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413 results about "Confocal" patented technology
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In geometry, confocal means having the same foci. For an optical cavity consisting of two mirrors, confocal means that they share their foci. If they are identical mirrors, their radius of curvature, Rₘᵢᵣᵣₒᵣ, equals L, where L is the distance between the mirrors. In conic sections, it is said of two ellipses, two hyperbolas, or an ellipse and a hyperbola which share both foci with each other. If an ellipse and a hyperbola are confocal, they are perpendicular to each other. In optics, it means that one focus or image point of one lens is the same as one focus of the next lens.
Apparatus and method for measuring biologic parameters
ActiveUS20090105605A1Prevent dehydrationAvoid overhydrationThermometer detailsTelevision system detailsInfraredVideo transmission
Support structures for positioning sensors on a physiologic tunnel for measuring physical, chemical and biological parameters of the body and to produce an action according to the measured value of the parameters. The support structure includes a sensor fitted on the support structures using a special geometry for acquiring continuous and undisturbed data on the physiology of the body. Signals are transmitted to a remote station by wireless transmission such as by electromagnetic waves, radio waves, infrared, sound and the like or by being reported locally by audio or visual transmission. The physical and chemical parameters include brain function, metabolic function, hydrodynamic function, hydration status, levels of chemical compounds in the blood, and the like. The support structure includes patches, clips, eyeglasses, head mounted gear and the like, containing passive or active sensors positioned at the end of the tunnel with sensing systems positioned on and accessing a physiologic tunnel.
Owner:BRAIN TUNNELGENIX TECH CORP
Noninvasive measurement of chemical substances
InactiveUS7041063B2High densityEarly diagnosisOrganic active ingredientsHeart defibrillatorsConjunctivaInfrared
Utilization of a contact device placed on the eye in order to detect physical and chemical parameters of the body as well as the non-invasive delivery of compounds according to these physical and chemical parameters, with signals being transmitted continuously as electromagnetic waves, radio waves, infrared and the like. One of the parameters to be detected includes non-invasive blood analysis utilizing chemical changes and chemical products that are found in the conjunctiva and in the tear film. A transensor mounted in the contact device laying on the cornea or the surface of the eye is capable of evaluating and measuring physical and chemical parameters in the eye including non-invasive blood analysis. The system utilizes eye lid motion and / or closure of the eye lid to activate a microminiature radio frequency sensitive transensor mounted in the contact device. The signal can be communicated by wires or radio telemetered to an externally placed receiver. The signal can then be processed, analyzed and stored. Several parameters can be detected including a complete non-invasive analysis of blood components, measurement of systemic and ocular blood flow, measurement of heart rate and respiratory rate, tracking operations, detection of ovulation, detection of radiation and drug effects, diagnosis of ocular and systemic disorders and the like.
Owner:GEELUX HLDG LTD
Apparatus and method for measuring biologic parameters
ActiveUS8328420B2Increase blood flowReduce in quantityThermometer detailsTelevision system detailsInfraredWireless transmission
Support structures for positioning sensors on a physiologic tunnel for measuring physical, chemical and biological parameters of the body and to produce an action according to the measured value of the parameters. A sensor fitted on the support structures uses a special geometry for acquiring continuous and undisturbed data on the physiology of the body. Signals are transmitted to a remote station by wireless transmission such as by electromagnetic waves, radio waves, infrared, sound and the like or by being reported locally by audio or visual transmission. The physical and chemical parameters include brain function, metabolic function, hydrodynamic function, hydration status, levels of chemical compounds in the blood, and the like. The support structure includes patches, clips, eyeglasses, head mounted gear and the like, containing passive or active sensors positioned at the end of the tunnel with sensing systems positioned on and accessing a physiologic tunnel.
Owner:BRAIN TUNNELGENIX TECH CORP
Contact lens for collecting tears and detecting analytes for determining health status, ovulation detection, and diabetes screening
InactiveUS20070016074A1Increase oxygenationIncreased riskOrganic active ingredientsHeart defibrillatorsConfocalChemical products
Owner:GEELUX HLDG LTD
Simultaneous CT and SPECT tomography using CZT detectors
A method for simultaneous transmission x-ray computed tomography (CT) and single photon emission tomography (SPECT) comprises the steps of: injecting a subject with a tracer compound tagged with a gamma-ray emitting nuclide; directing an x-ray source toward the subject; rotating the x-ray source around the subject; emitting x-rays during the rotating step; rotating a cadmium zinc telluride (CZT) two-sided detector on an opposite side of the subject from the source; simultaneously detecting the position and energy of each pulsed x-ray and each emitted gamma-ray captured by the CZT detector; recording data for each position and each energy of each the captured x-ray and gamma-ray; and, creating CT and SPECT images from the recorded data. The transmitted energy levels of the x-rays lower are biased lower than energy levels of the gamma-rays. The x-ray source is operated in a continuous mode. The method can be implemented at ambient temperatures.
Owner:LOCKHEED MARTIN ENERGY SYST INC
Method and system for generating a cochlear implant program using multi-electrode stimulation to elicit the electrically-evoked compound action potential
InactiveUS7206640B1Increase amplitudeConvenient recordingHead electrodesEvoked compound action potentialConfocal
A multichannel cochlear implant system spatially spreads the excitation pattern in the target neural tissue by either: (1) rapid sequential stimulation of a small group of electrodes, or (2) simultaneously stimulating a small group of electrodes. Such multi-electrode stimulation stimulates a greater number of neurons in a synchronous manner, thereby increasing the amplitude of the extra-cellular voltage fluctuation and facilitating its recording. The electrical stimuli are applied simultaneously (or sequentially at a rapid rate) on selected small groups of electrodes while monitoring the evoked compound action potential (ECAP) on a nearby electrode. The presence of an observable ECAP not only validates operation of the implant device at a time when the patient may be unconscious or otherwise unable to provide subjective feedback, but also provides a way for the magnitude of the observed ECAP to be recorded as a function of the amplitude of the applied stimulus. From this data, a safe, efficacious and comfortable threshold level can be obtained which may be used thereafter as the initial setting of the stimulation parameters of the neurostimulation device, or to guide the setting of the stimulation parameters of the neurostimulation device.
Owner:ADVNACED BIONICS LLC
Optical architectures for microvolume laser-scanning cytometers
InactiveUS6979830B2Reduce power densityMinimizing limitationOptical radiation measurementBioreactor/fermenter combinationsSpectroscopyLaser scanning
Methods and instrumentation for performing charge coupled device (CCD)-based confocal spectroscopy with a laser spot array are provided. The methods and instruments of the invention are useful in any spectroscopic application, including, but not limited to, microscopy and microvolume laser scanning cytometry (MLSC).
Owner:PPD BIOMARKER DISCOVERY SCI
Near infrared risk assessment of diseases
The present invention provides an apparatus and a method for identifying the risk of a clinical condition in a human or animal by correlating Near Infrared (NIR) absorbance spectral data with one or several parameters including a concentration of one or more substances in the skin, a concentration of one or more substances in skin plus subdermal tissue, a score derived from one or more clinical tests like a stress test on a treadmill, coronary angiography, or intravascular coronary ultrasound. The method determines the concentration of a compound in the skin of a human or animal and comprises the steps of placing a part of the skin against a receptor, directing electromagnetic radiation (EMR) from the near-infrared spectrum onto the skin, measuring a quantity of EMR reflected by, or transmitted through, the skin with a detector; and performing a quantitative mathematical analysis of the quantity of EMR to determine the concentration of the compound, for example free and esterfied cholesterol. An example of a clinical condition is cardiovascular disease.
Owner:TYCO HEALTHCARE GRP LP
Data independent acquisition of product ion spectra and reference spectra library matching
ActiveUS8809770B2Stability-of-path spectrometersMolecular entity identificationSingle sampleConfocal
Systems and methods are used to store an electronic record of all product ion spectra of all detectable compounds of a sample. A plurality of product ion scans are performed on a tandem mass spectrometer one or more times in a single sample analysis across a mass range using a plurality of mass selection windows. All sample product ion spectra of all detectable compounds for each mass selection window are produced. All sample product ion spectra for each mass selection window are received from the tandem mass spectrometer using a processor. All sample product ion spectra for each mass selection window are stored as an electronic record of all detectable compounds of the sample using the processor. The electronic record is used to characterize compounds known at the time the electronic record is stored or to characterize compounds that became known after the electronic record was stored.
Owner:ETH ZZURICH +1
Apparatus and method for high energy photodynamic therapy of acne vulgaris and seborrhea
InactiveUS20020128695A1Increasing oxygen pressureStrong enoughElectrotherapyPhotodynamic therapySpectral emissionSpectral bands
An apparatus and method for the phototherapy of different skin conditions, particularly acne vulgaris and seborrhea. The invention transporting compounds, and / or a methylene blue solution. The apparatus includes at least one narrow spectral band light source with spectral emittance concentrated in the violet / blue spectral band and an optical system for controlling spectra and beam parameters of said light source and a mechanical fixture for holding the said light source at an adjustable distance and direction related to the skin treated area, and an electonic unit to control the duration and power and spectral bands of the emitted radiation.
Owner:CURELIGHT
Intra-serum and intra-gel for modeling human skin tissue
InactiveUS6475800B1Diagnostics using spectroscopyScattering properties measurementsConfocalCrosslinking reagent
The invention provides a class of samples that model the human body. This family of samples is based upon emulsions of oil in water with lecithin acting as the emulsifier. These solutions that have varying particle sizes may be spiked with basis set components (albumin, urea and glucose) to simulate skin tissues further. The family of samples is such that other organic compounds such as collagen, elastin, globulin and bilirubin may be added, as can salts such as Na+, K+ and Cl-. Layers of varying thickness with known index of refraction and particle size distributions may be generated using simple crosslinking reagents, such as collagen (gelatin). The resulting samples are flexible in each analyte's concentration and match the skin layers of the body in terms of the samples reduced scattering and absorption coefficients, mums and muma. This family of samples is provided for use in the medical field where lasers and spectroscopy based analyzers are used in treatment of the body. In particular, knowledge may be gained on net analyte signal, photon depth of penetration, photon radial diffusion, photon interaction between tissue layers, photon density (all as a function of frequency) and on instrument parameter specifications such as resolution and required dynamic range (A / D bits required). In particular, applications to delineate such parameters have been developed for the application of noninvasive glucose determination in the near-IR region from 700 to 2500 nm with an emphasis on the region 1000 to 2500 nm (10,000 to 4,000 cm-1).
Owner:GLT ACQUISITION
Method for depth resolved wavefront sensing, depth resolved wavefront sensors and method and apparatus for optical imaging
ActiveUS20110134436A1Less sensitive to reflectionAll optics layout more compactInterferometersUsing optical meansWavefront sensorConfocal
Methods and devices are disclosed for acquiring depth resolved aberration information using principles of low coherence interferometry and perform coherence gated wavefront sensing (CG-WFS). The wavefront aberrations is collected using spectral domain low coherence interferometry (SD-LCI) or time domain low coherence interferometry (TD-LCI) principles. When using SD-LCI, chromatic aberrations can also be evaluated. Methods and devices are disclosed in using a wavefront corrector to compensate for the aberration information provided by CG-WFS, in a combined imaging system, that can use one or more channels from the class of (i) optical coherence tomography (OCT), (ii) scanning laser ophthalmoscopy, (iii) microscopy, such as confocal or phase microscopy, (iv) multiphoton microscopy, such as harmonic generation and multiphoton absorption. In particular, a swept source (SS) is used that drives both an OCT channel and a coherence gated wavefront sensor, where:a) both channels operate according to SS-OCT principles;b) OCT channel integrates over at least one tuning scan of the swept source to provide a TD-OCT image of the object;c) CG-WFS integrates over at least one tuning scan of the swept source to provide an en-face TD-OCT mapping of the wavefront.For some implementations, simultaneous and dynamic aberration measurements / correction with the imaging process is achieved. The methods and devices for depth resolved aberrations disclosed, will find applications in wavefront sensing and adaptive optics imaging systems that are more tolerant to stray reflections from optical interfaces, such as reflections from the microscope objectives and cover slip in microscopy and when imaging the eye, the reflection from the cornea.
Owner:PODOLEANU ADRIAN +1
Thermal Imaging System
InactiveUS20130124039A1Increase blood flowReduce in quantityTelevision system detailsAir-treating devicesInfraredVideo transmission
Owner:BRAIN TUNNELGENIX TECH CORP
Novel optical architectures for microvolume laser-scanning cytometers
InactiveUS20050057749A1Reduce power densityMinimizing limitationOptical radiation measurementBioreactor/fermenter combinationsLaser scanningSpectroscopy
Methods and instrumentation for performing charge coupled device (CCD)-based confocal spectroscopy with a laser spot array are provided. The methods and instruments of the invention are useful in any spectroscopic application, including, but not limited to, microscopy and microvolume laser scanning cytometry (MLSC).
Owner:PPD BIOMARKER DISCOVERY SCI
Fully-automated microfluidic system for the synthesis of radiolabeled biomarkers for positron emission tomography
InactiveUS20080233018A1Isotope introduction to sugar derivativesSugar derivativesChemical synthesisConfocal
The present application relates to microfluidic devices and related technologies, and to chemical processes using such devices. More specifically, the application discloses a fully automated synthesis of radioactive compounds for imaging, such as by positron emission tomography (PET), in a fast, efficient and compact manner. In particular, this application describe an automated, stand-alone, microfluidic instrument for the multi-step chemical synthesis of radiopharmaceuticals, such as probes for PET and a method of using such instruments.
Owner:SIEMENS MEDICAL SOLUTIONS USA INC
Element-specific X-ray fluorescence microscope and method of operation
InactiveUS7183547B2Enhances preferential imagingEnhance the imageMaterial analysis using wave/particle radiationElectric discharge tubesConfocalPeak value
An element-specific imaging technique utilizes the element-specific fluorescence X-rays that are induced by primary ionizing radiation. The fluorescence X-rays from an element of interest are then preferentially imaged onto a detector using an optical train. The preferential imaging of the optical train is achieved using a chromatic lens in a suitably configured imaging system. A zone plate is an example of such a chromatic lens; its focal length is inversely proportional to the X-ray wavelength. Enhancement of preferential imaging of a given element in the test sample can be obtained if the zone plate lens itself is made of a compound containing substantially the same element. For example, when imaging copper using the Cu La spectral line, a copper zone plate lens is used. This enhances the preferential imaging of the zone plate lens because its diffraction efficiency (percent of incident energy diffracted into the focus) changes rapidly near an absorption line and can be made to peak at the X-ray fluorescence line of the element from which it is fabricated. In another embodiment, a spectral filter, such as a multilayer optic or crystal, is used in the optical train to achieve preferential imaging in a fluorescence microscope employing either a chromatic or an achromatic lens.
Owner:CARL ZEISS X RAY MICROSCOPY
Near infrared fluorescent contrast agent and fluorescence imaging
InactiveUS7488468B1Low toxicGood water solubilityUltrasonic/sonic/infrasonic diagnosticsOrganic active ingredientsSolubilityConfocal
A near infrared fluorescent contrast agent comprising a compound having three or more sulfonic acid groups in a molecule, and a method of fluorescence imaging comprising introducing the near infrared fluorescent contrast agent of the present invention into a living body, exposing the body to an excitation light, and detecting near infrared fluorescence from the contrast agent. The near infrared fluorescent contrast agent of the present invention is excited by an excitation light and emits near infrared fluorescence. This infrared fluorescence is superior in transmission through biological tissues. Thus, detection of lesions in the deep part of a living body has been made possible. In addition, the inventive contrast agent is superior in water solubility and low toxic, and therefore, it can be used safely.
Owner:FUJIFILM CORP
System and method for using time-distance characteristics in acquisition, processing, and imaging of t-CSEM data
InactiveUS7502690B2Enhance the imageEasy to processSeismic signal processingSeismology for water-covered areasUltrasound attenuationControlled source electro-magnetic
There is provided herein a system and method of acquiring, processing, and imaging transient Controlled Source ElectroMagnetic (t-CSEM) data in ways that are similar to those used for seismic data. In particular, the instant invention exploits the time-distance characteristics of t-CSEM data to permit the design and execution of t-CSEM surveys for optimal subsequent processing and imaging. The instant invention illustrates how to correct t-CSEM data traces for attenuation and dispersion, so that their characteristics are more like those of seismic data and can be processed using algorithms familiar to the seismic processor. The resulting t-CSEM images, particularly if combined with corresponding seismic images, may be used to infer the location of hydrocarbon reservoirs.
Owner:BP CORP NORTH AMERICA INC
Raman spectroscopic system with integrating cavity
InactiveUS6975891B2Efficient collectionImprove power densityRadiation pyrometryRaman scatteringSpectral widthSpectrum analyzer
The present invention provides an apparatus for measurement of Raman scattered radiation comprising. The apparatus comprises at least one source of electromagnetic radiation for producing an electromagnetic radiation beam characterized by a narrow spectral width, an integrating cavity having an interior and an exterior, wherein a sample is placed in said interior. The integrating cavity further having at least one port for insertion of the sample in the interior and for transmission of the electromagnetic radiation into and out from the interior, the at least one port extending from the exterior to said interior of said integrating cavity. The integrating cavity also comprises a first optical element for transmitting the electromagnetic radiation into the interior of the integrating cavity through the at least one port, and a second optical element for collecting Raman scattered electromagnetic radiation from the sample through the at least one port. The apparatus also comprises a spectrum analyzer for determining spectral composition of the Raman scattered electromagnetic radiation, a detector for measuring the Raman scattered electromagnetic radiation; and a system for determining concentration of at least one chemical compound from the measured Raman scattered electromagnetic radiation. The apparatus may also comprise a radiation expanding element. A method for measuring the concentration of one or more chemical compounds in a sample using Raman scattering is also provided.
Owner:TYCO HEALTHCARE GRP LP
System and method for enhanced vertical resolution magnetic resonance imaging logs
InactiveUS6337568B1Electric/magnetic detection for well-loggingMeasurements using NMR spectroscopyLithologyMicro imaging
An interpretation method and system for NMR echo-train data in thinly laminated sequences. The invention uses geological information obtained at higher vertical resolution, such as using Electric Micro Imaging, to enhance the vertical resolution of echo-train data, and thus avoids log interpretations in which the hydrocarbon potential of the formation can be misread because low resolution logs tend to provide an average description of the formation. Such averaging is especially problematic in thinly laminated sequences that consist of highly permeable and porous sand layers and less permeable silt or essentially impermeable shale layers. In a preferred embodiment, using the additional high-resolution formation information one can estimate the typical T2-spectra of lithological laminae, and significantly enhance the permeability estimate in the laminated sequences. In another aspect the system and method of the preferred embodiment use neural network(s) to further enhance the resolution of a particular log measurement. The method and system are applicable to any temporal data from other logging tools, such as the thermal neutron decay log and others. The system and method enable proper evaluation of the high potential of thinly laminated formations, which may otherwise be overlooked as low permeable formations.
Owner:HALLIBURTON ENERGY SERVICES INC
Temperature controlled facial mask with area-specific treatments
A temperature controlled cosmetic treatment facial mask with area-specific treatments of the present invention includes a substantially planar mask body which is formed with cut-outs for a person's eyes, nose, and mouth. The mask may include a number of large and small area treatment zones in combination with asymmetrical treatment zones suitable for treatment of specific and localized skin conditions. The treatments zones are coated with skin treatments, such as compounds, lotions, gels, and the like as are known in the facial treatment, cosmetics, spa and medical industry. The mask may include a self-heating or cooling substrate to provide temperature control to the face mask and each mask may include heating areas, cooling areas, or both. A system is also provided that includes an imaging device that feeds its output to a central computer system having an image analyzer, CPU, memory and Look Up Table, and face map for determining specific treatment requirements for the particular patient. An output from the central computer system is provided to a treatment deposition device which deposits various treatments onto an intermediate membrane layer to generate a custom temperature controlled facial mask with area-specific treatments for that particular patient.
Owner:FOREVER YOUNG INT
Method and apparatus for determining the nature of subterranean reservoirs using refracted electromagnetic waves
InactiveUS6859038B2Increase success rateWater resource assessmentDetection using electromagnetic wavesOcean bottomConfocal
Methods and devices are disclosed for determining if hydrocarbons or water is present in a subterranean reservoir are described. Certain embodiments involve an electromagnetic field applied by a transmitter on the seabed and detected by at least one antenna also on the seabed, wherein a refracted wave component is sought in the wave field response, and is analyzed to determine the nature and contents of the resevoir.
Owner:ELECTROMAGNETIC GEOSERVICES ASA
System and system for robot mounted sensor
ActiveUS20080165344A1Material analysis by optical meansSpectrometry/spectrophotometry/monochromatorsConfocalRobotic arm
An apparatus and method for the remote analysis and identification of unknown compounds. A robotic arm positions a sensor on a surface. The sensor unit has a monitoring mechanism to monitor separation between the sensor unit and the surface when placed in contact with the surface to maintain the separation substantially constant. An illumination source illuminates the region of interest to produce scattered photons from an unknown compound. The scattered photons are collected by an optical system and delivered to a spectroscopic detector for analysis and identification. An algorithm is applied to the data generated by the spectroscopic detector to identify the unknown compound.
Owner:CHEMIMAGE CORP
Apparatus and method for optimizing photosynthetic growth in a photo bioreactor
InactiveUS20090291485A1Light utilization efficiencyReduce energy costsBioreactor/fermenter combinationsBiological substance pretreatmentsProcess systemsPhotosynthetic growth
A system and methods for enhancing mass production of algae, diatoms or other photosynthetic organism is described. The system and methods are useful in applications such as energy production, fuels, foods, pharmaceuticals, plastics, and CO2 fixation. The system and methods involve the use of a submersed rotating pole(s) on which lights are branched out at strategic intervals in order to appropriately increase contact between photosynthetic water-based organisms and light. Rotation can timed so as to disperse light and / or nutrients when the organism is in a receiving mode. A process flow system is also described which can be scaled for the mass production of photosynthetic based organism. This process system makes use of centralized automatable controls and linear or parallel growth tanks. The system can be used for continuous or batch methods of production of bio-mass whose values such as lipids or carbohydrate can be extracted for the production of fuels or other byproducts.
Owner:ENNESYS
Microarray detector and methods
InactiveUS7354389B2Bioreactor/fermenter combinationsBiological substance pretreatmentsAnalyteConfocal
A detector for optical analysis of a biochip determines the focal position of a plurality of analytes on the biochip using one or more registration markers on the biochip, wherein the analytes and the registration marker are illuminated by different light sources. Therefore, contemplated configurations will significantly reduce overall focusing time and automate proper positioning of the biochip, while allowing to determine a focal position without photobleaching or other undesirable effects on optically labile compounds. Thus, automated analyses can be performed without manual user intervention.
Owner:AUTOGENOMICS
Apparatus and method for measuring biologic parameters
ActiveUS20120316459A1Increase blood flowReduce in quantityUltrasonic/sonic/infrasonic diagnosticsBody temperature measurementInfraredVideo transmission
Owner:BRAIN TUNNELGENIX TECH CORP
Photomask blank, photomask and fabrication method thereof
ActiveUS20070020534A1Increase etch rateLow metal percentage contentPhotomechanical apparatusSemiconductor/solid-state device manufacturingChromium CompoundsConfocal
A light-shielding film for exposure light is formed on one principal plane of a transparent substrate made of quartz or the like that serves as a photomask substrate. The light-shielding film can serve not only as the so-called “light-shielding film” but also as an anti-reflection film. In addition, the light-shielding film has a total thickness of 100 nm or less, 70% or more of which is accounted for by the thickness of a chromium compound that has an optical density (OD) per unit thickness of 0.025 nm−1 for light having a wavelength of 450 nm. In the case where the photomask blank is used for fabricating a mask designed for ArF exposure, the thickness and composition of the light-shielding film are selected in such a manner that the OD of the light-shielding film is 1.2 to 2.3 for 193 or 248 nm wavelength light.
Owner:SHIN ETSU CHEM IND CO LTD +1
Scanning beam optical imaging system for macroscopic imaging of an object
A new high resolution confocal and non-confocal scanning laser macroscope is disclosed which images macroscopic specimens in reflected light, transmitted light, fluorescence, photoluminescence and multi-photon fluorescence. The optical arrangement of a scanning laser macroscope has been altered to include a liquid-immersion laser scan lens, providing higher numerical aperture and higher resolution; and higher intensity at the focal spot, which makes the macroscope particularly well suited for multiphoton imaging. Several applications of the imaging system are described. A liquid-immersion laser scan lens with spring-loaded bottom element and method for containing the immersion liquid are also disclosed.
Owner:BIOMEDICAL PHOOMETRICS
Method and device for measuring appearance and wall thickness of sphere by combining differential confocal and point-diffraction interference
The invention belongs to the field of optical precision measurement and relates to a method and a device for measuring the appearance and the wall thickness of a sphere by combining a differential confocal confocal technology and point-diffraction interference. The method realizes the high-precision rapid measurement on the appearance of the outer surface of the sphere by using the point-diffraction interference, the rotation of the measured sphere and the splice of a measuring sub-aperture; and the appearance and wall thickness of the inner surface and the outer surface of a key area of a transparent or semitransparent sphere can be scanned and measured point by point by using the differentia confocal technology. The invention organically integrates a point-diffraction interference technology and the differentia confocal technology so as to realize the synchronous measurement on the appearance and the wall thickness of the inner surface and the outer surface of the sphere, and aims to solve the difficult problems that the traditional AFM or a single confocal sensor and the other scanning methods have low measuring speed, low efficiency, easy leakage in measurement and the like during measuring the surface of the sphere. The invention has broad application prospect in the fields of testing the appearance and the wall thickness of a laser fusion pellet, the appearance and the outline of a spherical surface and the like.
Owner:BEIJING INSTITUTE OF TECHNOLOGYGY
Method and instruments for non-invasive analyte measurement
The present invention is related to optical non-invasive methods and instruments to detect the level of analyte concentrations in the tissue of a subject. The spectra of mid-infrared radiation emitted from a subject's body are altered corresponding to the concentration of various compounds within the radiating tissue. In one aspect of the invention, an instrument measures the level of mid-infrared radiation from the subject's body surface, such as the eye, and determines a specific analyte's concentration based on said analyte's distinctive mid-infrared radiation signature.
Owner:OCULIR
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