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666 results about "Chromatography" patented technology
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Chromatography is a laboratory technique for the separation of a mixture. The mixture is dissolved in a fluid called the mobile phase, which carries it through a structure holding another material called the stationary phase. The various constituents of the mixture travel at different speeds, causing them to separate. The separation is based on differential partitioning between the mobile and stationary phases. Subtle differences in a compound's partition coefficient result in differential retention on the stationary phase and thus affect the separation.
Process for the preparation of a desired erythropoietin glyco-isoform profile
InactiveUS20050153879A1High and uniform product specificityImprove product qualityPeptide/protein ingredientsComponent separationFiltrationRed blood cell
The present invention provides a process for the production of erythropoietin (EPO) with high purity and with a desired profile of EPO glycol-isoforms by using a combination of specific chromatographic steps in such a manner that the starting EPO glycol-isoform profile is changed or modified. The applied chromatographic steps includes at least (a) dye affinity chromatography, and (b) hydrophobic chromatography and / or (c) anion-exchange chromatography. In a preferred embodiment, the process further includes (d) gel filtration chromatography. The present invention also provides a process for the determination of erythropoietin (EPO) glycol-isoform profile in an EPO containing composition.
Owner:SVETINA MONICA +4
High yield method of producing pure rebaudioside A
ActiveUS20060083838A1Reduction in yieldQuality improvementSugar derivativesMetabolism disorderSolubilityAdditive ingredient
The invention provides a high throughput, high purity, high yield system and method of isolating and purifying rebaudioside A (“Reb A”), with acceptable water solubility for all commercial uses, from commercially available Stevia rebaudiana starting material. The invention also provides a means of maximizing yields of 99+% purity Reb A based on the attributes of a given batch of Stevia starting material. The Reb A produced by the invention is water soluble, devoid of bitterness heretofore associated with rebaudioside sweeteners, non-caloric, and suitable for use as a reagent and as an ingredient in orally consumed products, e.g., as a sweetener, flavor enhancer, and flavor modifier.
Owner:SWEET GREEN FIELDS INT CO LTD
Process for producing ethanol
InactiveUS20060019360A1High carbon yieldHigh protein concentrationOrganic compound preparationChemical industryAcetic acidHydrogenation reaction
A process for producing ethanol including a combination of biochemical and synthetic conversions results in high yield ethanol production with concurrent production of high value coproducts. An acetic acid intermediate is produced from carbohydrates, such as corn, using enzymatic milling and fermentation steps, followed by conversion of the acetic acid into ethanol using esterification and hydrogenation reactions. Coproducts can include corn oil, and high protein animal feed containing the biomass produced in the fermentation.
Owner:ZEACHEM
Methods for cleaning industrial equipment with pre-treatment
InactiveUS20080105282A1The result is validHigh degree of softeningSurface-active detergent compositionsNon-surface-active detergent compositionsAdditive ingredientIndustrial equipment
A method of cleaning equipment such as heat exchangers, evaporators, tanks and other industrial equipment using clean-in-place procedures and a pre-treatment solution prior to the conventional CIP cleaning process. The pre-treatment step improves the degree of softening of the soil, and thus facilitates its removal. The pre-treatment solution can be a strong acidic solution, a strong alkaline solution, or comprise a penetrant. A preferred strong acidic solution is an acid peroxide solution. In some embodiments, the pre-treatment may include no strong alkali or acid ingredient; rather, the penetrant provides acceptable levels of pre-treatment.
Owner:ECOLAB USA INC
Method of deacidizing a gas with a fractional regeneration absorbent solution
The gaseous effluent flowing in through line 1 is contacted in absorption zone ZA with the liquid absorbent solution flowing in through line 9. The gaseous effluent depleted in acid compounds is discharged through line 2. The absorbent solution laden with acid compounds is discharged through line 3. The absorbent solution once laden with acid compounds comprises two phases: a first phase poor in acid compounds and a second phase rich in acid compounds. The two phases are separated in zone ZS. The first phase is recycled through lines 5 and 9 to absorption zone ZA. The second phase is fed through line 4 into regeneration zone ZR. In zone ZR, the acid compounds are separated from the absorbent solution. The acid compounds are discharged through line 7. The regenerated absorbent solution is recycled through lines 6 and 9 to zone ZA.
Owner:INST FR DU PETROLE
Formulations having increased stability during transition from hydrophobic vehicle to hydrophilic medium
InactiveUS20050266087A1Sufficient amountFacilitated releaseBiocideOrganic active ingredientsAntioxidantCompound (substance)
A suspension formulation for therapeutic use includes a non-aqueous, hydrophobic vehicle exhibiting viscous fluid characteristics, a dry particle formulation comprising a biomolecule dispersed in the vehicle, and a surfactant incorporated in at least one of the vehicle and dry particle formulation. A dry particle formulation includes an interferon, a buffer, a surfactant, and one or more stabilizers selected from the group consisting of a carbohydrate, an antioxidant, and an amino acid.
Owner:INTARCIA THERAPEUTICS INC
Method of preparing cannabidiol from plant material
InactiveUS20060167283A1Reduce the ratioOrganic chemistryHydroxy compound active ingredientsCannabidiolChromatography
The invention relates to methods of preparing cannabidiol in substantially pure form starting from plant material. Also described are substantially pure preparations of cannabidiol having a chromatographic purity of 95% or greater.
Owner:FLOCKHART IAN +3
Method of removing a biofilm
The present invention relates to a method of removing a biofilm, which comprises at least the following steps, carried out simultaneously or consecutively: a) a solution comprising an enzyme mixture containing at least one enzyme chosen from the group of proteases, at least one enzyme chosen from the group of esterases and an amylase is prepared; b) a solution comprising a detergent with an alkaline pH is prepared; and c) said solutions are applied, by washing or by circulation, to the surface to be treated. It also relates to a kit intended for removing a biofilm, which comprises the solutions defined above and the compositions comprising the said solutions.
Owner:KARINE MARION +1
Microfluidic device containing lyophilized reagent therein and analyzing method using the same
InactiveUS20090286327A1Bioreactor/fermenter combinationsBiological substance pretreatmentsMicrofluidicsAnalysis method
Provided is a microfluidic device suitable for analyzing a liquid sample. The device includes a first chamber to contain a sample; a second chamber to contain a liquid first reagent; a third chamber containing a lyophilized second reagent; a plurality of channels connecting the first, second, and third chambers.
Owner:SAMSUNG ELECTRONICS CO LTD
Stable liquid enzyme compositions
InactiveUS20050020466A1Improved soilStable maintenanceInorganic/elemental detergent compounding agentsSurface-active detergent compositionsHigh concentrationPotassium
The present invention relates to a liquid enzyme cleaning composition in which the enzyme is stable at alkaline pH and: at high concentration of boric acid salt; in the absence of sodium ion; and / or in the presence of at least about 40 wt-% water. In an embodiment, water is present at concentrations of at least about 60 weight percent. The present enzyme cleaning composition typically yields superior soil (especially protein soil) removal properties. In an embodiment, the composition of the invention stabilizes the enzyme with potassium and / or alkanolamine borate.
Owner:ECOLAB USA INC
Process for the simultaneous production of xylitol and ethanol
InactiveUS20060246563A1Guaranteed economic efficiencySemi-permeable membranesBiofuelsCelluloseChromatographic separation
Owner:DANISCO SWEETENERS
High PUFA oil compositions
ActiveUS20060110521A1Organic chemistryFatty substance preservation using additivesHigh concentrationFatty acids.polyunsaturated
The present invention is directed to oil compositions having a high concentration of poly-unsaturated fatty acids. In addition, the oils of the present invention have advantageous stability characteristics and minimal trans-fatty acids.
Owner:MONSANTO TECH LLC
Lateral flow assay device and method
InactiveUS20060160078A1Improved capillary flowStrong water absorptionBioreactor/fermenter combinationsBiological substance pretreatmentsNucleic acid sequencingNucleic acid sequence
Disclosed is a lateral flow assay device to test for the presence and / or amount of a nucleic acid sequence of interest in a sample, the lateral flow device comprising: (a) a sample receiving zone for contacting the device with a sample to be tested; (b) an extraction zone (8) for extraction of nucleic acid from the sample; (c) a nucleic acid amplification zone (18) in liquid communication with the sample receiving zone; and (d) a detection zone (20) for detecting the products, directly or indirectly, of a nucleic acid amplification reaction performed in the nucleic acid amplification zone, said detection zone (20) being, or being locatable, in liquid communication with the amplification zone (18).
Owner:BRITISH BIOCELL INT
Switchable solvents and methods of use thereof
InactiveUS20080058549A1Low viscosityOrganic compounds purification/separation/stabilisationSolvent extractionAlcoholNon ionic
A solvent that reversibly converts from a nonionic liquid mixture to an ionic liquid upon contact with a selected trigger, e.g., contact with CO2, is described. In preferred embodiments, the ionic solvent is readily converted back to the nonionic liquid mixture. The nonionic liquid mixture includes an amidine or guanidine or both, and water, alcohol, or a combination thereof. Single component amine solvents that reversibly convert between ionic and non-ionic states are also described. Some embodiments require increased pressure to convert; others convert at 1 atmosphere.
Owner:GEORGIA TECH RES CORP +1
Friction Reduction Fluids
InactiveUS20080064614A1Good drag reduction effectImproved viscousPipeline systemsFlushingFriction reductionReducer
The invention provides an oilfield suspending friction reducer treatment composition fluid comprising from about 0.001 weight percent to about 0.5 weight percent of a drag reducing surfactant; at least one drag reducing enhancer selected from the group consisting of polymeric drag reduction enhancers, monomeric drag reduction enhancers, and mixtures thereof.
Owner:SCHLUMBERGER TECH CORP
Carbon dioxide capture systems and methods
A carbon dioxide separation system comprises a first flow path for directing a fluid comprising carbon dioxide therethrough, a second flow path for directing a sweep fluid therethrough, and a separator comprising a material with selective permeability of carbon dioxide for separating the first and the second flow paths and for promoting carbon dioxide transport therebetween. A carbon dioxide separation unit is in fluid communication with the second flow path for separating the transported carbon dioxide from the sweep fluid.
Owner:GENERAL ELECTRIC CO
Pharmaceutically acceptable composition comprising an aqueous solution of paclitaxel and albumin
InactiveUS20050282734A1Prevent restenosisFree of organic solventsBiocideOrganic active ingredientsOrganic solventSerum protein albumin
An optically clear, pharmaceutically acceptable aqueous composition comprising paclitaxel or a derivative thereof, serum albumin and a pharmaceutically acceptable vehicle, wherein the composition comprises no more than 10% organic solvent and has a pH of about 3.0 to about 4.8, is described. The serum albumin can be fatted or defatted, and the composition can optionally be lyophilized or optionally lyophilized and reconstituted. At least 70% of the paclitaxel is bound to serum albumin, the ratio of paclitaxel to albumin is at least about 1:5, and the concentration of paclitaxel is at least about 25 μg / ml. Methods of making and using this composition an also provided.
Owner:KADIMA TENSHUK A +6
Devices and processes for nucleic acid extraction
ActiveUS20090215125A1Bioreactor/fermenter combinationsBiological substance pretreatmentsFlat glassBinding site
Devices, processes, and kits for the extraction of nucleic acids from biological samples are disclosed. The devices comprise a first port, a second port, and a binding chamber intermediate and in fluid communication with the first port and the second port. The binding chamber comprises an unmodified flat glass surface effective for binding a heterogeneous population of nucleic acids. The first port, second port, and binding chamber define a continuous fluid pathway that is essentially free of nucleic acid-specific binding sites.
Owner:BLOOD CELL STORAGE
Ultraporous sol gel monoliths
ActiveUS20060131238A1Shorten the timeEasy to optimizeIon-exchange process apparatusPhysical/chemical process catalystsPorosityHYDROSOL
Ultraporous sol gel monoliths and methods for preparing the same are provided, having superior flow characteristics for chromatography and analytical chemistry applications. The methods for forming an ultra porous sol-gel monolith include (a) forming a solution comprising a porogen, a matrix dissolving catalyst and a sol gel precursor; (b) allowing the solution to form a gel; and (c) drying the gel at an elevated temperature. The ultraporous sol gel monoliths are characterized by a porosity of up to about 97%, a BET surface area of at least about 50 m2 / g and substantially no micropores.
Owner:AGILENT TECH INC
Alkaline post-chemical mechanical planarization cleaning compositions
InactiveUS20050205835A1Organic detergent compounding agentsDetergent mixture composition preparationOrganic baseCarboxylic acid
A post-CMP cleaning composition and method comprising same are disclosed herein. In one aspect, there is provided a composition comprising: water, an organic base, and a plurality of chelating agents comprised of a poly-amino carboxylic acid and a hydroxylcarboxylic acid wherein the pH of the composition ranges from 9.5 to 11.5.
Owner:VERSUM MATERIALS US LLC
High throughput screening of fatty acid composition
InactiveUS20070048872A1Process can be speededEasy to sampleBiological testingFatty-oils/fats productionHigh-Throughput Screening MethodsAdemetionine
A method for the high throughput screening of fatty acid characteristics in seeds is provided. The method comprises feeding seeds individually to a sampling station; removing a sample from the seed in the sampling station; conveying the sample to a compartment in a sample tray; converting extracted oil from the sample in the sample tray to form a mixture of fatty acid methyl esters; and analyzing the mixture of fatty acid methyl esters from the sample to determine the fatty acid profile of the corresponding seed.
Owner:MONSANTO TECH LLC
Composition for wet wipes containing a non-irritating skin health benefit ingredient and the process for making
InactiveUS20060171971A1Easy to handleEasy to storeCosmetic preparationsHair removalParticulatesAdditive ingredient
Owner:THE PROCTER & GAMBLE COMPANY
Adsorbent for separating nitrogen from mixed gas of oxygen and nitrogen
InactiveUS6916358B2Minimal operating costMore productiveNitrogen purification/separationGas treatmentSorbentNitrogen
An adsorbent for separating nitrogen from a mixed gas of oxygen and nitrogen is MSC wherein an oxygen and nitrogen separation ratio α and a ratio (t95 / t50) of a time t50 required for adsorbing 50% of the oxygen equilibrium adsorption amount and a time t95 required for adsorbing 95% of the oxygen equilibrium adsorption amount satisfy the inequality(t95 / t50)<0.4×(α−24)α≧35.The amount of adsorbent used with respect to a predetermined amount of nitrogen generated can be reduced since a method is carried out which uses this adsorbent to produce nitrogen by separating nitrogen from the mixed gas of oxygen and nitrogen by means of a PSA method. By this method, it is possible to reduce the cost of the apparatus and reduce and miniaturize the scale of the apparatus, and the power consumption amount can be reduced.
Owner:NIPPON SANSO CORP
Liquid antimicrobial cleansing compositions which provide residual benefit versus gram negative bacteria
The present invention relates to a rinse-off antimicrobial cleansing composition comprising from about 0.001% to about 5% of an antimicrobial active, from about 1% to about 80% of an anionic surfactant, from about 0.1% to about 12% of a proton donating agent; from about 0.1% to about 30% of a deposition aid; and from about 3% to about 98.8% of water, wherein the composition is adjusted to a pH of from about 3.0 to about 6.0, wherein the rinse-off antimicrobial cleansing composition has a Gram Negative Residual Effectiveness Index of greater than about 0.3, and wherein the rinse-off antimicrobial cleansing composition has a Mildness Index of greater than 0.3. The invention also encompasses methods for cleansing skin and providing residual effectiveness versus Gram negative bacteria using these products.
Owner:THE PROCTER & GAMBLE COMPANY
Method for saccharification of woody biomass
InactiveUS20080026431A1Efficient and inexpensive methodEfficiently converted into energyBiofuelsFermentationSugarHydrolysis
Provided is an inexpensive and efficient saccharification method for woody biomass and a method of producing ethanol from woody biomass. A method for saccharification of woody biomass comprising hydrolysis treatment and an enzymatic treatment, in which a pretreatment process is performed prior to the enzymatic treatment and said pretreatment includes the steps of: hydrolyzing woody biomass, separating the resultant reaction product into a primary sugar solution and a residue, mixing the residue with an aqueous alkaline solution, and mixing with an oxidant capable of generating active oxygen.
Owner:TAISEI CORP
Antibody purification by protein a and ion exchange chromatography
ActiveUS20060194953A1Serum immunoglobulinsImmunoglobulins against animals/humansIon exchangeAntibody Affinity Chromatography
A novel method for selectively removing leaked protein A from antibody purified by means of protein A affinity chromatography is disclosed.
Owner:LONZA BIOLOGICS PLC
Sterilization of Biosensors
InactiveUS20070111196A1Microbiological testing/measurementDiagnostic recording/measuringBinding domainEnzyme
The present invention relates to methods of making a sterilized biosensor, where the biosensor comprises at least one binding reagent, which comprises at least one non-enzyme proteinaceous binding domain. Certain embodiments of the methods described herein comprise partially assembling the components of the biosensor, except for the binding reagent, and separately sterilizing this partial assemblage and the binding reagent. The sterilized binding reagent and the sterilized partial assemblage are then aseptically assembled to produce the sterilized biosensor. Other embodiments of the methods described herein comprise assembling substantially all of the components of the biosensor, including the binding reagent, and sterilizing the assembled biosensor to produce a sterilized biosensor.
Owner:BECTON DICKINSON & CO
Multiphase cosmetic composition
ActiveUS20050249758A1Easy to disassembleGood emulsificationBiocideCosmetic preparationsVegetable oilPolyol
The present invention relates to a multi-phase cosmetic composition for application to the body, which has a liquid and transparent appearance, becomes a homogeneous mixture after being stirred, the phases raps idly separating when at rest. The composition according to the present invention comprises at least one oily phase and at least one aqueous phase, further comprising a polyol, the oily phase comprising a mixture of at least one mineral oil and at least one vegetable oil, and the aqueous phase comprising a water-soluble salt.
Owner:NATURA COSMETICOS SA
Gas separation vessel apparatus
InactiveUS20060236867A1Easy to manage on siteSmall sizeGas treatmentIsotope separationOxygenChromatography
An improved gas separation vessel apparatus is provided. The gas separation vessel apparatus is adapted to separate oxygen and other process gases, and it employs both vertically-, or alternatively, horizontally-positioned vessels. The gas separation vessels disclosed contain removable radial-flow bed cartridge-type adsorbent subassemblies, which may be replaced, substituted, or serviced with minimal system down time.
Owner:AES DEV CO
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