11373results about How to "Facilitated release" patented technology

A surgical stapling apparatus includes a housing, an end effector, fasteners, and one or more surgical buttresses. The end effector is secured to the housing and has first and second jaw assemblies. The first jaw assembly defines slots and the second jaw assembly defines pockets. One or both of the first and second jaw assemblies define recesses. The fasteners are disposed in the slots of the first jaw assembly and are formed by the pockets of the second jaw assembly. The one or more surgical buttresses have a body that includes plugs that are integrally formed with the body for insertion into the recesses to secure the surgical buttress(es) to one or both of the first and second jaw assemblies. The body substantially overlies at least some of the slots of the first jaw assembly and / or at least some of the pockets of the second jaw assembly.

A medical manipulator is provided with a brake release mechanism. The brake release mechanism is provided with a release button which is provided on a tilt wheel, and a lever mechanism which has at least one portion arranged on the inside of the tilt wheel and which is pressed when the release button moves inwards. By the action of the lever mechanism when the release button is operated, braking by a brake mechanism is released.

Clips of a self-closing type are used in annuloplasty procedures. Each clip is generally U-shaped with two end points separated from each other when it is constrained to be in an open configuration, but tends to coil up to assume its naturally closed configuration if the constraint is removed. A plurality of such clips in open configurations penetrate the tissue around the annulus circumferentially and then the constraint keeping them in the open configuration is removed such that they pull the tissue together between their two end points and this tends to reduce the diameter of the annulus. Such clips may be deployed each in the form of a clip assembly, having at least one of its end points connected to a needle through a flexible member and a release mechanism by which the clip can be easily released. The needle is caused to penetrate the tissue at one position and to come out therefrom at another circumferentially separated positions. Alternatively, a clip delivery device may be used with a plurality of such clips loaded to a clip-holder serving to keep them in open configurations. A pusher pushes the loaded clips out of the device one at a time. Self-closing clips can be used efficiently also in ring annuloplasty and valve replacement procedures.

Methods and materials for delivering biologically active molecules to cells in vitro or in vivo are provided. The methods and materials use carbon nanotubes or other hydrophobic particles, tubes and wires, functionalized with a linking group that is covalently bound to the nanotubes, or, alternatively, to the biologically active molecule, such as a protein. The biologically active molecule is preferably released from the nanotube when the complex has been taken up in an endosome.