1464 results about "Solution flow" patented technology

An electrical detector is provided that comprises a nanofluidic channel with an integrated nanoscale charge sensor. The charge sensor can be an unfunctionalized nanowire, nanotube, transistor or capacitor and can be of carbon, silicon, carbon / silicon or other semiconducting material. The nanofluidic channel depth is on the order of the Debye screening length. Methods are also provided for detecting charged molecules or biological or chemical species with the electrical detector. Charged molecules or species in solution are driven through the nanofluidic channel of the electrical detector and contact the charge sensor, thereby producing a detectable signal. Methods are also provided for detecting a local solution potential of interest. A solution flowing through the nanofluidic channel of the electrical detector contacts the charge sensor, thereby producing a detectable local solution potential signal.

A vascular access device and method of using is disclosed. The vascular access device includes a housing defining a cavity and adapted to connect to a catheter. A self-sealing injection port and a subhousing are also provided. The subhousing may be movably connected to the housing so that a position of the other end of the subhousing relative to the housing can be selectively adjusted within a range of positions. A unidirectional fluid valve permits solution flow from the subhousing to the housing. The vascular access device may be utilized in a variety of treatment protocols including medication administration, fluid sampling, and placement of balloon catheters or guide wire-based medical devices.

The gaseous effluent flowing in through line 1 is contacted in absorption zone ZA with the liquid absorbent solution flowing in through line 9. The gaseous effluent depleted in acid compounds is discharged through line 2. The absorbent solution laden with acid compounds is discharged through line 3. The absorbent solution once laden with acid compounds comprises two phases: a first phase poor in acid compounds and a second phase rich in acid compounds. The two phases are separated in zone ZS. The first phase is recycled through lines 5 and 9 to absorption zone ZA. The second phase is fed through line 4 into regeneration zone ZR. In zone ZR, the acid compounds are separated from the absorbent solution. The acid compounds are discharged through line 7. The regenerated absorbent solution is recycled through lines 6 and 9 to zone ZA.

A spiral microchannel particle separator includes an inlet for receiving a solution containing particles, at least two outlets, and a microchannel arranged in a plurality of loops. Particles within a solution flowing through the spiral microchannel experience a lift force FL and a Dean drag force FD. The spiral radius of curvature R and the hydraulic diameter Dh of the spiral microchannel are such that for a flow rate U of the solution, the lift force FL and a Dean drag force FD are approximately equal and act in opposite directions for particles of a first size. The particles of the first size are focused in a single stream located at an equilibrium position near an inner wall of the microchannel. In another embodiment, a straight microchannel particle separator separates particles by modulating shear rates via high aspect ratios that focuses particles of a first size along two first walls.

A system, a method and administration lines are provided for self-priming of a solution delivery system. The administration lines are arranged such that resultant forces acting on the lines create different forces applied on each lumen resulting in solution flowing in one of the lumen undergoing a higher isostatic pressure. The lumens forming the administration line may be formed from concentric tubings or formed from separate tubings extending varied lengths into the solution container. As a result, automatic priming of the administration line and the solution delivery system is provided.

Charged droplet spray is formed from a solution with all or a portion of the charged droplet spray current generated from reduction or oxidation (redox) reactions occurring on surfaces removed from the first or sample solution flow path. In one embodiment of the invention, two solution flow channels are separated by a semipermeable membrane. A first or sample solution flowing through the first solution flow channel exchanges cation or anion charged species through the semipermeable membrane with a second solution or gas flowing through the second flow channel. Charge exchange is driven by the electric field applied at the charged droplet sprayer sample solution outlet. Redox reactions occur at an electrode surface in contact with the second solution. The invention increases the control and range of the Electrospray ionization process during ES / MS operation. Alternative embodiments of the invention provide for conducting redox reactions on conductive surfaces removed from the first or sample solution flow path but not separated by semipermeable membranes.

The invention provides a method and apparatus for preparation of radiochemicals, such as PET molecular imaging probes, wherein the reaction step or steps that couple the radioactive isotope to an organic or inorganic compound to form a positron-emitting molecular imaging probe are performed in a microfluidic environment. The method for synthesizing a radiochemical in a microfluidic environment comprises: i) providing a micro reactor comprising a first inlet port, a second inlet port, an outlet port, and at least one microchannel in fluid communication with the first and second inlet ports and the outlet port; ii) introducing a reactive precursor into the first inlet port of the micro reactor, the reactive precursor adapted for reaction with a radioactive isotope to form a radiochemical; iii) introducing a solution comprising a radioactive isotope into the second inlet port of the micro reactor; iv) contacting the reactive precursor with the isotope-containing solution in the microchannel of the micro reactor; v) reacting the reactive precursor with the isotope-containing solution as the reactive precursor and isotope-containing solution flow through the microchannel of the micro reactor, the reacting step resulting in formation of a radiochemical; and vi) collecting the radiochemical from the outlet port of the micro reactor.

A optical sensor for measuring tranmissive properties of a solution having: a cuvette body with an enclosed flow passage for the solution, wherein the flow passage further includes a solution inlet and a solution outlet and a cuvette between the inlet and outlet; a light source projecting light of a predetermined wavelength through the cuvette and solution flowing through the cuvette and to a light sensor, wherein the cuvette has inner wall surfaces opaque to the light of said predetermined wavelength, and the inner wall is in contact with the solution.

The gaseous effluent flowing in through line 1 is contacted in absorption zone ZA with the liquid absorbent solution flowing in through line 9. The gaseous effluent depleted in acid compounds is discharged through line 2. The absorbent solution laden with acid compounds is discharged through line 3. The absorbent solution once laden with acid compounds comprises two phases: a first phase poor in acid compounds and a second phase rich in acid compounds. The two phases are separated in zone ZS. The first phase is recycled through lines 5 and 9 to absorption zone ZA. The second phase is fed through line 4 into regeneration zone ZR. In zone ZR, the acid compounds are separated from the absorbent solution. The acid compounds are discharged through line 7. The regenerated absorbent solution is recycled through lines 6 and 9 to zone ZA.

The invention discloses a heat pump-driven membrane-type liquid dehumidification and energy storage device which comprises a dehumidification solution storage tank, a solution pump, a dehumidifier, a first heat exchanger, a fan, a regenerator and a heat pump. The heat pump is a closed circulation loop composed of an evaporator, a compressor, a condenser, a refrigerant reservoir and an expansion valve or a capillary tube which are connected in turn; the dehumidification solution storage tank is connected with the dehumidifier through the solution pump; the dehumidifier is connected with the first heat exchanger and the condenser of the heat pump in turn and then is connected with the liquid inlet of the regenerator; the liquid outlet of the regenerator is connected with the first heat exchanger and the evaporator of the heat pump in turn and then is connected with the dehumidification solution storage tank; the air inlets of the dehumidifier and the regenerator are both connected with the fan; and the dehumidifier and the regenerator are both membrane components capable of isolating the dehumidification solution flowing through the membrane components from the air. The membrane has selective permeability, only allows steam to permeate and can effectively prevent the tiny droplets of the dehumidification solution from being carried in the air; and moreover, the device has the advantage of high utilization rate of energy.

A spotting device for manufacturing a DNA microarray and a spotting method using the same are provided. The spotting device for dropping and immobilizing a solution of biomolecules, for example nucleic acids such as probe DNA, mRNA, and peptide nucleic acid (PNA), and proteins on a DNA microarray surface to manufacture a DNA microarray, includes a first microchannel with a tube shape; a supplying unit supplying the solution of biomolecules to the first microchannel; a biomolecule solution droplet forming unit cross-linked to the first microchannel and forming biomolecule solution droplets with a predetermined size by periodically jetting a gas toward the biomolecule solution flowing in the first microchannel; a second microchannel linked to the first microchannel and having a greater diameter than the first microchannel; a cooling unit surrounding at least a part of the second microchannel to freeze the biomolecule solution droplets which pass through the second microchannel; and a spotting unit thawing the frozen biomolecule solution droplets and dropping the thawed biomolecule solution droplets on a surface of the DNA microarray. The spotting device can form spots with uniform shape, minimize an effect of temperature on biomolecules, and easily manipulate biomolecules when manufacturing a DNA microarray.

The invention relates to a preparation method of a vanadium battery electrolyte solution with high purity and high concentration. The vanadium battery electrolyte solution is different from a traditional vanadium electrolyte solution with vanadium pentoxide as raw material; through the method, a qualified vanadium solution produced by a vanadium factory is adopted as raw material, steps of removing impurities, precipitating vanadium, reducing, extracting and removing oil are carried out, after carrying out processes of four-step impurity removal and one-step reduction, the impurities in the electrolyte solution are effectively removed, and the all-vanadium solution flow battery vanadyl sulfate electrolyte solution with high purity and high concentration and with the concentration of 1-4 M is obtained. The method adopts the initial vanadium solution as the raw material, has the advantages of low cost, simple preparing procedures, and mild reaction conditions, allows the obtained electrolyte solution product to have high purity, and is suitable for application in an all-vanadium solution flow battery.

A biosensor system is provided for detecting biological species such as bacteria, proteins, viruses, spores and DNA or RNA. The biosensor system may also be able to distinguish between Gram positive and Gram negative bacteria. In some embodiments, the analyte solution flows past a detector surface to a filter, which traps the analyte. The analyte is then washed back past the detector surface, thus increasing the number of analyte species that become attached to the surface. The detector may include an optical microresonator that is optically coupled via waveguides to a light source and an optical detector. One of the waveguides may be provided with a wavelength selective reflector to increase the amount of probe light coupled into the microresonator or to increase the fraction of the signal light detected by the optical detector.

A optical sensor for measuring tranmissive properties of a solution having: a cuvette body with an enclosed flow passage for the solution, wherein the flow passage further includes a solution inlet and a solution outlet and a cuvette between the inlet and outlet; a light source projecting light of a predetermined wavelength through the cuvette and solution flowing through the cuvette and to a light sensor, wherein the cuvette has inner wall surfaces opaque to the light of said predetermined wavelength, and the inner wall is in contact with the solution.

The invention belongs to the technical field of micro fluid control, particularly disclosing a micro fluid control chip and a preparation method and application thereof. One side of the chip is provided with a plurality of sample introduction holes, each sample introduction hole is communicated with a sample introduction runner; after meeting, each sample introduction runner is communicated with a main runner; the main runner is provided with a narrow runner; a micro-sphere of which the size is 0.5-1.5 mm is filled in front of the inlet of the narrow runner; the outlet of the main runner is communicated to a waste liquid tank arranged at the other side of the chip. The preparation method mainly comprises: firstly preparing a PDMS substrate; then, preparing a PDMS cover plate with an upper groove; sticking the substrate onto the cover plate to obtain a semi-finished product of the chip; carrying out modified treatment on each runner in the semi-finished product of the chip; finally, putting the micro-sphere in, controlling the charge quantity, and finishing production. The micro fluid control chip of the invention has high solution mixing efficiency, stable solution flow rate, small volume, convenient carrying and relatively simple manufacturing; when being used for detecting the density of triphosadenine, the micro fluid control chip has the advantages of high sensitivity, favourable detection effect and the like and can not be affected by environment humidity.

The invention provides a method and apparatus for preparation of radiochemicals wherein the reaction that couples the radioactive isotope to the reactive precursor to form a positron-emitting molecular imaging probe is performed in a microfluidic environment. The method comprises: providing a micro reactor; introducing a liquid reactive precursor dissolved in a polar aprotic solvent into an inlet port of the micro reactor, the reactive precursor adapted for reaction with a radioactive isotope to form a radiochemical; introducing a solution comprising a radioactive isotope dissolved in a polar aprotic solvent into another inlet port of the micro reactor; contacting the reactive precursor with the isotope-containing solution in a microchannel of the micro reactor; reacting the reactive precursor with the isotope-containing solution as the reactive precursor and isotope-containing solution flow through the microchannel of the micro reactor, wherein the reacting step is conducted at a temperature above the boiling point of the polar aprotic solvent at 1 atm and at a pressure sufficient to maintain the polar aprotic solvent in liquid form; and collecting the resulting radiochemical from the micro reactor.

A biosensor includes a supporting layer, a reference electrode layer, a working electrode layer, a counter electrode layer, and a temperature detection device, which are formed on a front surface of the supporting layer, an enzyme film that coats a surface of the working electrode layer, and a heater member formed on a back surface of the supporting layer. A biosensor cell includes a sample chamber to which a sample solution flows in and out, and the above-described biosensor.

An alkaline solution ref lux path which refluxes an alkaline solution being discharged from an alkaline solution discharge port 101 of an absorber 100 to an alkaline solution introduction port 102 to absorb carbon dioxide and the like, and an alkaline solution reflux path which refluxes a regenerated alkaline solution being discharged from a regenerated alkaline solution discharge port 111 of a regenerator 110 to an alkaline solution jet port 112 and discharges the carbon dioxide to regenerate an alkaline solution are disposed separately and independently. Thus, the flow rates and the like of the alkaline solutions flowing through the individual alkaline solution reflux paths can be set individually.

The present invention provides microfluidic devices and methods for using the same. In particular, microfluidic devices of the present invention are useful in conducting a variety of assays and high throughput screening. Microfluidic devices of the present invention include elastomeric components and solid substrate component for attaching ligand(s) on its surface. The elastomeric layer comprises (a) a plurality of first flow channels; (b) a plurality of second flow channels each intersecting and crossing each of said first flow channels thereby providing a plurality of intersecting areas formed at intersections between said first flow channels and said second flow channels, wherein said plurality of first flow channels and said plurality of second flow channels are adapted to allow the flow of a solution therethrough, and wherein said solid substrate surface is in fluid communication with at least said intersecting areas of said plurality of first flow channels and said plurality of second flow channels, and wherein said plurality of first flow channels and / or said plurality of second flow channels are capable of forming a plurality of looped flow channels; (c) a plurality of control channels; (d) a plurality of first control valves each operatively disposed with respect to each of said first flow channel to regulate flow of the solution through said first flow channels, wherein each of said first control valves comprises a first control channel and an elastomeric segment that is deflectable into or retractable from said first flow channel upon which said first control valve operates in response to an actuation force applied to said first control channel, the elastomeric segment when positioned in said first flow channel restricting solution flow therethrough; (e) a plurality of second control valves each operatively disposed with respect to each of said second flow channel to regulate flow of the solution through said second flow channels, wherein each of said second control valves comprises a second control channel and an elastomeric segment that is deflectable into or retractable from said second flow channel upon which said second control valve operates in response to an actuation force applied to said second control channel, the elastomeric segment when positioned in said second flow channel restricting solution flow therethrough; (f) a plurality of loop forming control valves each operatively disposed with respect to each of said first and / or said second flow channels to form said plurality of looped flow channels, wherein each of said loop forming control valves comprises a loop forming control channel and an elastomeric segment that is deflectable into or retractable from said first and / or said second flow channels upon which said loop forming control valve operates in response to an actuation force applied to said loop forming control channel, the elastomeric segment when positioned in said first and / or said second flow channels restricting solution flow therethrough thereby forming said looped flow channel; and (g) a plurality of recirculating pumps, and wherein each recirculating pump is operatively disposed with respect to one of said looped flow channels such that circulation of solution through each of said looped flow channels can be regulated by one of said recirculating pumps.

The invention discloses an anaerobic fermentation-incineration combined treatment method for organic wastes. The anaerobic fermentation-incineration combined treatment method is characterized by comprising the following steps of: firstly, crushing the organic wastes, feeding the crushed organic wastes into a slurry mixing pool to be mixed with water or a methane solution to form a fermentation raw material, and feeding the fermentation raw material into an anaerobic fermentation tank for anaerobic fermentation treatment; secondly, performing solid-liquid separation treatment on residual slurry to form the methane solution and dehydrated methane slag; thirdly, making partial methane solution flow back to the slurry mixing pool, discharging surplus methane solution outwards to a sewage treatment facility; fourthly, feeding the dehydrated methane slag into a methane slag drying machine by taking methane generated by the anaerobic fermentation tank as fuel for heating, wherein the moisture content of the dried methane slag is made lower than 40%; fifthly, incinerating the dried methane slag subjected to drying treatment by using the methane collected from the anaerobic fermentation tank as auxiliary fuel for methane slag combustion; and sixthly, producing steam or hot water by a waste heat boiler by using high-temperature flue gas discharged from a methane slag incineration furnace, and supplying the steam or the hot water to the fermentation tank to serve as a hot source for heating or heat insulating. According to the invention, the anaerobic fermentation and the incineration treatment are organically combined, the advantages of the anaerobic fermentation and the incineration treatment are fully exerted, and the reduction, harmlessness and the recycling of rubbish are facilitated.

A method for deionization of a solution, the method comprising functionalizing plural apertures of a graphene sheet to repel first ions in the solution from transiting through the functionalized plural apertures. The non-transiting first ions influence second ions in the solution to not transit through the functionalized plural apertures. The graphene sheet is positioned between a solution flow path input and a solution flow path output. Solution enters the solution flow path input and through the functionalized plural apertures of the graphene sheet, resulting in a deionized solution on the solution flow path output side of the graphene sheet and a second solution containing the first ions and second ions on the solution flow path input side of the graphene sheet.

The invention discloses an array pattern spray printing device based on electrofluid power spray printing. The array pattern spray printing device comprises a metal needle head, a printing layer, a metal substrate, a motion platform and a high-pressure generator, wherein the metal needle head is arranged above the printing layer; the printing layer is arranged on the metal substrate; the metal needle head and the metal substrate are connected to the positive end and the negative end of the high-pressure generator, so that an electric field is formed between the metal needle head and the metal substrate; the metal substrate can be driven to do plane motion by the motion platform so as to drive the printing layer to do motion; and a spray printing solution flows out the metal needle head and forms jet flow to be sprayed to the printing layer which does motion under the action of the electric field, so that the required spray printing patterns can be formed on the printing layer. The invention also discloses a method for preparing the patterns by utilizing the device. According to the device and the method, the high-accuracy array patterns can be manufactured simply and quickly under the engineering environment on the basis of stretching-assisted high-accuracy positioning, so that the limit of the conventional static spray printing technology in aspects of jet flow positioning and the spray printing of the specific patterns is broken through.

A flow cytometer includes a sheath flow cell for forming a sample solution flow by surrounding sample solution containing particles with sheath liquid, a light source for radiating light to the sample solution flow, a detecting part for detecting optical information from particles contained in the sample solution flow and converting it to electric signals, and a signal processing part for extracting fluctuation signals from the electric signals which the detecting part outputs.

A system combines reverse electrodialysis and electrolysis to produce hydrogen gas from the controlled mixing of fresh and salt water. A battery stack is formed of alternating membranes of selectively cation-permeable and anion-permeable membranes. Alternating solutions of fresh and salt water flow between the alternating membrane types, causing cations to flow in one direction and anions in the opposite direction, generating a current and cumulative voltage through the stack—this is reverse electrodialysis. The ends of the stack are terminated in electrodes which are shorted together. A recirculating reagent solution flows back and forth between the cells adjacent to the end electrodes, promoting a hydrogen-producing electrolysis and avoiding generation of unwanted chemicals, for example, chlorine. Alterations in the reagent can cause production of antimicrobial compounds for cleansing the membranes. Periodic polarity reversals reduce membrane scale buildup and enhance efficiency.

The invention discloses an MHC (mechanical-hydrological-chemical) coupled seepage experimental device for testing a toroidal fissured rock sample. The device is provided with a pressure stabilizing mechanism located above the experimental device and used for providing experimental pressure, a loading head located below the pressure stabilizing mechanism and used for transferring the pressure, a confining pressure chamber located below the loading head and providing liquid confining pressure and an axial pressure experimental environment for the sample, and a force transmission column located below the confining pressure chamber, wherein the confining pressure chamber is provided with a vertical annular confining pressure chamber side wall; an upper sealing cover and a lower sealing cover are arranged above and below the confining pressure chamber side wall respectively and provided with through holes respectively; the two through holes are coaxial; at least one solution flowing hole is formed in the confining pressure chamber side wall; and the force transmission column is internally provided with a pipeline I. Each sample is arranged in a corrosive solution with certain pressure, the pressure of the solution provides the confining pressure and an inflow water head, and a loading device and a gas storage tank pressure stabilizing device provide long-duration loads for a creeping test at the two ends of the sample.

The invention provides a multi-functional-region cell three-dimensional co-culture method based on a micro-fluidic chip. The chip is composed of a central main channel which is relatively low and side channels which are relatively high and are arranged on two sides, wherein the main channel and the side channels are connected by virtue of trumpet-shaped grid structures. Specifically, the method comprises the following steps: (1) adding collagen solutions different in composition to the sample inlet of the main channel of the chip and applying negative pressure to the outlet of the main channel, wherein the three collagen solutions flow into the main channel and functional regions, which keep distinct boundaries, are formed on the basis of a lamina flow principle; and (2) sterilizing the chip for a whole night through ultraviolet radiation, and directly blending cells to the collagen solutions which are injected into the main channel, so that cell inoculation can be achieved. By virtue of the micro-fluidic chip designed by the invention, a cell three-dimensional culture system, which has a plurality of independent functional regions, can be constructed in one step; and the method has an important application potential in the construction of in vitro complex cell micro-environments.