiro[4.5]deca-1,6-dien-8-one, which are useful for their fragrant qualities. In one embodiment the present invention describes a method for production of 5-epi-β-vetivone by the use of premnaspirodiene as starting material. In another embodiment the present invention describes a method for production of 2-isopropyl-6,10-dimethyl-spiro[4.5]deca-2,6-dien-8-one and 2-isopropyl-6,10-dimethyl-spiro[4.5]deca-1,6-dien-8-one by the use of premnaspirodiene as starting material. In yet another embodiment the present invention describes a novel method for production of premnaspirodiene from a terpene substrate. Use of the fragrant components or any composition containing the component can be advantageously employed in the perfumery industry.

An internal combustion engine adapted to use an environmentally clean multi-fuel composition, comprising acetylene as a primary fuel and a combustible fuel, such as one or more fluids selected from an alcohol such as ethanol, methanol or any other alcohol or alcohols from the group comprising C1-C12 carbon chains, ethers such as from the group comprising dimethyl ether, diethyl ether, methyl t-butyl ether, ethyl t-butyl ether, t-amyl methyl ether, di-isopropyl ether and the like, low-molecular-weight esters such as from the group comprising methyl formate, methyl acetate, ethyl acetate, methyl propionate, ethyl propionate, ethyl malate, butyl malate, and the like, or other suitable combustible fluid such as mineral spirits and the like, as a secondary fuel for operatively preventing early ignition and knock arising from the primary fuel.

The invention relates to sulfonyl-containing 3,4-diaryl-3-pyrrolin-2-ones compounds having formula (I) wherein R1 is selected from the group consisting of 4-methylsulfonyl, 4-aminosulfonyl, hydrogen, 2-, 3-, or 4-halogen, C1-C6-alkyl, cyclopentyl, cyclohexyl, C1-C4-alkoxy, hydroxy, cyano, nitro, amino or trifluoromethyl; R2 is selected from the group consisting of 4-methylsulfonyl, 4-aminosulfonyl, hydrogen, 2-, 3-, or 4-halogen, C1-C6-alkyl, cyclopentyl, cyclohexyl, C1-C4-alkoxy, hydroxy, cyano, nitro, amino or trifluoromethyl; and R3 is selected from the group consisting of hydrogen, methyl, ethyl, n-propyl, i-propyl, c-propyl, n-butyl, isobutyl; provided that when R1 is a methylsulfonyl or aminosulfonyl group, R2 is any group as defined above except a methylsulfonyl or aminosulfonyl group; and when R2 is a methylsulfonyl or aminosulfonyl group, R1 is any group as defined above except a methylsulfonyl or aminosulfonyl group, also to processes for the preparation of such compounds, to pharmaceutical compositions containing such compounds, and to the medical use of such compounds in the treatment of diseases relating to the inhibition of cyclooxygenase-2 (COX-2).

A cooling topical cosmetic or dermatological preparation which comprises (1R,2S,5R)-2-isopropyl-5-methyl-N-(2-(pyridin-2-yl)ethyl)cyclohexane carboxamide and / or (1R,2S,5R)-N-(4-cyanomethyl-phenyl)-2-isopropyl-5-methylcyclohexane carboxamide, in combination with menthoxypropanediol.

Thermogelling polymers are described containing poly (n-isopropyl acrylamide). Solutions of this polymer, copolymers or mixtures of the polymer with a second polymer such as poly(ethylene glycol), poly (vinyl pyrrolidone) or poly(vinyl alcohol) are liquids at room temperature and solids at body temperature. Thus, also provided are methods of implanting a hydrogel into a mammal by injecting the solution as a liquid at a temperature below body temperature into a selected site in the mammal at a temperature below body temperature, which then undergoes thermal phase transition to form a solid hydrogel in situ in the body as the implant warms to body temperature. Methods for using these thermal gelling materials in various applications including nucleus pulposus replacement / augmentation, wound care, disk replacement, cartilage replacement, joint replacement, surgical barriers, gastrointestinal devices, cosmetic and reconstructive surgery, and breast enlargement are also provided.

The present invention provides aqueous pharmaceutical compositions containing a lipophilic therapeutic agent. In particular, the invention provides aqueous pharmaceutical compositions containing the compound 2,6-diisopropylphenol (propofol). Preferred compositions of the invention contain propofol in the presence of at least one block copolymer (for example, P188 or another poloxamer) and a polyethylene glycol (PEG). Compositions of the invention are preferably sterile or are readily sterilized (e.g., by autoclaving) and are suitable for parenteral administration to any animal, including humans. The compositions are also chemically and physically stable over a wide range of environmental conditions and for extended periods of time.

The invention discloses a temperature-sensitive magnetic sulfadimidine molecular imprinted adsorbent as well as a preparation method and application thereof, belonging to the technical field of preparation of environment functional materials. A gamma-Fe2O3 / SiO2 magnetic composite material is prepared by using a sol-gel method and is subjected to vinyl modification by using 3-(methylacryloyloxy) trimethoxypropylsilane; with a vinyl-modified magnetic composite material (MPS (Modified Polystyrene)-gamma-Fe2O3 / SiO2) as a substrate material, sulfadimidine as a template molecule, acrylamide as a functional monomer, N-isopropylacrylamide as a temperature-sensitive monomer, ethylene glycol-bis(methylacrylic acid) ester as a cross-linking agent and 2,2'-azobisisobutyronitrile as an initiator, a temperature-sensitive magnetic molecular imprinted polymer is prepared by using a free group polymerization process and is applied to selective recognition and separation of the sulfadimidine in an aqueous solution; and the obtained polymer has the advantages of remarkable heat and magnet stability, sensitive magnet and heat inducting effect, higher adsorption capacity, reversible adsorption / release function along with the temperature and remarkable recognition performance of a sulfadimidine molecule.

The invention discloses a preparation method of a double-sensitivity cyclodextrin supermolecule aggregate, belonging to the technical field of functional materials. The preparation method comprises the following steps of preparing a host molecule-photosensitive 4-hydroxycinnamic acid-cyclodextrin (4HCA-CD) by using 4-hydroxycinnamic acid (4HCA) to modify beta-cyclodextrin (beta-CD); using trithioester with adamantine (AD) at tail end as a chain transfer agent, and preparing temperature-sensitive object polymer-double-arm adamantine-poly(N-isopropyl acrylamide)-adamantine (AD-PNIPAM-AD) by using a reversible addition-fragmentation chain transfer free radical polymerization (RAFT) method; constructing a double-sensitivity supermolecule inclusion complex 4HCA-CD / AD-PNIPAM-AD by utilizing comprehensive performance of a beta-CD dewatering cavity and AD; and self-assembling the 4HCA-CD / AD-PNIPAM-AD to form the supermolecule aggregate which is capable of realizing reversible conversion in shape and size by changing light and temperature. The supermolecule aggregate prepared by the preparation method disclosed by the invention has good light / temperature double sensitivities and is capable of carrying out smart response onto external stimulus, so that the supermolecule aggregate has a wide application prospect in the fields of drug loading, controlled release, and the like.

Middle distillate fuel composition is provided containing (a) a middle distillate base fuel, in particular a diesel base fuel, and (b) a Fischer-Tropsch derived paraffinic base oil component with a viscosity of at least 8 mm2 / s at 100° C. In component (b), the ratio of the percentage of epsilon methylene carbon atoms to the percentage of isopropyl carbon atoms is suitably 8.2 or below. Its pour point may be −30° C. or lower. Also disclosed is the use of a Fischer-Tropsch derived paraffinic heavy base oil in a middle distillate fuel composition, for the purpose of improving the cold flow properties of the composition and / or for reducing the concentration of a cold flow or flow improver additive in the composition.

The invention discloses a method for preparing a hollow silica nanosphere by one step. The method comprises the following steps: mixing a poly-N-isopropyl acrylamide aqueous solution and an ethyl orthosilicate prehydrolysis solution at a temperature of 40 to 60 DEG C to react at a constant temperature for 160 to 180 hours; and carrying out ethanol washing, ultrasonic concussion, centrifugal separation and drying on a reaction liquid, and then obtaining the hollow silica nanosphere. The hollow silica nanosphere has a hollow core and mesoporous shell structure, the particle diameter is between 200 and 600 nm, and the shell thickness is between 30 and 100 nm. The invention also discloses the hollow silica nanosphere and the application. The method does not need to use an organic solvent to catalyze or further remove a template agent by high-temperature calcination or chemical corrosion, and can control the hollow nanosphere size and the shell thickness by simply changing the reaction temperature, the reaction time and the feed ratio.

The invention relates to a preparation method of a semi-interpenetrating network nanocomposite hydrogel which can respond to variations in temperature, pH and ultraviolet to realize volume transition. The preparation method of the gel is as follows: taking temperature-sensitive monomers, namely N-isopropylacrylamide and azo type water soluble monomers, namely 4-((4-acryloxy) phenyl azo) benzoic acid as copolymerization monomers, taking modified nano-clay as a cross-linking agent, dissolving the monomers and the cross-linking agent in a cellulose type macromolecular water solution, uniformly stirring, and then performing oxidation, reduction and catalytic free radical polymerization in an ice bath under the protection of nitrogen for preparation. The gel uses nano-laponite cross-linked monomers to constitute a framework of the gel and takes cellulose type macromolecules as semi-interpenetrating macromolecules. The obtained hydrogel has the advantages of excellent mechanical properties, high swelling rate and fast and controllable stimulus response. The gel has the potential to be applied to the field of sustained release of medicaments.