145 results about "Nanoparticle Complex" patented technology

The invention discloses a large-scale preparation method of a transparent super-hydrophobic / super-amphiphobic coating. The method comprises the steps of ultrasonically dispersing nano particles into an alcohol-water mixed system and carrying out hydrolysis and condensation reaction on the nano particles and fluoride-free or fluorine-containing organosilane under the acid or alkali catalysis action to prepare a transparent suspension liquid of a fluoride-free or fluorine-containing organosilane polymer-nano particle compound; and applying the transparent suspension liquid of the compound on the surface of a substrate material through spraying or dip-coating to obtain the transparent super-hydrophobic / super-amphiphobic coating with good performance. Preparation of the transparent super-hydrophobic / super-amphiphobic coating of 10-100m<2> can be completed within an hour; large-scale preparation of the large-area transparent super-hydrophobic / super-amphiphobic coating is achieved for the first time; the preparation method is low in cost and simple in process; and the prepared coating has excellent super-hydrophobic or super-amphiphobic property, relatively good mechanical stability, chemical stability and environment stability, and has a wide application prospect.

Provided are a charge trap memory device including a substrate and a gate structure including a charge trapping layer formed of a composite of nanoparticles, and a method of manufacturing the charge trap memory device.

A fibronectin type III (FN3) domain-nanoparticle or direct conjugate complex containing a polynucleotide molecule, a toxin, polynucleotide molecule or other pharmaceutically active payload is obtained by panning an FN3 domain library with a protein or nucleotide of interest, recovering the FN3 domain and conjugating the FN3 domain with a toxin or nanoparticle containing an active polynucleotide, such as an ASO or siRNA molecule. A fibronectin type III (FN3) domain-nucleic acid conjugate is obtained by panning an FN3 domain library with a protein or nucleotide of interest, recovering the FN3 domain and conjugating the FN3 domain to a nucleic acid (e.g., ASO or siRNA). The nanoparticle complex, nucleic acid conjugate or FN3 domain toxin conjugate may be used in the treatment of diseases and conditions, for example, oncology or auto-immune indications.

A rapid method for the separation of nanoparticles having as few as one ligand attached thereto has been developed. The method relies on the size exclusion separation of a population of nanoparticle-ligand complexes having a narrow uniform size distribution. Ligands are typically biopolymers, functionalized to bind to other nanoparticles for the construction of geometric nanostructures.

It is provided a Near Infrared Sensitive (NIR-sensitive) nanoparticle complex comprising a NIR-sensitive nanoparticle and surfactant(s) adsorbed on the nanoparticle, wherein the surfactant is at least one surfactant selected from:wherein X=1-9; Y=0-9; n=0-9; Z=1-9; W=0-9; m=0-9; each of R1, R2, R3 and R4, if present, is H, substituted or unsubstituted C1-C6 alkyl, substituted or unsubstituted C1-C6 aryl, HS, COOH, NH2 or OH; R5 is COOH, NH2 or OH; with the proviso that n+m is <10;(b) an amino acid having the structure in (a), wherein X=1; Y=2; Z=1; W=1; R1, R2 and R4 are not present; R3 is NH2; and R5 is COOH; or (c) a peptide, wherein the peptide comprise at least one amino acid (b). Further, it is provided a NIR-sensitive nanoparticle complex(es) having biomolecule(s), for example drug(s), loaded on the surfactant(s).

The invention discloses a carbon nanotube-thionine / gold nanoparticle composite material and a preparation method thereof. According to the carbon nanotube-thionine / gold nanoparticle composite material, acidified cut short carbon nanotubes and thionine are used as raw materials, and a carbon nanotube-thionine composite with high loading of thionine electrical signal molecules is prepared; and a ternary nanocomposite is prepared by using the carbon nanotube-thionine composite as a support matrix and micro-gold nanoparticles reduced by Au-N and Au-S bonding. The composite material has high conductivity, small gold particle size, uniform dispersion, large specific surface area and high adhesion ability on a substrate. The preparation method of the carbon nanotube-thionine / gold nanoparticle composite material is simple, convenient and easy to operate. The composite material can be used as sensitive electrical signal probes for immunosensors and DNA sensors.

The invention discloses a preparation method of fluorescent golden nanometer particle protected by stable organic monolayer. The preparation method is that: chloric acid water solution is mixed with sodium citrate, and then the mixture is subjected to reduction reaction with sodium borohydride to generate the hydrosol of the golden nanometer particle stabilized by citric acid; with the assistant of ethanol, N, N'dialkyl-dithio formic acid alkyl fluorene with fluorescent group moves the golden nanometer particle to organic phase so as to form the fluorescent golden nanometer particle compound protected by organic monocular. The preparation method is characterized by easy obtaining of the raw materials, simple technique, no need of heating, high efficiency and quickness, and high productivity, etc. The prepared golden nanometer particle compound has small particle diameter (4-30nm) and even distribution; through coordination adsorption of sulfur atoms in carbon-sulfur dual bonds on the surface of the golden nanometer particle, the golden nanometer particle can be steadily dispersed into a plurality of polarity and nonpolarity organic solvents; proved by experiment, the synthetical golden nanometer particle has very strong fluorescent property, thereby the golden nanometer particle has wide application prospect on the fields of nanometer electron, optoelectronic devices, optics, magnetism material, etc.