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327 results about "Biological species" patented technology
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The biological species concept gives an explanation of how species form (speciation). A biological species is a group of individuals that can breed together (panmixia). However, they cannot breed with other groups. In other words, the group is reproductively isolated from other groups.
NMR device for detection of analytes
ActiveUS20070116602A1Add waterHigh sensitivityMaterial analysis by electric/magnetic meansAnalysis using nuclear magnetic resonanceTarget analysisPoint of care
This invention relates generally to detection devices having one or more small wells each surrounded by, or in close proximity to, an NMR micro coil, each well containing a liquid sample with magnetic nanoparticles that self-assemble or disperse in the presence of a target analyte, thereby altering the measured NMR properties of the liquid sample. The device may be used, for example, as a portable unit for point of care diagnosis and / or field use, or the device may be implanted for continuous or intermittent monitoring of one or more biological species of interest in a patient.
Owner:T2 BIOSYST
Active immunization using a siderophore receptor protein
InactiveUS6027736AEasy to produceInhibition capacityAntibacterial agentsBacterial antigen ingredientsADAMTS ProteinsMicrobiology
The invention provides a vaccine for immunizing poultry and other animals against infection by a gram-negative bacteria, and a method of immunizing an animal using the vaccine. The vaccine may contain purified siderophore receptor proteins derived from a single strain or species of gram-negative bacteria or other organism, which are cross-reactive with siderophores produced by two or more strains, species or genera of gram-negative bacteria. The invention further provides a process for isolating and purifying the siderophore receptor proteins, and for preparing a vaccine containing the proteins. Also provided is a method for diagnosing gram-negative sepsis.
Owner:EPITOPIX LLC
Quantum wire sensor and methods of forming and using same
ActiveUS20090014757A1Improve device sensitivitySensitive highNanotechSemiconductor/solid-state device testing/measurementField-effect transistorElectric conductance
A solid-state field-effect transistor device for detecting chemical and biological species and for detecting changes in radiation is disclosed. The device includes a quantum wire channel section to improve device sensitivity. The device is operated in a fully depleted mode such that a sensed biological, chemical or radiation change causes an exponential change in channel conductance of the transistor.
Owner:THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIV OF ARIZONA
NMR device for detection of analytes
ActiveUS20090134869A1Add waterHigh sensitivityAnalysis using nuclear magnetic resonanceElectric/magnetic detectionTarget analysisPoint of care
This invention relates generally to detection devices having one or more small wells each surrounded by, or in close proximity to, an NMR micro coil, each well containing a liquid sample with magnetic nanoparticles that self-assemble or disperse in the presence of a target analyte, thereby altering the measured NMR properties of the liquid sample. The device may be used, for example, as a portable unit for point of care diagnosis and / or field use, or the device may be implanted for continuous or intermittent monitoring of one or more biological species of interest in a patient.
Owner:T2 BIOSYST
Active immunization using a siderophore receptor protein
InactiveUS6432412B1Easy to produceInhibition capacityAntibacterial agentsBiocideADAMTS ProteinsMicrobiology
Owner:EPITOPIX LLC
Dynamically controllable biological/chemical detectors having nanostructured surfaces
ActiveUS7048889B2Bioreactor/fermenter combinationsBiological substance pretreatmentsChemical compoundBiological species
Owner:LUCENT TECH INC
Systems and methods for biosensing and microresonator sensors for same
InactiveUS20060062508A1Fast resultsLess expensiveSamplingMicrobiological testing/measurementSignal lightWaveguide
A biosensor system is provided for detecting biological species such as bacteria, proteins, viruses, spores and DNA or RNA. The biosensor system may also be able to distinguish between Gram positive and Gram negative bacteria. In some embodiments, the analyte solution flows past a detector surface to a filter, which traps the analyte. The analyte is then washed back past the detector surface, thus increasing the number of analyte species that become attached to the surface. The detector may include an optical microresonator that is optically coupled via waveguides to a light source and an optical detector. One of the waveguides may be provided with a wavelength selective reflector to increase the amount of probe light coupled into the microresonator or to increase the fraction of the signal light detected by the optical detector.
Owner:3M INNOVATIVE PROPERTIES CO
Sensor devices containing co-polymer substrates for analysis of chemical and biological species in water and air
InactiveUS20050133697A1Analysing fluids using sonic/ultrasonic/infrasonic wavesBeam/ray focussing/reflecting arrangementsOrganic solventPolymer substrate
Sensor devices are disclosed possessing substrates having enhanced resistance to solvents. The sensor device (10) has a sensor region (12) deposited on a substrate (14). In optional embodiments, a protecting layer (16) is applied over the sensor region. The substrates include polycarbonates combined with solvent resistance-imparting monomers that result in a copolycarbonate substrate immune to attack by organic solvents commonly used in sensor deposition and improve the quality of the deposited sensor regions.
Owner:GENERAL ELECTRIC CO
Dynamically controllable biological/chemical detectors having nanostructured surfaces
ActiveUS20060040375A1Reduce surface tensionBioreactor/fermenter combinationsBiological substance pretreatmentsChemical compoundNanostructure
A biological / chemical detector is disclosed that is capable of manipulating liquids, such as reagent droplets, without relying on microchannels. In a first embodiment, fluid flow is passed through the detector, thus causing particles wholly or partially containing an illustrative chemical compound or biological species to be collected on the tips of nanostructures in the detector. A droplet of liquid is moved across the tips of the nanostructures, thus absorbing the particles into the liquid. The droplet is caused to penetrate the nanostructures in a desired location, thus causing the chemical compound or biological species in said liquid droplet to come into contact with, for example, a reagent. In another embodiment, a fluid flow is passed through the nanostructured surfaces of the detector such that the chemical compound and / or biological species are deposited between the nanoposts of a desired pixel. A droplet of liquid is moved across the surface to that desired pixel and is caused to penetrate the nanostructures of the pixel, thus contacting a reagent.
Owner:LUCENT TECH INC
Polymer coatings containing phytochemical agents and methods for making and using same
InactiveUS20080175812A1Reduce and destroy foulingGrowth inhibitionBiocideAntifouling/underwater paintsPhytochemicalControl release
This invention relates to compositions comprising a polymer base incorporating antifouling compositions suitable for use in aquaculture, marine and architectural systems as paints, structures or coatings. In particular, the present invention relates to a polymer based coating incorporating a biocidal antifouling composition suitable for use with aquaculture equipment. The present invention provides polyethylene compositions and latex compounds which may comprise at least one environmentally benign phytochemicals suitable for use in preventing the colonization of a treated surface by a variety of biological species. The compositions of the invention may further comprise control release agents such as, for example, micro-encapsulation of the phytochemicals to maintain sustained and prolonged release of the biocidal agents at the treated surface.
Owner:MAGELLAN
Chemically-functionalized microcantilevers for detection of chemical, biological and explosive material
InactiveUS20060191320A1Simple and reliable and inexpensive detectorAnalysing fluids using sonic/ultrasonic/infrasonic wavesMaterial nanotechnologyAnalyteCompound (substance)
A chemically functionalized cantilever system has a cantilever coated on one side thereof with a reagent or biological species which binds to an analyte. The system is of particular value when the analyte is a toxic chemical biological warfare agent or an explosive.
Owner:UT BATTELLE LLC +1
Integrated up-flow reactor and advanced treatment method of fermentation industrial effluent
InactiveCN101698555AImprove biodegradabilityPromote degradationTreatment with aerobic and anaerobic processesMultistage water/sewage treatmentRetention timeTreatment field
The invention discloses an integrated up-flow reactor and an advanced treatment method of fermentation industrial effluent, belonging to effluent treatment field. The upper part of the reactor is an aerobic fluidized bed system, the lower part is an anaerobic filter system, the intermediate transition zone is designed to be a connecting part which has a tri-phase separation function and organically combines the upper part and the lower part together. In the reactor, the concentration of biological solid is high and the retention time of biological solid is long, therefore the reactor is suitable for treating secondary biochemical treatment effluent of fermentation industrial effluent which has high salinity and is difficult to be biodegraded; sludge output of each system is low, and the residual sludge generated in the aerobic zone enters to the transition zone and the anaerobic zone to be further treated, the overall sludge output of the reactor is low, and simultaneously, the reactor contains rich biological species which act on organics difficult to be degraded jointly and promote the degradation thereof. The integrated reactor has low energy consumption, less land occupation, convenient operation, load impact resistance and high treatment efficiency, thereby being applicable to the advanced treatment of fermentation industrial effluent.
Owner:NANJING UNIV
Paints, coatings and polymers containing phytochemical agents and methods for making and using same
The present invention provides safe paint and coating compositions comprising at least one environmentally acceptable phytochemical such as, but not limited to capsicum, grapefruit seed extract and menthol suitable for use in preventing the colonization of a treated surface by a variety of biological species. One aspect of the invention is anti-fouling marine paints (coatings). Another aspect of the invention of the present invention provides paint and coating compositions comprising phytochemicals for use as an architectural paint. The compositions of the invention can further comprise control release agents such as, for example, antioxidants, oxidizers or photosensitive compounds to promote sustained release of the anti-colonization agents at the treated surface and to assist in the abrasion of the paint surface to mechanically dislodge the attaching organisms.
Owner:SEABROOK SAMUEL G JR
3D array integrated cells for the sampling and detection of air bound chemical and biological species
InactiveUS6889567B2Easy to mass produceEasy to detectWeather/light/corrosion resistanceWithdrawing sample devicesElectrical resistance and conductanceAnalyte
An integrated mesopump-sensor suitable for disposition in two- and three-dimensional arrays having small dimensions is disclosed. One mesopump is formed of an electrostatically attractable flexible diaphragm disposed through cavities or pumping chambers formed between two opposing electrostatically chargeable material layers. Fluid is pumped through the chambers by sequentially moving the diaphragm toward the first chargeable layer, then towards the second chargeable layer, which can pull and push the fluid through a series of chambers, and past the sensor. One group of sensors utilizes multiple and varied chemoresistive sensors which can vary in resistance differently in response to the presence of various analytes. Another group of sensors utilizes chemo-fluorescent sensors that fluoresce in the presence of particular analytes. Some mesopump-sensor systems can be manufactured using MEMS technology and can be coupled to controllers for sequencing the pumps and analyzing sensor outputs using methods including Principle Component Analysis.
Owner:HONEYWELL INT INC
Magnetic Nanoparticles and Uses Thereof
InactiveUS20130089614A1Increase profitGood flexibilityPowder deliveryMaterial nanotechnologyMagnetite NanoparticlesSilica gel
Magnetic nanoparticles are provided that have a superparamagnetic core and a nanoporous silica shell surrounding the core. The shell is functionalized with amine or S-nitrosothiol groups both inside and outside the nanopores. A process to provide such nanoparticles involves hydrolyzing tetraethoxysilane (TEOS) in a microemulsion of a superparamagnetic nanoparticle to form a superparamagnetic nanoparticle encapsulated by an incompletely hydrolyzed nanoporous silica shell, and hydrolyzing an amine-containing compound or a thiol-containing compound in situ in the presence of the incompletely hydrolyzed nanoporous silica shell before hydrolysis and densification of the silica shell is complete to functionalize the nanoporous silica shell with amine or thiol groups both inside and outside the nanopores and to maintain nanoporosity of the shell. Such magnetic nanoparticles are useful as carriers for chemical or biological species, particularly for magnetic resonance imaging, optical imaging, targeted drug delivery, cell delivery and magnetic separation applications.
Owner:ZHANG XUEFENG +1
Emissive species for clinical imaging
InactiveUS7521232B2Relaxes constraintMinimize interactionMicrobiological testing/measurementTissue cultureOligomerNormal cell
The present invention relates to materials and methods useful in the study of cells and species associated with cells. Materials of the present invention may include emissive, photostable organic molecules (e.g., conjugated polymers, conjugated oligomers) that are appropriately functionalized to interact with a cell with essentially no disruption in normal cell functioning. The present invention may be useful in, for example, cell imaging, cell tracking, in vivo monitoring of cellular events, drug delivery, and determination of biological species. In one embodiment, a conjugated polymer or oligomer may be internalized into a cell and may exhibit a strong and stable emissive signal, allowing the cell to be monitored under extensive microscopic conditions for extended periods of time.
Owner:FLIR DETECTION
Antigen-binding molecule inducing immune response to target antigen
ActiveUS20140255398A1Effective treatmentImmunoglobulins against cell receptors/antigens/surface-determinantsAntibody ingredientsImmune response geneCancer cell
The present inventors have discovered that in living organisms that have received an antigen-binding molecule containing an antigen-binding domain whose binding activity to an antigen changes depending on ion concentration conditions and containing an FcRn-binding domain having FcRn-binding activity in a neutral pH range, immune responses to the antigen are induced. Furthermore, the present inventors have discovered that in living organisms that have received an antigen-binding molecule containing an antigen-binding domain whose binding activity to an antigen changes depending on ion concentration conditions and containing an FcRn-binding domain having FcRn-binding activity in a neutral pH range, immune responses to the antigen are induced, and also the antigen-binding molecule has cytotoxicity or antiproliferative action against cancer cells, foreign biological species, or such that express the antigen to which the antigen-binding molecule binds.
Owner:CHUGAI PHARMA CO LTD
Information processing apparatus, information processing method, storage medium and program
InactiveUS20050164217A1Determine biological species easily, inexpensivelyShort timeMicrobiological testing/measurementBiological testingInformation processingHybridization reaction
Biological species are determined easily, inexpensively, in a short time, and accurately even if a plurality biological species having base sequences similar to one another exist in a specimen. For achieving such an object, the information processing apparatus according to the present invention is an information processing apparatus processing information about the signal intensity of each probe obtained as a result of making a predetermined specimen undergo a hybridization reaction using a DNA micro-array in which probes being nucleic acid complementary to some of nucleotide sequences of biological species, the information processing apparatus comprising unit configured to retain a known sample, unit configured to acquire an unknown sample obtained as a result of making the predetermined specimen undergo the hybridization reaction, unit configured extract a vector related to a vector related to a predetermined biological species, of the known sample and unknown sample, and determining unit configured to compare the extracted vector of the known sample with the vector of the unknown sample to determine whether or not the predetermined biological species is contained in the predetermined specimen.
Owner:CANON KK
Emissive species for clinical imaging
InactiveUS20070281289A1Minimize interactionRelaxes constraintMicrobiological testing/measurementTissue cultureMicroscopic scaleBiological species
The present invention relates to materials and methods useful in the study of cells and species associated with cells. Materials of the present invention may include emissive, photostable organic molecules (e.g., conjugated polymers, conjugated oligomers) that are appropriately functionalized to interact with a cell with essentially no disruption in normal cell functioning. The present invention may be useful in, for example, cell imaging, cell tracking, in vivo monitoring of cellular events, drug delivery, and determination of biological species. In one embodiment, a conjugated polymer or oligomer may be internalized into a cell and may exhibit a strong and stable emissive signal, allowing the cell to be monitored under extensive microscopic conditions for extended periods of time.
Owner:FLIR DETECTION
NANO structured field effect sensor and methods of forming and using same
ActiveUS20120055236A1Sensitive highHigh sensitivityNanotechMaterial analysis by electric/magnetic meansElectric conductanceField-effect transistor
A solid-state field-effect transistor sensor for detecting chemical and biological species and for detecting changes in radiation is disclosed. The device includes a porous or structured channel section to improve device sensitivity. The device is operated in a fully depleted mode such that a sensed biological, chemical or radiation change causes an exponential change in channel conductance.
Owner:ARIZONA STATE UNIVERSITY
Surfaces that resist the adsorption of biological species
The present invention provides articles resistant to the adsorption of proteins, cells and bacteria. The articles can either have a chemical chain bonded thereon where the chemical chain can comprise a terminal group free of a hydrogen bond donor or where a hydrogen bond donor is sufficiently buried such that an exposed surface of the article including the chemical chain is free of a hydrogen bond donor. The chemical chain, or plurality of chemical chains, can comprise a monolayer such as a self-assembled monolayer (SAM) which can be homogeneous (one type of SAM) or mixed, i.e. or more different types of SAMs. Other more specific examples of chemical chains are provided. The plurality of chemical chains can comprise a polymer such as a polyamine. In many aspects, the plurality of chemical chains is sufficiently free of cross-linking or branching. The present invention also provides an article capable of specific binding of a desired biomolecule while preventing non-specific binding of biomolecules.
Owner:PRESIDENT & FELLOWS OF HARVARD COLLEGE
Simultaneous sample manipulation and sensing using surface acoustic waves
ActiveUS7878063B1Vibration measurement in solidsAnalysing fluids using sonic/ultrasonic/infrasonic wavesElectricityWhite blood cell
The present invention provides a hexagonal, delay line surface acoustic wave device fabricated on a a piezoelectric substrate, such as lithium tantalate, coated with an insulating waveguide on to which a sensing film, such as an anti-human Interleukin-6 biosensor film, is physically absorbed. The acoustic waves that propagate along the delay lines of the SAW device provide for detection of biological species along one delay line and simultaneously provide for removal of non-specifically bound protein along the remaining delay lines.
Owner:UNIV OF SOUTH FLORIDA +1
Processes and systems for predicting biological species invasions
InactiveUS20030023416A1Difficult to predictEpidemiological alert systemsAnalogue computers for chemical processesEnvironment of AlbaniaBiological species
Methods and systems are disclosed for predicting species invasions. Native species occurrence information and native environmental information are received. At least one ecological niche model is formulated based on the native species occurrence information and the native environmental information. Target environmental information corresponding to an alternative geography is received. The ecological niche model is projected onto the alternative geography to predict characteristics of an invasion of the species.
Owner:KANSAS UNIV OF THE
Chemically-functionalized microcantilevers for detection of chemical, biological and explosive material
InactiveUS7207206B2Material nanotechnologyAnalysing fluids using sonic/ultrasonic/infrasonic wavesAnalyteCompound (substance)
A chemically functionalized cantilever system has a cantilever coated on one side thereof with a reagent or biological species which binds to an analyte. The system is of particular value when the analyte is a toxic chemical biological warfare agent or an explosive.
Owner:UT BATTELLE LLC +1
Systems and methods for biosensing and microresonator sensors for same
InactiveUS7257279B2Less expensiveFast resultsSamplingMicrobiological testing/measurementSignal lightBiological species
A biosensor system is provided for detecting biological species such as bacteria, proteins, viruses, spores and DNA or RNA. The biosensor system may also be able to distinguish between Gram positive and Gram negative bacteria. In some embodiments, the analyte solution flows past a detector surface to a filter, which traps the analyte. The analyte is then washed back past the detector surface, thus increasing the number of analyte species that become attached to the surface. The detector may include an optical microresonator that is optically coupled via waveguides to a light source and an optical detector. One of the waveguides may be provided with a wavelength selective reflector to increase the amount of probe light coupled into the microresonator or to increase the fraction of the signal light detected by the optical detector.
Owner:3M INNOVATIVE PROPERTIES CO
Active immunization using a siderophore receptor protein
InactiveUS20090123500A1Easy to produceInhibition capacityAntibacterial agentsBacterial antigen ingredientsADAMTS ProteinsActive immunization
Owner:EPITOPIX LLC
Active immunization using a siderophore receptor protein
InactiveUS20080293080A1Easy to produceBlock iron binding capacityAntibacterial agentsImmunological disordersActive immunizationBiological species
The invention provides a vaccine for immunizing poultry and other animals against infection by a gram-negative bacteria, and a method of immunizing an animal using the vaccine. The vaccine may contain purified siderophore receptor proteins derived from a single strain or species of gram-negative bacteria or other organism, which are cross-reactive with siderophores produced by two or more strains, species or genera of gram-negative bacteria. The invention further provides a process for isolating and purifying the siderophore receptor proteins, and for preparing a vaccine containing the proteins. Also provided is a method for diagnosing gram-negative sepsis.
Owner:EPITOPIX LLC
Spatially patterned substrates for chemical and biological sensing
InactiveUS20070188749A1Improve overall senseEnhance spectroscopic signal isolationRadiation pyrometrySpectrum investigationHigh fluxImage resolution
A system and method are provided for imaging a test substrate having a test surface that is configured to enable spectroscopic detection of one or more chemical or biological species, wherein the test surface includes a testing site disposed thereon according to a predetermined spatial pattern. The test substrate is provided in an image plane or a Fourier Transform plane of a sensor. The invention provides high throughput and high spectral resolution.
Owner:ASB INT SERVICES LTD
Analytical device
InactiveUS7186356B2Decrease in electrical conductanceDecrease quantum tunnelling conductanceConductive materialResistors adjusted by auxillary driving meansBiological speciesFiller metal
A sensor for chemical species or biological species or radiation presenting to test fluid a polymer composition comprises polymer and conductive filler metal, alloy or reduced metal oxide and having a first level of electrical conductance when quiescent and being convertible to a second level of conductance by change of stress applied by stretching or compression or electric field, in which the polymer composition is characterized by at least one of the features in the form of particles at least 90% w / w held on a 100 mesh sieve; and / or comprising a permeable body extending across a channel of fluid flow; and / or affording in-and-out diffusion of test fluid and / or mechanically coupled to a workpiece of polymer swellable by a constituent of test fluid.
Owner:PERATECH HOLDCO
Luminogens for biological applications
A compound comprises a donor and an acceptor, wherein at least one donor ( "D" ) and at least one acceptor ( "A" ) may be arranged in an order of D-A; D-A-D; A-D-A; D-D-A-D-D; A-A-D-A-A; D-A-D-A-D; and A-D-A-D-A. The compound may be selected from the group consisting of: MTPE-TP, MTPE-TT, TPE-TPA-TT, PTZ-BT-TPA, NPB-TQ, TPE-TQ-A, MTPE-BTSe, DCDPP-2TPA, DCDPP-2TPA4M, DCDP-2TPA, DCDP-2TPA4M, TTS, ROpen-DTE-TPECM, and RClosed-DTE-TPECM. The compound may be used as a probe and may be functionalized with special targeted groups to image biological species. As non-limiting examples, the compound maybe used in cellular cytoplasms or tissue imaging, blood vessel imaging, in vivo fluorescence imaging, brain vascular imaging, sentinel lymph node mapping, and tumor imaging, and the compound may be used as a photoacoustic agent.
Owner:THE HONG KONG UNIV OF SCI & TECH
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